Framing the Response to Emerging Virus Infections (S2) (October 14—18, 2018)

• Scientific Organizers: Ralph A. Tripp, Suresh Mahalingam, John W. Lowenthal, Andrew G. Bean and [Dr. Joseph Sriyal Malik Peiris (born 1949)]

• [LOCATION:]   Lee Shau Kee Lecture Centre, Centennial Campus, The University of Hong Kong, Pok Fu Lam, Hong Kong

• Organized in collaboration with the Croucher Foundation and The University of Hong Kong

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DEADLINES:

• *All deadlines end at 11:59 PM US Mountain Standard Time
• Travel Award Deadline: Jun 27, 2018 [details]
• Scholarship Deadline: Jun 27, 2018 [details]
• Discounted Abstract Deadline: Jun 27, 2018 [details]
• Abstract Deadline: Jul 17, 2018 [details]
• Discounted Registration Deadline: Aug 14, 2018 [details]

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Conference Program   

SUNDAY, OCTOBER 14

• 16:00—20:00 :   Arrival and Registration  ( Hotel Jen Lobby )

• 18:00—20:00 :   Welcome Mixer  [...]   ( Hotel Jen Lobby )

MONDAY, OCTOBER 15

• 08:00—09:00 :   Poster Setup   ( Lecture Hall LG 2 )
• 09:00—17:30 :   Poster Viewing   ( Lecture Hall LG 2 )
• 09:00—10:00 :    Welcome and Keynote Address   ( Grand Hall )
  • • *   [Dr. Joseph Sriyal Malik Peiris (born 1949)], University of Hong Kong, Hong Kong
    • Gabriel M. Leung, Dean of Medicine, University of Hong Kong, Hong Kong
      • • Opening Remarks 
    • [Dr. Peter Daszak (born 1965)], EcoHealth Alliance, USA
      • • Emerging Infectious Disease Emergence
• 10:00—12:30 :   Mosquito Borne Viruses - Biology and Host Interactions (Grand Hall)
  • • * Lisa E. Gralinski, University of North Carolina, USA
    • [Dr. Scott C. Weaver (born 1957)], University of Texas Medical Branch, USA
      • • Urban Arboviruses: History, Evolution and Mechanisms of Emergence
    • Coffee Break
    • Suresh Mahalingam, Griffith University, Australia
      • • Alphavirus Inflammatory Disease Mechanisms and Approaches to Therapy
    • [Dr. Michael S. Diamond (born 1964)], Washington University School of Medicine, USA
      • • Host Factors Required for Alphavirus Infection: The Identification of Mxra8 as an Entry Receptor
    • Ali Zaid†, Griffith University Gold Coast, Australia
      • • Short Talk: Specific Inhibition of NLRP3 in Chikungunya Disease Reveals a Role for Inflammasome in Alphavirus-Induced Inflammation
    • Kar Muthumani, Wistar Institute, USA
      • • Short Talk: Synthetic Nucleic Acid Antibody Prophylaxis + DNA Vaccine Confers Rapid and Durable Protective Immunity against Zika Virus
• 12:30—15:30 :   Networking Lunch /  Poster Session 1  /   Coffee Available  ( Lecture Hall LG 2 )
• 15:30—17:30 :   ZIKA Virus Countermeasures   ( Grand Hall )
  • • * Suresh Mahalingam, Griffith University, Australia
    • Raman Rao, Takeda Pharmaceutical Company, USA
      • • Talk Title to be Announced
    • Mauro Martins Teixeira, Universidade Federal de Minas Gerais, Brazil
      • • The Role of Glutamate Receptors in the Pathogenesis of Zika
    • Speaker to be Announced
    • Natalie A. Prow, University of South Australia, Australia
      • • Short Talk: A New Replication-Defective, Vaccinia-Derived, CHO-Manufactured, Vaccine Vector System (SCV) is Effective in Preclinical Studies against Zika and Chikungunya Viruses
    • Mingyuan Li, University of Hong Kong, Hong Kong
      • • Short Talk: Activated ADP-Ribosylation Factor 4 (ARF4) is Required for ZIKA Virus (ZIKV) Infectious Cycle

