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Field:
Nanomedicine harnesses nanoscale materials to improve the diagnosis, delivery, and treatment of diseases. By tailoring physicochemical properties (size, charge, surface chemistry), nanoparticles can cross biological barriers, selectively accumulate in diseased tissues, and release therapeutic cargos in a controlled manner.
Our Approach:
Our lab develops inorganic and hybrid nanotherapeutics that address diverse biomedical challenges. We focus on designing nanoparticles not only as delivery carriers, but also as active therapeutic agents (e.g., nanozymes) or theranostic platforms that integrate imaging and therapy. By leveraging bio-inspired conjugates, enzyme-mimicking nanomaterials, and physical energy–responsive nanoparticles, we extend nanomedicine applications to cancer, inflammation, and regenerative medicine.
Representative Works:
Water molecular-heating nanoparticles enabling NIR-guided photothermal therapy of glioblastoma
(Nature Communications 2023).
Aurozyme, a gold nanozyme with switchable peroxidase-to-catalase activity for colitis therapy (Small 2023).
Orally absorbable gold nanoparticles for brain tumor phototherapy (Bioactive Materials 2022)
DAMP-modulating nanoparticles for immunomodulation in cell transplantation (Biomaterials 2022)
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