Welcome to Dimpy's Lab!
Follow us at https://x.com/Dimpy_IISERB
and at https://www.linkedin.com/in/dimpy-kalia-96411077/
Watch Dimpy's interview by Chemistry Club, IISER Bhopal: https://www.youtube.com/watch?v=0Sg3-Y2Qu6o
Watch Dimpy's lab research at IISER Bhopal: https://www.youtube.com/watch?v=9r6wWt_c6TI&list=PLf-oVIzkMo-dYVyaSQDZbYOY2CnGrlB2B&index=6
Lab News
January 2026: Our StapleAld and LAP-StapleAld technologies for disulfide bioconjugation is published in Journal of the American Chemical Society
April 2025: Our lab has been awarded the MIT-IIT Kanpur Seed Fund grant with Prof. Elizabeth Nolan's lab at MIT (Chemistry) which will fund visits of personnel between the two labs enabling us to join forces to study bacterial signaling mechanisms using chemical biology approaches! These funds will enable combining our lab's skillset in synthetic organic chemistry and chemoproteomics with the Nolan lab's expertise in bacterial siderophores to shed light on the fascinating yet poorly understood c-di-GMP bacterial signaling mechanisms.
March 2025: Veena and Rushikesh are awarded the Best Poster Award in the in-house yearly departmental meeting, Interactions 2025. They presented their work on "Photocrosslinkable c-di-GMP analogs for chemoproteomic applications". Congratulations Veena and Rushikesh!
February 2025: Dimpy is awarded the Thieme Chemistry Journals Award for 2025 by the editorial boards of Synthesis, Synlett, Synfacts as well as of the open-access journals portfolio!
January 2025: Neha joins the lab as a PhD student. Welcome!
November 2024: Bhaskar's INSPIRE proposal for PhD fellowship on fabrication on Antibody-Drug Conjugates is selected for funding. Congratulations Bhaskar!
September 2024: Veena is selected to present a poster on her work on photocrosslinkable c-di-GMP probes at the EMBO Chemical Biology 2024 conference to be held in Germany. Congratulations Veena!
August 2024: Dimpy presents a talk on the lab's BHoPAL technology at the 11th annual meet of Chemical Biology Society (India) held at the Adichunchanagiri University.
August 2024: PhD students Bhaskar and Ayushi, and Masters project students Ashis, Rushikesh, and Thrisha join the lab. Welcome!
July 2024: Dimpy visits Ireland and presents an invited talk at the Ireland Chemical Biology Conference held at the University of Galway.
June 2024: Dimpy visits the US and presents invited talks at the Gordon Research Conference in Bioorganic Chemistry, MIT Chemistry, and Tufts Chemistry.
January 2024: Our BHoPAL (Baylis Hillman orchestrated Protein Aminothiol Labelling) technology is published in Nature Communications. This work has been covered by more than 26 media outlets including The Times of India, The Economic Times and Dainik Bhaskar.
January 2024: PhD students Pankaj and Rashid, and project JRF Bhaskar join the lab. Welcome!
December 2023: One project JRF position available. Motivated candidates interested in Chemical Biology and Organic Chemistry are encouraged to apply (link).
November 2023: Sangeeta is awarded SERB International Travel Support to present a talk on her work on protein bioconjugation at the 13th International Symposium on Bioorganic Chemistry (ISBOC-13) to be held at Singapore. Congratulations Sangeeta!
October 2023: Dimpy presents the lab's work on N-terminal cysteine bioconjugation at the Women in Science conference (WiSC@IITK-2023) at IIT Kanpur.
July 2023: Vishnu's INSPIRE proposal for PhD fellowship on the chemical biology of bacterial c-di-GMP signaling is selected for funding. Congratulations Vishnu!
April 2023: Dimpy presents the lab's work on Cys detection probe development and Cys-bioconjugation in the Redox Chemical Biology of Health and Disease conference at IISER Pune.
March 2023: Chhaya is awarded the Best Poster Award in the in-house yearly departmental meeting, Interactions 2023. She presented her work on developing covalent inhibitors of c-di-GMP synthases. Congratulations Chhaya!
September 2022: Pooja joins the lab as a project JRF.
August 2022: BS-MS students Anmol, Deepa and Gourav join the lab for their thesis work.
