中研院原分所 表面奈米結構實驗室
Surface Nanostructure Lab
Research Highlights
My primary research interest is to discover or create an ensemble of nanostructures with specific size, shape, and arrangement on specific positions in space. This subject is considered to be one the most fundamentally important issues in the exploration of nanoscience and realization of nanotechnology. My group has been exploring and exploiting the concept of ‘constrained self-organization’, which means to impose a set of constraining rules on a particle self-organization process in order to select a small desired subgroup from numerous possible outcomes of the process. The concept is attractive for realizing the dream of nanotechnology, i.e., to be able to quickly manipulate materials on the atomic scale, because ‘constrained self-organization’ is intrinsically a massive parallel process that is necessary for any viable technology aimed to create a large array of identical nanostructures with atomic scale precision in a reasonable time scale.
In the past twenty years, my group and collaborators have discovered several cases to demonstrate the concept of ‘constrained self-organization’ using the self-assembly of atoms and molecules on single-crystal surfaces and the self-organization of anodic aluminum oxide (AAO) nanochannels as platforms. Applying the same fascinating concept of ‘constrained self-organization’, we have also used arrays of AAO nanochannels to grow arrays of Ag-nanoparticles exhibiting large/uniform surface enhanced Raman scattering (SERS) activity as well as arrays of Ag and Au nanowires exhibiting unique physical properties of metamaterials. Highlights of these examples are described as follows.
1. Discovery of magic-number cluster of atoms and molecules on surfaces
2. Fabrication and applications of anodic aluminum oxide (AAO) nanochannels with custom-designed geometry
3. Fabrication and applications of Ag-nanoparticle arrays with large and uniform surface enhanced Raman scattering (SERS) activity
4. Rapid antibiotic susceptibility testing of bacteria from patients’ blood culture via assaying bacterial metabolic response using SERS
Rapid antibiotic susceptibility testing of bacteria from patients’ blood via assaying bacterial metabolic response with surface-enhanced Raman spectroscopy
Scientific Reports 2020
World Journal of Microbiology and Biotechnology 2023