422. Khaleel, Zinah Hilal;+ No, Young Hyun;+ Kim, Nam Hyeong;+ Bae, Do Hyun; Wu, Yibing; Kim, Suhyeon; Choi, Hojae; Lee, Da Eun; Jeong, Se Yun; Ko, Yoon-Joo; Kim, Seong-Gi; Suh, Minah; Kim, Jin-Chul;* DeGrado, William F.;* Kim, Ki Hyun;* Kim, Yong Ho.* Design of a Light and Ca2+ Switchable Organic-Peptide Hybrid. Proc. Natl. Acad. Sci. U.S. A. 2025, in press.
421. Lee, Yoonsuk;† Lee, Yun Young;† Park, Jinyoung;† Anna, Maksakova; Seo, Donghyuk; Kim, Jisun; Yeom, Ji Eun; Kim, Yewon; Kim, Cheol-Hwi; Ryoo, Rhim; Kim, Se-Na; Park, Juwon; Park, Wooram; Kim, Tae-Hyung; Choy, Young Bin; Park, Chun Gwon;* Kim, Ki Hyun;* Lee, Wonhwa.* Illudin S Inhibits p53-Mdm2 Interaction for Anticancer Efficacy in Colorectal Cancer. Biomed. Pharmacother. 2025, 182, 117795.
420. Huo, Chen; Baek, Jihye; Kim, Ki Hyun.* Antiviral potential of ginseng: Targeting human pathogenic viruses with compounds derived from ginseng. J. Ginseng Res. 2025, in press.
419. Arezoumand, Elham; Bagheri, Khadijeh; Mazloum, Sahand; Noh, Gang Min; Hamishehkar, Hamed;* Kosari-Nasab, Morteza;* Kim, Ki Hyun.* β-Cyclodextrin as an elicitor of polyphenolic contents of barley (Hurdeum vulgare) callus with antioxidant and anti-aging properties on human skin fibroblast cells (HFF2). Carbohydr. Polym. Technol. Appl. 2025, in press.
418. Jang, Yoon Seo; Kang, Dong-Min; Ko, Yoon-Joo; Ra, Moon-Jin; Jung, Sang-Mi; Ahn, Mi-Jeong; Lee, Seulah;* Kim, Ki Hyun.* Discovery of Isograndidentatin D, a Novel Phenolic Glycoside, and Anti-Helicobacter pylori Phenolics from Salix koreensis Twigs. Plants 2024, 13, 3603.
417. Gil, Tae-Young; Kim, Hyo-Jung; Kim, Hye-Min; Sim, Ha-Yeon; Choi, Woolim; Lee, Bum Soo; Kim, Ki Hyun; An, Hyo-Jin.* Aster glehni Ethanol Extract Inhibits Inflammatory Responses Regulating Skin Barrier Molecules in Human Keratinocytes. Nat. Prod. Sci. 2024, in press.
416. Cho, Yeo Rang; Hong, Joo-Hyun; Kang, Dong-Min; Ko, Yoon-Joo; Ahn, Mi-Jeong;* Kim, Ki Hyun.* Deodeokaloid, a New Indole Alkaloid N-Glycoside and Bioactive Phenolic Compounds from the Roots of Codonopsis lanceolata. Plants 2024, 13, 3243.
415. Glick, Virginia;1 Webber, Cecilia;1 Simmons, Lauren; Martin, Morgan; Ahmad, Maryam; Kim, Cecilia; Adams, Amanda; Bang, Sunghee; Chao, Michael; Howard, Nicole; Fortune, Sarah; Beura, Lalit; James, Michael J.; Lee, Seo Yoon; Mitchell, Caroline M.; Clardy, Jon; Kim, Ki Hyun;* Gopinath, Smita.* Vaginal lactobacilli produce anti-inflammatory b-carboline compounds. Cell Host Microbe 2024, 32, 1897–1909.
414. Yadav, Ram Prabodh;† Huo, Chen;† Budhathoki, Rabin; Budthapa, Padamlal; Bhattarai, Bibek Raj; Rana, Monika; Kim, Ki Hyun;* Parajuli, Niranjan.* Antibacterial, Antifungal, and Cytotoxic Effects of Endophytic Streptomyces Species Isolated from the Himalayan Regions of Nepal and Their Metabolite Study. Biomedicines 2024, 12, 2192.
413. Kim, Jisun;† Lee, Yoonsuk;† Kim, Jungbum; Park, Chai Won; Song, Hyeonhui; Hong, Jinkee; Lee, Sangmin; Jung, Won Hee; Hong, Joo-Hyun; Kim, Ki Hyun;* Lee, Wonhwa.* Conductive Bio-Harvesting Tonic (CBT) with an Anti-Dandruff Effect Enhances Hair Growth by Utilizing Naturally Generated Electric Energy during Human Activities. J. Microbiol. Biotechnol. 2024, 34,2376–2384.
412. Asadollahi, Leila; Abbaspour-Ravasjani, Soheil; Kim, Kyung Ah; Maghsoodi, Maryam; Hamishehkar, Hamed;*,† Kosari-Nasab, Morteza;† Kim, Ki Hyun.*,† Rice (Oryza sativa) Stem Cell as a Novel Promising Active Ingredient in Anti-proliferative Effects for Potential Skin Cancer Prevention and Skin Whitening Activity. Foods 2024, 13, 2803.
411. Chae, Si Hyeon; Cho, Chan Hee; Kim, Seon Hee; Kim, Ki Hyun.* Phenolic Compounds Isolated from Thlaspi arvense and their Effects on Osteoblast Differentiation in the Mouse Mesenchymal Stem Cell Line C3H10T1/2. Drug Targets and Therapeutics 2024, 3, 95-104.
410. Lee, Hak-Dong; Kim, Ji Hyun; Choi, Jong Hee; Kim, Ki Hyun; Ku, Jajung; Choi, Kyung; Kim, Hyun Young; Lee, Sanghyun;* Cho, Ik-Hyun.* Exploring phytochemicals and pharmacological properties of Populus × tomentiglandulosa. Front. Pharmacol. 2024, 15, 1406623.
409. Ahn, Si-young;1 Kim, Kyung Ah;1 Lee, Sullim;* Kim, Ki Hyun.* Potential skin anti-aging effects of main phenolic compounds, tremulacin and tremuloidin from Salix chaenomeloides leaves on TNF-α-stimulated human dermal fibroblasts. Chem. Biol. Interact. 2024, 402, 111192.
408. Kim, Minji;1 Park, Sangbin;1 Kang, Gyumin;1 Jang, Yoon Seo;1 Kim, Ki Hyun;* Han, Sunkyu;* Kim, Chung Sub.* Natural product anticipation via chemical synthesis: Discovery of two new securinega alkaloids. iScience 2024, 27, 110495.
407. Cho, Chan Hee; Chae, Si Hyeon; Kim, Seon Hee; Kim, Ki Hyun.* Phenolic Compounds Isolated from Juncus decipiens and Their Effects on Osteoblast Differentiation in the Mouse Mesenchymal Stem Cell Line C3H10T1/2. Nat. Prod. Sci. 2024, 30, 135-142.
406. Lee, Ju Ryeong; Hwang, Su Jung; Choi, Yukyung; Kim, Jonghwan; Lee, Gyu Sung; Lee, Bum Soo; Kim, Ki Hyun; Kang, Kyo Bin; Lee, Hyo-Jong; Kim, Chung Sub.* Structural Diversification of Pyrazinone Metabolites via Spontaneous oxa-Michael Addition in Staphylococcus xylosus. J. Nat. Prod. 2024, 87, 1881-1887.
405. Lee, Dahae;1 Lee, Seo Yoon;1 Ra, Moon-Jin; Jung, Sang-Mi; Yu, Jeong-Nam; Kang, Ki Sung;* Kim, Ki Hyun.* Cancer therapeutic potential of hovetrichoside C from Jatropha podagrica on apoptosis of MDA-MB-231 human breast cancer cells. Food Chem. Toxicol. 2024, 190, 114794.
404. Lee, Seoung Rak;† Dayras, Marie;† Fricke, Janis; Guo, Huijuan; Balluff, Sven; Schalk, Felix; Yu, Jae Sik; Jeong, Se Yun; Morgenstern, Bernd; Slippers, Bernard; Beemelmanns, Christine;* Kim, Ki Hyun.* Molecular networking and computational NMR analyses uncover six polyketide-terpene hybrids from termite-associated Xylaria isolates. Commun. Chem. 2024, 7, 129.
403. Keem, Min-Ji;1 Jo, Beom-Geun;1 Lee, Sang Heon;1 Kim, Tae-Young; Jung, Young Suk; Jeong, Eun-Ju; Kim, Ki Hyun;* Kim, Su-Nam;* Yang, Min Hye.* Ameliorative effects of Wikstroemia trichotoma 95% EtOH extract on a mouse model of DNCB-induced atopic dermatitis. J. Ethnopharmacol. 2024,333, 118398.
402. Ebrahimi, Alireza;† Andishmand, Hashem;† Huo, Chen;† Amjadi, Sajed; Khezri, Sima; Hamishehkar, Hamed; Mahmoudzadeh, Maryam;* Kim, Ki Hyun.* Glycomacropeptide: a comprehensive understanding of its major biological characteristics and purification methodologies. Compr. Rev. Food. Sci. Food Saf. 2024,23, e13370.
401. Thapa, Bijaya Bahadur;† Huo, Chen;† Budhathoki, Rabin;Chaudhary, Pratiksha; Joshi, Soniya; Poudel, Purna Bahadur; Magar, Rubin Thapa; Parajuli, Niranjan; Kim, Ki Hyun;* Sohng, Jae Kyung.* Metabolic Comparison and Molecular Networking of Antimicrobials in Streptomyces Species. Int. J. Mol. Sci. 2024,25, 4193.
400. Kim, Kyung Ah;† Tran, Nguyen Khoi Song;† Baek, Jiwon; Lee, Soah; Kang, Ki Sung;* Kim, Ki Hyun.* Proanthocyanidins and Phenolic Compounds from the Twigs of Salix chaenomeloides and Their Anti-Lipogenic Effects on 3T3-L1 Preadipocytes. Nutrients 2024, 16, 1036.
399. Rahmat, Endang;1 Yu, Jae Sik;1 Lee, Bum Soo; Lee, Jiyoung; Ban, Yeongjun; Yim, Nam-Hui; Park, Jeong Hwan; Kang, Chang Ho; Kim, Ki Hyun;* Kang, Youngmin.* Secondary metabolites and transcriptomic analysis of novel pulcherrimin producer Metschnikowia persimmonesis KIOM G15050: A potent and safe food biocontrol agent. Heliyon 2024, 10, e28464.
398. Lee, Da Yeong; Kim, Jonghwan; Lee, Gyu Sung; Park, Sehwan; Song, Jeongwon; Lee, Bum Soo; Lee, Seung Rak; Kim, Ki Hyun; Kim, Chung Sub.* Characterization of chemical interactions between clinical drugs and the oral bacterium, Corynebacterium matruchotii, via bioactivity-HiTES. ACS Chem. Biol. 2024, 19, 973-980.
397. Lee, Bum Soo;† Kim, Hoon;† Baek, Jiwon; Ryoo, Rhim; Lee, Seoung Rak;* Kim, Ki Hyun.* Determination of the Absolute Configuration of Secondary Alcohols in a Compound Mixture via the Application of Competing Enantioselective Acylation Coupled with LC/MS Analysis. Pharmaceutics 2024, 16, 364.
396. Kim, Kyung Ah; Kang, Dong-Min; Ko, Yoon-Joo; Ra, Moon-Jin; Jung, Sang-Mi; Yu, Jeong-Nam; Ahn, Mi-Jeong; Kim, Ki Hyun.* Chaenomelin, a New Phenolic Glycoside and anti-Helicobacter pylori Phenolic Compounds from the Leaves of Salix chaenomeloides. Plants 2024, 13, 701.
395. Lee, Seulah;a Jang, Mina;a Ryoo, Rhim; Roh, Jongtae; Ko, Sung-Kyun;* Kim, Ki Hyun.* New autophagy-modulating lanostane-type triterpenoids from a hallucinogenic poisonous mushroom Gymnopilus orientispectabilis. Arch. Pharm. Res. 2024, 47, 272–287.
394. Lee, Bum Soo;† Lee, Yun Young;† Lee, Seoung Rak;† Jang, Yoon Seo; Ryoo, Rhim; Park, Wooram; Kim, Se-Na; Lee, Soah;* Park, Chun Gwon;* Kim, Ki Hyun.* Isolation of Macrocyclic Trichothecene Mycotoxins from the Lethal Toxic Mushroom Podostroma cornu-damae and their Cytotoxic Activities. Separations 2024, 11, 65.
393. Kim, Tae-Young;† Lee, Bum Soo;† Jo, Beom-Geun;† Heo, Seong Pil; Jung, Young Suk; Kim, Su-Nam; Kim, Ki Hyun;* Yang, Min Hye.* Iridoid Glycosides and Coumarin Glycoside Derivatives from the Roots of Nymphoides peltata and Their In Vitro Wound Healing Properties. Int. J. Mol. Sci. 2024, 25, 1268.
392. Lee, Jihyun; Hwang, Gui Won; Lee, Bum Soo; Park, No-June; Kim, Su-Nam; Lim, Dohyun; Kim, Da Wan; Lee, Yeon Soo; Park, Hyoung-Ki; Kim, Seulgi; Kim, Jin Woong; Yi, Gi-Ra; Kim, Ki Hyun;† Pang, Changhyun.† Artificial octopus-limb-like adhesive patches for cupping-driven transdermal delivery with nanoscale control of stratum corneum. ACS Nano 2024, 18, 5311–5321.
391. Kim, Woo Hee;+ Song, Seon Bin;+ Lee, Da Eun; Goswami, Prithwish; Chung, You Kyoung; Choi, Sohyeong; Jung, Won Hee; Choi, Sang Un; Ham, Shinwon; Oh, Yujin; Kim, Ki Hyun;* Huh, Joonsuk;** Bae, Han Yong.*** Pinacolborane-Assisted Superacid Organocatalysis Enabled Direct Access to Cytotoxic Alkyl N-Cbz Amines. Cell Rep. Phys. Sci. 2024, 5, 101786.
390. Hwang, Su Jung;† Cho, Seung Hye;† Bang, Hye Jung; Hong, Joo-Hyun; Kim, Ki Hyun;* Lee, Hyo-Jong.* 1,8-Dihydroxy-3-methoxy-anthraquinone inhibits tumor angiogenesis through HIF-1α downregulation. Biochem. Pharmacol. 2024, 220, 115972.
389. Li, Yuankai;† Kim, Min-Cheol;† Xi, Chengkai; Hong, Won Tae; Kim, Jaekyum; Bae, Geunsu; Jang, Yoon Seo; Jeong, Se Yun; Sim, Eunji; Choi, Chang Hyuck; Kim, Tae-Hoon; Kim, Ki Hyun;* Kim, Jung Kyu.* A natural molecule-driven organometallic conformal overlayer for high efficiency photoelectrochemical water splitting. Appl. Catal. B: Environ. 2024, 343, 123516.
388. Cho, Yeo Rang;1 Lee, Sanghun;1 Kim, Hyoju;1 Park, Eon Chung; Jeong, Se Yun; Hamishehkar, Hamed; Jung, Su Myung;* Kim, Ki Hyun.* Pinuseldarone, a Clerodane-type Diterpene from Pinus eldarica Needles and Phytochemicals as Novel Agents for Regulating Brown Adipogenesis and Thermogenesis. J. Nat. Prod. 2024, 87, 58−67.
387. Jeong, Se Yun;† Lee, Kwang Ho;† Kim, Jae Kwan; Ahn, Dohee; Kim, Hyemin; Chung, Sang J.; Yoon, Sun-Young;* Kim, Ki Hyun.* Ginkgolic Acid Derivatives from Ginkgo biloba Show Inhibitory Activity against Protein Tyrosine Phosphatases Associated with Insulin Resistance. Appl. Sci. 2023, 13, 13220.
386. Kim, Tae-Young;† Lee, Bum Soo;† Jo, Beom-Geun;† Heo, Seong Pil; Keem, Min-Ji; Kwon, Taek-Hwan; Kim, Su-Nam;* Kim, Ki Hyun;* Yang, Min Hye.* 3′′′-O-Foliamenthoyl-Rutin, a New Flavonoid Glycoside from the Roots of Nymphoides peltate. Plants 2023, 12, 4083.
385. Huo, Chen;† Nguyena, Quynh Nhu;† Alishir, Akida; Ra, Moon-Jin; Jung, Sang-Mi; Yu, Jeong-Nam; Gwon, Hui-Jeong; Kang, Ki Sung;* Kim, Ki Hyun.* Global Natural Products Social (GNPS)-Molecular Networking Guided Isolation of Phenolic Compounds from Ginkgo biloba Fruits and Identification of Estrogenic Phenolic Glycosides. Plants 2023, 12, 3970.
384. Lim, Jae Sung;† Hong, Joo-Hyun;† Lee, Da Young; Li, Xiangying; Lee, Da Eun; Choi, Jeong Uk; Lee, Kwang Youl;* Kim, Ki Hyun;* Cho, Young-Chang.* 6-Pentyl-α-Pyrone from Trichoderma gamsii Inhibits Excessive Oxidative and Inflammatory Responses in Lipopolysaccharide-stimulated Mouse Macrophages. Antioxidants 2023, 12, 2028.
383. Jang, Yoon Seo;† Lee, Da Eun;† Ju, Dong U;† Jeong, Se Yun; Ko, Yoon-Joo;Pang, Changhyun; Kang, Ki Sung; Gwon, Hui-Jeong; Yoo, Hee Min;* Kim, Ki Hyun.* Antiviral Effects of Secondary Metabolites from Jatropha podagrica Leaves against the Pseudotyped Virus of SARS-CoV-2 Omicron. Plants 2023, 12, 3942.
382. Kim, Tae-Young; Park, No-June; Jo, Beom-Geun; Lee, Bum Soo; Keem, Min-Ji; Kwon, Taek-Hwan; Kim, Ki Hyun;* Kim, Su-Nam;* Yang, Min Hye.* Anti-Wrinkling Effect of 3,4,5-tri-O-Caffeoylquinic Acid from the Roots of Nymphoides peltata through MAPK/AP-1, NF-κB, and Nrf2 Signaling in UVB-Irradiated HaCaT Cells. Antioxidants 2023, 12, 1899.
381. Seibel, Elena; Um, Soohyun; Dayras, Marie; Bodawatta, Kasun H.; de Kruijff, Martinus; Jønsson, Knud A.; Poulsen, Michael; Kim, Ki Hyun;* Beemelmanns, Christine.* Genome mining for macrolactam-encoding gene clusters allowed for the network-guided isolation of β-amino acid-containing cyclic derivatives and heterologous production of ciromicin A. Commun. Chem. 2023, 6, 257.
380. Jeong, Se Yun;† Yu, Hyung-Seok;† Ra, Moon-Jin; Jung, Sang-Mi; Yu, Jeong-Nam; Kim, Jin-Chul;* Kim, Ki Hyun.* Phytochemical Investigation of Equisetum arvense and Evaluation of Their Anti-Inflammatory Potential in TNFα/INFγ-Stimulated Keratinocytes. Pharmaceuticals 2023, 16, 1478.
379. Timilsina, Arjun Prasad;† Raut, Bimal Kumar;† Huo, Chen;† Khadayat, Karan; Budhathoki, Prakriti; Ghimire, Mandira; Budhathoki, Rabin; Aryal, Niraj; Kim, Ki Hyun;* Parajuli, Niranjan.* Metabolomics and molecular networking approach for exploring the anti-diabetic activity of medicinal plants. RSC Adv. 2023, 13, 30665.
378. Lee, Bum Soo;† Jung, Su Myung;† Ryoo, Rhim; Choi, Sang Un; An, Seongpil;* Kim, Ki Hyun.* N-Hydroxy-Phe-Phe, a New Dipeptide and Cytotoxic Macrocyclic Trichothecenes from a Lethal Toxic Mushroom Podostroma cornu-damae. Org. Biomol. Chem. 2023, 21, 8521.