July 28-31, 2022: Dimpy presents an invited talk at ‘FORCE-IICS’ conference held in Agra. Talk title: Sensitive free cysteine detection and rapid protein bioconjugation via facile Michael addition-elimination reactions.
July 7-9, 2022: Dimpy presents an invited "CRSI-ACS Women in Chemical Science Lecture” at 29th CRSI-NSC and CRSI-ACS Symposium held at IISER Mohali. Talk title: Cascaded 1,2 aminothiol-triggered Michael addition-elimination reactions for nanomolar cysteine detection and rapid protein bioconjugation.
July 2022: Our work on the development of sensitive MADELCY TOF probes for detecting free Cys, ACY-1, and imaging cellular Cys is published in Analyst.
April 13, 2022: Dimpy is awarded the prestigious SERB POWER grant.
November 25-28, 2021: Dimpy presents an invited talk at XXI NOST-Organic Chemistry conference held in Chennai. Talk title: Cascaded 1,2-aminothiol-triggered reactions of Michael acceptors.
August 5-6, 2021: Dimpy presents an invited talk at RSC-IISERB Desktop Symposium. Talk title: Tweaking maleimides for improved bioconjugation.
January 1, 2021: PhD student Suman joins the group.
December 11, 2020: Dimpy is invited to serve as a member of the international advisory board of the Eur. J. Org. Chem.
October 31-November 1, 2020: Sangeeta presents a talk on her PhD research at the XVI J-NOST 2020 conference, entitled: "In-situ generated ylides for aldehyde-mediated bioconjugation".
August 28, 2020: Dimpy presents an invited talk in a webinar session on “Women in Organic Chemistry (WOC 2020)” held at the Ravenshaw University. Talk title: Exocyclic olefinic maleimides as versatile scaffolds for bioconjugation.
November 2019: Our work on the development of a technically straightforward high-yielding aldehyde-mediated bioconjugation method is published in ChemComm.
August 2019: PhD student Veena and 5th yr BS-MS project students, Anisha, Nanditha and Shahabas join the group.
March 2019: Dimpy has been awarded Early Career Research Award (ECRA) by SERB.
February 25-28, 2019: Dimpy presents an invited talk at the IIT Bombay Diamond Jubilee Chemistry Symposium. Talk title: Exocyclic olefinic maleimides as versatile scaffolds for bioconjugation.
January 2019: Chemistry Ph.D. students, Chhaya and Sangeeta, join the group.
December 22-24, 2018: Dimpy presents an invited talk at the National Bioorganic Chemistry Conference held at the NISER Bhubaneswar. Talk title: Exocyclic olefinic maleimides — From stable thiol bioconjugation to N-terminal protein modification.
October 3, 2018: Dimpy presents an invited talk at the Departmental Seminar Series at the Department of Chemical Sciences, IISER Kolkata. Talk title: Maleimides—Versatile scaffolds for chemical biology.
August 2018: Chemistry Ph.D. students, Dastgir and Mudassir, and 5th yr BS-MS project student, Govind join the group.
August 19-22, 2018: Dimpy presents an invited talk at the decennial year meeting of the "Chemical Frontiers 2018" meeting organized by IIT Bombay in Goa. Talk title: Exocyclic olefinic maleimides: From stable thiol bioconjugation to N-terminal protein modification.
July 13-15, 2018: Dimpy presents an invited talk at the 23rd CRSI National Symposium in Chemistry held at IISER Bhopal. Talk title: Efficacious approaches for stable thiol bioconjugation.
May-July 2018: BS-MS students, Tarun Jaiswal and Shubham Patil perform summer projects in the lab.
April 2018: Sangeeta joins the lab as a project JRF student.
January 2018: Dimpy moves to the Department of Chemistry at IISER Bhopal from Savitribai Phule Pune University.
September 4-7, 2017: Dimpy presents an invited talk at the 7th Chemical Protein Synthesis Conference held at Haifa, Israel. Talk title: Endowing stability to thio-maleimide protein bioconjugates.
July 29, 2017: Dimpy presents an invited outreach lecture at the Hislop College, Nagpur organized by RSC West India section, July 29th 2017. Talk title: Cancer: Chemistry to the Rescue.
