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  • Principle Investigator
  • Publications
  • Lab Members
  • Research Area
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    • Principle Investigator
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MOLECULAR IMMUNOLOGY LAB 

Publications

  1. Chaudhari R, Dasgupta M, Nigam D and Kodgire P* Engineering Outer Membrane Vesicles (OMVs) carrying OmpA from S. Typhimurium for targeted modulation of human B-cell function through AID expression and class switch recombination. Microb. Pathog., 2025, 107918 (In Press).

  2. Chaudhari R, Dasgupta M and Kodgire P* Unraveling the impact of Outer Membrane Protein, OmpA, from S. Typhimurium on aberrant AID expression and IgM to IgA class switching in human B-cells. Immunology, 2025, 175(3):359-372.

  3. Jaiswal S, Dhingra I, Joshi A* and Kodgire P*. Efficacious bioremediation of pesticide-contaminated water using immobilized organophosphorus acid anhydrolase–FL variant (OPAA-FL) enzyme in a lab-scale bioreactor. J. Water Process Eng., 2025, 71, 107357.

  4. Singh B and Kodgire P*. Refolding Dynamics and Immunoinformatic Insights into Vibrio cholerae OmpA, OmpK, and OmpV for Vaccine Applications. Int. J. Biol. Macromol., 2024, 283(Pt 2):137643.

  5. Jaiswal S, Singh V, Jain M, Ahmed J, Joshi A* and Kodgire P*. Dual colorimetric and fluorometric biosensing assays for organophosphate pesticide detection using monomeric Teal Fluorescent Protein (mTFP1)-Organophosphate degrading enzyme fusion proteins expressed in E. coli. ACS ES&T Water, 2024, 252(Pt 2):118888.

  6. Sharma S, Dasgupta M, Vadaga BS, Kodgire P*. Unfolding the Symbiosis of AID, Chromatin Remodelers, and Epigenetics - The ACE Phenomenon of Antibody Diversity. Immunol. Lett., 2024, 269:106909.

  7. Jaiswal S, Singh B, Dhingra I, Joshi A* and Kodgire P* Bioremediation and Bioscavenging for elimination of Organophosphate threats: An approach using enzymatic advancements. Environ. Res., 2024, 252(Pt 2):118888.

  8. Vikhrankar S, Satbhai S, Kulkarni P, Ranbhor R, Ramakrishnan V and Kodgire P Enzymatic Routes for Chiral Amine Synthesis: Protein Engineering and Process Optimization. Biologics: Targets and Therapy., 2024, 18:165-179.

  9. Malik  K and Kodgire P* Insights into the molecular mechanisms of H. pylori-associated B-cell Lymphoma. Crit. Rev. Microbiol., 2024, 1–17. 

  10. Jaiswal A, Roy R, Tamrakar A, Singh AK, Kar P and Kodgire P* Activation-induced cytidine deaminase an antibody diversification enzyme interacts with chromatin modifier UBN1 in B-cells. Sci. Rep. 2023, 13(1):19615.

  11. Vyas T, Jaiswal S, Choudhary S, Kodgire P* and Joshi AB*, Recombinant Organophosphorus acid anhydrolase (OPAA) enzyme-carbon quantum dot (CQDs)-immobilized thin film biosensors for the specific detection of Ethyl Paraoxon and Methyl Parathion in water resources, Environ. Res., 2023, 243:117855.

  12. Singh B, Jaiswal S and Kodgire P*. Outer membrane proteins and vesicles as promising vaccine candidates against Vibrio spp. infections. Crit. Rev. Microbiol., 2023, 5:1-17.

  13. Jaiswal A, Jain M, Singh K and Kodgire P*. Heterologous expression of hAID in E. coli leads to the production of a splice isoform of AID: hAIDδC, a mystery to be explored. Protein Expr Purif., 2022, 199:106149.

  14. Chaudhari R, Singh K and Kodgire P*. Biochemical and Molecular Mechanisms of Antibiotic Resistance in Salmonella spp. Res. Microbiol., 2022, 103985.

  15. Sarkar S, Gogoi M, Mahato M, Joshi AB, Baruah AJ, Kodgire P and Boruah P. Biosensors for detection of prostate cancer: a review. Biomed Microdevices. 2022, 24(4):32.

  16. Tamrakar A and Kodgire P*. HomA and HomB, outer membrane proteins of Helicobacter pylori down-regulate activation-induced cytidine deaminase (AID) and Ig switch germline transcription and thereby affect class switch recombination (CSR) of Ig genes in human B-cells. Mol. Immunol., 2022, 142: 37-49.

  17. Vyas T, Singh V, Kodgire P* and Joshi A*, Insights in detection and analysis of organophosphates using Organophosphorus acid Anhydrolases (OPAA) enzyme-based biosensors, Crit. Rev. Biotechnol., 2022, 3:1-19. 

  18. Tamrakar A, Singh R, Kumar A, Makde DR, Ashish and Kodgire P*. Biophysical characterization of the homodimers of HomA and HomB, outer membrane proteins of Helicobacter pylori. Sci. Rep. 2021, 11(1):24471.

  19. Jain M, Yadav P, Joshi B, Joshi A and Kodgire P*., Recombinant organophosphorus hydrolase (OPH) expression in E. coli for the effective detection of organophosphate pesticides, Protein Expr Purif. 2021, 186:105929.

