Publications

2025 Publications

• Naeimi Torshizi, SR; Yousefi Seyf, J; Najafi, R; Ventura, D; Mahdavinezhad, A; Afshar, S; Azizi Jalilian, F; Shojaeian, A; Amini, R; Pecic, S. Magnetic targeting enhances nanostructured covalent organic framework-doxorubicin cellular uptake in triple-negative breast cancer: A model for receptor-deficient cancers. International Journal of Biological Macromolecules (2025), 323, 147169.

• Carr, D; Gunari, S; Gorostiza, G; Mercado, M; Pavana, L; Duong, L; Gomez, K; Salinas, S; Garcia, C; Tsang, A; Morisseau, C; Hammock, BD; Pecic, S; Kandasamy, R. Synthesis and evaluation of isoquinolinyl and pyridinyl-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase to alleviate orofacial hyperalgesia in the rat. Biochemistry and Biophysics Reports (2025) 42, 102009. 

• Yuan, C; Tsang, A; Berumen, M; Rodriguez, A; Yun, F; Mesic, A; Olivares, A; Dubon, L; Nguyen, A; Pavana, L; Mercado, M; Gorostiza, G; Morisseau, C; Hammock, BD; Kandasamy, R; Pecic, S. Structure-activity relationship studies and pharmacological evaluation of 4-phenylthiazoles as dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorganic & Medicinal Chemistry (2025), 118112.

• Katz, FS; Trakht, I; Pecic, S; Rinderspacher, A; Schneider, A; Landry, DW; Stojanovic, MN. Conformational Constraint For Prevention of Aging of Organophosphate-Inhibited Acetylcholinesterase. ChemBioChem (2025), e202500186.

• Weng, X; Gonzalez, M; Angelia, J; Piroozmand, S; Jamehdor, S; Behrooz, AB; Latifi-Navid, H; Ahmadi, M; Pecic, S. Lipidomics-driven drug discovery and delivery strategies in glioblastoma. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2025) 1871 (3), 167637.

2024 Publications

• Mafi, S; Dehghani, M; Khalvati, B; Abidi, H; Ghorbani, M; Jalali, P; Whichelo, R; Salehi, Z; Markowska, A; Reyes, A; Pecic, S; Los, M; Ghavami, S; Nikseresht, M. Targeting PERK and GRP78 in Colorectal Cancer: Genetic Insights and Novel Therapeutic Approaches. European Journal of Pharmacology (2024), 176899.

• Carr, D; Chin, C; Chacon, T; Herawi, MK; Gonzalez, M; West, R; Morisseau, C; Hammock, BD; Pecic, S; Kandasamy, R. 4-phenyl-thiazole-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase do not alleviate orofacial inflammatory pain in female rats. BBA Advances 6 (2024), 100119.

• Angelia, J; Duong, L; Yun, F; Mesic, A; Yuan, C; Carr, D; Gunari, S; Hudson, PK; Morisseau, C; Hammock, BD; Kandasamy, R; Pecic, S. Quinolinyl-based multitarget-directed ligands with soluble epoxide hydrolase and fatty acid amide hydrolase inhibitory activities: Synthetic studies and pharmacological evaluations. Heliyon (2024), 10 (11).

• Shojaeian, A; Naeimi Torshizi, SR; Parsapasand, MS; Amjad, ZS; Khezrian, A; Alibakhshi, A; Yun, F; Baghaei, K; Amini, R; Pecic, S. Harnessing exosomes in theranostic applications: advancements and insights in gastrointestinal cancer research. Discover Oncology 15, 162 (2024).

• Azusada, T; Baybay, E; Chi, J; Dole, P; Gonzalez, N; Jaramillo, E; Nguyen, T; Pivaral, A; Rodriguez, G; Zavala, J; Zayed, H; Gaspar, A; Andino, S; Nguyen, K; Pintea, S; Nguyen, H; Hudson, PK; Pecic, S. One-step microwave enhanced synthesis, biological evaluation, and molecular modeling investigations of donepezil analogs as acetylcholinesterase inhibitors. Results in Chemistry (2024), 7, 101226.

2023 Publications

• Zarrabi, A; Perrin, D; Kavoosi, M; Sommer, M; Sezen, S; Mehrbod, P; Bhushan, B; Machaj, F; Rosik, J; Kawalec, P; et al. Rhabdomyosarcoma: Current Therapy, Challenges, and Future Approaches to Treatment Strategies. Cancers (2023), 15, 5269.

• Kandasamy, R. and S. Pecic, Chapter 13 - Treatment of pain with dual fatty acid amide hydrolase (FAAH) enzyme and human soluble epoxide hydrolase (sEH) enzyme inhibitors: Interlinking the endocannabinoid system, in Neurobiology and Physiology of the Endocannabinoid System, V.B. Patel, V.R. Preedy, and C.R. Martin, Editors. 2023, Academic Press. p. 175-187.

