Dr. Huan-Cheng Chang - Gold/Diamond Nanohybrids for Quantum Sensing Applications

Gold/Diamond Nanohybrids for Quantum Sensing Applications

Pei-Chang Tsai,¹ Oliver Y. Chen,¹ Yan-Kai Tzeng,¹ Yuen Yung Hui,¹ Jiun You Guo,² Chih-Che Wu,² Ming-Shien Chang,*^,1 and Huan-Cheng Chang*^,1,3

¹Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan

²Department of Applied Chemistry, National Chi Nan University, Puli, Nantou 545, Taiwan

³Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan

EPJ Quantum Technol. 2, 19 (2015).

Recent advances in quantum technology have demonstrated the potential use of negatively charged nitrogen-vacancy (NV–) centers in diamond for temperature and magnetic sensing at sub-cellular levels. Fluorescent nanodiamonds (FNDs) containing high-density ensembles of NV– centers are appealing for such applications because they are inherently biocompatible and non-toxic. Here, we show that FNDs conjugated with gold nanorods (GNRs) are useful as a combined nanoheater and nanothermometer for highly localized hyperthermia treatment using near-infrared (NIR) lasers as the heating source. A temperature rise of ~10 K can be readily achieved at a NIR laser power of 0.4 mW in cells. The technique is compatible with the presence of static magnetic fields and allows for simultaneous temperature and magnetic sensing with nanometric spatial resolution. To elucidate the nanoscale heating process, numerical simulations are conducted with finite element analysis, providing an important guideline for the use of this new tool for active and high-precision control of temperature under diverse environmental conditions. [link], [Fullfile]

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