研究業績（主な研究論文）

詳細なものはリサーチマップでご確認お願いします。Researchmap

1. Akihiro Tsuboi, Hamida Khanom, Riki Kawabata, Takanori Matsui, Shigeru Murakami, Takashi Ito.  Taurine Ameliorates Cellular Senescence Associated with an Increased Hydrogen Sulfide and a Decreased Hepatokine, Igfbp-1, in Ccl4-Induced Hepatotoxicity in Mice. Redox Biology, 03640.  (2025) リンク 

1. Takashi Ito* and Shigeru Murakami.　Taurine deficiency associated with dilated cardiomyopathy and aging. (Review) Journal of Pharmacological Sciences

Volume 154, Issue 3, March 2024, Pages 175-181 リンク 

2. 堀田拓馬、坪井耀大、伊藤崇志. コオロギの食餌の違いによるタウリンおよびアミノ酸含量への影響. 福井県立大学論集 60, 109-116 (2024)　PDFが開きます 

3. 前川栄治, 苧玉真生, 坪井耀大, Hamida Khanom, 坪谷香菜絵, Joanna Bajerska, 村上茂, 伊藤崇志. ナツメ果実搾りかすの健康機能性及び食味性向上に資する菓子素材としての有用性. 福井県立大学論集 60, 117 (2024)　PDFが開きます 

4. 伊藤崇志. タウリン欠乏と加齢の関連性について. タウリンリサーチ 10(1) 20-23. 2024年9月

1. Mao Odama, Eiji Maegawa, Kohsuke Suzuki, Yujiro Fujii, Reika Maeda, Shigeru Murakami, and Takashi Ito*.　Effects of Betulinic Acid on the Proliferation, Cellular Senescence, and Type 1 Interferon-Related Signaling Pathways in Human Dermal Fibroblasts. Journal of Agricultural and Food Chemistry (2023)　リンク 

2.  伊藤 崇志, 村上 茂. タウリンによる多臓器連関の調節の可能性. タウリンリサーチ 9(1) 20-22 2023年9月  リンク 

1. Nguyen K, Maegawa E, Murakami S, Schaffer S, Ito T*. N-Chlorotaurine Reduces the Lung and Systemic Inflammation in LPS-Induced Pneumonia in High Fat Diet-Induced Obese Mice. Metabolites 12(4), 349 (2022)

2. Murakami S, Funahashi K, Tamagawa N, Ning M, Ito T. Taurine Ameliorates Streptozotocin-Induced Diabetes by Modulating Hepatic Glucose Metabolism and Oxidative Stress in Mice. Metabolites 12(6), 524 (2022)

3. Nguyen K, Murakami S, Schaffer S, Ito T*. Examination of taurine chloramine and taurine on LPS-induced acute pulmonary inflammation in mice. Adv Exp Med Biol. 1370, 23-39 (2022)

4. Ito T*, Nguyen K, Maruyama C, Hamano Y, Murakami S, Schaffer S. Bioavailability of tauropine after oral ingestion in mouse. Adv Exp Med Biol.1370, 137-142 (2022)

5. 伊藤崇志*．葛由来成分プエラリンによる皮膚細胞の老化抑制効果．フレグランスジャーナル（2022）

6. 伊藤崇志*．N―クロロタウリンのLPS 誘発性肺炎および筋萎縮に対する効果．タウリンリサーチ,8,5-6 (2022)

1. Tsubotani K, Maeyama S, Murakami S, Schaffer SW, Ito T*. Taurine suppresses liquid-liquid phase separation of lysozyme protein. Amino Acids. (2021)

2. Kamiya Y, Odama M, Mizuguti A, Murakami S, Ito T*. Puerarin blocks the aging phenotype in human dermal fibroblasts. Plos One. (2021)

3. Murakami S*, Hirazawa C, Ohya T, Yoshikawa R, Mizutani T, Ma N, Moriyama M, Ito T, Matsuzaki C. The Edible Brown Seaweed Sargassum horneri (Turner) C. Agardh Ameliorates High-Fat Diet-Induced Obesity, Diabetes, and Hepatic Steatosis in Mice. Nutrients, 13,551(2021)

4.  伊藤崇志*、坪谷香菜絵、前山小百合、村上茂．タウリンの液-液相分離に対する作用の検討．タウリンリサーチ,7, 17-19 (2021)

5. 伊藤崇志*．タウリンクロラミンの新型コロナウイルス感染症（COVID-19）治療薬としての期待．タウリンリサーチ,7, 28-31 (2021)

1. Nguyen K, Ito S, Maeyama S, Schaffer S, Murakami S, Ito T*. In vivo and In vitro study of N-methyltaurine on pharmacokinetics and anti-muscle atrophic effect in mice. ACS Omega, 5, 11241-11246 (2020)

2. Komatsuzawa R, Miyazaki T, Ohmori H, Maruyama C, Schaffer S, Murakami S, Ito T*. Evaluation of taurine content on skeletal muscle of exercised rats using MALDI-TOF MS imaging analysis. J Phys Fitness Sports Med, 9, 1-7 (2020)

3. NGUYEN HOANG KHANH、前山小百合、村上茂、伊藤崇志*．海藻に含まれるタウリン誘導体の体内動態の検討．タウリンリサーチ,6, 16-17 (2020)

4. 伊藤崇志．タウリントランスポーター遺伝子に関する遺伝子変異と拡張型心筋症との関連．タウリンリサーチ,6,39-42 (2020)

1. Ito T*, Murakami S, Schaffer S. Taurine-Conjugated Metabolites in Hearts. Adv Exp Med Biol. 1155, 523-529 (2019)

2. 伊藤崇志*、宮下晶惠、伊藤駿太、村上茂．海産物中タウリン誘導体の薬理作用．タウリンリサーチ,5, 42-44 (2019)

1.  Ito T*, Murakami S, Schaffer S. Pathway Analysis of a Transcriptome and Metabolite Profile to Elucidate a Compensatory Mechanism for Taurine Deficiency in the Heart of Taurine Transporter Knockout Mice. J Multidisciplinary Scientific Journal, 1(1), 57-70 (2018)

2.  Ito T*, Hanahata Y, Kine K, Murakami S, Schaffer S. Tissue taurine depletion induces profibrotic pattern of gene expression and causes aging-related cardiac fibrosis in heart in mice. Biol Pharm Bull, 41, 1561-1566 (2018)

3. Murakami S, Ono A, Kawasaki A, Takenaga T, Ito T. Taurine attenuates the development of hepatic steatosis through the inhibition of oxidative stress in a model of nonalcoholic fatty liver disease in vivo and in vitro. Amino Acids, 50, 1279-1288 (2018)

4.  Ito T*, Nakanishi Y, Yamaji N, Murakami S, Schaffer S. Induction of growth differentiation factor 15 in skeletal muscle of old taurine transporter knockout mouse. Biol Pharm Bull., 41, 435-439 (2018)

5.  Ito T*, Okazaki K, Nakajima D, Shibata D, Murakami S, Schaffer S. Mass spectrometry-based metabolomics to identify taurine-modified metabolites in heart. Amino Acids, 50,117-124 (2018)

6. 伊藤崇志*；メタボローム解析による心臓におけるタウリン抱合物質の探索．タウリンリサーチ,4, 17-18 (2018)