377. Lee, Da Eun;† Park, Kun Hee;† Hong, Joo-Hyun; Kim, Seon Hee; Park, Ki-Moon;* Kim, Ki Hyun.* Anti-osteoporosis effects of triterpenoids from the fruit of sea buckthorn (Hippophae rhamnoides) through the promotion of osteoblast differentiation in mesenchymal stem cells, C3H10T1/2. Arch. Pharm. Res. 2023, 46, 771–781.
376. Jo, Hongseok;1 Park, Dogun;1 Joo, Minkyeong;1 Choi, Daekyu; Kang, Jisong; Ha, Jeong-Myeong; Kim, Ki Hyun;* Kim, Kwang Ho;* An, Seongpil.* Performance-enhanced eco-friendly triboelectric nanogenerator via wettability manipulation of lignin. EcoMat 2023, 5, e12413.
375. You, Chang-Lim;# Lee, Sang-Jin;# Lee, Jinwoo; Vuong, Tuan Anh; Lee, Hye-Young; Jeong, Se Yun; Alishir, Akida; S. Walker, Allison; Bae, Gyu-Un;* Kim, Ki Hyun;* Kang, Jong-Sun.* Inonotus obliquus upregulates muscle regeneration and augments function through muscle oxidative metabolism. Int. J. Biol. Sci. 2023, 19, 4898-4914.
374. Koher, Grant; Khan, Ajmal; Suarez-vega, Gabriel, Meesakul, Pornphimon; Bacani, Ann-Janin; Kohno, Tomomi; Zhu, Xuewei; Kim, Ki Hyun; Cao, Shugeng;* Jia, Zhenquan.* A Comprehensive Insight into Māmaki (Pipturus albidus): Its Ethnomedicinal Heritage, Human Health Research, and Phytochemical Properties. Plants 2023, 12, 2924.
373. Lee, Seung-Eun;†,* Jeong, Se Yun;† Jang, Yoon Seo;† Cho, Kwang-Jin; Lee, Jeonghoon; Lee, Yunji; Kim, Ki Hyun.* Isolation and Structural Elucidation of Unreported Prenylhydroquinone Glycoside from Sedum kamtschaticumLeaves and Its Effect on Hyperphosphorylated Tau Production in Aβ1–42-treated SH-SY5Y Cells. Separations 2023, 10, 428.
372. Jeong, Se Yun;1 Alishir, Akida;1 Zhang, Shuxiang; Zhang, Yinglao; Choi, Sohyeong; Pang, Changhyun; Bae, Han Yong;* Jung, Won Hee;* Kim, Ki Hyun.* Identification of Obscurolide-type Metabolites and Antifungal Metabolites from the Termite-associated Streptomyces neopeptinius BYF101. J. Nat. Prod. 2023, 86, 1891-1900.
371. Fahmy, Nouran M.; Gamal El-Din, Mariam I.; Salem, Maha M.; Rashedy, Sarah H.; Lee, Gyu Sung; Jang, Yoon Seo; Kim, Ki Hyun; Kim, Chung Sub;* El-Shazly, Mohamed;* Fayez, Shaimaa. Enhanced Expression of p53 and Suppression of PI3K/Akt/mTOR by Three Red Sea Algal Extracts: Insights on Their Composition by LC-MS-Based Metabolic Profiling and Molecular Networking. Mar. Drugs 2023, 21, 404.
370. Lee, Sullim;† Choi, Yea Jung;† Huo, Chen;† Alishir, Akida; Kang, Ki Sung, Park, Il-Ho; Jang, Taesu;* Kim, Ki Hyun.* Laricitrin 3-Rutinoside from Ginkgo biloba Fruits Prevents Damage in TNF-α-Stimulated Normal Human Dermal Fibroblasts. Antioxidants 2023, 12, 1432.
369. Lee, Dahae;† Lee, Seulah;† Jang, Yoon Seo; Ryoo, Rhim; Kim, Jung Kyu; Kang, Ki Sung;* Kim, Ki Hyun.* N,N-Dimethyl-Anthranilic Acid from Calvatia nipponica Mushroom Fruiting Bodies Induces Apoptotic Effects on MDA-MB-231 Human Breast Cancer Cells. Nutrients 2023, 15, 3091.
368. Ham, Song Lim; Lee, Tae Hyun; Kim, Kyung Jun; Kim, Jung Ha; Hwang, Su Jung; Lee, Sun Ho; Yu, Jae Sik; Kim, Ki Hyun; Lee, Hyo-Jong; Lee, Wonsik; Kim, Chung Sub.* Discovery and Biosynthesis of Imidazolium Antibiotics from a Probiotic Bacillus licheniformis. J. Nat. Prod. 2023, 86, 850–859.
367. Huo, Chen;† Lee, Sullim;† Yoo, Min Jeong; Lee, Bum Soo; Jang, Yoon Seo; Kim, Ho Kyong; Lee, Seulah; Bae, Han Yong;* Kim, Ki Hyun.* Methoxyflavones from Black Ginger (Kaempferia parviflora Wall. ex Baker) and their Inhibitory Effect on Melanogenesis in B16F10 Mouse Melanoma Cells. Plants 2023, 12, 1183.
366. Lee, Joo-Eun;1 Jeong, Se Yun;1 Li, Zijun; Kim, Hyun-Yi; Kim, Hyun-Woo; Yoo, Min Jeong; Jang, Hee Joo; Kim, Do-Kyun; Cho, Namki; Yoo, Hee Min;* Kim, Ki Hyun.* Development of a screening platform to discover natural products active against SARS-CoV-2 infection using lung organoid models. Biomater. Res. 2023, 27, 18.
365. Kim, Hye Ryeong; Kim, Jonghwan; Yu, Jae Sik; Lee, Bum Soo; Kim, Ki Hyun; Kim, Chung Sub.* Isolation, structure elucidation, total synthesis, and biosynthesis of dermazolium A, an antibacterial imidazolium metabolite of a vaginal bacterium Dermabacter vaginalis. Arch. Pharm. Res. 2023, 46, 35-43.
364. Jang, Yoon Seo;† Lee, Da Eun;† Hong, Joo-Hyun; Kim, Kyung Ah; Kim, Bora; Cho, Yeo Rang; Ra, Moon-Jin; Jung, Sang-Mi; Yu, Jeong-Nam; An, Seongpil;* Kim, Ki Hyun.* Phytochemical Investigation of Marker Compounds from Korean Indigenous Salix Species and Their Antimicrobial Effects. Plants 2023, 12, 104.
363. Cho, Hyejin; Kim, Ki Hyun; Han, Sin Hee; Kim, Hak-Jae; Cho, Ik-Hyun; Lee, Sanghyun.* Structure Determination of Heishuixiecaoline A from Valeriana fauriei and Its Content from Different Cultivated Regions by HPLC/PDA Analysis. Nat. Prod. Sci. 2022, 28, 181-186.
362. Nguyen, Quynh Nhu;† Lee, Seoung Rak;† Kim, Baolo;† Hong, Joo-Hyun; Jang, Yoon Seo; Lee, Da Eun; Pang, Changhyun; Kang, Ki Sung;* Kim, Ki Hyun.* Estrogenic Activity of 4-Hydroxy-Benzoic Acid from Acer tegmentosum via Estrogen Receptor α-Dependent Signaling Pathways. Plants 2022, 11, 3387.
361. Kim, Eun-nam; Trang, Nguyen Minh; Kang, Heesun; Kim, Ki Hyun;* Jeong, Gil-Saeng.* Phytol Suppresses Osteoclast Differentiation and Oxidative Stress through Nrf2/HO-1 Regulation in RANKL-induced RAW264.7 Cells. Cells 2022,11, 3596.
360. Lee, Bum Soo; So, Hae Min; Kim, Sil; Kim, Jung Kyu; Kim, Jin-Chul; Kang, Dong-Min; Ahn, Mi-Jeong; Ko, Yoon-Joo; Kim, Ki Hyun.* Comparative evaluation of bioactive phytochemicals in Spinacia oleracea cultivated under greenhouse and open field conditions. Arch. Pharm. Res. 2022, 45, 795–805.
359. Lee, Sullim;† Choi, Yea Jung;† Lee, Seulah;† Kang, Ki Sung; Jang, Taesu;* Kim, Ki Hyun.* Protective Effects of Withagenin A Diglucoside from Indian Ginseng (Withania somnifera)against Human Dermal Fibroblasts Damages by TNF-α stimulation. Antioxidants 2022, 11, 2248.
358. Lee, Bum Soo; Kang, Heesun; Yoo, Min Jeong; Jeong, Se Yun; Ko, Yoon-Joo; Kim, Ki Hyun.* Anti-Adipogenic Effect of Terminalin Isolated from the Seeds of Wild Mango (Irvingia gabonensis) on 3T3-L1 Preadipocytes. Drug Targets and Therapeutics 2022, 1, 12-18.
357. Lee, Bum Soo; Ryoo, Rhim; Park, Jin Song; Choi, Sang Un; Jeong, Se Yun; Ko, Yoon-Joo; Kim, Jung Kyu; Kim, Jin-Chul;* Kim, Ki Hyun.* Meyeroguilline E, a new isoindolinone alkaloid from the poisonous mushroom Chlorophyllum molybdites, and identification of compounds with multidrug resistance (MDR) reversal activities. ACS Omega 2022, 7, 39456–39462.
356. Kim, Hee Jung;† Lee, Da Eun;† Park, Eon Chung; Ra, Moon-Jin; Jung, Sang-Mi; Yu, Jeong-Nam; Um, Sung Hee;* Kim, Ki Hyun.* Anti-adipogenic Effects of Salicortin from the Twigs of Weeping Willow (Salix pseudolasiogyne) in 3T3-L1 Cells. Molecules 2022, 27, 6954.
355. Kim, Hee Jung;† Jang, Yoon Seo;† Ha, Ji Won; Ra, Moon-Jin; Jung, Sang-Mi; Yu, Jeong-Nam; Kim, Kyunga; Kim, Ki Hyun;* Um, Sung Hee.* Bioactive Phytochemicals from Salix pseudolasiogyne Twigs: Anti-adipogenic effect of 2′-O-Acetylsalicortin in 3T3-L1 Cells. Int. J. Mol. Sci. 2022, 23, 12006.
354. Choi, Yea Jung;1 Alishir, Akida;1 Jang, Taesu; Kang, Ki Sung; Lee, Sullim;* Kim, Ki Hyun.* Anti-skin aging effects of indole alkaloid N-glycoside from ginkgo fruit (Ginkgo biloba fruit) on TNF-α-exposed human dermal fibroblasts. J. Agric. Food Chem. 2022, 70, 13651−13660.
Lee, Dahae;†, Yu, Jae Sik;† Ha, Ji Won; Lee, Seoung Rak; Lee, Bum Soo; Kim, Jin-Chul; Kim, Jung Kyu; Kang, Ki Sung;* Kim, Ki Hyun.* Antitumor Potential of Withanolide Glycosides from Ashwagandha (Withania somnifera) on Apoptosis of Human Hepatocellular Carcinoma Cells and Tube Formation in Human Umbilical Vein Endothelial Cells. Antioxidants 2022, 11, 1761.
Lee, Bum Soo;† Cho, Ye-Ryeong;† Jeong, Minju; Jang, Yoon Seo; Kim, Jin-Chul; Byun, Sanguine;* Kim, Ki Hyun.* Anti-atopic Dermatitis Activity of Cornus walteri and Identification of the Bioactive Compounds. Appl. Sci. 2022, 12, 8857.
Park, Kun Hee;† Hong, Joo-Hyun;† Kim, Seon Hee; Kim, Jin-Chul; Kim, Ki Hyun;* Park, Ki-Moon.* Anti-osteoporosis Effects of the Fruit of Sea Buckthorn (Hippophae rhamnoides) through Promotion of Osteogenic Differentiation in Ovariectomized Mice. Nutrients 2022, 14, 3604.
Jeong, Se Yun;1 Na, Myung Woo;1 Park, Eon Chung;1 Kim, Jin-Chul; Kang, Dong-Min; Hamishehkar, Hamed; Ahn, Mi-Jeong; Kim, Jung Kyu;* Kim, Ki Hyun.* Labdane-type Diterpenes from Pinus eldarica Needles and Their Anti-Helicobacter pylori Activity. ACS Omega 2022, 7, 29502–29507.
Na, Myung Woo;1 Jeong, Se Yun;1 Ko, Yoon-Joo; Kang, Dong-Min; Pang, Changhyun; Ahn, Mi-Jeong; Kim, Ki Hyun.* Chemical Investigation of Tetradium ruticarpum Fruits and their Antibacterial Activity against Helicobacter pylori. ACS Omega 2022, 7, 23736–23743.
Babaie, Soraya; Taghvimi, Arezou; Hong, Joo-Hyun; An, Seongpil;* Hamishehkar, Hamed;* Kim, Ki Hyun.* Recent advances in pain management based on nanoparticle technologies. J. Nanobiotechnology 2022, 20, 290.
Zhou, Lingfeng;† Wang, Junyong;† Wu, Fei; Yin, Caiping; Kim, Ki Hyun; Zhang, Yinglao.* Termite nest associated Bacillus siamensis YC-9 mediated biocontrol of Fusarium oxysporum f. sp. cucumerinum. Front. Microbiol. 2022, 13, 893393.
Lee, Jihyun;1 Lee, Bum So;1 Baik, Sangyul; Kim, Da Wan; Park, No-June; Lee, Jin Woo; Bong, Sim-Kyu; Lee, Sang Heon; Kim, Su-Nam; Song, Jin Ho; Kim, Jung Kyu; Yi, Gi-Ra; Kim, Ki Hyun;⁎ Pang, Changhyun.⁎ Ultra-intimate hydrogel hybrid skin patch with asymmetric elastomeric spatula-like cylinders. Chem. Eng. J. 2022, 444, 136581.
Lee, Seoung Rak; Schalk, Felix; Schwitalla, Jan W.; Guo, Huijuan; Yu, Jae Sik; Song, Moonyong; Jung, Won Hee; de Beer, Z. Wilhelm; Beemelmanns, Christine;* Kim, Ki Hyun.* GNPS-Guided Discovery of Madurastatin Siderophores from the Termite-Associated Actinomadura sp. RB99. Chem. Eur. J. 2022, 28, e202200612.
Kang, Heesun;† Lee, Dahae;† Kang, Ki Sung;* Kim, Ki Hyun.* A New Labdane-type Diterpene, 6-O-Acetyl-(12R)-epiblumdane, from Stevia rebaudiana Leaves with Insulin Secretion Effect. Biomedicines 2022, 10, 839.
Mazloum-Ravasan, Sahand; Mohammadi, Maryam; Hiagh, Elaheh Madadi; Ebrahimi, Alireza; Hong, Joo-Hyun; Hamishehkar, Hamed;* Kim, Ki Hyun.* Nano-liposomal zein hydrolysate for improved apoptotic activity and therapeutic index in lung cancer treatment. Drug Deliv. 2022, 29, 1049–1059.
Na, Myung Woo; Lee, Eunjin; Kang, Dong-Min; Jeong, Se Yun; Ryoo, Rhim; Kim, Chul-Young; Ahn, Mi-Jeong; Kang, Kyo Bin;* Kim, Ki Hyun.* Identification of Antibacterial Sterols from Korean Wild Mushroom Daedaleopsis confragosa via Bioactivity- and LC-MS/MS profile-guided Fractionation. Molecules 2022, 27, 1865.
Ha, Ji Won; Yu, Jae Sik; Lee, Bum Soo; Kang, Dong-Min; Ahn, Mi-Jeong;* Kim, Jung Kyu;* Kim, Ki Hyun.* Structural Characterization of Withanolide Glycosides from the Roots of Withania somnifera and their Potential Biological Activities. Plants 2022, 11, 767.
Aboushanab, Saied A.;* Shevyrin, Vadim A.; Slesarev, Grigory P.; Melekhin, Vsevolod V.; Shcheg-lova, Anna V.; Makeev, Oleg G.; Kovaleva, Elena G.; Kim, Ki Hyun.* Antioxidant and Cytotoxic Activities of Kudzu Roots and Soy Molasses against Pediatric Tumors and Phytochemical Analysis of Isoflavones using HPLC-DAD-ESI-HRMS. Plants 2022, 11, 741.
Park, Dogun;† Hong, Joo-Hyun;† Choi, Daekyu; Kim, Donghyeun; Jung, Won Hee; Yoon, Sam S.;* Kim, Ki Hyun;* An, Seongpil.* Biocompatible and Mechanically-reinforced Tribopositive Nanofiber Mat for Wearable and Antifungal Human Kinetic Energy Harvester based on Wood-derived Natural Product. Nano Energy 2022, 96, 107091.
Lee, Sullim; Jang, Taesu; Kim, Ki Hyun;* Kang, Ki Sung.* Improvement of Damage in Human Dermal Fibroblasts by 3,5,7-Trimethoxyflavone from Black Ginger (Kaempferia parviflora). Antioxidants 2022, 11, 425.
Yoon, Sun-Young;† Kim, Jinsoo;† Lee, Bum Soo;† Baek, Su Cheol; Chung, Sang J.;* Kim, Ki Hyun.* Terminalin from African Mango (Irvingia gabonensis) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases. Biomolecules 2022, 12, 321.
Yu, Jae Sik; Jeong, Se Yun; Li, Chunshun; Oh, Taehoon; Kwon, Mincheol; Ahn, Jong Seog; Ko, Sung-Kyun; Ko, Yoon-Joo; Cao, Shugeng; Kim, Ki Hyun.* New phenalenone derivatives from the Hawaiian volcanic soil-associated fungus Penicillium herquei FT729 and their inhibitory effects on indoleamine 2,3-dioxygenase 1 (IDO1). Arch. Pharm. Res. 2022, 45, 105-113.
Park, Moon Nyeo;‡ Jeon, Hee Won;‡ Rahman, Md. Ataur; Park, Se Sun; Jeong, Se Yun; Kim, Ki Hyun; Kim, Sung-Hoon; Kim, Woojin; Kim, Bonglee.* Daemonorops dracoBlume induces apoptosis against acute myeloid leukemia cells via regulation of miR-216b/c-Jun signal pathway. Front. Oncol. 2022, 21, 808174.
Lee, Seulah; Jeong, Se Yun; Nguyen, Dieu Linh; So, Jae Eun; Kim, Ki Hyun; Kim, Ji Hee; Han, Se Jong; Suh, Sung-Suk; Lee, Jun Hyuck; Youn, Ui Joung.* Stereocalpin B, a New Cyclic Depsipeptide from the Antarctic Lichen Ramalina terebrata. Metabolites 2022, 12, 141.
Lee, Seoung Rak; Lee, Bum Soo; Yu, Jae Sik; Kang, Heesun; Yoo, Min Jeong; Yi, Sang Ah; Han, Jeung-Whan; Kim, Sil; Kim, Jung Kyu; Kim, Jin-Chul; Kim, Ki Hyun.* Identification of anti-adipogenic withanolides from the roots of Indian ginseng (Withania somnifera). J. Ginseng Res. 2022, 46, 357-366.
Lee, Seulah;† Yu, Jae Sik;† Lee, Seoung Rak;† Kim, Ki Hyun.* Non-peptide secondary metabolites from poisonous mushrooms: overview of chemistry, bioactivity, and biosynthesis. Nat. Prod. Rep. 2022, 39, 512–559.
Min, Hyeongho;1 Baik, Sangyul;1 Lee, Jihyun; Kim, Da Wan; Song, Jin Ho; Kim, Ki Hyun; Kim, Min-Seok;* Pang, Changhyun.* Enhanced biocompatibility and multidirectional wet adhesion of insect-like synergistic wrinkled pillars with microcavities. Chem. Eng. J. 2022, 429, 132467.
Lee, Seulah; Alishir, Akida; Kim, Tae Wan; Kang, Dong-Min; Ryoo, Rhim; Pang, Changhyun; Ahn, Mi-Jeong; Kim, Ki Hyun.* First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pyloriCompounds. Pharmaceuticals 2022, 15, 152.
Lee, Seulah;† Kim, Tae Wan;† Lee, Yong Hoon; Kang, Dong-Min; Ryoo, Rhim; Ko, Yoon-Joo; Ahn, Mi-Jeong; Kim, Ki Hyun.* Two New Fatty Acid Derivatives, Omphalotols A and B and Anti-Helicobacter pylori Fatty Acid Derivatives from Poisonous Mushroom Omphalotus japonicus. Pharmaceuticals 2022, 15, 139.
