"Chromosomes are stick-shaped structures in the middle of each cell in the body. Each cell has 46 chromosomes grouped in 23 pairs. When a chromosome is abnormal, it can cause health problems in the body. Abnormal chromosomes most often happen as a result of an error during cell division. Chromosome abnormalities often happen due to one or more of these:
Source Citation: “Medical Genetics: How Chromosome Abnormalities Happen.” Medical Genetics: How Chromosome Abnormalities Happen - Health Encyclopedia - University of Rochester Medical Center, University of Rochester Medical Center, 2019, www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=90&ContentID=P02126.