Publications

Benjamin T Jones, Jaeil Han, He Zhang, Robert E Hammer, Bret M Evers, Dinesh Rakheja, Asha Acharya, Joshua T Mendell. Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Genes & Development. 2023 Auguest 08, Published Advanced online.

Jaeil Han and Joshua T. Mendell. MicroRNA turnover: a tale of tailing, trimming, and targets. Trends in Biochemical Sciences. 2023 January 01, Vol. 48; Issue 1, P26039

Jaeil Han, Collette A. LaVigne, Benjamin T. Jones, He Zhang, Frank Gillett, and Joshua T. Mendell. A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming. Science. 2020 December 18; Vol. 370; Issue 6523

         Spotlight: “To Degrade a MicroRNA, Destroy Its Argonaute Protein” Mol Cell. 2021

         Featured: “Breaking it down: How cells degrade unwanted microRNAs” ScienceDaily

Michael N. Trinh, Michael S. Brown, Joseph L. Goldstein, Jaeil Han, Gonçalo Vale, Jeffrey G. McDonald, Joachim Seemann, Joshua T. Mendell, and Feiran Lu. Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine. Proceedings of the National Academy of Sciences of the USA. 2020 July 20; 2010682117

Hema Manjunath, He Zhang, Frederick Rehfeld, Jaeil Han, Tsung-Cheng Chang, and Joshua T. Mendell. Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection. Cell Reports. 2019 December 3; 29, 3134–3146

Alexandra N. Marshall, Jaeil Han, Minseon Kim, and Ambro van Hoof. Conservation and diversification of Ski7 in eukaryotes through changes in alternative splicing and gene duplication. Proceedings of the National Academy of Sciences of the USA. 2018 July 2; 201801997

Jaeil Han and Ambro van Hoof. The RNA exosome channeling and direct access conformations have distinct in vivo functions. Cell Reports. 2016 Sep 20;16(12):3348-58

Tripti Anandan*, Jaeil Han*, Heather Baun, Seeta Nyayapathy, Jacob T. Brown, Rebekah L. Dial, Juan A. Moltalvo, Min-Seon Kim, Seung Hwan Yang, Donald R. Ronning, Robert N. Husson, Joowon Suh & Choong-Min Kang. Phosphorylation regulates mycobacterial proteasome. Journal of Microbiology. 2014 Sep; 52(9): 743-54 (*co-first authors)