TUESDAY, OCTOBER 16

• 08:30—09:00 :   Poster Setup   ( Lecture Hall LG 2 )
• 09:00—17:00 :Poster Viewing   ( Lecture Hall LG 2 )
• 09:00—10:30 :   Ebola Virus: Biology and Host Interactions   ( Grand Hall )
  • • * [Erica Ollmann Saphire (born 1972)], The Scripps Research Institute, USA
    • Christopher F. Basler†, Georgia State University, USA
      • • Talk Title to be Announced
    • [Dr. Heinz Ulrich Feldmann (born 1959)], Rocky Mountain Laboratories, USA
      • • Animal Models of Ebolaviruses
    • Adam Joseph Hume†, Boston University, USA
      • • Short Talk: The Use of Minigenome Systems as Tools to “Fill in the Blanks” for Uncultured Emerging Viruses and Facilitate Virus Rescue: A Lloviu Virus Case Study
    • Beatriz Escudero Pérez, Bernhard Nocht Institute for Tropical Medicine, Germany
      • • Short Talk: Comparative Pathogenesis of Ebola and Reston Virus in Humanized Mice
    • Coffee Break
• 10:50—12:30 :   Ebola Virus: Vaccines and Therapeutics   ( Grand Hall )
  • • * [Dr. Heinz Ulrich Feldmann (born 1959)], Rocky Mountain Laboratories, USA
    • Ana Maria Henao-Restrepo, World Health Organization, Switzerland
      • • Talk Title to be Announced
    • [Erica Ollmann Saphire (born 1972)], The Scripps Research Institute, USA
      • • Structural Studies to Guide the Development of Broadly Reactive Antibodies against Ebolaviruses and Lassa Virus
    • John Misasi, NIH/NIAID/VRC, USA
      • • Short Talk: ChAd3-Based Ebola Vaccination Induces Protective Antibody Classes
    • [Sarah T.C. Elliott, Ph.D. (born 1983)]†, Wistar Institute, USA
      • • Short Talk: A Synthetic Micro-consensus DNA Vaccine Induces Potent Immune Responses Against Diverse Strains of Marburgvirus
• 12:30—15:00 :   Lunch   /   Poster Session 2   /   Coffee    ( Lecture Hall LG 2 )
• 15:00—17:00 :   Zoonotic Influenza and MERS   ( Grand Hall )
  • • * Andrew G. Bean, Commonwealth Scientific and Industrial Research Organization, Australia
    • Yi Guan, University of Hong Kong, Hong Kong
      • • Zoonotic Influenza Viruses from China, a Persistent Pandemic Threat?
    • KY Yuen, University of Hong Kong, Hong Kong
      • • Host Cellular Protein Facilitating Viral Replication
    • [Bartholomeus "Bart" Leonardus Haagmans (born 1963)], Erasmus MC, Netherlands
      • • MERS-Coronavirus: From Discovery to Intervention
    • Nicole Lai Giea Seng, University of Hong Kong, Hong Kong
      • • Short Talk: Virulence Determinants of Novel Influenza A (H7N9) Virus in Mammals
    • Sabiha Jahan Akhee†, University of Hong Kong, Hong Kong
      • • Short Talk: Deubiquitylase OTUB1 Plays Critical Role in Influenza A Virus Infection and Immune Response

WEDNESDAY, OCTOBER 17

• 09:00—12:30 :   MERS   ( Grand Hall )
  • • * John W. Lowenthal, Deakin University, Australia
    • [Dr. Joseph Sriyal Malik Peiris (born 1949), University of Hong Kong, Hong Kong
      • • Emerging Virus Disease at the Animal-Human Interface
    • [Dr. Ralph Steve Baric (born 1954)], University of North Carolina at Chapel Hill, USA
      • • Rapid Response Strategies to Control Emerging Coronavirus Infections
    • Dong-Yan Jin†, University of Hong Kong, Hong Kong
      • • Short Talk: Suppression of Type I Interferon Production by Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein through Interaction with HSP70 Chaperone
    • Lisa E. Gralinski, University of North Carolina, USA
      • • Short Talk: Using a Reduced Complexity Cross to Identify Host Susceptibility Factors to SARS-CoV Infection
    • Coffee Break
    • * [Bartholomeus "Bart" Leonardus Haagmans (born 1963)], Erasmus MC, Netherlands
    • John W. Lowenthal, Deakin University, Australia
      • • A Strategy for Developing a MERS Camel Vaccine in order to Protect Humans
    • Jincun Zhao, Guangzhou Institute of Respiratory Disease, China
      • • Immune Responses in MERS-CoV Infected Mice and Humans
    • Stalin Raj Victor, Indian Institute of Science Education and Research Thiruvananthapuram, India
      • • Short Talk: Chimeric Camel-Human Heavy Chain Antibodies Protect Mice from MERS-CoV Infection
    • Neeltje van Doremalen, NIH/NIAID, USA
      • • Short Talk: The Omics of Sex-Specific MERS-CoV Severity in a Transgenic Mouse Model
• 12:30—17:00 :   Poster Setup   /  On Own for Lunch and Recreation   /   Poster Viewing  /   Coffee Available   ( Lecture Hall LG 2 )
• 17:00—19:00 :   Emerging Disease Detection and Surveillance   ( Grand Hall )
  • • * Ana Maria Henao-Restrepo, World Health Organization, Switzerland
    • [Dr. Marion Petronella Gerarda Koopmans (born 1956)], Erasmus MC, Netherlands
      • • Challenges and Opportunities in Emerging Disease Detection
    • Gavin J.D. Smith, Duke-NUS Graduate Medical School, Singapore
      • • Surveillance for Risk Assessment and Prediction
    • [Dr. Lin-Fa Wang (born 1960)], Duke-NUS Medical School, Singapore
      • • From SARS to SADS: EIDs Caused by Bat Coronaviruses
    • Anna Uehara, Duke-NUS Medical School, Singapore
      • • Short Talk: Serologic Evidence of Bat Orthoreovirus in Singapore
    • Kenrie Pui Yan Hui, University of Hong Kong, Hong Kong
      • • Short Talk: Tropism and Pathogenesis of the Highly Pathogenic Avian Influenza A/H7N9 virus in ex vivo and in vitro Cultures of the Human Respiratory Tract
• [...]

