Maitland-van der Zee was educated as a pharmacist, clinical pharmacologist and epidemiologist. She obtained her PhD at Utrecht University in 2003, and worked as a postdoc in the Human Genetics Center, University of Texas, Houston Tx, USA from 2003-2005. From 2005-2016 she worked at the division of Pharmacoepidemiology and Clinical Pharmacology of Utrecht University first as an assistant-Professor and later as an associate-Professor of Personalized Medicine. In 2016 she became a full professor of Precision Medicine in Respiratory disease at the Academic Medical Center (AMC) in Amsterdam. She is also head of the research group at the Respiratory Medicine department and of the Pediatric Respiratory Medicine and Allergy department in the AMC. Her current research focusses on patient-, environmental characteristics and molecular biomarkers (genome, epigenome, transcriptome, microbiome, metabolome) that can predict the optimal treatment for the individual patient with respiratory disease. Maitland-van der Zee is the PI of several large (international) studies. She is the vice-president of the European Association of Systems Medicine (EASYM), the president of the Federation Innovative Drug Research in the Netherlands (FIGON), she is secretary/treasurer of the Netherlands Society of Clinical Pharmacology and Biopharmacy (NVKFB) and the president of the Netherlands Respiratory Society (NRS). She has published >200 peer reviewed articles, she delivered 13 PhD fellows and 17 are currently working under her supervision. She obtained many research grants from governmental, charity and industrial funds.