• Alizadeh, J; da Silva Rosa, SC; Weng, X; Jacobs, J; Lorzadeh, S; Ravandi, A; Vitorino, R; Pecic, S; Zivkovic, A; Stark, H; Shojaei, S; Ghavami, S. Ceramides and Ceramide Synthases in Cancer: Focus on Apoptosis and Autophagy. European Journal of Cell Biology (2023),151337.

• Stec, J; Xie, S; Alshukri, L; Kang, GJ; Hudson, PK; Pecic, S. Convenient synthesis and in vitro activity of oxalyl bis(benzenesulfonylhydrazides) and related compounds. Results in Chemistry (2023), 5, 100860.

• Angelia, J; Weng, X; Solomatov, A; Chin, C; Fernandez, A; Hudson, PK; Morisseau, C; Hammock, BD; Kandasamy, R; Pecic, S. Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior. Prostaglandins & Other Lipid Mediators (2023), 164, 106702.

2022 Publications

• ​Naeimi, R; Najafi, R; Molaei, P; Amini, R; Pecic, S. Nanoparticles: The future of effective diagnosis and treatment of colorectal cancer? European Journal of Pharmacology (2022), 175350.

• Eshraghi, M; Ahmadi, M; Afshar, S; Lorzadeh, S; Adlimoghaddam, A; Rezvani Jalal, N; West, R; Dastghaib, S; Igder, S; Torshizi, SRN; Mahmoodzadeh, A; Mokarram, P; Madrakian, T; Albensi, BC; Łos, MJ; Ghavami, S; Pecic, S. Enhancing autophagy in Alzheimer's disease through drug repositioning. Pharmacology & Therapeutics (2022), 237, 108171.

• Waters, K;  Nguyen, D;  Hernandez, L;  Vu, K;  Fry-Petit, A;  Pecic, S; Haan, JL: The electrochemical oxidation of butanediol isomers in an alkaline direct liquid fuel cell. Journal of Power Sources (2022), 535, 231401.

• Stec, J; Pecic, S. Facile synthesis of the fungus-derived natural products: N,N′-dipalmitoleyl urea (C16:1) and N,N′-dioleyl urea (C18:1), Natural Product Research (2022), 36 (8), 2158-2165.

• Makarian, M; Gonzalez, M; Salvador, SM; Lorzadeh, S; Hudson, PK; Pecic, S. Synthesis, kinetic evaluation and molecular modeling studies of donepezil-based acetylcholinesterase inhibitors. Journal of Molecular Structure, (2022), 1247, 131425.

2021 Publications

• Wilt, S; Kodani, S; Valencia, L; Hudson, PK; Sanchez, S; Quintana, T; Morisseau, C; Hammock, B. D.;  Kandasamy, R; Pecic, S. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorganic & Medicinal Chemistry, (2021), 51, 116507.

• Coonahan ES, Yang KA, Pecic S, De Vos M, Wellems TE, Fay MP, Andersen JF, Tarning J, Long CA. Structure-switching aptamer sensors for the specific detection of piperaquine and mefloquine. Science Translational Medicine, (2021);13(585).

2020 Publications

• Ahmadi, M; Amiri, S; Pecic, S; Machaj, F; Rosik, J; Łos, MJ; Alizadeh, J; Reza Mahdian, R; da Silva Rosa, SC; Schaafsma, D; Shojaei, S; Madrakian, T; Zeki, AA; Ghavami, S. Pleiotropic Effects of Statins: a Focus on Cancer. BBA Molecular Basis of Disease, (2020), 1866: 165968. 

• Wilt, S; Kodani, S; Thanh LN ; Nguyen, L; Nghi, V; Ly, T; Rodriguez, M; Hudson, P; Morisseau, C, Hammock, BD; Pecic, S. Development of multitarget inhibitors for the treatment of pain: design, synthesis, biological evaluation and molecular modeling studies. Bioorganic Chemistry, (2020), 103: 104165.

• Lu, R; Zeki, A; Ram-Mohan, S; Nguyen, N; Bai, Y; Chmiel, K; Pecic, S; Ai, X; Krishnan, R; Ghosh, C. Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins. Frontiers in Pharmacology, (2020), 11: 469.

• Wilt, S; Rodriguez, M; Thanh LN; Baltodano, EV; Salas, A; Pecic, S. ​Design, Microwave‐Assisted Synthesis, Biological Evaluation and Molecular Modeling Studies of 4‐Phenylthiazoles as Potent Fatty Acid Amide Hydrolase Inhibitors. Chemical Biology & Drug Design, (2020), 95:534–547. 

2019 Publications

• Pecic, S; Milosavic, N; Rayat, G; Maffei, A; Harris, PE. A novel optical tracer for VMAT2 applied to live cell measurements of vesicle maturation in cultured human β-cells. Scientific Reports, (2019) 9:5403.