Huong, Pham; Doan, Thi Phuong; Kim, Hyun Woo; Kim, Tae Wan; Park, So-Yeon; Kim, Hangun; Lee, Mina; Kim, Ki Hyun; Oh, Won Keun; Lim, Young Woon; Kang, Kyo Bin.* Cyclohumulanoid Sesquiterpenes Induced by the Non-competitive Co-culture of Two Basidiomycetous Fungi Phellinus orientoasiaticus and Schizopora flavipora. J. Nat. Prod. 2022, 85, 511−518.
Lee, Dahae;† Ko, Yuri;† Pang, Changhyun; Ko, Yoon-Joo; Choi, You-Kyoung; Kim, Ki Hyun;* Kang, Ki Sung.* Estrogenic Activity of Mycoestrogen (3β,5α,22E)-Ergost-22-en-3-ol via Estrogen Receptor α-Dependent Signaling Pathways in MCF-7 Cells. Molecules 2022, 27, 36.
Jo, Beom-Geun; Park, Young-Hun; Kim, Ki Hyun; Kim, Su-Nam;* Yang, Min Hye.* Simultaneous Determination of Four Marker Compounds in Lobelia chinensis Lour. Extract by HPLC-PDA. Appl. Sci. 2021, 11, 12080.
Alishir, Akida; Kim, Ki Hyun.* Antioxidant Phenylpropanoid Glycosides from Ginkgo biloba Fruit and Identification of a New Phenylpropanoid Glycoside, Ginkgopanoside. Plants 2021, 10, 2702.
Paje, Leo Adrianne; Lee, Hak-Dong; Choi, Jungwon; Kim, Juree; Kim, Ki Hyun; Yu, A Ram; Bae, Min-Jung; Lee, Sanghyun.* Phytochemical constituents from the aerial parts of Salvia plebeian. J. Appl. Biol. Chem. 2021, 64, 391−397.
Lee, Dahae;† Lee, Seoung Rak;† Park, Bang Ju; Song, Ji Hoon; Kim, Jung Kyu; Ko, Yuri; Kang, Ki Sung;* Kim, Ki Hyun.* Identification of Renoprotective Phytosterols from Fruits of Mulberry (Morus alba) Against Cisplatin-Induced Cytotoxicity in LLC-PK1 Kidney Cells. Plants 2021, 10, 2481.
Yu, Jae Sik;a Kim, Ji-Hoon;a Rashan, Luay; Kim, Inseo; Lee, Wonsik;* Kim, Ki Hyun.* Potential Antimicrobial Activity of Galloyl-flavonoid Glycosides from Woodfordia uniflora against Methicillin-resistant Staphylococcus aureus. Front. Microbiol. 2021, 12, 784504.
Kang, Heesun;† Yoo, Min Jeong;† Yi, Sang Ah; Kim, Tae Wan; Ha, Ji Won; Na, Myung Woo; Park, Kun Hee; Kim, Seon‑Hee; Han, Jeung-Whan; Jang, Tae Su; Kim, Ki Hyun.* Phytochemical Constituents Identified from the Aerial Parts of Lespedeza cuneata and their Effects on Lipid Metabolism during Adipocyte Maturation. Separations 2021, 8, 203.
Lee, Yong Hoon;† Hong, Joo-Hyun;† Park, Kun Hee; Kim, Seon‑Hee; Kim, Jin-Chul; Kim, Do Hoon; Park, Yu Hwa; Lee, Kye Wan; Kim, Jung Kyu;* Kim, Ki Hyun.* Phytochemical Investigation of Bioactive Compounds from White Kidney Beans (Fruits of Phaseolus multiflorus var. albus): Identification of Denatonium with Osteogenesis-Inducing Effect. Plants 2021, 10, 2205.
Yun, Chae-Eun;† So, Hyun-Kyung;† Vuong, Tuan Anh ; Na, Myung Woo; Anh, Subin; Lee, Hyo-Gun; Kim, Ki Hyun; Kang, Jong-Sun; Bae, Gyu-Un;* Lee, Sang-Jin.* Aronia upregulates myogenic differentiation and augments muscle mass and function through muscle metabolism. Front. Nutr. 2021, 8, 753643.
Lee, Bum Soo;† Yoo, Min Jeong;† Kang, Heesun;† Lee, Seoung Rak; Kim, Sil; Yu, Jae Sik; Kim, Jin-Chul; Jang, Tae Su; Pang, Changhyun;* Kim, Ki Hyun.* Withasomniferol D, a New Anti-adipogenic Withanolide from the Roots of Ashwagandha (Withania somnifera). Pharmaceuticals 2021, 14, 1017.
Lee, Kwang Ho;1 Jeong, Se Yun;1 Park, Kun Hee; Kim, Seon-Hee; Ko, Yoon-Joo; Kim, Jin-Chul; Kim, Jung Kyu;* Kim, Ki Hyun.* Ginkgonitroside, a new nitrophenyl glycoside and bioactive compounds from Ginkgo biloba leaves controlling adipocyte and osteoblast differentiation. Bioorg. Med. Chem. Lett. 2021, 50, 128322.
Kwon, Haeun;# Nguyen, Quynh Nhu;# Na, Myung Woo; Kim, Ki Hyun; Guo, Yuanqiang; Yim, Joung Han; Shim, Sang Hee; Kim, Jae-Jin; Kang, Ki Sung;* Lee, Dongho.* A new α-pyrone from Arthrinium pseudosinenseculture medium and its estrogenic activity in MCF-7 cells. J. Antibiot. 2021, 74, 893–897.
Lee, Dahae; Lee, Seoung Rak; Kang, Ki Sung;* Kim, Ki Hyun.* Bioactive Phytochemicals from Mulberry: Potential Anti-Inflammatory Effects in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. Int. J. Mol. Sci. 2021, 22, 8120.
Ghaffari, Tayyebeh; Hong, Joo-Hyun; Asnaashari, Solmaz; Farajnia, Safar; Delazar, Abbas; Hamishehkar, Hamed;* Kim, Ki Hyun.* Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers. Int. J. Mol. Sci. 2021, 22, 6636.
Lee, Seoung Rak; Guo, Huijuan; Yu, Jae Sik; Park, Minji; Dahse, Hans-Martin; Jung, Won Hee; Beemelmanns, Christine;* Kim, Ki Hyun.* Revised structural assignment of azalomycins based on genomic and chemical analysis. Org. Chem. Front. 2021, 8, 4791–4798.
Lee, Dahae;# Yu, Jae Sik;# Ryoo, Rhim; Kim, Jin-Chul; Jang, Tae Su; Kang, Ki Sung;* Kim, Ki Hyun.* Pulveraven A from the fruiting bodies of Pulveroboletus ravenelii induces apoptosis in breast cancer cell via extrinsic apoptotic signaling pathway. J. Antibiot. 2021, 74, 752–757.
Ghaffari, Tayyebeh; Asnaashari, Solmaz; Irannejad, Ebrahim; Delazar, Abbas; Farajnia, Safar; Hong, Joo-Hyun; Pang, Changhyun; Hamishehkar, Hamed;* Kim, Ki Hyun.* Comparative Evaluation of Apoptosis Induction Using Needles, Bark, and Pollen Extracts and Essential Oils of Pinus eldarica in Lung Cancer Cells. Appl. Sci. 2021, 11, 5763.
Ha, Sang Keun;† Kang, Min Cheol;† Lee, Seulah;† Darlami, Om; Shin, Dongyun; Choi, Inwook;* Kim, Ki Hyun;* Kim, Sun Yeou.* Generation of Stilbene Glycoside with Promising Cell Rejuvenation Activity through Biotransformation by the Entomopathogenic Fungus Beauveria bassiana. Biomedicines 2021, 9, 555.
Lee, Dahae;1 Kim, Ki Hyun;1 Jang, Tae Su;* Kang, Ki Sung.* Identification of bioactive compounds from mulberry enhancing glucose-stimulated insulin secretion. Bioorg. Med. Chem. Lett. 2021, 43, 128096.
Lee, Kwang Ho;a Kim, Jung Kyu;a Yu, Jae Sik; Jeong, Se Yun; Choi, Jin Hee; Kim, Jin-Chul; Ko, Yoon-Joo; Kim, Seon-Hee; Kim, Ki Hyun.* Ginkwanghols A and B, osteogenic coumaric acid-aliphatic alcohol hybrids from the leaves of Ginkgo biloba. Arch. Pharm. Res. 2021, 44, 514–524.
Lee, Yong Hoon;† Jang, Hee Joo;† Park, Kun Hee; Kim, Seon‑Hee; Kim, Jung Kyu; Kim, Jin-Chul; Jang, Tae Su;* Kim, Ki Hyun.* Phytochemical Analysis of the Fruits of Sea Buckthorn (Hippophae rhamnoides): Identification of Organic Acid Derivatives. Plants 2021, 10, 860.
Lee, Seulah;# Kim, Chung Sub;# Yu, Jae Sik; Kang, Heesun; Yoo, Min Jeong; Youn, Ui Joung; Ryoo, Rhim; Bae, Han Yong; Kim, Ki Hyun.* Ergopyrone, a Styrylpyrone-Fused Steroid with a Hexacyclic 6/5/6/6/6/5 Skeleton from a Mushroom Gymnopilus orientispectabilis. Org. Lett. 2021, 23, 3315−3319.
Lim, Sung Ho;† Yu, Jae Sik;† Lee, Ho Seon; Choi, Chang-Ik;* Kim, Ki Hyun.* Antidiabetic Flavonoids from Fruits of Morus alba Promoting Insulin-stimulated Glucose Uptake via Akt and AMP-activated Protein Kinase Activation in 3T3-L1 Adipocytes. Pharmaceutics 2021, 13, 526.
Lee, Dahae; Alishir, Akida; Jang, Tae Su;* Kim, Ki Hyun.* Identification of Bioactive Natural Product from the Stems and Stem Barks of Cornus walteri: Benzyl Salicylate Shows Potential Anti-inflammatory Activity in Lipopolysaccharide-stimulated RAW 264.7 Macrophages. Pharmaceutics 2021, 13, 443.
Park, Yong Joo;1 Jeon, Mi Seon;1 Lee, Seulah;1 Kim, Jung Kyu; Jang, Tae Su; Chung, Kyu Hyuck; Kim, Ki Hyun.* Anti-fibrotic effects of brevilin A in hepatic fibrosis via inhibiting the STAT3 signaling pathway. Bioorg. Med. Chem. Lett. 2021, 41, 127989.
Kim, Ga-Ram; Kim, Eun-Nam; Park, Kyoung Jin; Kim, Ki Hyun;* Jeong, Gil-Saeng.* Inhibitory Effect of LGS and ODE Isolated from the twigs of Syringa oblata var. dilatata on RANKL Induced Osteoclastogenesis in Macrophages Cells. Molecules 2021, 26, 1779.
Kim, Eui Jin;† Seo, Ji Bin;† Yu, Jae Sik;† Lee, Seoyoung; Lim, Jae Sung; Choi, Jeong Uk; Lee, Chang-Min; Rashan, Luay; Kim, Ki Hyun;* Cho, Young-Chang.* Anti-inflammatory Effects of a Polyphenol, Catechin-7,4′-O-digallate, from Woodfordia uniflora by Regulating NF-κB Signaling Pathway in Mouse Macrophages. Pharmaceutics 2021, 13, 408.
Yoon, Sun-Young; Yu, Jae Sik; Hwang, Ji Young; So, Hae Min; Seo, Seung Oh; Kim, Jung Kyu; Jang, Tae Su; Chung, Sang J.;* Kim, Ki Hyun.* Phloridzin Acts as an Inhibitor of Protein-tyrosine Phosphatase MEG2 Relevant to Insulin Resistance. Molecules 2021, 26, 1612.
Lee, Dahae; Kim, Ki Hyun; Jang, Taesu;* Kang, Ki Sung.* (-)-Leucophyllone, a Tirucallane Triterpenoid from Cornus walteri Enhances Insulin Secretion in INS-1 Cells. Plants 2021, 10, 431.
Schorn, Michelle A.; Verhoeven, Stefan; Ridder, Lars; […]; Kim, Ki Hyun; […]; van der Hooft, Justin J. J. A community resource for paired genomic and metabolomic data mining. Nat. Chem. Biol. 2021, 17, 363–368.
Yu, Jae Sik;† Lim, Sung Ho;† Lee, Seoung Rak; Choi, Chang-Ik;* Kim, Ki Hyun.* Antioxidant and anti-inflammatory effects of white mulberry (Morus alba L.) fruits on lipopolysaccharide-stimulated RAW 264.7 macrophages. Molecules 2021, 26, 920.
So, Hae Min;1 Lee, Seul;1 Baek, Kwan-Hyuck; Roh, Hyun-Soo; Kim, Sil; Jo, Mun Seok; Baek, Su Cheol; Seok, Soonja; Ryoo, Rhim; Kim, Ki Hyun.* Bioactivity-based analysis and chemical characterization of cytotoxic compounds from a poisonous mushroom, Amanita spissacea, in human lung cancer cells in vitro. Nat. Prod. Res. 2021, 35, 649–654.
Pham, Huong; Lee, Kwang Ho; Jeong, Eunah; Woo, Sunmin; Yu, Jinsuh; Kim, Woo-Young; Lim, Young Woon; Kim, Ki Hyun;* Kang, Kyo Bin.* Species Prioritization Based on Spectral Dissimilarity: A Case Study of Polyporoid Fungal Species. J. Nat. Prod. 2021, 84, 298–309.
Baik, Sangyul;* Hwang, Gui Won; Jang, Siyeon; Jeong, Suyeon; Kim, Ki Hyun; Yang, Tae-Heon; Pang, Changhyun.* Bioinspired Microsphere-Embedded Adhesive Architectures for Electrothermally Actuating Transport Device of Dry/Wet Pliable Surfaces. ACS Appl. Mater. Interfaces 2021, 13, 6930–6940.
Alishir, Akida; Yu, Jae Sik; Park, Minji; Kim, Jin-Chul; Pang, Changhyun; Kim, Jung Kyu; Jang, Tae Su; Jung, Won Hee; Kim, Ki Hyun.* Ulmusakidian, a new coumarin glycoside and antifungal phenolic compounds from the root bark of Ulmus davidiana var. japonica. Bioorg. Med. Chem. Lett. 2021, 36, 127828.
Baek, Su Cheol; Yi, Sang Ah; Lee, Bum Soo; Yu, Jae Sik; Kim, Jin-Chul; Pang, Changhyun; Jang, Tae Su; Lee, Jaecheol;* Kim, Ki Hyun.* Anti-adipogenic Polyacetylene Glycosides from the Florets of Safflower (Carthamus tinctorius). Biomedicines 2021, 9, 91.
Lee, Yong Hoon; Yoon, Sun-Young; Baek, Jiyun; Kim, Sung Jin; Yu, Jae Sik; Kang, Heesun; Kang, Ki Sung; Chung, Sang J.; Kim, Ki Hyun.* Metabolite profile of cucurbitane-type triterpenoids of bitter melon (fruit of Momordica charantia) and their inhibitory activity against protein tyrosine phosphatases relevant to insulin resistance. J. Agric. Food Chem. 2021, 69, 1816−1830.
Kim, Eun-Nam; Kim, Ga-Ram; Yu, Jae Sik; Kim, Ki Hyun;* Jeong, Gil-Saeng.* Inhibitory Effect of (2R)-4-(4-hydroxyphenyl)-2-butanol 2-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside on RANKL-induced Osteoclast Differentiation and ROS generation in Macrophages. Int. J. Mol. Sci. 2021, 22, 222.
Oh, Taehoon; Kwon, Mincheol; Yu, Jae Sik; Jang, Mina; Kim, Gun-Hee; Kim, Ki Hyun;* Ko, Sung-Kyun;* Ahn, Jong Seog.* Ent-Peniciherqueinone Suppresses Acetaldehyde-Induced Cytotoxicity and Oxidative Stress by Inducing ALDH and Suppressing MAPK Signaling. Pharmaceutics 2020, 12, 1229.
Chae, Sook In;† Yi, Sang Ah;† Nam, Ki Hong; Park, Kyoung Jin; Yun, Jihye; Kim, Ki Hyun; Lee, Jaecheol; Han, Jeung-Whan.* Morolic Acid 3-O-Caffeate Inhibits Adipogenesis by Regulating Epigenetic Gene Expression. Molecules 2020, 25, 5910.
Park, Yong Joo;a Lee, Kwang Ho;a Jeon, Mi Seon; Lee, Yong Hoon; Ko, Yoon-Joo; Pang, Changhyun; Kim, Bonglee; Chung, Kyu Hyuck;* Kim, Ki Hyun.* Hepatoprotective Potency of Chrysophanol 8-O-Glucoside from Rheum palmatum L. against Hepatic Fibrosis via Regulation of the STAT3 Signaling Pathway. Int. J. Mol. Sci. 2020, 21, 9044.
Lee, Hyun-Su; Yu, Jae Sik; Kim, Ki Hyun;* Jeong, Gil-Saeng.* Diketoacetonylphenalenone, Derived from Hawaiian Volcanic Soil-Associated Fungus Penicillium Herquei FT729, Regulates T Cell Activation via Nuclear Factor-κB and Mitogen-Activated Protein Kinase Pathway. Molecules 2020, 25, 5374.
Lee, Dahae;† Yu, Jae Sik;† Huang, Peng; Qader, Mallique; Manavalan, Arulmani; Wu, Xiaohua; Kim, Jin-Chul; Pang, Changhyun; Cao, Shugeng;* Kang, Ki Sung;* Kim, Ki Hyun.* Identification of Anti-inflammatory Compounds from Hawaiian Noni (Morinda citrifolia L.) Fruit Juice. Molecules 2020, 25, 4968.
Lee, Kwang Ho; Yu, Jae Sik; Choi, Jin Hee; Kim, Seon‑Hee; Ko, Yoon-Joo; Pang, Changhyun; Kim, Ki Hyun.* Ginkgobilol, a new diarylpentanoid and an osteogenic diarylpentanoid analog from Ginkgo biloba leaves. Bioorg. Med. Chem. Lett. 2020, 30, 127641.
Yu, Jae Sik; Li, Chunshun, Kwon, Mincheol; Oh, Taehoon; Lee, Tae Hyun; Kim, Dong Hyun; Ahn, Jong Seog; Ko, Sung-Kyun; Kim, Chung Sub; Cao, Shugeng;* and Kim, Ki Hyun.* Herqueilenone A, a unique rearranged benzoquinone-chromanone from the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729. Bioorg. Chem. 2020, 105, 104397.
Lee, Sullim; Yu, Jae Sik; Phung, Hung Manh; Lee, Jeong Gun; Kim, Ki Hyun;* Kang, Ki Sung.* Potential Anti-Skin Aging Effect of (-)-Catechin Isolated from the Root Bark of Ulmus davidiana var. japonica in Tumor Necrosis Factor-α-Stimulated Normal Human Dermal Fibroblasts. Antioxidants 2020, 9, 981.
Kim, Yong-Goo; Komakech, Richard; Jeong, Dae Hui; Jeon, Kwonseok; Park, Yunmi; Lee, Tae Kyoung; Kim, Ki Hyun; Moon, Byeong Cheol; Kang, Youngmin. Verification of the Field Productivity and Bioequivalence of a Medicinal Plant (Polygonum multiflorum) Developed Using an In Vitro Culture Method. Plants 2020, 9, 1280.
Madadi, Elaheh; Mazloum-Ravasan, Sahand; Yu, Jae Sik; Ha, Ji Won; Hamishehka, Hamed;* Kim, Ki Hyun.* Therapeutic Application of Betalains: A Review. Plants 2020, 9, 1219.
Lee, Seulah; Lee, Dahae; Ryoo, Rhim; Kim, Jin-Chul; Park, Hyun Bong; Kang, Ki Sung; Kim, Ki Hyun.* Calvatianone, a Sterol Possessing a 6/5/6/5-Fused Ring System with a Contracted Tetrahydrofuran B-ring, from the fruiting bodies of Calvatia nipponica. J. Nat. Prod. 2020, 83, 2737–2742.
Lee, Seoung Rak; Schalk, Felix; Schwitalla, Jan W.; Benndorf, René; Vollmers, John; Kastner, Anne-Kristin; de Beer, Z. Wilhelm; Park, Minji; Ahn, Mi-Jeong; Jung, Won Hee; Beemelmanns, Christine;* Kim, Ki Hyun.* Polyhalogenation of Isoflavonoids by the Termite-Associated Actinomadura sp. RB99. J. Nat. Prod. 2020, 83, 3102–3110.
