Dr. Bernhard Fleischer (born 1950)

Dr Bernhard Fleisher, from March 2018 article on "Yerevan State Medical University"[HE00A1][GDrive]

Wikipedia (DE) 🌐 Bernhard Fleischer

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ASSOCIATIONS (Events)

German wikipedia entry for "Bernhard Fleischer" (Feb 11, 2023)

Below is the Google-translate of the German wikipedia page    /  Saved source : [HK00B0][GDrive

Bernhard Fleischer (born December 25, 1950[1] in Leipzig) is a German physician, parasitologist and immunologist.

Fleischer studied medicine and received his doctorate in human medicine in 1977 at the University of Gießen under Hansjürgen Staudinger (See https://de.wikipedia.org/wiki/Hansj%C3%BCrgen_Staudinger ) .[2] He is a specialist in microbiology and infection epidemiology. In 1993 he became a professor for tropical medicine and immunology at the University of Hamburg. From 1993 he was head of department and from 1996 to 2007 director of the [Bernhard Nocht Institute for Tropical Medicine] (which has been managed by a foundation board since 2008), to whose board he then changed.[3] Until 2017, he was also director of the Institute for Immunology at the University Hospital Hamburg-Eppendorf. He declined calls to the Chair of Immunology at the University of Düsseldorf (1991), to the Chair of Medical Microbiology at the University of Marburg (1996) and to the Chair of Microbiology and Hygiene at the University of Cologne (1997).

In the late 1980s, he was one of the first to describe superantigens.

Bernhard Fleischer is a member of the Leopoldina (since 1995)[4] and a member of the Academy of Sciences in Hamburg. In 1983 he received the advancement award and in 1992 the award from the German Society for Hygiene and Microbiology, in 1986 the Arthur Pappenheim Prize[5] from the German Society for Hematology and Oncology (together with A. Rhagavachar), in 1990 the Science Prize for Basic Medical Research from the GSK Foundation,[5] in 1993 the Robert Koch Promotional Prize,[6] in 1997 the Aronson Prize[7] and in 2016 the Badge of Honor of the Danylo Halytsky National Medical University, Lviv, Ukraine. He is married and has three children. Since 2014 he has been secretary of the German Society for Tropical Medicine, Travel Medicine and Global Health e.V. (DTG).

Writings

Prabook.com profile entry for "Bernhard Fleischer: administrator, educator, medical scientist"

Saved source :  [HL009L][GDrive

Bernhard Fleischer, German medical facility administrator, educator, scientist. Diplomate in medical microbiology. Recipient Junior Scientist award German Society for Microbiology and Hygiene, 1983, Pappenheim prize German Society for Hematology, 1986, Medical Research award SmithKline Beecham Beecham Foundation, 1990, Promotional award Robert Koch Foundation, 1993, Aronson prize State of Berlin, 1997, others.

Background

Fleischer, Bernhard was born on December 25, 1950 in Leipzig, Germany.

Education

Doctor of Medicine, University giessen, Germany, 1977.

Career

Postdoctoral fellow, Institute for Virology/U. Giessen, 1977-1979; postdoctoral fellow, Institute for Virology and Immunobioogy/U. Würzburg, Germany, 1979-1983; assistant professor department medical microbiology and immunology, U. Ulm, Germany, 1983-1986; associate professor, U. Ulm, Germany, 1986-1987; associate professor 1st department medicine, U. Mainz, Germany, 1987-1993; professor, U. Hamburg, Germany, since 1993; department chairman medical microbiology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, since 1993; vice director, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, 1994-1996; director, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, since 1996. Member of advisory board German Institute for Medical State Examinations, since 1991.

Membership

Member American Association Immunologists, American Society for Microbiology, German Society Hygiene and Microbiology (advisory board since 1994), German Society for Immunology (advisory board), Academy of Sciences of 1794 (Erfurt), German Academy of Sciences Leopoldina.

