Organic synthesis is central to our research. We use organic reactions to build and diversify small molecules, supported by computational drug discovery and pharmacokinetics, to develop therapeutic candidates for antimicrobial resistance and cancer.
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Therapeutic research programmes
Therapeutic research programmes
Cancer therapeutics
Targeting cancer epigenetics and immune regulation with small molecules to explore new therapeutic strategies.
Antimalarial discovery
Designing small-molecule therapeutic candidates for artemisinin-resistant malaria through synthesis and computational discovery.
Antibiotics & adjuvants
Developing new antibiotics and antibiotic adjuvants against Gram-negative ESKAPE pathogens to address antimicrobial resistance.
AI/ML-enabled discovery
We develop computational pipelines that combine artificial intelligence, machine learning and molecular modelling to support early-stage drug discovery. These tools guide molecular design and prioritisation alongside our experimental synthesis programme.
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