Lee, Seoung Rak; Kang, Heesun; Yoo, Min Jeong; Yu, Jae Sik; Lee, Seulah; Yi, Sang Ah; Beemelmanns, Christine; Lee, Jaecheol; Kim, Ki Hyun.* Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67. Nat. Prod. Sci. 2020, 26, 230-235.
Lee, Seoung Rak; Choi, Jin Hee; Ryoo, Rhim; Kim, Jin-Chul; Pang, Changhyun; Kim, Seon-Hee; and Kim, Ki Hyun.* Ergostane-Type Steroids from Korean Wild Mushroom Xerula furfuracea that Control Adipocyte and Osteoblast Differentiation. J. Microbiol. Biotechnol. 2020, 30, 1769–1776.
Yu, Jae Sik; Sahar, Namood E; Bi, Yan-Ran; Jung, Kiwon; Pang, Changhyun; Huh, Joo Young;* Kim, Ki Hyun.* The Effects of Triterpenoid Saponins from the Seeds of Momordica cochinchinensis on Adipocyte Differentiation and Mature Adipocyte Inflammation. Plants 2020, 9, 984.
Baek, Su Cheol; Lee, Bum Soo; Yi, Sang Ah; Lee, Jaecheol; Kim, Ki Hyun.* Carthamusuchuric acid, an enolic glucoside of phenylpyruvic acid from the florets of Carthamus tinctorius and anti-adipogenic phenolic compounds. Tetrahedron Lett. 2020, 61, 152237.
Thapa, Punam; Gu, Ye; Kil, Yun-Seo; Baek, Su Cheol; Kim, Ki Hyun; Han, Ah-Reum; Seo, Eun Kyoung; Choi, Hyukjae; Chang, Jae-Hoon; Nam, Joo-Won.* N-Acetyldopamine Derivatives from Periostracum Cicadae and Their Regulatory Activities on Th1 and Th17 Cell Differentiation. Bioorg. Chem. 2020, 102, 104095.
Baek, Su Cheol; Lee, Bum Soo; Yi, Sang Ah; Yu, Jae Sik; Lee, Jaecheol; Ko, Yoon-Joo; Pang, Changhyun;* Kim, Ki Hyun.* Discovery of Dihydrophaseic Acid Glucosides from the Florets of Carthamus tinctorius. Plants 2020, 9, 858.
Ha, Ji Won; Kim, Juhui; Kim, Hyunwoo; Jang, Wonyoung; Kim, Ki Hyun.* Mushrooms: An Important Source of Natural Bioactive Compounds. Nat. Prod. Sci. 2020, 26, 118-131.
Yu, Jae Sik; Park, Minji; Pang, Changhyun; Rashan, Luay; Jung, Won Hee; Kim, Ki Hyun.* Antifungal Phenols from Woodfordia uniflora Collected in Oman. J. Nat. Prod. 2020, 83, 2261−2268.
Lee, Seoung Rak; Lee, Dahae; Lee, Bum Soo; Ryoo, Rhim; Pang, Changhyun; Kang, Ki Sung; Kim, Ki Hyun.* Phallac acids A and B, new sesquiterpenes from the fruiting bodies of Phallus luteus. J. Antibiot. 2020, 73, 729-732.
Lee, Seul; Woo, Dong-Cheol; Kang, Jeeheon; Ra, Moonjin; Kim, Ki Hyun; Lee, Seoung Rak; Choi, Dong Kyu; Lee, Heejin; Hong, Ki Bum; Min, Sang-Hyun; Lee, Yongjun;* Yu, Ji Hoon.* The role of the Histone Methyltransferase EZH2 in Liver Inflammation and Fibrosis in STAM NASH Mice. Biology 2020, 9, 93.
Lee, Dahae;† Lee, Yong Hoon;† Lee, Kwang Ho;† Lee, Bum Soo; Alishir, Akida; Ko, Yoon-Joo; Kang, Ki Sung;* Kim, Ki Hyun.* Aviculin Isolated from Lespedeza cuneata Induce Apoptosis in Breast Cancer Cells through Mitochondria-Mediated Caspase Activation Pathway. Molecules 2020, 25, 1708.
Lee, Dahae; Choi, Sungyoul; Yamabe, Noriko; Kim, Ki Hyun;*, Kang, Ki Sung.* Recent Findings on the Mechanism of Cisplatin-Induced Renal Cytotoxicity. Nat. Prod. Sci. 2020, 26, 28-49.
Lee, Seoung Rak; Kreuzenbeck, Nina B.; Jang, Mina; Oh, Taehoon; Ko, Sung-Kyun; Ahn, Jong Seog; Beemelmanns, Christine; Kim, Ki Hyun.* Xyloneside A: a new glycosylated incisterol derivative from Xylaria sp. FB. ChemBioChem 2020, 21, 2253-2258.
Kim, Yong-Goo; Komakech, Richard; Jeong, Dae Hui; Park, Yun Mi; Lee, Tae Kyoung; Kim, Ki Hyun; Lee, A Yeong; Moon, Byeong Cheol; Kang, Youngmin.* Verification of the Field Productivity of Rehmannia glutinosa (Gaertn.) DC. Developed Through Optimized In Vitro Culture Method. Plants 2020, 9, 317.
Lee, Dahae;† Kang, Kyo Bin;† Kim, Hyun Woo; Park, Jung Sik; Hwang, Gwi Seo; Kang, Ki Sung; Choi, Sungyoul; Yamabe, Noriko;* Kim, Ki Hyun.* Unique Triterpenoid of Jujube Root Protects Cisplatin-induced Damage in Kidney Epithelial LLC-PK1 Cells via Autophagy Regulation. Nutrients 2020, 12, 677.
Jo, Mun Seok; Lee, Seoyoung; Yu, Jae Sik; Baek, Su Cheol; Cho, Young-Chang; Kim, Ki Hyun.* Megastigmane Derivatives from the Cladodes of Opuntia humifusa and Their Nitric Oxide Inhibitory Activities in Macrophages. J. Nat. Prod. 2020, 83, 684−692.
Lee, Seulah; Kim, Min-Ji; Lee, Bum Soo; Ryoo, Rhim; Kim, Hye Kyung;* Kim, Ki Hyun.* Cumulative effects of constituents from the mushroom Calvatia nipponica on the contractility of penile corpus cavernosum smooth muscle. Mycobiology 2020, 48, 153−156.
Baek, Su Cheol;† Lee, Dahae;† Jo, Mun Seok; Lee, Kwang Ho; Lee, Yong Hoon; Kang, Ki Sung; Yamabe, Noriko;* Kim, Ki Hyun.* Inhibitory Effect of 1,5-Dimethyl Citrate from Sea Buckthorn (Hippophae rhamnoides) on Lipopolysaccharide-induced Inflammatory Response in RAW 264.7 Mouse Macrophages. Foods 2020, 9, 269.
Babaie, Soraya; Rahmani Del Bakhshayesh, Azizeh; Ha, Ji Won; Hamishehkar, Hamed;* Kim, Ki Hyun.* Invasome: A Novel Nanocarrier for Transdermal Drug Delivery. Nanomaterials 2020, 10, 341.
Lee, Seulah; Ryoo, Rhim; Choi, Jin Hee; Kim, Jeong-Han; Kim, Seon-Hee; Kim, Ki Hyun.* Trichothecene and tremulane sesquiterpenes from a hallucinogenic mushroom Gymnopilus junonius and their cytotoxicity. Arch. Pharm. Res. 2020, 43, 214–223.
Lee, Dahae; Lee, Seoung Rak; Kang, Ki Sung;* Kim, Ki Hyun.* Benzyl salicylate from the stems and stem barks of Cornus walteri as a nephroprotective agent against cisplatin-induced apoptotic cell death in LLC-PK1 cells. RSC Adv. 2020, 10, 5777-5784.
Lee, Seoung Rak; Lee, Dahae; Park, Musun; Lee, Joo Chan; Park, Hyun-Ju; Kang, Ki Sung; Kim, Chang-Eop; Beemelmanns, Christine; Kim, Ki Hyun.* Absolute Configuration and Corrected NMR Assignment of 17-Hydroxycyclooctatin, a Fused 5-8-5 Tricyclic Diterpene. J. Nat. Prod. 2020, 83, 354-361.
Lee, Seoung Rak; Yi, Sang Ah; Nam, Ki Hong; Park, Jae Gyu; Hwang, Jae Sam; Lee, Jaecheol; Kim, Ki Hyun.* (±)-Kituramides A and B, pairs of enantiomeric dopamine dimers from the two-spotted cricket Gryllus bimaculatus. Bioorg. Chem. 2020, 95, 103554.
Kang, Min Cheol;† Yumnam, Silvia;† Park, Woo Sung; So, Hae Min; Kim, Ki Hyun; Shin, Meong Cheol; Ahn, Mi-Jeong; Kim, Sun Yeou.* Ulmus parvifolia Accelerates Skin Wound Healing by Regulating the Expression of MMPs and TGF-
β. J. Clin. Med. 2020, 9, 59.
Yi, Sang Ah;† Nam, Ki Hong;† Kim, Sil; So, Hae Min; Ryoo, Rhim; Han, Jeung-Whan; Kim, Ki Hyun;* Lee, Jaecheol.* Vulpinic Acid Controls Stem Cell Fate toward Osteogenesis and Adipogenesis. Genes 2020, 11, 18.
Park, Yong Joo;† Kim, Dong Min;† Jeong, Mi Ho; Yu, Jae Sik; So, Hae Min; Bang, In Jae; Kim, Ha Ryong; Kwon, Seung-Hwan; Kim, Ki Hyun;* Chung, Kyu Hyuck.* (-)-Catechin-7-O-β-D-Apiofuranoside Inhibits Hepatic Stellate Cells Activation by Suppressing STAT3 Signaling Pathway. Cells 2020, 9, 30.
Kim, Yong-Goo; Komakech, Richard; Choi, Ji Eun; Lee, Ka Youn; Lee, Tae Kyoung; Kim, Ki Hyun; Moon, Byeong Cheol; Kim, Suk Won; Kang, Youngmin.* Mass production of Pinellia ternata multiple egg-shaped micro-tubers (MESMT) through optimized growth conditions for use in ethnomedicine. Plant Cell Tiss. Organ Cult. 2020, 140, 173–184.
Lee, Seoung Rak; Yi, Sang Ah; Nam, Ki Hong; Ryoo, Rhim; Lee, Jaecheol; Kim, Ki Hyun.* Pantheric acids A-C from a Poisonous Mushroom, Amanita pantherina Promote Lipid Accumulation in Adipocytes. J. Nat. Prod. 2019, 82, 3489-3493.
Baek, Su Cheol;† Nam, Ki Hong;† Yi, Sang Ah;† Jo, Mun Seok; Lee, Kwang Ho; Lee, Yong Hoon; Lee, Jaecheol;* Kim, Ki Hyun.* Anti-adipogenic Effect of β-Carboline Alkaloids from Garlic (Allium sativum). Foods 2019, 8, 673.
Baek, Su Cheol; Lee, Seoyoung; Kim, Sil; Jo, Mun Seok; Yu, Jae Sik; Ko, Yoon-Joo; Cho, Young-Chang; Kim, Ki Hyun.* Withaninsams A and B: Phenylpropanoid Esters from the Roots of Indian Ginseng (Withania somnifera). Plants 2019, 8, 527.
Kwon, Seung-Hwan; Lee, Seoung Rak; Park, Yong Joo; Ra, Moonjin; Lee, Yongjun; Pang, Changhyun;* Kim, Ki Hyun.* Suppression of 6-Hydroxydopamine-induced Oxidative Stress by Hyperoside via Activation of Nrf2/HO-1 Signaling in Dopaminergic Neurons. Int. J. Mol. Sci. 2019, 20, 5832.
Jo, Mun Seok; Yu, Jae Sik; Lee, Joo Chan; Lee, Seoyoung; Cho, Young-Chang; Park, Hyun-Ju; Kim, Ki Hyun.* Lobatamunsolides A-C, Norlignans from the Roots of Pueraria lobata and their Nitric Oxide Inhibitory Activities in Macrophages. Biomolecules 2019, 9, 755.
Lee, Seulah;† Lee, Dahae;† Baek, Su Cheol; Jo, Mun Seok; Kang, Ki Sung;* Kim, Ki Hyun.* (3β,16α)-3,16-Dihydroxypregn-5-en-20-one from the Twigs of Euonymus alatus (Thunb.) Sieb. Exerts Anti-Inflammatory Effects in LPS-Stimulated RAW-264.7 Macrophages. Molecules 2019, 24, 3848.
Lee, Seoung Rak; Lee, Dahae; Eom, Hee Jeong; Rischer, Maja; Ko, Yoon-Joo; Kang, Ki Sung; Kim, Chung Sub; Beemelmanns, Christine;* Kim, Ki Hyun.* Hybrid Polyketides from a Hydractinia-Associated Cladosporium sphaerospermum SW67 and Their Putative Biosynthetic Origin. Mar. Drugs 2019, 17, 606.
Lee, Seulah; Lee, Joo Chan; Subedi, Lalita; Cho, Kyo Hee; Kim, Sun Yeou; Park, Hyun-Ju; Kim, Ki Hyun.* Bioactive compounds from the seeds of Amomum tsaoko Crevost et Lemaire, a Chinese spice as inhibitors of sphingosine kinases, SPHK1/2. RSC Adv. 2019, 9, 33957-33968.
Ghaffari, Tayyebeh; Kafil, Hossein Samadi; Asnaashari, Solmaz; Farajnia, Safar; Delazar, Abbas; Baek, Su Cheol; Hamishehkar, Hamed;* Kim, Ki Hyun.* Chemical Composition and Antimicrobial Activity of Essential Oils from the Aerial Parts of Pinus eldarica Grown in Northwestern Iran. Molecules 2019, 24, 3203.
Song, Ji Hoon; Kim, Sil; Yu, Jae Sik; Park, Do Hwi; Kim, Song-Yi; Kang, Ki Sung; Lee, Sullim;* Kim, Ki Hyun.* Procyanidin B2 3′′-O-gallate Isolated from Reynoutria elliptica Prevents Glutamate-Induced HT22 Cell Death by Blocking the Accumulation of Intracellular Reactive Oxygen Species. Biomolecules 2019, 9, 412.
Klassen, Jonathan L.; Lee, Seoung Rak; Poulsen, Michael; Beemelmanns, Christine;* Kim, Ki Hyun.* Efomycins K and L from a termite-associated Streptomyces sp. M56 and their putative biosynthetic origin. Front. Microbiol. 2019, 10, 1739.
So, Hae Min; Yu, Jae Sik; Khan, Zarha; Subedi, Lalita; Ko, Yoon-Joo; Lee, Il Kyun; Park, Woo Sung; Chung, Sang J.; Ahn, Mi-Jeong; Kim, Sun Yeou; Kim, Ki Hyun.* Chemical constituents of the root bark of Ulmus davidiana var. japonica and their potential biological activities. Bioorg. Chem. 2019, 91, 103145.
Lee, Dahae; Lee, Seoung Rak; Kang, Ki Sung; Ko, Yuri; Pang, Changhyun; Yamabe, Noriko;* Kim, Ki Hyun.* Betulinic Acid Suppresses Ovarian Cancer Cell Proliferation through Induction of Apoptosis. Biomolecules 2019, 9, 257.
Jin, Yan; Zhao, Jing; Kim, Eun Mi; Kim, Ki Hyun; Kang, Seulgi; Lee, Heesoo; Lee, Jeongmi.* Comprehensive Investigation of the Effects of Brewing Conditions in Sample Preparation of Green Tea Infusions. Molecules 2019, 24, 1735.
Lee, Tae Kyoung; Lee, Dahae; Lee, Seoung Rak; Ko, Yoon-Joo; Kang, Ki Sung; Chung, Sang Jeon; Kim, Ki Hyun.* Sesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells. Bioorg. Chem. 2019, 87, 117-122.
Yoon, Sun-Young;† Lee, Seoung Rak;† Hwang, Ji Young; Benndorf, René; Beemelmanns, Christine; Chung, Sang J.;* Kim, Ki Hyun.* Fridamycin A, a Microbial Natural Product, Stimulates Glucose Uptake without Inducing Adipogenesis. Nutrients 2019, 11, 765.
Trinh, Tuy An; Park, Eun-Ji; Lee, Dahae; Song, Ji Hoon; Lee, Hye Lim; Kim, Ki Hyun; Kim, Younghoon; Jung, Kiwon; Kang, Ki Sung;* Yoo, Jung-Eun.* Estrogenic Activity of Sanguiin H-6 through Activation of Estrogen Receptor α Coactivator-binding Site. Nat. Prod. Sci. 2019, 25, 28-33.
Lee, Dahae;† Kim, Ki Hyun;† Lee, Won Yung; Kim, Chang-Eop; Sung, Sang Hyun; Kang, Kyo Bin;* Kang, Ki Sung.* Multiple Targets of 3-dehydroxyceanothetric Acid 2-methyl Ester to Protect Cisplatin-Induced Cytotoxicity in Kidney Epithelial LLC-PK1 Cells. Molecules 2019, 24, 878. †contributed equally
232. Kim, Sil; Yu, Jae Sik; Lee, Ji Young; Choi, Sang Un; Lee, Jeongmi; Kim, Ki Hyun.* Cytotoxic Withanolides from the Roots of Indian Ginseng (Withania somnifera). J. Nat. Prod. 2019, 82, 765−773.
231. Kim, Da Wan; Baik, Sangyul; Min, Hyeongho; Chun, Sungwoo; Lee, Heon Joon; Kim, Ki Hyun; Lee, Jun Young; Pang, Changhyun.* Highly permeable skin patch with conductive hierarchical architectures inspired by amphibians and octopi for omnidirectionally enhanced wet adhesion. Adv. Funct. Mater. 2019, 29, 1807614.
230. Jo, Beom-Geun;‡ Park, No-June;‡ Kim, Su-Nam; Jegal, Jonghwan; Choi, Sangho; Lee, Sang Woo; Yi, Li Wan; Lee, Seoung Rak; Kim, Ki Hyun;* Yang, Min Hye.* Isolation of maltol derivatives from Stellera chamaejasme and the anti-atopic properties of maltol on skin lesions in DNCB-stimulated mice. RSC Adv. 2019, 9, 2125–2132.
229. Rischera, Maja; # Lee, Seoung Rak;# Eom, Hee Jeong; Park, Hyun Bong; Vollmers, John; Kaster, Anne-Kristin; Shin, Yern-Hyerk; Oh, Dong-Chan; Kim, Ki Hyun;* Beemelmanns, Christine.* Spirocyclic cladosporicin A and cladosporiumins I and J from a Hydractinia-associated Cladosporium sphaerospermum SW67. Org. Chem. Front. 2019, 6, 1084–1093.
228. Lee, Seoung Rak; Seok, Soonja; Ryoo, Rhim; Choi, Sang Un; Kim, Ki Hyun.* Macrocyclic Trichothecene Mycotoxins from a Deadly Poisonous Mushroom Podostroma cornu-damae. J. Nat. Prod. 2019, 82, 122-128.
227. Lee, Seoung Rak; Küfner, Michelle; Park, Minji; Jung, Won Hee; Choi, Sang Un; Beemelmanns, Christine; Kim, Ki Hyun.* Beauvetetraones A-C, phomaligadione-derived polyketide dimers from the entomopathogenic fungus, Beauveria bassiana. Org. Chem. Front. 2019, 6, 162-166.
226. Strandwitz, Philip;1 Kim, Ki Hyun;1 Terekhova, Darya; Liu, Joanne K.; Sharma, Anukriti; Levering, Jennifer; McDonald, Daniel; Dietrich, David; Ramadhar, Timothy R.; Lekbua, Asama; Mroue, Nader; Liston, Conor; Stewart, Eric J.; Dubin, Marc J.; Zengler, Karsten; Knight, Rob; Gilbert, Jack A.; Clardy, Jon; Lewis, Kim. GABA Modulating Bacteria of the Human Gut Microbiota. Nat. Microbiol. 2019, 4, 396–403.