Connections

Married Sabine Fleischer. Children: Lennart, Henrike, Wiebke.

Education

Career

2018 (March 19) - "Bernhard Fleischer Visiting Professor in the Department of Medical Genetics at Yerevan State Medical University"

Saved PDF : [HE009Z][GDrive]  

 [HE00A0][GDrive

Since November 30, 2017 Bernhard Fleischer, Professor at Bernhard Nocht Institute, has become Visiting Professor of Medical Genetics at Yerevan State Medical University.

Bernhard Fleischer is a German physician, parasitologist and immunologist. He received his medical education at the Universities of Giessen and Hamburg. In 1993 he became professor of tropical medicine and immunology at the University of Hamburg then he became Director of the Institute of Immunology at the University Medical Center Hamburg-Eppendorf.

During different periods of professional career, Professor Fleischer worked in some of the most popular and top-ranking universities in Germany and directed [Bernhard Nocht Institute for Tropical Medicine], Hamburg.

Bernhard Fleischer is a member of the Leopoldina (since 1995) and a member of the Academy of Sciences in Hamburg. In 1992 he was awarded the prize of the German Society for Hygiene and Microbiology, and in 1997 he was awarded the Aronson Prize.

The Professor participated in numerous international conferences and his articles were published in the world’s most famous journals.

https://www.leopoldina.org/fileadmin/redaktion/Mitglieder/CV_Fleischer_Bernhard_D.pdf

Curriculum Vitae Prof. Dr. med. Bernhard Fleischer Name:  Geboren: Bernhard Fleischer 25. Dezember 1950 Forschungsschwerpunkte: Superantigene, Lymphozyten, Immunabwehr, tropische Infektionserreger, Epidemiologie Bernhard Fleischer ist ein deutscher Mediziner, Parasitologe und Immunologe. Er ist Leiter des Nationalen Referenzzentrums für tropische Infektionserreger am Bernhard‐Nocht‐Institut in Hamburg. Seine Schwerpunkte liegen in der zellulären Immunologie und medizinischen Mikrobiologie mit besonderem Fokus auf sogenannte Superantigene, die er Ende der 1980er Jahre als einer der Ersten beschrieb. Akademischer und beruflicher Werdegang  seit 2008 seit 2002 seit 2002 1996 ‐ 2007 seit 1993 1990  1987  1986  1985  1977  Mitglied im Vorstand des Bernhard‐Nocht Instituts für Tropenmedizin und Leitung der Sektion Immunologie Direktor des Instituts für Immunologie am Universitätsklinikum Hamburg‐Eppendorf Leitung des Nationalen Referenzzentrums für tropische Infektionserreger am  Bernhard‐Nocht‐Institut in Hamburg Direktor des Bernhard‐Nocht‐Instituts für Tropenmedizin in Hamburg  Professor für Tropenmedizin und Immunologie an der Universität Hamburg Facharzt für Mikrobiologie und Infektionsepidemiologie Professur an der Universität Mainz Professur an der Universität Ulm Habilitation an der Universität Gießen  Promotion an der Universität Gießen  

