Facilities

Institutional Environment:

 The Department of Materials Science and Engineering at National Taiwan University of Science and Technology (MSE@NTUST) has demonstrated a long-standing excellence in the fields of biomedical materials, bioelectronic interfaces, and device research. In those fields, MSE@NTUST has committed to remain one of the world leaders in research under the high-level goals of the collaboration among Academia Sinica (AS), Taipei Medical University, Tri-Service General Hospital, Shin Kong Wu Ho-Su Memorial Hospital (SKW), National Taiwan University Cancer Center (NTUCC), and other Departments within the College of Applied Sciences such as Graduate Institute of Biomedical Engineering and Applied Science and Technology. MSE@NTUST has also housed dozens of laboratories and numerous meeting and seminar rooms (E1 building), bringing together the materials, nanofabrication, organic electronics, and biomedical communities under high collaboration. This atmosphere is the ideal setting for our proposed research fields.

Lab Space and Instruments:

• Independent Lab (Prof. Yu-Sheng Hsiao): 

[Materials & Device Fabrication]

1. Microwave Synthesizer (CEM Corporation, Discover 2.0)

2. Circulating Water Aspirator and Filtration Systems (Sibata Scientific Technology, WJ-15)

3. Probe-type Sonicator (QSonica LLC., Q700) & Water Bath Ultrasonic Cleaner (Elma)

4. Homogenizer (Prema, IADI-HG-300D, Max. RPM 26,000 rpm, 0.3 mL~3 L)

5. High-speed Centrifuge (Gyrozen, 1580R, Max. RPM 15,000 rpm)

6. Multi-Parameter Meter (HACH, HQ430D) with pH Electrode and Dissolved Oxygen Sensor

7. Chemical Hood (MIT) & Spin Coator (O-LINK)

8. Laboratory Hot-plate 1 (Corning)

9. Laboratory Hot-plate 2 (SH Scientific)

10. Vacuum Oven (France Etuves, XFL-020)

11. CO2 Laser Machining System (Universal Laser Systems Inc., VLS2.3)

12. UV Mask Aligner (SWIN, MA4)

13. Precision Glass Scriber (SWIN, GS470)

14. Plasma Cleaner (Harrick Plasma Corp., PDC-32G, Low/6W; Medium/12W; High/18W)

15. Rotational Viscometer (Anton Paar, ViscoQC 300R)

16. UV Cure Chamber 1 (Electro-Lite Corporation, ELC-500, 30 mW/cm2 @ 365 nm)

17. UV Cure Chamber 2 (OPAS-XLite 500, 50-70 mW/cm2 @ 254 nm/365 nm)

18. Freeze Dryer (EYELA, FDU-1110)

19. Automatic Doctor Blade Coater (TQCSHEEN, AB4120) with Universal Applicator (0-3000 um, ZEHNTNER)

20. Electrospinng System (Homemade with Sheath & Core spinneret)

21. Hot-press System (MIT)

22. Glove Box System (MIT)

23. Thermal Evaporation System (MIT)

  [Optical & Electrical System & Characterization] 

1. Solar Simulator (Enlitech, ALS-300, 300W) with AM 1.5G filter

2. Reference Solar Cells and Meter (Newport)

3. Multi-wavelength Fiber-Coupled LED source (Mightex, Inc.; 385, 470, 505, 530, 590, 625, 740, and 850 nm)

4. Micro Spectrometer (OtO Photonics, Model SE2020-025-VNIR, 305-1020 nm)

5. Four-point Probe (Keithley 2400 SourceMeter with home-made stage)

6. Source Measurement Unit (Keysight B1500A and Agilent B2912A) and Probe Station

7. Switching Matrix (Agilent E5250A)

8. Potentiostat/galvanostat Electrochemical Analyzer (Metrohm, Autolab PGSTAT302N)

9. Digital Oscilloscope with Arbitrary Function Generator (Tektronix Tech., MDO34, 200 MHz, 2.5Gs/s)

10. Electrokinetic Analyzer (Anton Paar, SurPASS 3)

11. Thermal Imaging Camera (FLIR Systems Inc.)

12. Cross-Cut Tester (ZCC 2087.5, ZEHNTNER)

13. Elite Controller and EDC Source Measure Unit X2 (SMU, BioPro Scientific)

14. Tensile-compression Testing System (JSV-H1000,  JISC Ltd.) with ALGOL force gauge (HF-100 & HF-10)

• [Cell Culture Room] 

1. Wet & Dry bath incubator (Major Science)

2. Ultrapure water purification system 1 (AVIDITY, DUO Type 1+Type 2)

3. Simplicity®water purification system 2 (Type I, Millipore-Merck)

4. Biosafety Cabinet (Thermo Scientific, 1300 series A2)

5. Cell Incubator (Thermo Scientific, Thermo 370)

6. Digital Incubator (for the chorioallantoic membrane (CAM) assay)

7. Clinical Centrifuge (Hanil Scientific, Fleta 5, Max. RPM 5,500 rpm)

8. Inverted Fluorescence Microscope (Olympus, CKX 41) with Mercury Lamphouse & B/G Filters

9. High Content Imaging System (Logos Biosystems, CELENA®X, DAPI_Ex375, EGFP_Ex470, RFP_Ex530)

10.  Automated Cell Counter (Logo Biosystems, LUNA)

11. Electric Cell-substrate Impedance Sensing System (Applied Biophysics)

12. 3D Cell Culture System by Magnetic Levitation (Greiner Bio-One, n3D Biosciences)

13. Spectrophotometer (Thermo Scientific, NanoDrop 2000c)

14. Constant Current Stimulator with Pulse Generator (Digitimer, DS3 & DG2A)

15. Vertical Autoclave (ZEALWAY, MODEL: FD50R)

16. Cryogenic Vial Auto Sealer (HOTECH, Model 516)

17. Peristaltic Pump x3 (Longer, BT300LJ)

18. Syringe Pump (KD Scientific, model 210)

19. Automated Programmable Dual Syringe Pump System (Mitos Duo XS-Pump, Dolomite)

20. Automatic Exosome Isolation System (iZON Science, AFC-V2).

Cell Bank:

1. Leukemia: THP1, HL-60, K-562, Jurkat, RPMI-8226, Raji, Kasumi-1.

2. Lung cancer: H1975, H1650, A549. 

3. Bladder carcinoma: 5637, T24.

4. GBM cell line: DBTRG-05MG, GBM8401, GBM8901, G5T/VGH.

5. Breast cancer: MFA-MB-231, SK-BR-3, MCF7, BCM-1, T47D.

6. Liver cancer: HepG2, Mahlavu, J5.

7. Colon cancer: HT-29, HCT-116, HCT-8. 

8. Oral cancer: KB, SCC-4, SCC-5, OEC-M1, SAS.

9. Stomach cancer: AGS, SNU-16, NCI-N87.

10. Pacreatic cancer: PANC-1, AsPC-1.

11. Esophageal cancer: CE48T/VGH, CE81T/VGH.

12. Fibrosarcoma: HT1080.

13. Cervical cancer: HeLa, Ca Ski.

14. Prostate cancer: LNCaP, PC3, DU145.

15. Cardiac cell line: H9c2.

16. Normal cell: HaCat, ARPE-19.