225. Ahn, Soo-Yeon;1 Jo, Mun Seok;1 Lee, Dahae;1 Baek, Seon-Eun; Baek, Jiwon; Yu, Jae Sik; Jo, Jeyun; Yun, Hwayoung; Kang, Ki Sung; Yoo, Jeong-Eun;* Kim, Ki Hyun.* Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells. Bioorg. Chem. 2019, 83, 135-144.
224. Lee, Tae Kyoung;1 Trinh, Tuy An;1 Lee, Seoung Rak; Kim, Sil; So, Hae Min; Moon, Eunjung; Hwang, Gwi Seo; Kang, Ki Sung; Kim, Ji Hwan; Yamabe, Noriko;* Kim, Ki Hyun.* Bioactivity-based analysis and chemical characterization of anti-inflammatory compounds from Curcuma zedoaria rhizomes using LPS-stimulated RAW264.7 cells. Bioorg. Chem. 2019, 82, 26-32.
223. Lee, Seoung Rak; Park, Yong Joo; Han, Yu Bin; Lee, Joo Chan; Lee, Seulah; Park, Hyun-Ju; Lee, Hae-Jeung;* Kim, Ki Hyun.* Isoamericanoic Acid B from Acer tegmentosum as a Potential Phytoestrogen. Nutrients 2018, 10, 1915.
222. Lee, Seoung Rak; Lee, Dahae; Yu, Jae Sik; Benndorf, René; Lee, Sullim; Lee, Dong-Soo; Huh, Jungmoo; de Beer, Z. Wilhelm; Kim, Yong Ho; Beemelmanns, Christine; Kang, Ki Sung; Kim, Ki Hyun.* Natalenamides A-C, Cyclic Tripeptides from the Termite-associated Actinomadura sp. RB99. Molecules 2018, 23, 3003.
221. Lee, Seoung Rak; Park, Hyun Bong; Kim, Ki Hyun.* Highly sensitive, simple, and cost/time-effective method to determine the absolute configuration of a secondary alcohol using competing enantioselective acylation coupled with LC/MS. Anal. Chem. 2018, 90, 13212-13216.
220. Lee, Seoung Rak; Choi, Eunyong; Jeon, Se Hun; Zhi, Xue Yan; Yu, Jae Sik; Kim, Seon-Hee; Lee, Jeongmi; Park, Ki-Moon; Kim, Ki Hyun.* Tirucallane Triterpenoids from the Stems and Stem Bark of Cornus walteri that Control Adipocyte and Osteoblast Differentiations. Molecules 2018, 23, 2732.
219. Park, Yong Joo;† Lee, Seoung Rak;† Kim, Dong Min; Yu, Jae Sik; Beemelmanns, Christine; Chung, Kyu Hyuck; Kim, Ki Hyun.* The Inhibitory Effects of Cyclodepsipeptides from the Entomopathogenic Fungus Beauveria bassiana on Myofibroblast Differentiation in A549 Alveolar Epithelial Cells. Molecules 2018, 23, 2568.
218. Lee, Seulah;† Lee, Seul;† Roh, Hyun-Soo; Song, Seong-Soo; Ryoo, Rhim; Pang, Changhyun; Baek, Kwan-Hyuck;* Kim, Ki Hyun.* Cytotoxic Constituents from the Sclerotia of Poria cocos against Human Lung Adenocarcinoma Cells by Inducing Mitochondrial Apoptosis. Cells 2018, 7, 116.
217. Lee, Tae Kyoung; Lee, Dahae; Yu, Jae Sik; Jo, Mun Seok; Baek, Su Cheol; Shin, Myoung-Sook; Ko, Yoon-Joo; Kang, Ki Sung;* Kim, Ki Hyun.* Biological Evaluation of a New Lignan from the Roots of Rice (Oryza sativa). Chem. Biodivers. 2018, 15, e1800333.
216. Lee, Seoung Rak;† Song, Ji Hoon;† Song, Jae-Hyoung; Ko, Hyun-Jeong; Baek, Ji Yun; Trinh, Tuy An; Beemelmanns, Christine; Yamabe, Noriko;* Kim, Ki Hyun.* Chemical Identification of Isoflavonoids from a Termite-Associated Streptomyces sp. RB1 and Their Neuroprotective Effects in Murine Hippocampal HT22 Cell Line. Int. J. Mol. Sci. 2018, 19, 2640.
215. So, Hae Min; Eom, Hee Jeong; Lee, Dahae; Kim, Sil; Kang, Ki Sung; Lee, Il Kyun; Baek, Kwan-Hyuck; Park, Jun Yeon; Kim, Ki Hyun.* Bioactivity evaluations of betulin identified from the bark of Betula platyphylla var. japonica for cancer therapy. Arch. Pharm. Res. 2018, 41, 815–822.
214. Lee, Seulah; Choi, Eunyong; Yang, Su-Man; Ryoo, Rhim; Moon, Eunjung; Kim, Seon-Hee; Kim, Ki Hyun.* Bioactive compounds from sclerotia extract of Poria cocos that control adipocyte and osteoblast differentiation. Bioorg. Chem. 2018, 81, 27-34.
213. Baek, Jiwon; Lee, Tae Kyoung; Song, Jae-Hyoung; Choi, Enuyong; Ko, Hyun-Jeong; Lee, Sanghyun; Choi, Sang Un; Lee, Seong; Yoo, Sang-Woo; Kim, Seon-Hee; Kim, Ki Hyun.* Lignan Glycosides and Flavonoid Glycosides from the Aerial Portion of Lespedeza cuneata and their Biological Evaluations. Molecules 2018, 23, 1920.
212. Baek, Su Cheol; Choi, Enuyong; Eom, Hee Jeong; Jo, Mun Seok; Kim, Sil; So, Hae Min; Kim, Seon-Hee; Kang, Ki Sung;* Kim, Ki Hyun.* LC/MS-based analysis of bioactive compounds from the bark of Betula platyphylla var. japonica and their effects on regulation of adipocyte and osteoblast differentiation. Nat. Prod. Sci. 2018, in press.
211. Huh, Joo Young;1 Lee, Seulah;1 Ma, Eun-Bi; Eom, Hee Jeong; Baek, Jiwon; Ko, Yoon-Joo; Kim, Ki Hyun.* The effects of phenolic glycosides from Betula platyphylla var. japonica on adipocyte differentiation and mature adipocyte metabolism. J. Enzyme Inhib. Med. Chem. 2018, 33, 1167–1173.
210. Lee, Seulah; Lee, Dahae; Lee, Joo Chan; Kang, Ki Sung; Ryoo, Rhim; Park, Hyun-Ju; Kim, Ki Hyun.* Bioactivity-guided Isolation of Anti-inflammatory Constituents of the Rare Mushroom Calvatia nipponica in LPS-stimulated RAW264.7 Macrophages. Chem. Biodivers. 2018, 15, e1800203.
209. Baek, Jiwon;1 Roh, Hyun-Soo;1 Baek, Kwan-Hyuck;1 Lee, Seulah; Lee, Seul; Song, Seong-Soo; Kim, Ki Hyun.* Bioactivity-based analysis and chemical characterization of cytotoxic constituents from Chaga mushroom (Inonotus obliquus) that induce apoptosis in human lung adenocarcinoma cells. J. Ethnopharmacol. 2018, 224, 63-75.
208. Lee, Tae Kyoung; Kang, Hee Rae; Kim, Ki Hyun.* A new feruloyl glyceride from the roots of Asian rice (Oryza sativa). Rev. Bras. Farmacogn. 2018, 28, 421-424.
207. Lee, Dahae; Yu, Jae Sik; Lee, Seoung Rak; Hwang, Gwi Seo; Kang, Ki Sung; Park, Jae Gyu; Kim, Hyun Young; Kim, Ki Hyun,* Yamabe, Noriko.* Beneficial effects of bioactive compounds in mulberry fruits against anticancer drug-induced nephrotoxicity. Int. J. Mol. Sci. 2018, 19, 1117.
206. Kang, Hee Rae; Yun, Hyung Sik; Lee, Tae Kyoung; Lee, Seulah; Kim, Seon-Hee; Moon, Eunjung; Park, Ki-Moon; Kim, Ki Hyun.* Chemical Characterization of Novel Natural Products from the Roots of Asian Rice (Oryza sativa) that Control Adipocyte and Osteoblast Differentiation. J. Agric. Food Chem. 2018, 66, 2677-2684.
205. Yu, Jae Sik; Roh, Hyun-Soo; Baek, Kwan-Hyuck; Lee, Seul; Kim, Sil; So, Hae Min; Moon, Eunjung; Pang, Changhyun; Jang, Tae Su; Kim, Ki Hyun.* Bioactivity-guided isolation of ginsenosides from Korean Red Ginseng with cytotoxic activity against human lung adenocarcinoma cells. J. Ginseng Res. 2018, in press.
204. Lee, Tae Kyoung; Park, Jun Yeon; Yu, Jae Sik; Jang, Tae Su; Oh, Seong Taek; Pang, Changhyun; Ko, Yoon-Joo; Kang, Ki Sung;* Kim, Ki Hyun.* 7α,15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs. Bioorg. Med. Chem. Lett. 2018, 28, 1084-1089.
203. Lee, Seulah; Lee, Dahae; Park, Jun Yeon; Seok, Soonja; Jang, Tae Su; Park, Hyun Bong; Shim, Sang Hee; Kang, Ki Sung;* Kim, Ki Hyun.* Anti-gastritis effects of Armillariella tabescens (Scop.) Sing. and the identification of its anti-inflammatory metabolites. J. Pharm. Pharmacol. 2018, 70, 404–412.
202. Song, Ji Hoon; Lee, Dahae; Lee, Seoung Rak; Yu, Jae Sik, Jang, Tae Su; Nam, Joo-Won; Kim, Ki Hyun;* Kang, Ki Sung.* Identification of bioactive heterocyclic compounds from mulberry and their protective effect against streptozotocin-induced apoptosis in INS-1 cells. Mol. Med. Rep. 2018, 17, 5982–5987.
201. Kim, Ki Hyun;☆ Lee, Dahae;☆ Lee, Hye Lim; Kim, Chang-Eop; Jung, Kiwon;* Kang, Ki Sung.* Beneficial effects of Panax ginseng for the treatment and prevention of neurodegenerative diseases: past findings and future directions. J. Ginseng Res. 2018, 42, 239-247.
200. Jung, Eun Bee; Trinha, Tuy An; Lee, Tae Kyoung; Yamabe, Noriko; Kang, Ki Sung; Song, Ji Hoon; Choi, Sungyoul; Lee, Sanghyun, Jang, Tae Su; Kim, Ki Hyun;* Hwang, Gwi Seo.* Curcuzedoalide contributes to the cytotoxicity of Curcuma zedoaria rhizomes against human gastric cancer AGS cells through induction of apoptosis. J. Ethnopharmacol. 2018, 213, 48-55.
199. Baek, Jiwon; Lee, Dahae; Lee, Tae Kyoung; Song, Ji Hoon; Lee, Ju Sung; Lee, Seong; Yoo, Sang-Woo; Kang, Ki Sung; Moon, Eunjung; Lee, Sanghyun,* Kim, Ki Hyun.* (−)-9′-O-(α-L-Rhamnopyranosyl)lyoniresinol from Lespedeza cuneata suppresses ovarian cancer cell proliferation through induction of apoptosis. Bioorg. Med. Chem. Lett. 2018, 28, 122–128.
198. Lee, Seoung Rak; Roh, Hyun-Soo; Lee, Seul; Park, Hyun Bong; Jang, Tae Su; Ko, Yoon-Joo; Baek, Kwan-Hyuck;* Kim, Ki Hyun.* Bioactivity-guided isolation and chemical characterization of antiproliferative constituents from Morel mushroom (Morchella esculenta) in human lung adenocarcinoma cells. J. Funct. Foods 2018, 40, 249–260.
197. Lee, Dahae; Kang, Ki Sung; Lee, Hae-Jeung,* Kim, Ki Hyun.* Chemical characterization of a renoprotective metabolite from termite-associated Streptomyces sp. RB1 against cisplatin-induced cytotoxicity. Int. J. Mol. Sci. 2018, 19, E174.
196. Lee, Dahae; Lee, Dong-Soo; Jung, Kiwon; Hwang, Gwi Seo; Lee, Hye Lim; Yamabe, Noriko; Lee, Hae-Jeong; Eom, Dae-Woon; Kim, Ki Hyun;* Kang, Ki Sung.* Protective effect of ginsenoside Rb1 against tacrolimus-induced nephrotoxicity in renal proximal tubular LLC-PK1 cells. J. Ginseng Res. 2018, 42, 75-80.
194. Yu, Jae Sik; Lee, Dahae; Lee, Seoung Rak; Lee, Jae Wook; Choi, Chang-Ik; Jang, Tae Su; Kang, Ki Sung; Kim, Ki Hyun.* Chemical characterization of cytotoxic indole acetic acid derivative from Mulberry fruit (Morus alba L.) against human cervical cancer. Bioorg. Chem. 2018, 76, 28-36.
194. Lee, Seulah; Lee, Dahae; Baek, Jiwon; Jung, Eun Bee; Baek, Ji Yun; Lee, Il Kyun; Jang, Tae Su; Kang, Ki Sung,* Kim, Ki Hyun.* In vitro assessment of selected Korean plants for antioxidant and anti-acetylcholinesterase activities. Pharm. Biol. 2017, 55, 2205-2210.
193. Lee, Yongjun; Kwon, Dong-Joo, Kim, Young Han; Ra, Moonjin; Heo, Seong Il; Ahn, Won Gyeong; Park, Jeong-Ran; Lee, Seoung Rak; Kim, Ki Hyun; Kim, Sun Young. HIMH0021 attenuates ethanol-induced liver injury and steatosis in mice. PLoS ONE 2017, 12, e0185134.
192. Huh, Jungmoo; Ha, Thi Kim Quy; Kang, Kyo Bin; Kim, Ki Hyun; Oh, Won Keun; Kim, Jinwoong; Sung, Sang Hyun. C-Methylated Flavonoid Glycosides from Pentarhizidium orientale Rhizomes and Their Inhibitory Effects on the H1N1 Influenza Virus. J. Nat. Prod. 2017, 80, 2818-2824.
191. Lee, Seulah; Lee, Dahae; Jang, Tae Su; Kang, Ki Sung; Nam, Joo-Won; Lee, Hae-Jeung; Kim, Ki Hyun.* Anti-inflammatory Phenolic Metabolites from the Edible Fungus Phellinus baumii in LPS-stimulated RAW264.7 Cells. Molecules 2017, 22, 1583.
190. Lee, Sang-Jin; Vuong, Tuan Anh; Go, Ga-Yeon; Song, Yoo-Jin; Lee, Seulah; Lee, Soo-Yeon; Kim, Shin-Woong; Lee, Jaecheol; Kim, Yong Kee; Seo, Dong-Wan; Kim, Ki Hyun; Kang, Jong-Sun; Bae, Gyu-Un. An isoflavone compound daidzein elicits myoblast differentiation and myotube growth. J. Funct. Foods 2017, 38, 438-446.
189. Woo, Kyeong Wan; Park, Kyoung Jin; Choi, Sang Zin; Son, Mi Won; Kim, Ki Hyun; Lee, Kang Ro.* A new ent-kaurane diterpene glycoside from seeds of Pharbitis nil. Chem. Nat. Compd. 2017, 53, 468-471.
188. Park, Eun-Ji; Lee, Dahae; Baek, Seon-Eun; Kim, Ki Hyun; Kang, Ki Sung; Jang, Tae Su; Lee, Hye Lim; Song, Ji Hoon; Yoo, Jung-Eun. Cytotoxic effect of sanguiin H-6 on MCF-7 and MDA-MB-231 human breast carcinoma cells. Bioorg. Med. Chem. Lett. 2017, in press.
187. Yu, Jae Sik; Moon, Eunjung; Kim, Ki Hyun.* A new cerebroside from the twigs of Lindera glauca (Sieb. et Zucc.) Blume. Bioorg. Chem. 2017, 74, 122-125.
186. Lee, Seulah;1 Park, Jun Yeon;1 Lee, Dahae; Seok, Soonja; Kwon, Yeon Jung; Jang, Tae Su; Kang, Ki Sung; Kim, Ki Hyun.* Chemical constituents from the rare mushroom Calvatia nipponica inhibit the promotion of angiogenesis in HUVECs. Bioorg. Med. Chem. Lett. 2017, 27, 4122-4127.
185. Kim, Sil;1 So, Hae Min;1 Roh, Hyun-Soo;1 Kim, Jin; Yu, Jae Sik; Lee, Seul; Seok, Soonja; Pang, Changhyun; Baek, Kwan-Hyuck;* Kim, Ki Hyun Kim.* Vulpinic acid contributes to the cytotoxicity of Pulveroboletus ravenelii to human cancer cells by inducing apoptosis. RSC Adv. 2017, 7, 35297–35304.
184. Shin, Seung Ho; 1 Lee, Seoung Rak; 1 Lee, Eunjung; Kim, Ki Hyun;* Byun, Sanguine.* Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c‑Fos Degradation. J. Nat. Prod. 2017, 80, 2124–2130.
183. Mun, Bohyun; Kim, Sangyong; Yoon, Hongju; Kim, Ki Hyun; Lee, Yunmi. Total Synthesis of Isohericerin, Isohericenone, and Erinacerin A: Development of a Copper-Catalyzed Methylboronation of Terminal Alkyne. J. Org. Chem. 2017, 82, 6349−6357.
182. Lee, Seoung Rak; Nam, Joo-Won; Kim, Ki Hyun.* New Triterpenoids from the Stems of Cornus walteri. Chem. Pharm. Bull. 2017, 65, 683−686.
181. Lee, Dahae; Kim, Taejung; Kim, Ki Hyun; Ham, Jungyeob; Jang, Tae Su; Kang, Kisung; Lee, Jae Wook. Evaluation of guggulsterone derivatives as novel kidney cell protective agents against cisplatin-induced nephrotoxicity. Bioorg. Med. Chem. Lett. 2017, 27, 3156-3161.
180. Baek, Jiwon; Lee, Hye Lim; Kang, Ki Sung; Kim, Ki Hyun.* Chemical constituents from the fruits of Citrus unshiu and their inhibitory effects on acetylcholinesterase. Maced. J. Chem. Chem. En. 2017, 36, 15-22.
179. Lee, Dahae; Lee, Seulah; Shim, Sang Hee; Lee, Hae-Jeung; Choi, Youkyung; Jang, Tae Su; Kim, Ki Hyun;⁎ Kang, Ki Sung.⁎ Protective effect of lanostane triterpenoids from the sclerotia of Poria cocos Wolf against cisplatin-induced apoptosis in LLC-PK1 cells. Bioorg. Med. Chem. Lett. 2017, 27, 2881-2885.
178. Lee, Seoung Rak; Moo, Eunjung; Kim, Ki Hyun.* Neolignan and monoterpene glycoside from the seeds of Pharbitis nil. Phytochem. Lett. 2017, 20, 98-101.
177. Park, Jun Yeon; Lee, Yun Kyung; Lee, Dong-Soo; Yoo, Jeong-Eun; Shin, Myoung-Sook; Yamabe, Noriko; Kim, Su-Nam; Lee, Seulah; Kim, Ki Hyun; Lee, Hae-Jeung; Roh, Seok Sun; Kang, Ki Sung. Abietic acid isolated from pine resin (Resina Pini) enhances angiogenesis in HUVECs and accelerates cutaneous wound healing in mice. J. Ethnopharmacol. 2017, 203, 279-287.
176. Wyche, Thomas P.; Ruzzini, Antonio C.; Beemelmanns, Christine; Kim, Ki Hyun; Klassen, Jonathan L.; Cao, Shugeng; Poulsen, Michael; Bugni, Tim S.; Currie, Cameron R.; Clardy, Jon. Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides. Org. Lett. 2017, 19, 1772–1775.
175. Lee, Dahae;1 Kim, Ki Hyun;1 Hwang, Gwi Seo; Lee, Jaemin; Lee, Hye Lim; Hahm, Dae-hyun; Huh, Chang Ki; Lee, Sang Cheon; Lee, Sanghyun; Kang, Ki Sung. Protective effect of cirsimaritin against streptozotocin-induced apoptosis in pancreatic beta cells. J. Pharm. Pharmacol. 2017, 69, 875–883.
