E-learning is one of the most important trends in educational research and practice in the last decade. The Center will focus on the interactivity of the e-learning environment as the main axis of research. Interactivity is an important key to the success of e-learning. In an e-learning environment, interactivity includes a wide range of aspects, including human-computer interaction, peer interaction, and teacher-student interaction. These interactions encompass many learning theories and concepts, such as attention, cognitive processes, problem solving, and social interactions. The Center will attempt to explore the research issues related to the interactivity of e-learning from different theoretical perspectives and at different levels. In the field of empirical evidence on interactivity, the Center features two core axes: mobile learning and gamification/game-based learning. Through academic excellence, industry-academia cooperation, commercialization of educational games, large-scale educational field promotion and counseling, and international cooperation, NTUST is expected to become an international research center for this topic.