Research

Our lab is broadly interested in the development of new chemical tools to support biological research. Our research leverages organic synthesis and rational chemical design to create new biological probes (bio-probes) that enable selective targeting of biological macromolecules from complex cellular environments. 

In particular, we are interested in generating libraries of compounds comprising electrophilic moieties through diversity-oriented synthesis. We are working to tune these probes to target enzymes involved in bacterial glycosylation. 

We also investigate new synthetic strategies for making complex bacterial sugars.