1970 ‐ 76 Studium  der Humanmedizin an den Universitäten Hamburg und Gießen Funktionen in wissenschaftlichen Gesellschaften und Gremien 2012 ‐ 14 Vorsitzender und seit 2005 Mitglied des Auswahlausschusses zur Vergabe  von Georg Forster‐Forschungspreisen und ‐stipendien der Alexander‐von‐ Humboldt‐Stiftung Kuratoriums‐Mitglied der Werner‐Otto‐Stiftung Projektkoordination, Mitgliedschaft in Verbundprojekten 2006 ‐ 2009 2004 ‐ 2018 1996 ‐ 2000 1979 ‐ 2004 Leiter des DFG SFB 470 Teilprojekts „Molekulare Interaktion von Siglecs mit sialylierten Liganden auf Trypanosoma cruzi und deren Bedeutung für die Regulation der Immunabwehr (C11)“ Antragsteller des DFG‐Projekts „Analyse der regulatorischen Funktion von CD83 auf B‐Lymphozyten“ Antragsteller des DFG‐ Schwerpunktprogramms „Induktion und Aufrechterhaltung der Wirt‐Zell‐Proliferation durch die intrazellulären Parasiten Theileria annulata und Theileria parva“ Leiter des DFG SFB 545 Teilprojekts „Alternative Aktivierung von T‐Lymphozyten (B 8)“ Auszeichnungen und verliehene Mitgliedschaften seit 2009 1997   seit 1995  1993   seit 1992 1992  1990  1990 1986  Mitglied der Akademie der Wissenschaften in Hamburg Aronson‐Preis des Landes Berlin für herausragende Leistungen in der Mikrobiologie und Immunologie Mitglied der Nationalen Akademie der Wissenschaften Leopoldina  Robert Koch‐Förderpreis der Universität Clausthal‐Zellerfeld  Auswärtiges Mitglied der Akademie gemeinnütziger Wissenschaften zu Erfurt von 1754 Hauptpreis der Deutschen Gesellschaft für Hygiene und Mikrobiologie Preisträger „Medizinische Grundlagenforschung“ der GlaxoSmithKline Stiftung Wissenschaftspreis für Medizinische Grundlagenforschung der Stiftung Knochenmark‐ und Stammzellspende Deutschland Arthur Pappenheim‐Preis der Deutschen Gesellschaft für Hämatologie und Onkologie


Bernhard Fleischer hat sich durch Entdeckungen auf dem Gebiet der zellulären Immunologie ausgezeichnet. Einer seiner wichtigsten Beiträge war die Aufklärung des Wirkungsmechanismus der so genannten Superantigene Ende der 1980er Jahre. Diese hauptsächlich von Bakterien gebildeten Moleküle wirken toxisch auf unser Immunsystem und werden mit einer Reihe tödlicher Krankheiten wie dem toxischen Schocksyndrom mit nachfolgendem Multiorganversagen und diversen Lebensmittelvergiftungen in Verbindung gebracht. Der Name „Super‐Antigene“ beschreibt die Eigenschaft der Moleküle, wie Antigene eine Immunreaktion auszulösen. Dabei reichen schon wenige Moleküle aus, um eine „super“starke  Stimulation derjenigen weißen Blutzellen auszulösen, die für die erworbene Immunantwort zuständig sind, die so genannten T‐Lymphozyten oder kurz T‐Zellen. Auch der Analyse der Funktion und Spezifität dieser T‐Lymphozyten bei Infektionen und Autoimmunerkrankungen widmete sich Fleischer in seinen Forschungen, ebenso wie der  Beschreibung neuer Signalwege in T‐Lymphozyten und der Immunantwort gegen tropische Parasiten.  

2000 (September) - "100 years of tropical medicine in Hamburg at the Bernhard Nocht Institute", written by Bernhard Fleischer 

Saved PDF : [HP00D7][GDrive

The Bernhard Nocht Institute (BNI) is a four months younger and much smaller sibling of the Instituto Oswaldo Cruz. It was founded on 1 October 1900 as an Institut für Schiffs- und Tropenkrankheiten (Institute for Maritime and Tropical Diseases) and was later named after its founder and first director Bernhard Nocht. Today it is the Germany’s largest institution for research in tropical medicine. It is a government institution affiliated to the Federal Ministry of Health of Germany and the Department of Health of the State of Hamburg. As the center for research in tropical medicine in Germany the BNI is dedicated to research, training and patient care in the area of human infectious diseases, which are of particular relevance in the tropics. It is the primary mission of the BNI to develop means to the control of these diseases. Secondary missions are to provide expertise for regional and national authorities and to directly and indirectly improve the health care for national and regional citizens in regard to diseases of the tropics. 