174. Yu, Jae Sik; Kim, Jun Ho; Lee, Seulah; Jung, Kiwon; Kim, Ki Hyun;* Cho, Jae Youl.* Src/Syk-Targeted Anti-Inflammatory Actions of Triterpenoidal Saponins from Gac (Momordica cochinchinensis) Seeds. Am. J. Chinese Med. 2017, 45, 459-473.
173. Yu, Jae Sik; Roh, Hyun-Soo; Lee, Seul; Jung, Kiwon; Baek, Kwan-Hyuck;* Kim, Ki Hyun.* Antiproliferative effect of Momordica cochinchinensis seeds on human lung cancer cells and isolation of the major constituents. Braz. J. Pharmacog. 2017, 27, 329–333.
172. Beemelmanns, Christine;% Ramadhar, Timothy R.;% Kim, Ki Hyun;% Klassen, Jonathan L.; Cao, Shugeng; Wyche, Thomas P.; Hou, Yanpeng; Poulsen, Michael; Bugni, Tim S.; Currie, Cameron R.; Clardy, Jon. Macrotermycins A−D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39. Org. Lett. 2017, 19, 1000–1003.
171. Lee, Seulah; Lee, Dahae; Lee, Sung Ok; Ryu, Ja-Young; Choi, Sang-Zin; Kang, Ki Sung; Kim, Ki Hyun.* Anti-inflammatory activity of the sclerotia of edible fungus, Poria cocos Wolf and their active lanostane triterpenoids. J. Funct. Foods 2017, 32, 27-36.
170. Lee, Seoung Rak; Lee, Dahae; Lee, Hae-Jeung; Noh, Hyung Jun; Jung, Kiwon; Kang, Ki Sung; Kim, Ki Hyun.* Renoprotective chemical constituents from an edible mushroom, Pleurotus cornucopiae in cisplatin-induced nephrotoxicity. Bioorg. Chem. 2017, 71, 67–73
169. Eom, Hee Jeong; Kang, Hee Rae; Choi, Sang Un; Kim, Ki Hyun.* Cytotoxic triterpenoids from the barks of Betula platyphylla var. japonica. Chem. Biodivers. 2017, 14, e1600400.
168. Lee, Tae Kyoung; Roh, Hyun-Soo; Yu, Jae Sik; Kwon, Dong-Joo; Kim, Sun Young; Baek, Kwan-Hyuck;* Kim, Ki Hyun.* A novel cytotoxic activity of the fruit of Sorbus commixta against human lung cancer cells and isolation of the major constituents. J. Funct. Foods 2017, 30, 1-7.
167. Baek, Jiwon; Roh, Hyun-Soo; Choi, Chang-Ik; Baek, Kwan-Hyuck;* Kim, Ki Hyun.* Raphanus sativus Sprout Causes Selective Cytotoxic Effect on p53-Deficient Human Lung Cancer Cells in vitro. Nat. Prod. Commun. 2017, 12, 237-240.
166. Lee, Tae Kyoung; Roh, Hyun-Soo; Yu, Jae Sik; Baek, Jiwon; Lee, Seul; Ra, Moonjin; Kim, Sun Young; Baek, Kwan-Hyuck;* Kim, Ki Hyun.* Pinecone of Pinus koraiensis Inducing Apoptosis in Human Lung Cancer Cells by Activating Caspase-3 and its Chemical Constituents. Chem. Biodivers. 2017, 14, e1600412.
165. Lee, Seoung Rak; Lee, Seulah; Moon, Eunjung; Park, Hye-Jin; Park, Hyun Bong; Kim, Ki Hyun.* Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells. Bioorg. Chem. 2017, 70, 94-99.
164. Park, Jun Yeon; Kwak, Jin Ho; Kang, Ki Sung; Jung, Eun Bee; Lee, Dong-Soo; Lee, Sanghyun; Jung, Yujung; Kim, Ki Hyun; Hwang, Gwi Seo; Lee, Hye Lim; Yamabe, Noriko; Kim, Su-Nam. Wound healing effects of deoxyshikonin isolated from Jawoongo: In vitro and in vivo studies. J. Ethnopharmacol. 2017, 199, 128-137.
163. Lee, Dahae; Kang, Ki Sung; Yu, Jae Sik; Woo, Jung-Yoon; Hwang, Gwi Seo; Eom, Dae-Woon; Baek, Seung-Hoon; Lee, Hye Lim; Kim, Ki Hyun;* Yamabe, Noriko*. Protective effect of Korean Red Ginseng against FK-506-induced damage in LLC-PK1 cells. J. Ginseng Res. 2017, 41, 284-289.
162. Segev , Einat; Wyche, Thomas P.; Kim, Ki Hyun; Petersen, Jörn; Ellebrandt, Claire; Vlamakis, Hera; Barteneva, Natasha; Paulson, Joseph N.; Chai, Liraz; Clardy, Jon; Kolter, Roberto. Dynamic metabolic exchange governs a marine algal-bacterial interaction. eLife 2016, 5, e17473.
161. Kang, Hee Rae; Lee, Dahae; Benndorf, René; Jung, Won Hee; Beemelmanns, Christine; Kang, Ki Sung; Kim, Ki Hyun.* Termisoflavones A–C, Isoflavonoid Glycosides from Termite-Associated Streptomyces sp. RB1. J. Nat. Prod. 2016, 79, 3072−3078.
160. Senger, Donald R.; Hoang, Mien V.; Kim, Ki Hyun; Li, Chunshun; Cao, Shugeng. Anti-inflammatory activity of Barleria lupulina: Identification of active compounds that activate the Nrf2 cell defense pathway, organize cortical actin, reduce stress fibers, and improve cell junctions in microvascular endothelial cells. J. Ethnopharmacol. 2016, 193, 397-407.
159. Mun, Bohyun; Park, Yong Joo; Sung, Gi Ho; Lee, Yunmi;* Kim, Ki Hyun.* Synthesis and antitumor activity of (‒)-bassianolide in MDA-MB 231 breast cancer cells through cell cycle arrest. Bioorg. Chem. 2016, 69, 64-70.
158. Eom, Hee Jeong; Lee, Dahae; Lee, Seulah; Noh, Hyung Jun; Hyun, Jae Wook; Yi, Pyoung Ho; Kang, Ki Sung; Kim, Ki Hyun.* Flavonoids and a Limonoid from the Fruits of Citrus unshiu and their Biological Activity. J. Agric. Food Chem. 2016, 64, 7171–7178..
157. Yu, Jae Sik; Baek, Jiwon; Park, Hyun Bong; Moon, Eunjung; Kim, Sun Yeou; Choi, Sang Un; Kim, Ki Hyun.* A new rearranged eudesmane sesquiterpene and bioactive sesquiterpenes from the twigs of Lindera glauca (Sieb. et Zucc.) Blume. Arch. Pharm. Res. 2016, 39, 1628–1634.
156. Byun, Sanguine; Shin, Seung Ho; Park, Jiman; Lim, Semi; Lee, Eunjung; Lee, Chaeyoon; Sung, Dongeun; Farrand, Lee; Lee, Seoung Rak; Kim, Ki Hyun; Dong, Zigang; Lee Sam W.; Lee, Ki Won. Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization. Mol. Nutr. Food Res. 2016, 60, 1068–1078.
155. Park, Yong Joo; Choi, Chang-Ik; Chung, Kyu Hyuck;* Kim, Ki Hyun.* Pharbilignan C induces apoptosis through a mitochondria-mediated intrinsic pathway in human breast cancer cells. Bioorg. Med. Chem. Lett. 2016, 26, 4645−4649.
154. Jegal, Jonghwan; Park, Sang-A; Chung, Ki Wung; Chung, Hae Young; Lee, Jaewon; Jeong, Eun Ju; Kim, Ki Hyun; Yang, Min Hye. Tyrosinase inhibitory flavonoid from Juniperus communis fruits. Biosci. Biotechnol. Biochem. 2016, 80, 2311−2317.
153. Lee, Seoung Rak; Park, Jun Yeon, Yu, Jae Sik, Lee, Sung Ok; Ryu, Ja-Young; Choi, Sang-Zin; Kang, Ki Sung; Yamabe, Noriko;* Kim, Ki Hyun.* Odisolane, a Novel Oxolane Derivative and Antiangiogenic Constituents from the Fruits of Mulberry (Morus alba L.). J. Agric. Food Chem. 2016, 64, 3804−3809.
152. Lee, Seulah; Moon, Eunjung; Choi, Sang Un; Kim, Ki Hyun.* Lignans from the Twigs of Euonymus alatus (Thunb.) Sieb. and their Biological Evaluation. Chem. Biodivers. 2016, 13, 1391−1396.
151. Lee, Dahae; Choi, Young Ok; Kim, Ki Hyun; Chin, Young-Won; Namgung, Hojin; Yamabe, Noriko, Jung, Kiwon. Protective effect of α-mangostin against iodixanol-induced apoptotic damage in LLC-PK1 cells. Bioorg. Med. Chem. Lett. 2016, 26, 3806-3809.
150. Lee, Seulah; Tamayo-Castillo, Giselle; Pang, Changhyun; Clardy, Jon; Cao, Shugeng; Kim, Ki Hyun.* Diketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465A. Bioorg. Med. Chem. Lett. 2016, 26, 2438−2441.
149. Eom, Hee Jeong; Kang, Hee Rae; Kim, Ho Kyong; Jung, Eun Bee; Park, Hyun Bong; Kang, Ki Sung; Kim, Ki Hyun.* Bioactivity-guided isolation of antioxidant triterpenoids from Betula platyphylla var. japonica bark. Bioorg. Chem. 2016, 66, 97-101.
148. Eom, Hee Jeong; Park, Yong Joo; Kang, Hee Rae; Kim, Ha Ryong; Bang, In Jae; Park, Hyun Bong; Chung, Kyu Hyuck; Kim, Ki Hyun.* Inhibitory effect of Sphagnum palustre extract and its bioactive compounds on aromatase activity. Bangladesh J. Pharmacol. 2016, 11, 661-665.
147. An, Ji-Hun; Jin, Feng; Kim, Hak Sung; Ryu, Hyung Chul; Kim, Jae Sun; Kim, Hyuk Min; Kim, Ki Hyun; Kiyonga, Alice Nguvoko; Jung, Kiwon. Investigation of the Polymorphic Transformation of the Active Pharmaceutical Ingredient Clopidogrel Bisulphate Using the Ionic Liquid AEImBF4. Cryst. Growth Des. 2016, 16, 1829−1836.
146. An, Ji-Hun; Jin, Feng; Kim, Hak Sung; Ryu, Hyung Chul; Kim, Jae Sun; Kim, Hyuk Min; Kiyonga, Alice Nguvoko; Min, Dong Sun; Youn, Wonno; Kim, Ki Hyun;* Jung, Kiwon.* Application of ionic liquid to polymorphic transformation of anti-viral/HIV drug adefovir dipivoxil. Arch. Pharm. Res. 2016, 39, 646-659.
145. Lee, Seoung Rak; Beemelmanns, Christine; Tsuma, Leah M. M.; Clardy, Jon; Cao, Shugeng;* Kim, Ki Hyun.* A new diketopiperazine, cyclo(D-trans-Hyp-L-Leu) from a Kenyan bacterium Bacillus licheniformis LB 8CT. Nat. Prod. Commun. 2016, 11, 461-463.
144. Yu, Jae Sik; Moon, Eunjung; Choi, Sang Un; Kim, Ki Hyun.* Asarotonide, a new phenylpropanoid with a rare natural acetonide group from the rhizomes of Acorus gramineus. Tetrahedron Lett. 2016, 57, 1699-1701.
143. Kim, Chung Sub; Subedi, Lalita; Kim, Sun Yeou; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Diterpenes from the Trunk of Abies holophylla and Their Potential Neuroprotective and Anti-inflammatory Activities. J. Nat. Prod. 2016, 79, 387–394.
142. Lee, Dahae; Ko, Hyeonseok; Kim, Young-Joo; Kim, Su-Nam; Choi, Kyung-Chul; Yamabe, Noriko; Kim, Ki Hyun; Kang, Ki Sung; Kim, Hyun Young; Shibamoto, Takayuki. Inhibition of A2780 Human Ovarian Carcinoma Cell Proliferation by a Rubus Component, Sanguiin H-6. J. Agric. Food Chem. 2016, 64, 801-805.
141. Jung, Yujung; Cao, Yongkai; Paudel, Suresh; Kim, Ki Hyun; Yoon, Goo; Cheon, Seung Hoon; Lee, Jee-Young; Kim, Su-Nam; Kim, Yong Kee. A Novel Partial PPARα/γ Dual Agonist SN159 Improves Insulin Sensitivity. Bull. Korean Chem. Soc. 2016, 37, 226–233.
140. Lee, Seoung Rak; Clardy, Jon; Senger, Donald R.; Cao, Shugeng; Kim, Ki Hyun.* Iridoid and phenylethanoid glycosides from the aerial part of Barleria lupulina. Braz. J. Pharmacog. 2016, 26, 281-284.
139. Suh, Won Se; Lee, Seoung Rak; Kim, Chung Sub; Moon, Eunjung; Kim, Sun Yeou; Choi, Sang Un; Kang, Ki Sung; Lee, Kang Ro; Kim, Ki Hyun.* A new monoacylglycerol from the fruiting bodies of Gymnopilus spectabilis. J. Chem. Res. 2016, 40, 156-159.
138. Choi, Chang-Ik, Eom, Hee Jeong; Kim, Ki Hyun.* Antioxidant and α-Glucosidase Inhibitory Phenolic Constituents of Lactuca indica L. Russ. J. Bioorg. Chem. 2016, 42, 310-315.
137. Jung, Kiwon; Lee, Dahae; Yu, Jae Sik; Namgung, Hojin; Kang, Ki Sung; Kim, Ki Hyun.* Protective effect and mechanism of action of saponins isolated from the seeds of gac (Momordica cochinchinensis Spreng.) against cisplatin-induced damage in LLC-PK1 kidney cells. Bioorg. Med. Chem. Lett. 2016, 26, 1466–1470.
136. Park, J. Y.; Shin, M. S.; Kim, S. N.; Kim, H. Y.; Kim, K. H.; Shin, K. S.; Kang, K. S. Polysaccharides from Korean Citrus hallabong peels inhibit angiogenesis and breast cancer cell migration. Int. J. Biol. Macromol. 2016, 85, 522-529.
135. Lee, Seoung Rak; Han, Ju-Yeon; Kang, Hee Rae; Lee, Hye Lim; Noh, Hyung-Jun; Cha, Jae‑Soon; Kang, Ki Sung; Lee, Chan-Jung; Kim, Ki Hyun.* A New Steroidal Saponin from the Tubers of Ophiopogon japonicus and Its Protective Effect Against Cisplatin-Induced Renal Cell Toxicity J. Braz. Chem. Soc. 2016, 27, 706-711.
134. Park, Jun Yeon; You, Hwan; Lee, Dahae; Huh, Wonsang; Hwang, Gwi Seo; No, Kyoung Tai; Kim, Ki Hyun; Ham, Jungyeob; Yamabe, Noriko; Kim, Younghoon; Kang, Ki Sung. Comparison of the wound-healing effects of ginsenosides, their metabolites, and aglycones. Bull. Korean Chem. Soc. 2016, 37, 52-55.
133. Kang, Hee Rae; Lee, Dahae; Eom, Hee Jeong; Lee, Seoung Rak; Lee, Kang Ro; Kang, Ki Sung;* Kim, Ki Hyun.* Identification and mechanism of action of renoprotective constituents from peat moss Sphagnum palustre in cisplatin-induced nephrotoxicity. J. Funct. Foods 2016, 20, 358–368.
132. Lee, Seoung Rak; Jung, Kiwon; Noh, Hyung Jun; Park, Yong Joo; Lee, Hye Lim; Lee, Kang Ro; Kang, Ki Sung; Kim, Ki Hyun.* A new cerebroside from the fruiting bodies of Hericium erinaceus and its applicability to cancer treatment. Bioorg. Med. Chem. Lett. 2015, 25, 5712–5715.
131. Woo, Kyeong Wan; Suh, Won Se; Subedi, Lalita; Kim, Sun Yeou; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Phenolic Derivatives from the Stems of Lagerstroemia indica and Their Biological Activity. Heterocycles 2015, 91, 2355-2366.
130. Park, Cheon-Soo; Ahn, Yong Chel; Lee, Dahae; Moon, Sung Won; Kim, Ki Hyun; Yamabe, Noriko Yamabe; Hwang, Gwi Seo; Jang, Hyuk Jai; Lee, Heesu; Kang, Ki Sung; Lee, Jae Wook. Synthesis of apoptotic chalcone analogues in HepG2 human hepatocellular carcinoma cells. Bioorg. Med. Chem. Lett. 2015, 25, 5705–5707.
129. Lee, Seulah; Jung, Kiwon; Lee, Dahae; Lee, Seoung Rak; Lee, Kang Ro; Kang, Ki Sung; Kim, Ki Hyun.* Protective effect and mechanism of action of lupane triterpenes from Cornus walteri in cisplatin-induced nephrotoxicity. Bioorg. Med. Chem. Lett. 2015, 25, 5613–5618.
128. Kim, Chung Sub; Subedi, Lalita; Kim, Sun Yeou; Choi, Sang Un; Choi, Sang Zin; Son, Mi Won; Kim, Ki Hyun; Lee, Kang Ro. Two new phenolic compounds from the white flower of Impatiens balsamina. Phytochem. Lett. 2015, 14, 215–220.
127. Kim, Chung Sub; Subedi, Lalita; Park, Kyoung Jin; Kim, Sun Yeou; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Salicin derivatives from Salix glandulosa and their biological activities. Fitoterapia 2015, 106, 147-152.
126. Kim, Ki Hyun; Moon, Eunjung; Lee, Seoung Rak; Park, Kyoung Jin; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro. Chemical Constituents of the Seeds of Raphanus sativus and their Biological Activity. J. Braz. Chem. Soc. 2015, 26, 2307-2312.
125. Choi, Chang-Ik; Lee, Seoung Rak; Kim, Ki Hyun.* Antioxidant and α-glucosidase inhibitory activities of constituents from Euonymus alatus twigs. Ind. Crop. Prod. 2015, 76, 1055–1060.
124. Suh, Won Se; Kim, Ki Hyun; Kim, Ho Kyung; Choi, Sang Un; Lee, Kang Ro. Three New Lignan Derivatives from Lindera glauca (Siebold et Zucc.) Blume. Helv. Chim. Acta 2015, 98, 1087-1094.
123. Park, Jun Yeon; Lee, Dahae; Jang, Hyuk-Jai; Jang, Dae Sik; Kwon, Hak Cheol; Kim, Ki Hyun; Kim, Su-Nam; Hwang, Gwi Seo; Kang, Ki Sung; Eom, Dae-Woon. Protective Effect of Artemisia asiatica Extract and Its Active Compound Eupatilin against Cisplatin-Induced Renal Damage. Evid-Based Complement. Alternat. Med. 2015, 2015, ID483980.
122. Byun, Sanguine; Lim, Semi; Mun, Ji Young; Kim, Ki Hyun; Ramadhar, Timothy R.; Farrand, Lee; Shin, Seung Ho; Thimmegowda, N. R.; Lee, Hyong Joo; Frank, David A.; Clardy, Jon; Lee, Sam W.; Lee, Ki Won. Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways. J. Biol. Chem. 2015, 290, 23553-23562.
121. Kim, Ki Hyun; Kang, Hee Rae; Moon, Eunjung; Choi, Sang Un; Kang, Ki Sung; Kim, Sun Yeou; Lee, Kang Ro. A New N-Glucosylated Indole Alkaloid and a New O-Serine Glycoside from Berberis koreana. Heterocycles 2015, 91, 1429-1438.
120. Kim, Ki Hyun; Moon, Eunjung; Cha, Joon Min; Lee, Seulah; Yu, Jae Sik; Kim, Chung Sub; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro. Anti-Neuroinflammatory and Anti-Proliferative Activities of Constituents from Tilia amurensis Rupr. Chem. Pharm. Bull. 2015, 63, 837–842.
119. Kang, Hee Rae; Eom, Hee Jeong; Lee, Seoung Rak; Choi, Sang Un; Kang, Ki Sung; Lee, Kang Ro; Kim, Ki Hyun.* Bioassay-guided Isolation of Antiproliferative Triterpenoids from Euonymus alatus Twigs. Nat. Prod. Commun. 2015, 10, 1929–1932.