THURSDAY, OCTOBER 18

• 09:00—12:30 :   Influenza: Immunity and Vaccines   ( Grand Hall )
  • • * Ralph A. Tripp, University of Georgia, USA
    • Leo Poon, University of Hong Kong, Hong Kong
      • • Universal Influenza Vaccines for Pandemic Response
    • Andrew G. Bean, Commonwealth Scientific and Industrial Research Organization, Australia
      • • Tailoring the Avian Host Immune Response for Enhanced Vaccine Production
    • Sophie A. Valkenburg†, University of Hong Kong, Hong Kong
      • • Short Talk: ADCC Antibodies are a Protective Immune Correlate in a Household Model of Influenza Transmission
    • [Li-Meng Yan], University of Hong Kong, Hong Kong
      • • Short Talk: Combined use of Live-Attenuated and Inactivated Influenza Vaccines to Enhance Heterosubtypic Protection
    • Coffee Break
    • * [Dr. Lin-Fa Wang (born 1960)], Duke-NUS Medical School, Singapore
    • Ted M. Ross, University of Georgia, USA
      • • Broadly Protective Influenza Vaccines: Protection Against Mismatched Strains
    • Mario Barro, Sanofi Pasteur, USA
      • • Talk Title to be Announced
    • Tomas Cihlar (born 1967) , Gilead Sciences, USA
      • • Short Talk: Broad Spectrum Antiviral Remdesivir for the Treatment of Emerging Viral Infections with High Outbreak Potential
• 12:30—13:30 :   Lunch   ( Lecture Hall LG 2 )
• 13:30—16:00 :   Vaccine and Therapeutic Strategies   ( Grand Hall )
  • • * [Dr. Marion Petronella Gerarda Koopmans (born 1956)], Erasmus MC, Netherlands
    • Stephen Whitehead, NIAID, National Institutes of Health, USA
      • • Evaluation of Live Attenuated Vaccines for Dengue and Zika Viruses (and their Challenge Models)
    • Ralph A. Tripp, University of Georgia, USA
      • • Novel Strategies to Improve Vaccine Yield
    • Coffee Break
    • Adam Taylor, Griffith University, Australia
      • • Short Talk: Novel Delivery of a Live-Attenuated Chikungunya Virus Vaccine Candidate
    • James Duehr, Icahn School of Medicine, USA
      • • Short Talk: Characterization of Humoral Immunity Generated against Andes Virus GnGc
    • Renu Khasa, Translational Health Science and Technology Institute, India
      • • Short Talk: RNA Interference Based Membrane Trafficking Screen Identifies Drug Targets for Japanese Encephalitis Virus
    • Danielle E. Anderson, Duke-NUS Medical School, Singapore
      • • Short Talk: SEC61B is a Cellular Host Factor Required for Mumps Virus Replication in Humans and Bats
• 16:00—16:30 :  Meeting Wrap-Up: Outcomes and Future Directions (Organizers)    ( Grand Hall )
• [...]

FRIDAY, OCTOBER 19

• Departure

NOTES

We gratefully acknowledge the generous grant for this conference provided by:

• National Institutes of Health  /  National Institute of Allergy and Infectious Diseases (NIAID)   Grant No. 1 R13 AI140574-01    [HITS Research note: Grant info available at https://grantome.com/grant/NIH/R13-AI140574-01 ]

  • • Funding for this conference was made possible (in part) by 1 R13 AI140574-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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