For full article, See :   Bernhard Nocht Institute for Tropical Medicine  

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2003 (March 27) - The Bismarck Tribune : Includes mention of"Bernhard Nocht" 

Note : Director of Bernhard Nocht Institute is Dr. Bernhard Fleischer (born 1950)   

Full newspaper page : [HN029K][GDrive]  /  Clip above : [HN029L][GDrive

https://pubmed.ncbi.nlm.nih.gov/12682141/  


https://journals.asm.org/doi/10.1128/JCM.41.4.1529-1535.2003 


Article : 

HISTORY

Received: 11 October 2002

Revision received: 31 December 2002

Accepted: 13 January 2003

Published online: 1 April 2003


J Clin Microbiol

. 2003 Apr;41(4):1529-35. doi: 10.1128/JCM.41.4.1529-1535.2003.

Detection, differentiation, and quantitation of pathogenic leishmania organisms by a fluorescence resonance energy transfer-based real-time PCR assay

Alexandra Schulz 1, Katja Mellenthin, Gabriele Schönian, Bernhard Fleischer, Christian Drosten

Affiliations expand

Free PMC article

Abstract

Real-time technology eliminates many of the pitfalls of diagnostic PCR, but this method has not been applied to differentiation of Leishmania organisms so far. We have developed a real-time PCR that simultaneously detects, quantitates, and categorizes Leishmania organisms into three relevant groups causing distinct clinical pictures. The analytical sensitivity (detection rate of >or=95% at 94.1 parasites/ml of blood) was within a range that has been determined previously to facilitate the confirmation of visceral leishmaniasis from peripheral blood. Parasites were successfully detected in 12 different clinical samples (blood, bone marrow, skin, and liver). The Leishmania donovani complex, the Leishmania brasiliensis complex, and species other than these could be clearly discriminated by means of distinct melting temperatures obtained with fluorescence resonance energy transfer probes (melting points, 72.7, 67.1, and 65.0 degrees C, respectively). All three groups could be quantified within equal ranges. As in other real-time PCRs, the variability in the quantification of DNA was small (coefficient of variation [CV], <2%). However, human samples containing low levels of parasites (100 parasites per ml of blood) showed higher variation (CV, 60.89%). Therefore, despite its superior analytical performance, care must be taken when real-time PCR is utilized for therapy monitoring.


Acknowledgments

We are grateful to Patty Wilkins, Gisela Bretzel, and Joachim Clos for providing cultured Leishmania parasites and to Nadine Petersen, Britta Liedigk, and Anne McDonald for excellent technical assistance. We thank Stephan Günther for critical reading of the manuscript.

This work was supported by the German Ministry of Health as part of funding of the National Reference Center for Tropical Infections.


2003 (April 13) - The Fort Collins Coloradoan : "SARS Outbreak - German Institute professor leads search for vaccine to stop disease"

Clip saved as PDF with OCR :  [HN029O][GDrive]    /   Allso see - 2002-2004 SARS outbreak   /  Dr. Bernhard Fleischer (born 1950) /

Full newspaper page : [HN029M][GDrive] /   Clip aboe : [HN029N][GDrive

Editor's note: At the end of March [2003], only two months after we learned about the outbreak of severe acute respiratory syndrome, or SARS, in southern China, professor [Dr. Bernhard Fleischer (born 1950)] of the [Bernhard Nocht Institute for Tropical Medicine] in Hamburg, Germany, discovered a virus believed to be responsible for causing the disease. Eliza Sarnacka-Mahoney, a freelance journalist from Fort Collins, talked with Fleischer last week. Following are excerpts from that interview.

Shope / Denison / Drosten

https://www.newspapers.com/image/860720799/?terms=sars%20bernhard&match=1

https://www.newspapers.com/image/583674573/?terms=sars%20bernhard&match=1

The Santa Fe New Mexican

18 Apr 2003, Fri · Page 17