Welcome to Dimpy's Lab!
Follow us at https://twitter.com/Dimpy_IISERB
Available positions: There are multiple PhD student vacancies in the lab currently (for the August 2024 semester).
There are multiple vacancies in the lab currently for motivated PhD and BS-MS students to work on exciting pure organic synthesis as well as chemical biology projects!
Lab News
January 2024: Our BHoPAL (Baylis Hillman orchestrated Protein Aminothiol Labelling) technology just out in Nature Communications: Link: https://lnkd.in/dm3XPdSB.
January 2024: Bhaskar joins the lab as a project JRF student.
December 2023: One project JRF position available. Motivated candidates interested in Chemical Biology and Organic Chemistry are encouraged to apply (link).
November 2023: Sangeeta got SERB International Travel Support to present a talk on her work on protein bioconjugation at the "13th International Symposium on Bioorganic Chemistry (ISBOC-13) Link" to be held at Singapore on 18-20 December, 2023. Congratulations Sangeeta!
October 2023: Dimpy presents the lab's work on N-terminal cysteine bioconjugation in Women in Science conference (WiSC@IITK-2023) at IIT Kanpur Link.
July 2023: Vishnu's INSPIRE proposal for PhD fellowship on the chemical biology of bacterial c-di-GMP signaling is selected for funding. Congratulations Vishnu!
April 2023: Dimpy presents the lab's work on Cys detection probe development and Cys-bioconjugation in the Redox Chemical Biology of Health and Disease conference at IISER Pune.
March 2023: Chhaya is awarded the Best Poster Award in the in-house yearly departmental meeting, Interactions 2023. She presented her work on developing covalent inhibitors of c-di-GMP synthases. Congratulations Chhaya!
September 2022: Pooja joins the lab as a project JRF.
August 2022: BS-MS students Anmol, Deepa and Gourav join the lab for their thesis work.
July 28-31, 2022: Dimpy presents an invited talk at ‘FORCE-IICS’ conference held in Agra. Talk title: Sensitive free cysteine detection and rapid protein bioconjugation via facile Michael addition-elimination reactions.
July 7-9, 2022: Dimpy presents an invited "CRSI-ACS Women in Chemical Science Lecture” at 29th CRSI-NSC and CRSI-ACS Symposium held at IISER Mohali. Talk title: Cascaded 1,2 aminothiol-triggered Michael addition-elimination reactions for nanomolar cysteine detection and rapid protein bioconjugation.
July 2022: Our work on the development of sensitive MADELCY TOF probes for detecting free Cys, ACY-1, and imaging cellular Cys is published in Analyst.
April 13, 2022: Dimpy is awarded the prestigious SERB POWER grant.
November 25-28, 2021: Dimpy presents an invited talk at XXI NOST-Organic Chemistry conference held in Chennai. Talk title: Cascaded 1,2-aminothiol-triggered reactions of Michael acceptors.
August 5-6, 2021: Dimpy presents an invited talk at RSC-IISERB Desktop Symposium. Talk title: Tweaking maleimides for improved bioconjugation.
January 1, 2021: PhD student Suman joins the group.
December 11, 2020: Dimpy is invited to serve as a member of the international advisory board of the Eur. J. Org. Chem.
October 31-November 1, 2020: Sangeeta presents a talk on her PhD research at the XVI J-NOST 2020 conference, entitled: "In-situ generated ylides for aldehyde-mediated bioconjugation".
August 28, 2020: Dimpy presents an invited talk in a webinar session on “Women in Organic Chemistry (WOC 2020)” held at the Ravenshaw University. Talk title: Exocyclic olefinic maleimides as versatile scaffolds for bioconjugation.
November 2019: Our work on the development of a technically straightforward high-yielding aldehyde-mediated bioconjugation method is published in ChemComm.
August 2019: PhD student Veena and 5th yr BS-MS project students, Anisha, Nanditha and Shahabas join the group.
March 2019: Dimpy has been awarded Early Career Research Award (ECRA) by SERB.
February 25-28, 2019: Dimpy presents an invited talk at the IIT Bombay Diamond Jubilee Chemistry Symposium. Talk title: Exocyclic olefinic maleimides as versatile scaffolds for bioconjugation.
January 2019: Chemistry Ph.D. students, Chhaya and Sangeeta, join the group.
December 22-24, 2018: Dimpy presents an invited talk at the National Bioorganic Chemistry Conference held at the NISER Bhubaneswar. Talk title: Exocyclic olefinic maleimides — From stable thiol bioconjugation to N-terminal protein modification.
October 3, 2018: Dimpy presents an invited talk at the Departmental Seminar Series at the Department of Chemical Sciences, IISER Kolkata. Talk title: Maleimides—Versatile scaffolds for chemical biology.
August 2018: Chemistry Ph.D. students, Dastgir and Mudassir, and 5th yr BS-MS project student, Govind join the group.
August 19-22, 2018: Dimpy presents an invited talk at the decennial year meeting of the "Chemical Frontiers 2018" meeting organized by IIT Bombay in Goa. Talk title: Exocyclic olefinic maleimides: From stable thiol bioconjugation to N-terminal protein modification.
July 13-15, 2018: Dimpy presents an invited talk at the 23rd CRSI National Symposium in Chemistry held at IISER Bhopal. Talk title: Efficacious approaches for stable thiol bioconjugation.
May-July 2018: BS-MS students, Tarun Jaiswal and Shubham Patil perform summer projects in the lab.
April 2018: Sangeeta joins the lab as a project JRF student.
January 2018: Dimpy moves to the Department of Chemistry at IISER Bhopal from Savitribai Phule Pune University.
September 4-7, 2017: Dimpy presents an invited talk at the 7th Chemical Protein Synthesis Conference held at Haifa, Israel. Talk title: Endowing stability to thio-maleimide protein bioconjugates.
July 29, 2017: Dimpy presents an invited outreach lecture at the Hislop College, Nagpur organized by RSC West India section, July 29th 2017. Talk title: Cancer: Chemistry to the Rescue.