118. Jang, Sung Wan; Suh, Won Se; Kim, Chung Sub; Kim, Ki Hyun; Lee, Kang Ro. A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs. Arch. Pharm. Res. 2015, 38, 1943–1951.
117. Han, Sang Hyun; Suh, Won Se; Park, Kyoung Jin; Kim, Ki Hyun; Lee, Kang Ro. Two new phenylpropane glycosides from Allium tuberosum Rottler. Arch. Pharm. Res. 2015, 38, 1312-1316.
116. Roh, Hyun Jung; Noh, Hye-Ji; Na, Chun Su; Kim, Chung Sub; Kim, Ki Hyun; Hong, Cheol Yi; Lee, Kang Ro. Phenolic compounds from the leaves of Stewartia pseudocamellia Maxim. and their whitening activities. Biomol. Ther. 2015, 23, 283-289.
115. Lee, Seung Young; Suh, Won Se; Kim, Ho Kyung; Lee, Il Kyun; Choi, Sang Un; Kim, Ki Hyun Lee, Kang Ro. Triterpene saponins from the aerial parts of Ilex Cornuta and their cytotoxic activity. Heterocycles 2015, 91, 1187-1197
114. Kim, Chung Sub; Subedi, Lalita; Kim, Sun Yeou; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Lignan glycosides from the twigs of Chaenomeles sinensis and their biological activities. J. Nat. Prod. 2015, 78, 1174–1178.
113. Woo, Kyeong Wan; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Ursane saponins from the stems of Firmiana simplex and their cytotoxic activity. J. Braz. Chem. Soc. 2015, 26, 1450-1456.
112. Park, Hye-Jin; Yang, Hye Jeong; Kim, Ki Hyun; Kim, Sang Hee. Aqueous extract of Orostachys japonicus A. Berger exerts immunostimulatory activity in RAW 264.7 macrophages. J. Ethnopharmacol. 2015, 170, 210-217.
111. Kim, Ki Hyun; Clardy, Jon; Senger, Donald; Cao, Shugeng. Chakyunglupulins A and B, two novel 4,8,8-trimethylcyclooct-2-enone derivatives from Barleria lupulina. Tetrahedron Lett. 2015, 56, 2732–2734.
110. Kim, Ki Hyun; Beemelmanns, Christine; Clardy, Jon; Cao, Shugeng. A new antibacterial octaketide and cytotoxic phenylethanoid glycosides from Pogostemon cablin (Blanco) Benth. Bioorg. Med. Chem. Lett. 2015, 25, 2834–2836.
109. Kim, Ki Hyun; Kang, Hee Rae; Eom, Hee Jeong; Kim, Chung Sub; Choi, Sang Un; Lee, Kang Ro. A new aliphatic alcohol and cytotoxic chemical constituents from Acorus gramineus rhizomes. Biosci. Biotechnol. Biochem. 2015, 79, 1402-1405.
108. Lee, Dahae;a Kim, Ki Hyun;a Moon, Sung Won; Lee, Heesu; Kang, Ki Sung; Lee, Jae Wook. Synthesis and biological evaluation of chalcone analogues as protective agents against cisplatin-induced cytotoxicity in kidney cells. Bioorg. Med. Chem. Lett. 2015, 25, 1929-1932. (aThese authors contributed equally to this work)
107. Noh, Hyung Jun; Yang, Hyo Hyun; Kim, Geum Soog; Lee, Seung Eun; Lee, Dae Young; Choi, Je Hun; Kim, Seung Yu; Lee, Eun Suk; Ji, Seung Heon; Kang, Ki Sung; Park, Hye-Jin; Kim, Jae-Ryong,* Kim, Ki Hyun.* Chemical constituents of Hericium erinaceum associated with the inhibitory activity against cellular senescence in human umbilical vascular endothelial cells. J. Enzyme Inhib. Med. Chem. 2015, 30, 934–940.
106. Kim, Ki Hyun; Park, Yong Joo; Chung, Kyu Hyuck; Yip, M. L. Richard; Clardy, Jon; Senger, Donald; Cao, Shugeng. Iridoid Glycosides from Barleria lupulina. J. Nat. Prod. 2015, 78, 320–324.
105. Noh, Hyung Jun; Hwang, Dukhyun; Lee, Eun Suk; Hyun, Jae Wook; Yi, Pyoung Ho; Kim, Geum Soog; Lee, Seung Eun; Pang, Changhyun; Park, Yong Joo; Chung, Kyu Hyuck; Kim, Gun Do,* Kim, Ki Hyun.* Anti-inflammatory activity of a new cyclic peptide, citrusin XI, isolated from the fruits of Citrus unshiu. J. Ethnopharmacol. 2015, 163, 106–112.
104. Eom, Dae-Woon; Lee, Ji Hwan; Kim, Young-Joo; Hwang, Gwi Seo; Kim, Su-Nam; Kwak, Jin Ho; Cheon, Gab Jin; Kim, Ki Hyun; Jang, Hyuk-Jai; Ham, Jungyeob; Kang, Ki Sung; Yamabe, Noriko. Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer action in PC3 prostate cancer cells. BMB Rep. 2015, 48, 461-466.
103. Kim, Chung Sub; Moon, Eunjung; Choi, Sang Un; Kim, Sun Yeou; Lee, Kang Ro; Kim, Ki Hyun.* Cytotoxic and anti-inflammatory disulfide compounds from the fruiting bodies of Boletus pseudocalopus. J. Antibiot. 2015, 68, 414–416
102. Baik, Sangyul; Kim, Namhun; Kim, Tae-il; Chae, Heeyeop; Kim, Ki Hyun; Pang, Changhyun; Suh, Kahp-Yang. Theoretical analysis of flexible strain-gauge sensor with nanofibrillar mechanical interlocking. Current Applied Physics 2015, 15, 274–278
101. Kim, Ki Hyun; Bae, Gyu-Un; Kim, Yong Kee. Plantago asiatica extracts inhibit UV-induced matrix metalloproteinase-1 in human dermal fibroblasts and prevent skin photoaging in hairless mice. Bull. Korean Chem. Soc. 2015, 36, 659-664.
100. Kim, Ki Hyun; Moon, Eunjung; Choi, Sang Un; Pang, Changhyun; Kim, Sun Yeou; Lee, Kang Ro. Identification of cytotoxic and anti-inflammatory constituents from the bark of Toxicodendron vernicifluum (Stokes) F.A. Barkley. J. Ethnopharmacol. 2015, 162, 231-237.
99. Kim, Ki Hyun; Kim, Chung Sub; Park, Yong Joo; Moon, Eunjung; Choi, Sang Un; Lee, Jei Hyun; Kim, Sun Yeou; Lee, Kang Ro. Anti-inflammatory and antitumor phenylpropanoid sucrosides from the seeds of Raphanus sativus. Bioorg. Med. Chem. Lett. 2015, 25, 96-99.
98. Cheon, Gab Jin;a Kim, Ki Hyun; a Park, Jun Yeon; Lee, Dahae; Jang, Hyuk-Jai; Kwak, Jin Ho; Choi, Kun Moo; Kim, Ji Hoon; Hwang, Gwi Seo; Ham, Jungyeob; Lee, Sanghyun; Eom, Dae-Woon; Kang, Ki Sung. Caspase-Mediated Apoptotic Effects of Diol-Type Ginseng Sapogenins on Human Hepatoma Cell Lines. Bull. Korean Chem. Soc. 2015, 36, 431-434. (aThese authors contributed equally to this work)
97. Kim, Ki Hyun; Moon, Eunjung; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro. Tiliabisflavan A, a New Flavan-3-ol Dimer from Tilia amurensis with Cytotoxic and Anti-inflammatory Effects. Bull. Korean Chem. Soc. 2015, 36, 367-369.
96. Kim, Ki Hyun; Moon, Eunjung; Kang, Ki Sung; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro. Alkaloids from Acorus gramineus Rhizomes and their Biological Activity. J. Braz. Chem. Soc. 2015, 26, 3-8.
95. Kim, Ki Hyun;* Beemelmanns, Christine; Murillo, Catalina; Guillén, Anny; Umaña, Loengrin; Tamayo-Castillo, Giselle; Kim, Su‑Nam; Clardy, Jon; Cao, Shugeng. Naphthalenones and isocoumarins from a Costa Rican fungus Xylariaceae sp. CR1546C. J. Chem. Res. 2014, 38, 722-725.
94. Cho, Hyeon Kyung; Kim, Chung Sub; Suh, Won Se; Kim, Ki Hyun; Lee, Kang Ro. Two new triterpene saponins from the tubers of Stachys sieboldii. Heterocycles 2014, 89, 2619-2626.
93. Kwak, Jin Ho; Park, Jun Yeon; Lee, Dahae; Kwak, Jae Young; Park, Eun Hwa; Kim, Ki Hyun; Park, Hye-Jin; Kim, Hyun Young; Jang, Hyuk Jae; Ham, Jungyeob; Hwang, Gwi Seo; Yamabe, Noriko; Kang, Ki Sung. Inhibitory effects of ginseng sapogenins on the proliferation of triple negative breast cancer MDA-MB-231 cells. Bioorg. Med. Chem. Lett. 2014, 24, 5409-5412.
92. Kim, Chung Sub; Shin, Bora; Kwon, Oh Wook; Kim, Sun Yeou; Choi, Sang Un; Oh, Dong-Chan; Kim, Ki Hyun; Lee, Kang Ro. Holophyllin A, a rearranged abietane-type diterpenoid from the trunk of Abies holophylla. Tetrahedron Lett. 2014, 55, 6504–6507.
91. Kim, Chung Sub; Kwon, Oh Wook; Kim, Sun Yeou; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Five New Oxylipins from Chaenomeles sinensis. Lipids 2014, 49, 1151-1159.
90. Cho, Hyeon Kyung; Suh, Won Se; Kim, Ki Hyun; Kim, Sun Yeou; Lee, Kang Ro. Phytochemical constituents of Salsola komarovii and their effects on NGF induction. Nat. Prod. Sci. 2014, 20, 95-101.
89. Woo, Kyeong Wan; Park, Jong Eel; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Phytochemical constituents of Bletilla striata and their cytotoxic activity. Nat. Prod. Sci. 2014, 20, 91-94.
88. Kim, Chung Sub; Kim, Ki Hyun; Lee, Kang Ro. Phytochemical constituents of the leaves of Hosta longipes. Nat. Prod. Sci. 2014, 20, 86-90.
87. Woo, Kyeong Wan; Han, Ji Young; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro Lee. Triterpenes from Perilla frutescens var. acuta and their cytotoxic activity. Nat. Prod. Sci. 2014, 20, 71-75.
86. Kim, Chung Sub; Kwon, Oh Wook; Kim, Sun Yeou; Choi, Sang Un; Kim, Jae Yoon; Han, Ji Young; Choi, Soo Im; Choi, Jong Gil; Kim, Ki Hyun; Lee, Kang Ro. Phenolic Glycosides from the Twigs of Salix glandulosa. J. Nat. Prod. 2014, 77, 1955−1961.
85. Kim, Ki Hyun; Moon, Eunjung; Ha, Sang Keun; Suh, Won Se; Kim, Ho Kyung; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro. Bioactive Lignan Constituents from the Twigs of Lindera glauca. Chem. Pharm. Bull. 2014, 62, 1136−1140.
84. Noh, Hyung Jun; Yoon, Ju Young; Kim, Geum Sook; Lee, Seung Eun; Lee, Dae Young; Choi, Je Hun; Kim, Seung Yu; Kang, Ki Sung; Cho, Jae Youl; Kim, Ki Hyun.* Benzyl alcohol derivatives from the mushroom Hericium erinaceum attenuate LPS-stimulated inflammatory response through the regulation of NF-iB and AP-1 activity. Immunopharmacol. Immunotoxicol. 2014, 36, 349–354.
83. Kim, Ki Hyun; Ramadhar, Timothy R.; Beemelmanns, Christine; Cao, Shugeng; Poulsen, Michael; Currie, Cameron R.; Clardy, Jon. Natalamycin A, an ansamycin from a termite-associated Streptomyces sp. Chem. Sci. 2014, 5, 4333–4338.
82. Kim, Ki Hyun; Woo, Kyeong Wan; Moon, Eunjung; Choi, Sang Un; Kim, Sun Yeou; Choi, Sang Zin; Son, Mi Won; Lee, Kang Ro. Identification of antitumor lignans from the seeds of morning glory (Pharbitis nil). J. Agric. Food Chem. 2014, 62, 7746−7752.
81. Kim, Chung Sub; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro. Two new diterpenoids from Thuja orientalis and their cytotoxicity. Bull. Korean Chem. Soc. 2014, 35, 2855-2858.
80. Woo, Kyeong Wan; Kwon, Oh Wook; Kim, Sun Yeou; Choi, Sang Zin; Son, Mi Won; Kim, Ki Hyun; Lee, Kang Ro. Phenolic derivatives from the rhizomes of Dioscorea nipponica and their anti-neuroinflammatory and neuroprotective activities. J. Ethnopharmacol. 2014, 155, 1164-1170.
79. Kim, Ki Hyun; Kim, Ho Kyung; Kim, Su-Nam; Choi, Sang Un. A new cytotoxic cadinane sesquiterpene from Berberis koreana. Bull. Korean Chem. Soc. 2014, 35, 3346 - 3348.
78. Kim, Chung Sub; Kwon, Oh Wook; Kim, Sun Yeou; Kim, Ki Huyn; Lee, Kang Ro. A new cyclic triterpene saponin from Phyteuma japonicum. Heterocycles 2014, 89, 1913-1922.
77. Kim, Ki Hyun; Choi, Sang Un; Noh, Hyung Jun; Zee, Okpyo; Lee, Kang Ro. Cytotoxic ergosterol derivatives from the mushroom Naematoloma fasciculare. Nat. Prod. Sci. 2014, 20, 76-79.
76. Converse, Paul J.; Xing, Yalan; Kim, Ki Hyun; Tyagi, Sandeep; Li, Si-Yang; Almeida, Deepak V.; Nuermberger, Eric L.; Grosset, Jacques H.; Kishi, Yoshito. Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease. PLoS Negl. Trop. Dis. 2014, 8, e2618.
75. Kim, Ki Hyun; Moon, Eunjung; Kim, Sun Yeou; Choi, Sang Un; Lee, Jei Hyun; Lee, Kang Ro. 4-Methylthio-butanyl derivatives from the seeds of Raphanus sativus and their biological evaluation on anti-inflammatory and antitumor activities. J. Ethnopharmacol. 2014, 151, 503-508.
74. Kim, Ki Hyun; Moon, Eunjung; Kim, Sun Yeou; Choi, Sang Un; Son, Mi Won; Choi, Sang Zin; Lee, Kang Ro. Bioactive sesquiterpenes from the essential oil of Thuja orientalis. Planta Med. 2013, 79, 1680-1684.
73. Kim, Ki Hyun; Moon, Sae Rom; Kim, Chung Sub; Woo, Kyeong Wan; Choi, Sang Un; Lee, Kang Ro. Lignan glucosides from Sinomenium acutum rhizome. Biosci. Biotechnol. Biochem. 2013, 77, 2144-2147.
72. Kim, Ki Hyun; Choi, Sang Un; Son, Mi Won; Choi, Sang Zin; Clardy, Jon; Lee, Kang Ro. Pharbinilic acid, an allogibberic acid from morning glory (Pharbitis nil). J. Nat. Prod. 2013, 76, 1376–1379.
71. Kim, Ki Hyun; Moon, Eunjung; Choi, Sang Un; Kim, Sun Yeou; Lee, Kang Ro. Polyphenols from the bark of Rhus verniciflua and their biological evaluation on antitumor and anti-inflammatory activities. Phytochemistry 2013, 92, 113-121.
70. Kim, Ki Hyun; Moon, Eunjung; Choi, Sang Un; Kim, Sun Yeou; Lee, Kang Ro. Lanostane triterpenoids from the mushroom Naematoloma fasciculare. J. Nat. Prod. 2013, 76, 845-851.
69. Song, No Joon; Yoon, Hyang Jin; Kim, Ki Hyun; Jung, So Ra; Jang, Woo Seok; Seo, Cho Rong; Lee, Young Min; Kweon, Dae Hyuk; Hong, Joung Woo; Lee, Jeong Soo; Park, Ki Moon; Lee, Kang Ro; Park, Kye Won. Butein is a novel anti-adipogenic compound. J. Lipid Res. 2013, 54, 1385-1396.
68. Kim, Ki Hyun; Ha, Sang Keun; Choi, Sang Un; Kim, Sun Yeou; Lee, Kang Ro. Phenolic constituents from the twigs of Euonymus alatus and their cytotoxic and anti-inflammatory activity. Planta Med. 2013, 79, 361-364.
67. Kim, Ki Hyun; Moon, Eunjung; Kim, Ho Kyung; Oh, Ju Yeoun; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro. Phenolic constituents from the rhizomes of Acorus gramineus and their biological evaluation on antitumor and anti-inflammatory activities. Bioorg. Med. Chem. Lett. 2012, 22, 6155-6159.
66. Kim, Ki Hyun; Moon, Eunjung; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro. Lignan constituents of Tilia amurensis and their biological evaluation on antitumor and anti-inflammatory activities. Food Chem. Toxicol. 2012, 50, 3680-3686.
65. Kim, Ki Hyun; Noh, Hyung Jun; Choi, Sang Un; Lee, Kang Ro. Isohericenone, a new cytotoxic isoindolinone alkaloid from Hericium erinaceum. J. Antibiot. 2012, 65, 575-577.
64. Lee, Seung Young; Kim, Ki Hyun; Lee, Il Kyun; Lee, Kyu Ha; Choi, Sang Un; Lee, Kang Ro. A new flavonol glycoside from Hylomecon vernalis. Arch. Pharm. Res. 2012, 35, 415-421.
63. Ji, Hye Young; Lee, Hyeri; Kim, Jeong-Han; Kim, Ki Hyun; Lee, Kang Ro; Shim, Hyun Joo; Son, Miwon; Lee, Hye Suk. In vitro metabolism of corydaline in human liver microsomes and hepatocytes using liquid chromatography-ion trap mass spectrometry. J. Sep. Sci. 2012, 35, 1102-1109.
62. Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Three New Fatty Acid Esters from the Mushroom Boletus pseudocalopus. Lipids 2012, 47, 593-599.
61. Kim, Ki Hyun; Choi, Sang Un; Kim, Chung Sub; Lee, Kang Ro. Cytotoxic steroids from the trunk of Berberis koreana. Biosci. Biotechnol. Biochem. 2012, 76, 825-827.
60. Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Gymnopilin K, a new cytotoxic gymnopilin from Gymnopilus spectabilis. J. Antibiot. 2012, 65, 135-137.
59. Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Turtschamide, a cytotoxic putrescine bisamide from Corydalis turtschaninovii. Tetrahedron Lett. 2012, 53, 1490-1492.
58. Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Cytotoxic Triterpenoids from Berberis koreana. Planta Med. 2012, 78, 86-89.
57. Kim, Ki Hyun; Kim, Ho Kyung; Choi, Sang Un; Moon, Eunjung; Kim, Sun Yeou; Lee, Kang Ro. Bioactive Lignans from the Rhizomes of Acorus gramineus. J. Nat. Prod. 2011, 74, 2187-2192.
56. Park, Cheol Hyeong; Kim, Ki Hyun; Lee, Il Kyun; Lee, Seung Young; Choi, Sang Un; Lee, Jei Hyun; Lee, Kang Ro. Phenolic Constituents of Acorus gramineus. Arch. Pharm. Res. 2011, 34, 1289-1296.
55. Kim, Ki Hyun; Ha, Sang Keun; Choi, Sang Un; Kim, Sun Yeou; Lee, Kang Ro. Bioactive Phenolic Constituents from the seeds of Pharbitis nil. Chem. Pharm. Bull. 2011, 59, 1425-1429.
54. Lee, Tae Ho, Kim, Ki Hyun, Lee, Sung Ok, Lee, Kang Ro, Son, Miwon, Jin, Mirim. Tetrahydroberberine, an Isoquinoline Alkaloid Isolated from Corydalis Tuber, Enhances Gastrointestinal Motor Function. J. Pharmacol. Exp. Ther. 2011, 338, 917-924.
