Tahiyana Khan

Tahiyana graduated with her BS in neuroscience from Temple University, where she examined glial dysfunction in a neonatal mouse model of cerebral palsy in Dr. Tanya Ferguson’s lab. Following graduation in 2015, Tahi joined the laboratory of Drs. Virginia Lee and John Trojanowski at the University of Pennsylvania, investigating TDP-43 proteinopathy in motor neuron (MN) disease. Specifically, she examined the role of aging on accelerated MN disease progression, microglia mediated recovery from MN degeneration, and the involvement of matrix metalloproteinase 9 (MMP9) in the exacerbation of MN death, resulting in three co-author publications. Her interest in aging and cellular mechanisms of neurodegeneration influenced Tahi to pursue her Ph.D. in neuroscience at Georgetown University in July 2018. Currently, Tahi is exploring the role of cellular senescence in status epilepticus in Dr. Forcelli’s lab.

Published manuscript from the lab:

Sepulveda-Rodriguez A, Li P, Khan T, Ma JD, Carlone CA, Bozzelli PL, Conant KE, Forcelli PA, Vicini S. Electroconvulsive Shock Enhances Responsive Motility and Purinergic Currents in Microglia in the Mouse Hippocampus. eNeuro. 2019 Apr 23;6(2). pii: ENEURO.0056-19.2019. doi: 10.1523/ENEURO.0056-19.2019. eCollection 2019 Mar-Apr. PubMed PMID: 31058213; PubMed Central PMCID: PMC6498419.