功能性核酸之智慧檢測技術
我們致力於開發新型核酸奈米生物技術，利用核酸分子的智慧辨識、基因編輯以及類酵素催化等功能，發展可應用於醫學檢測與疾病診療等相關精準醫學領域的新型生物智慧檢測技術。利用訊號放大策略的高敏度癌症標記物檢測方法的設計開發。
Functional nucleic acids
Compared with antibody-based immunoassays, functional nucleic acid platforms are alternative designs for molecular analysis. Thus, we are interested in the exploration of these nucleic acid molecules as novel analytical tools for chemical sensing, biomolecular detection, and nanotechnology.
奈米材料的生物醫學感測應用
通過對於材料與生物探針間的介面和分子間作用力的設計，達到對小分子或者生物標記物(biomarker)的便捷式檢測。
Nanosensing
Gold nanoparticls (AuNPs) are attractive because they provide unique size and distance-dependent SPR properties. The aggregation of AuNPs leads to a huge absorption band shift and color change from red to blue because of interparticle plasmon coupling. This color change allows AuNPs to be used for biosensing and biomedical applications. Therefore, our research focuses on the application of AuNPs as smart molecular probe for diagnostics and biosensing.