53. Kim, Ki Hyun; Lee, Kyu Ha; Shin, Young June; Choi, Sang Un; Lee, Kang Ro. New Cytotoxic d-Valerolactones from Cornus walteri. Bull. Korean Chem. Soc. 2011, 32, 2443-2445.
52. Kim, Ki Hyun; Choi, Sang Un; Choi, Sang Zin; Son, Mi Won; Lee, Kang Ro. Withanolides from the Rhizomes of Dioscorea japonica and Their Cytotoxicity. J. Agric. Food Chem. 2011, 59, 6980-6984.
51. Kim, Ki Hyun; Lee, Il Kyun; Choi, Sang Un; Lee, Jei Hyun; Moon, Eunjung; Kim, Sun Yeou; Lee, Kang Ro. New triterpenoids from the tubers of Corydalis ternata: Structural elucidation and bioactivity evaluation. Planta Med. 2011, 77, 1555-1558.
50. Lee, IL Kyun, Kim, Ki Hyun, Lee, Seung Young, Choi, Sang Un, Lee, Kang Ro. Three New Megastigmane Glucopyranosides from the Cardamine komarovii. Chem. Pharm. Bull. 2011, 59, 773-777.
49. Kim, Ki Hyun; Choi, Jung Wook; Choi, Sang Un; Lee, Kang Ro. Cytotoxic sesquiterpenoid from the seeds of Amomum xanthioides. Nat. Prod. Sci. 2011, 17, 10-13.
48. Kim, Ki Hyun; Moon, Eunjung; Choi, Sang Un; Kim, Sun Yeou; Lee, Kang Ro. Biological evaluation of phenolic constituents from the trunk of Berberis koreana. Bioorg. Med. Chem. Lett. 2011, 21, 2270-2273.
47. Kim, Ki Hyun; Kim, Min Ah; Moon, Eunjung; Kim, Sun Yeou; Choi, Sang Zin; Son, Mi Won; Lee, Kang Ro. Furostanol saponins from the rhizomes of Dioscorea japonica and their effects on NGF induction. Bioorg. Med. Chem. Lett. 2011, 21, 2075-2078.
46. Kim, Ki Hyun; Lee, Kyu Ha; Kim, Ho Kyung; Moon, Eunjung; Kim, Sung-Hoon; Kim, Sun Yeou; Kim, Kyung Ran; Lee, Kang Ro. Anti-neuroinflammatory constituents from the root extract of Paris verticillata. Can. J. Chem. 2011, 89, 441-445.
45. Kim, Ki Hyun; Choi, Jung Wook; Choi, Sang Un; Ha, Sang Keun; Kim, Sun Yeou; Park, Hee-Juhn; Lee, Kang Ro. The chemical constituents of Piper kadsura and their cytotoxic and anti-neuroinflammatory activities. J. Enzyme Inhib. Med. Chem. 2011, 26, 254-260.
44. Kim, Ki Hyun; Choi, Sang Un; Kim, Young Choong; Lee, Kang Ro. Tirucallane triterpenoids from Cornus walteri. J. Nat. Prod. 2011, 74, 54-59.
43. Jeong, Gil-Saeng; Li, Bin; Lee, Dong-Sung; Kim, Ki Hyun; Lee, Il Kyun; Lee, Kang Ro; Kim, Youn-Chul. Cytoprotective and anti-inflammatory effects of spinasterol via the induction of heme oxygenase-1 in murine hippocampal and microglial cell lines. Int. Immunopharmacol. 2010, 10, 1587-1594.
42. Kim, Ki Hyun; Choi, Sang Un; Son, Mi Won; Lee, Kang Ro. Two new phenolic amides from the seeds of Pharbitis nil. Chem. Pharm. Bull. 2010, 58, 1532-1535.
41. Kim, Ki Hyun; Noh, Hyung Jun; Choi, Sang Un; Park, Ki Moon; Seok, Soon-Ja; Lee, Kang Ro. Lactarane sesquiterpenoids from Lactarius subvellereus and their cytotoxicity. Bioorg. Med. Chem. Lett. 2010, 20, 5385-5388.
40. Kim, Ki Hyun; Noh, Hyung Jun; Choi, Sang Un; Park, Ki Moon; Seok, Soon-Ja; Lee, Kang Ro. Russulfoen, a new cytotoxic marasmane sesquiterpene from Russula foetens. J. Antibiot. 2010, 63, 575-577.
39. Kim, Ki Hyun; Piao, Cheng Jie; Choi, Sang Un; Son, Mi Won; Lee, Kang Ro. New cytotoxic tetrahydroprotoberberine-aporphine dimeric and aporphine alkaloids from Corydalis turtschaninovii. Planta Med. 2010, 76, 1732-1738.
38. Kim, Ki Hyun; Ha, Sang Keun; Kim, Sun Yeou; Youn, Hyun Joo; Lee, Kang Ro. Constituents of Limonia acidissima inhibit LPS-induced nitric oxide production in BV-2 microglia. J. Enzyme Inhib. Med. Chem. 2010, 25, 887-892.
37. Kim, Ki Hyun; Choi, Jung Wook; Ha, Sang Keun; Kim, Sun Yeou; Lee, Kang Ro. Neolignans from Piper kadsura and their anti-neuroinflammatory activity. [Erratum to document cited in CA152:234364]. Bioorg. Med. Chem. Lett. 2010, 20, 3186-3187.
36. Kim, Ki Hyun; Moon, Eunjung; Kim, Sun Yeou; Lee, Kang Ro. Anti-melanogenic fatty acid derivatives from the tuber-barks of Colocasia antiquorum var. esculenta. Bull. Korean Chem. Soc. 2010, 31, 2051-2053.
35. Kim, Ki Hyun; Lee, Il Kyun; Piao, Cheng Jie; Choi, Sang Un; Lee, Jei Hyun; Kim, Yeong Shik; Lee, Kang Ro. Benzylisoquinoline alkaloids from the tubers of Corydalis ternata and their cytotoxicity. Bioorg. Med. Chem. Lett. 2010, 20, 4487-4490.
34. Kim, Ki Hyun; Lee, Kyu Ha; Choi, Sang Un; Kim, Kyung Ran; Lee, Kang Ro. Pyrrolizidine alkaloids from the roots of Paris verticillata. Heterocycles 2010, 81, 1493-1502.
33. Kim, Ki Hyun; Choi, Jung Wook; Choi, Sang Un; Seo, Eun-Kyoung; Lee, Kang Ro. Amoxantin A: a new bisnorlabdane diterpenoid from Amomum xanthioides. Bull. Korean Chem. Soc. 2010, 31, 1035-1037.
32. Kim, Ki Hyun; Chang, Sang Wook; Lee, Kang Ro. Feruloyl sucrose derivatives from Bistorta manshuriensis. Can. J. Chem. 2010, 88, 519-523.
31. Kim, Ki Hyun; Choi, Jung Wook; Choi, Sang Un; Lee, Kang Ro. Terpene glycosides and cytotoxic constituents from the seeds of Amomum xanthioides. Planta Med. 2010, 76, 461-464.
30. Lee, Il Kyun; Kim, Ki Hyun; Ryu, Shi Yong; Choi, Sang Un; Lee, Kang Ro. Phytochemical constituents from the flowers of Gymnaster koraiensis and their cytotoxic activities in vitro. Bull. Korean Chem. Soc. 2010, 31, 227-229.
29. Kim, Ki Hyun; Moon, Eunjung; Kim, Sun Yeou; Lee, Kang Ro. Lignans from the tuber-barks of Colocasia antiquorum var. esculenta and their antimelanogenic activity. J. Agric. Food Chem. 2010, 58, 4779-4785.
28. Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Bioactivity-guided isolation of cytotoxic triterpenoids from the trunk of Berberis koreana. Bioorg. Med. Chem. Lett. 2010, 20, 1944-1947.
27. Kim, Ki Hyun; Choi, Jung Wook; Ha, Sang Keun; Kim, Sun Yeou; Lee, Kang Ro. Neolignans from Piper kadsura and their anti-neuroinflammatory activity. Bioorg. Med. Chem. Lett. 2010, 20, 409-412.
26. Kim, Ki Hyun; Kim, Young Ho; Lee, Kang Ro. Isolation of hepatoprotective phenylpropanoid from Lactuca indica. Nat. Prod. Sci. 2010, 16, 6-9.
25. Lee, Il Kyun; Kim, Ki Hyun; Ryu, Shi Yong; Lee, Kang Ro. Two new sesquiterpene glucosides from Gymnaster koraiensis. Heterocycles 2009, 78, 2827-2835.
24. Nugroho, Agung; Kim, Ki Hyun; Lee, Kang Ro; Alam, Md. Badrul; Choi, Jae Sue; Kim, Won-Bae; Park, Hee-Juhn. Qualitative and quantitative determination of the caffeoylquinic acids on the Korean mountainous vegetables used for Chwinamul and their peroxynitrite-scavenging effect. Arch. Pharm. Res. 2009, 32, 1361-1367.
23. Kim, Ki Hyun; Choi, Sang Un; Ha, Sang Keun; Kim, Sun Yeou; Lee, Kang Ro. Biphenyls from Berberis koreana. J. Nat. Prod. 2009, 72, 2061-2064.
22. Kim, Ki Hyun; Ha, Sang Keun; Kim, Sun Yeou; Kim, Sung Hoon; Lee, Kang Ro. Limodissimin A: a new dimeric coumarin from Limonia acidissima. Bull. Korean Chem. Soc. 2009, 30, 2135-2137.
21. Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Neomastoidin A, a novel monoacylglycerol with an amino acid moiety from Macrolepiota neomastoidea. Chem. Lett. 2009, 38, 894-895.
20. Kim, Ki Hyun; Lee, Il Kyun; Kim, Kyung Ran; Ha, Sang Keun; Kim, Sun Yeou; Lee, Kang Ro. New benzamide derivatives and NO production inhibitory compounds from Limonia acidissima. Planta Med. 2009, 75, 1146-1151.
19. Kim, Ki Hyun; Park, Ki Moon; Choi, Sang Un; Lee, Kang Ro. Macrolepiotin, a new indole alkaloid from Macrolepiota neomastoidea. J. Antibiot. 2009, 62, 335-338.
18. Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Diterpene Glycosides from the Seeds of Pharbitis nil. J. Nat. Prod. 2009, 72, 1121-1127.
17. Chang, Sang Wook; Kim, Ki Hyun; Lee, Il Kyun; Choi, Sang Un; Ryu, Shi Yong; Lee, Kang Ro. Phytochemical constituents of Bistorta manshuriensis. Nat. Prod. Sci. 2009, 15, 234-240.
16. Lee, Il Kyun; Kim, Ki Hyun; Choi, Sang Un; Lee, Jae Hyun; Lee, Kang Ro. Phytochemical constituents of Thesium chinense TURCZ and their cytotoxic activities in vitro. Nat. Prod. Sci. 2009, 15, 246-249.
15. Chang, Sang Wook; Kim, Ki Hyun; Lee, Il Kyun; Choi, Sang Un; Lee, Kang Ro. Phytochemical constituents of Geranium eriostemon. Nat. Prod.Sci. 2009, 15, 151-155.
14. Kim, Ki Hyun; Chang, Sang Wook; Ryu, Shi Yong; Choi, Sang Un; Lee, Kang Ro. Phytochemical constituents of Nelumbo nucifera. Nat. Prod. Sci. 2009, 15, 90-95.
13. Choi, Jung Wook; Kim, Ki Hyun; Lee, Il Kyun; Choi, Sang Un; Lee, Kang Ro. Phytochemical constituents of Amomum xanthioides. Nat. Prod. Sci. 2009, 15, 44-49.
12. Park, Hyun Bong; Lee, Kyu Ha; Kim, Ki Hyun; Lee, Il Kyun; Noh, Hyung Jun; Choi, Sang Un; Lee, Kang Ro. Lignans from the roots of Berberis amurensis. Nat. Prod. Sci. 2009, 15, 17-21.
11. Kim, Ki Hyun; Lee, Il Kyun; Park, Ki Moon; Kim, Wan Kyu; Lee, Kang Ro. Isolation of γ-lactam alkaloids from the Macrolepiota neomastoidea. Bull. Korean Chem. Soc. 2008, 29, 1591-1593.
10. Kim, Ki Hyun; Lee, Kyu Ha; Choi, Sang Un; Kim, Young Ho; Lee, Kang Ro. Terpene and phenolic constituents of Lactuca indica L. Arch. Pharm. Res. 2008, 31, 983-988.
9. Kim, Ki Hyun; Jin, Mi Rim; Choi, Sang Zin; Son, Mi Won; Lee, Kang Ro. Three new ent-kaurane diterpenoids from the seeds of Pharbitis nil. Heterocycles 2008, 75, 1447-1455.
8. Kim, Ki Hyun; Choi, Sang Un; Park, Ki Moon; Seok, Soon Ja; Lee, Kang Ro. Cytotoxic constituents of Amanita subjunquillea. Arch. Pharm. Res. 2008, 31, 579-586.
7. Lee, Kyu Ha; Yang, Min Cheol; Kim, Ki Hyun; Kwon, Hak Cheol; Choi, Sang Un; Lee, Kang Ro. A new phenolic amide from the roots of Paris verticillata. Molecules 2008, 13, 41-45.
6. Yu, Byung Chul; Yang, Min Cheol; Lee, Kyu Ha; Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro. Arch. Pharm. Res. 2007, 30, 1471-1475.
5. Yang, Min Cheol; Kim, Sung Min; Lee, Kyu Ha; Kim, Ki Hyun; Lee, Kang Ro. A new sesquiterpene glycoside from the aerial parts of Saussurea triangulata. Molecules 2007, 12, 2270-2276.
4. Kim, Ki Hyun; Kim, Young Ho; Lee, Kang Ro. Isolation of quinic acid derivatives and flavonoids from the aerial parts of Lactuca indica L. and their hepatoprotective activity in vitro. Bioorg. Med. Chem. Lett. 2007, 17, 6739-6743.
3. Yang, Min Cheol; Lee, Kyu Ha; Kim, Ki Hyun; Choi, Sang Un; Lee, Kang Ro. Lignan and terpene constituents from the aerial parts of Saussurea pulchella. Arch. Pharm. Res. 2007, 30, 1067-1074.
2. Kim, Do Hoon; Yang, Min Cheol; Lee, Kyu Ha; Kim, Ki Hyun; Lee, Kang Ro. Phenolic constituents of Althaea rosea Canival. Kor. J. Pharmacogn. 2007, 38, 222-226.
1. Yu, Byung Chul; Yang, Min Cheol; Lee, Kyu Ha; Kim, Ki Hyun; Lee, Kang Ro. Norsesquiterpene and steroid constituents of Humulus japonicus. Nat. Prod. Sci. 2007, 13, 332-336.
특허
항염증 활성 조성물 및 이를 포함하는 염증 질환예방 또는 치료용 약학적 조성물, 출원일: 2014.06.10, 특허 등록: 2016.01.07 (10-2014-0070369), 농촌진흥청
조골세포 분화를 촉진하며 지방세포 분화를 억제하는 신규화합물 그 제조방법 및 그 응용, 출원일 2017.05.12, 특허 등록: 2018.09.05 (10-2017-0059133; 10-1897726), 성균바이오텍
뽕나무버섯부치 추출물 또는 그의 분획물을 포함하는 염증성 위장관 질환의 예방 또는 치료용 조성물, 출원일 2017.02.24
야관문 추출물의 분획물을 포함하는 암의 예방 또는 치료용 약학적 조성물, 출원일 2018.01.12 특허 등록: 2019.11.29 (10-2018-0004289; 10-2052516호), 중앙대학교 산학협력단
말톨, 이소소이아말로사이드 I 또는 이들의 혼합물을 유효성분으로 함유하는 아토피성 피부염 예방 또는 치료용 조성물, 출원일 2018.05.17 특허 등록: 2018.12.28 (10-2018-0056547; 10-1935371), 부산대학교 산학협력단, 성균관대학교 산학협력단
흰개미-연관 Actinomadura sp. RB99로부터 수득된 사이클린 트리펩타이드 나탈렌아미드 A-C, 출원일 2018.11.21 (출원번호 : 10-2018-0144664)
신규 화합물 및 이를 유효성분으로 함유하는 암의 예방 또는 치료용 조성물, 출원일 2019.10.24 (출원번호: 10-2019-0132722); 우선권번호 [KR 10-2019-0063526 (2019.05.30)], 특허 등록: 2021.12.01 (10-2336045호)
사이클릭 트리펩타이드, 이의 제조 방법, 및 이를 포함하는 미백용 조성물, 출원일 2019.09.05 (출원번호 : 10-2019-0109976) 등록일 : 2020.03.23 (등록번호 : 10-2094220)
미국 특허 등록 – Novel compound promoting osteoblast differentiation and inhibiting adipocyte differentiation, preparation method thereof and application thereof, 출원일 2018.11.09 (출원번호 : US 16/300,086), WO/2017/209410, 특허 등록: 2019.12.03, US 10,494,356 B2)
일본 특허 등록 – Novel compound promoting osteoblast differentiation and inhibiting adipocyte differentiation, preparation method thereof and application thereof, JP2019521091 특허 등록: 2019.10.25, 6605760)
신규 폴리페놀 화합물 및 이를 유효성분으로 함유하는 항진균용 조성물, 출원일 2020.05.14 (출원번호 : 10-2020-0057720).
산자나무 열매 추출물을 유효성분으로 하는 골대사 질환 예방 또는 치료용 조성물, 출원일 2020.09.07 (출원번호 : 10-2020-0113907).
6-펜틸-α-피론을 유효성분으로 포함하는 항진균 조성물, 출원일 2020.09.10 출원번호 : 10-2020-0116150); 특허 등록: 2023.9.25 (10-2584548호)
페날레논 유도체를 유효성분으로 포함하는 숙취해소용 조성물, 출원일 2020.06.02 출원번호 : 10-2020-0066318); 특허 등록: 2022.09.21 (10-2447255호)
항균 작용 및 에너지 하베스팅이 가능한 깔창, 출원일 : 2021-11-10, 출원번호 : 10-2021-0153733. 등록일 : 2023.09.21 (등록번호 : 10-2583150)
흑생강(Kaempferia parviflora) 추출물로부터 분리된 화합물을 포함하는 미백기능성 조성물 출원일: 2021-11-11, 출원번호 : 10-2021-0155179.
미국 특허 등록 – NOVEL COMPOUNDS AND METHOD OF PREVENTING OR TREATING CANCER USING THE SAME, 출원일 2020.05.20 (출원번호 : US 16/879,030), 국내우선권번호(우선일): 10-2019-0063526 (2019.05.30), 국내우선권번호(우선일): 10-2019-0132722 (2019.10.24), 특허 등록: 2021.11.09, US 11,168,092 B2
느릅나무로부터 분리한 신규 화합물, 출원일 2019.07.17 (출원번호: 10-2019-0086667); 특허 등록: 2021.11.08 (10-2325530호)
식물성 인돌알칼로이드 배당체를 포함하는 피부 개선용 조성물, 출원일: 2022-09-28, 출원번호 : 10-2022-0123813.
항균 활성 부여 가능한 치과용 핸드피스 냉각수 공급장치, 출원일: 2022-09-28, 출원번호 : 10-2022-0123537.
폐 오가노이드 모델 기반 SARS-CoV-2 예방 또는 치료용 약물의 스크리닝 방법. 출원일: 2023-02-28, 출원번호 : 10-2023-0026472.
잎갈나무 또는 구즈베리 추출물 또는 이로부터 분리된 화합물을 포함하는 피부노화방지용 조성물. 출원일: 2023-03-08, 출원번호 : 10-2023-0030356.
천연 분자로부터 유래된 유기물-금속 복합체 박막 보호층 및 이의 제조 방법. 출원일: 2023-08-28, 출원번호 : 10-2023-0112528. 미국
침향나무로부터 분리된 화합물을 포함하는 항균용, 항산화용 또는 항염증용 조성물. 출원일: 2024-02-22, 출원번호 : 10-2024-0025990.
버섯 바이오매스의 화학 개질을 통한 고비표면적 및 고성능 에너지 저장 소재 제조 방법. 출원일: 2024-03-08, 출원번호 : 10-2024-0032960.
디아릴헵타노이드 화합물을 포함하는 퇴행성 신경질환의 예방, 개선 또는 치료용 조성물. 출원일: 2024-03-12, 출원번호 : 10-2024-0034493.