Publications from Columbia University Medical Center (Postdoctoral Research)

• ​Pecic, S; Zeki, AA; Xu, X; Jin, GY; Zhang, S; Kodani, S; Halim, M; Morisseau, C; Hammock, BD; Deng, SX. Novel piperidine- derived amide sEH inhibitors as mediators of lipid metabolism with improved stability Prostaglandins and Other Lipid Mediators, (2018), 136, 90-95.

• Katz, FS; Pecic, S; Schneider, L; Zhu, Z; Hastings, A; Luzac, M; Macdonald, J; Landry, DW; Stojanovic, MN. New therapeutic approaches and novel alternatives for organophosphate toxicity Toxicology Letters (2018), 291, 1-10.

• Yang, KA; Chun, H; Zhang, Y; Pecic, S; Nakatsuka, N; Andrews, AM; Worgall, TS; Stojanovic, MN. High- Affinity Nucleic- Acid- Based Receptors for Steroids ACS Chemical Biology (2017), 12(12), 3103-3112.

• ​Tang, J; Ma, D; Pecic, S; Huang, C; Zheng, J; Li, J; Yang, R. Noninvasive and Highly Selective Monitoring of Intracellular Glucose via a Two- Step Recognition- Based Nanokit Analytical Chemistry (Washington, DC, United States) (2017), 89(16), 8319-8327.

• Terzic, N; Konstantinovic, J; Tot, M; Burojevic, J; Djurkovic-Djakovic, O; Srbljanovic, J; Stajner, T; Verbic, T; Zlatovic, M; Machado, M; Albuquerque, IS; Prudencio, M; Sciotti, RJ; Pecic, S; D'Alessandro, S; Taramelli, D; Solaja, BA. Reinvestigating Old Pharmacophores: Are 4- Aminoquinolines and Tetraoxanes Potential Two- Stage Antimalarials? Journal of Medicinal Chemistry (2016), 59(1), 264-281.

• Katz, FS; Pecic, S; Tran, TH; Trakht, I; Schneider, L; Zhu, Z; Ton-That, L; Luzac, M; Zlatanic, V; Damera, Macdonald, J; Landry, DW; Tong, L; Stojanovic, MN. Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates ChemBioChem (2015), 16(15), 2205-2215. (Featured on the cover of the October Issue)

• Yang, KA; Barbu, M; Halim, M; Pallavi, P; Kim, B; Kolpashchikov, DM; Pecic, S; Taylor, S; Worgall, TS; Stojanovic, MN. Recognition and sensing of low- epitope targets via ternary complexes with oligonucleotides and synthetic receptors Nature Chemistry (2014), 6(11), 1003-1008.

• Pecic, S; Pakhomova, S; Newcomer, ME; Morisseau, C; Hammock, BD; Zhu, Z; Rinderspacher, A; Deng, SX. Synthesis and structure-activity relationship of piperidine- derived non- urea soluble epoxide hydrolase inhibitors Bioorganic & Medicinal Chemistry Letters (2013), 23(2), 417-421.

• Pecic, S; Deng, SX; Morisseau, C; Hammock, BD; Landry, DW. Design, synthesis and evaluation of non- urea inhibitors of soluble epoxide hydrolase Bioorganic & Medicinal Chemistry Letters (2012), 22(1), 601-605.

Publications from Hunter College, CUNY (Doctoral Research)

• Pecic, S; McAnuff, MA; Harding, WW. Nantenine as an acetylcholinesterase inhibitor: SAR, enzyme kinetics and molecular modeling investigations Journal of Enzyme Inhibition and Medicinal Chemistry (2011), 26(1), 46-55.

• Pecic, S; Makkar, P; Chaudhary, S; Reddy, BV; Navarro, HA; Harding, WW. Affinity of aporphines for the human 5- HT2A receptor: Insights from homology modeling and molecular docking studies Bioorganic & Medicinal Chemistry (2010), 18(15), 5562-5575.

• LeGendre, O; Pecic, S; Chaudhary, S; Zimmerman, SM; Fantegrossi, WE; Harding, WW. Synthetic studies and pharmacological evaluations on the MDMA ( Ecstasy') antagonist nantenine Bioorganic & Medicinal Chemistry Letters (2010), 20(2), 628-631.

• Chaudhary, S; Pecic, S; Le Gendre, O; Navarro, HA; Harding, WW. (±) - Nantenine analogs as antagonists at human 5- HT2A receptors: C1 and flexible congeners Bioorganic & Medicinal Chemistry Letters (2009), 19(9), 2530-2532.

• Chaudhary, S; Pecic, S; Le Gendre, O; Harding, WW. Microwave-assisted direct biaryl coupling: first application to the synthesis of aporphines Tetrahedron Letters (2009), 50(20), 2437-2439. 

• Chaudhary, S; Thomas, V; Todaro, L; LeGendre, O; Pecic, S; Harding, WW. New drimane sesquiterpenoids from Tidestromia oblongifolia Natural Product Communications (2008), 3(11), 1747-1750.