  20. Jain M, Yadav P, Joshi B, Joshi A* and Kodgire P*. A novel biosensor for the detection of organophosphorus (OP)-based pesticides using organophosphorus acid anhydrolase (OPAA)-FL variant, Appl. Microbiol. Biotechnol. 2021, 105(1):389-400

  21. Singh AK, Tamrakar A, Jaiswal A, Kanayama N and Kodgire P*, SRSF1-3, a splicing and somatic hypermutation regulator, controls transcription of IgV genes via chromatin regulators SATB2, UBN1 and histone variant H3.3, Mol. Immunol., 2020, 119: 69-82.

  22. Jaiswal A, Singh AK, Tamrakar A and Kodgire P*, Unfolding the Role of Splicing Factors and RNA Debranching in AID Mediated Antibody Diversification, Int. Rev. Immunol. 2021, 40(4):289-306.

  23. Jain N, Mishra SK, Shankar U, Jaiswal A, Sharma TK, Kodgire P and Kumar A., G-quadruplex stabilization in the ions and maltose transporters gene inhibit Salmonella enterica growth and virulence, Genomics, 2020, 112(6): 4863–4874.

  24. Shankar U, Jain N, Majee P, Kodgire P, Sharma TK and Kumar A, Exploring Computational and Biophysical Tools to Study the Presence of G-Quadruplex Structures: A Promising Therapeutic Solution for Drug-Resistant Vibrio cholerae, Front. Genet. 2020, 11:935.

  25. Singh AK, Tamrakar A, Jaiswal A, Kanayama N, Agarwal A, Tripathi P and Kodgire P*, Splicing regulator SRSF1-3 that controls somatic hypermutation of IgV genes interacts with topoisomerase 1 and AID, Mol. Immunol. 2019, 116:63-72.

  26. Singh AK, Jaiswal A and Kodgire P*, AID preferentially targets the top strand in nucleosome sequences, Mol. Immunol. 2019, 112:198-205.

  27. Jain M, Yadav P, Joshi A and Kodgire P*, Advances in detection of hazardous organophosphorus compounds using organophosphorus hydrolase based biosensors, Crit. Rev. Toxicol. 2019, 49(5):387-410.

  28. Choudhary M, Tamrakar A, Singh AK, Jain M, Jaiswal A and Kodgire P*, AID Biology: A Pathological and Clinical Perspective, Int. Rev. Immunol., 2018, 37(1): 37-56.

  29. Bhattacharya A, Bhowmik S, Singh AK, Kodgire P, Das A and Mukherjee T, Direct Evidence of Intrinsic Blue Fluorescence from Oligomeric Interfaces of Human Serum Albumin, Langmuir, 2017, 33(40): 10606-15.

  30. Tamrakar A, Singh AK, Chaudhary M, and Kodgire P*. Fighting with Gram-negative Enemy: Can Outer Membrane Proteins Aid in the Rescue?, Chem. Biol. Lett., 2017, 4(1): 9-19. [in Special Issue - Diagnosis and Therapy of Infectious Diseases].

  31. Kodgire P, Mukkawar P, Ratnam S, Martin TE and Storb U. Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID, J. Exp. Med., 2013, 210(7): 1481-92.

  32. Kodgire P, Mukkawar P, North JA, Poirier MG and Storb U. Nucleosome stability dramatically impacts the targeting of somatic hypermutations, Mol. Cell. Biol. 2012 32(10): 2030-2040.

  33. Tanaka A, Shen HM, Ratnam S, Kodgire P and Storb U. Attracting AID to targets of somatic hypermutation, J. Exp. Med. 2010, 207(2): 405-415.

  34. Kodgire P and Rao KK. ScoC regulates hag expression at multiple points in Bacillus subtilis. Microbiology, 2009, 155: 142-149. 

  35. Kodgire P, Dixit M and Rao KK. ScoC and SinR negatively regulate epr by corepression in Bacillus subtilis. J. Bacteriol., 2006, 188: 6425-6428.

  36. Kodgire P and Rao KK. A dual mode of regulation of flgM by ScoC in Bacillus subtilis. Can. J. Microbiol., 2009, 55: 983–989. 

  37. Murudkar CS, Kodgire P and Rao KK. The carboxy terminal domain of Epr, a minor extracellular serine protease, is essential for the swarming motility of Bacillus subtilis 168. FEMS Microbiol. Lett., 2006, 257: 24-31.

  38. Kar S, Pradhan B, Sinha RK, Kundu T, Kodgire P, Rao KK, Puranik VG and Lahiri GK. Synthesis, structure, redox, NLO and DNA interaction aspects of [{(L'-'")2RuII}3(m3-L)]3+ and [(L')2RuII(NC5H4S-)]+[L3- = 1,3,5-triazine-2,4,6-trithiolato, L'-'" = arylazopyridine] Dalton Trans., (Royal Society of Chemistry Publication), 2004, 1752–1760.

MOLECULAR IMMUNOLOGY LAB

1B501, POD Building

Mehta Family School of Biosciences and Biomedical Engineering

Indian Institute of Technology Indore.

Khandwa Road, Simrol, Indore - 453552.

Madhya Pradesh, INDIA.

Phone: 91 731 660 3355

E-mail: pkodgire@iiti.ac.in

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