Contents

Reviews

Gasotransmitters and Fine Bubbles: Emerging Strategies for Controlled Gas Delivery and Cell Culture Applications 

TOYOFUMI HIRAKAWA, DAICHI URUSHIYAMA, KOHEI MIYATA, SHIN’ICHIRO YASUNAGA, FUSANORI YOTSUMOTO and SHINGO MIYAMOTO

Anticancer Research August 2026, 46 (8) 4601-4609; DOI: https://doi.org/10.21873/anticanres.18317

Pitfalls and Emerging Trends in AI-driven Pathological Analysis of Metastatic Brain Tumors 

MITSUGU FUJITA, SHIGEAKI NAWA, EIJI ITO, TORU NAGASAKA, SHUNICHIRO KURAMITSU, KIMIHIRO YAMASHITA, SUSUMU NAKATA and MASASUKE OHNO

Anticancer Research August 2026, 46 (8) 4611-4618; DOI: https://doi.org/10.21873/anticanres.18318

Effects of Rehabilitation Before and After Pulmonary Resection: A Literature Review 

HARUKI MANIWA and SATOSHI OHNO

Anticancer Research August 2026, 46 (8) 4619-4626; DOI: https://doi.org/10.21873/anticanres.18319

Experimental Studies

Analysis for IL-22/ IL-22BP Axis and Cell Adhesion Molecules in Advanced Colorectal Cancer 

NAOHIRO YOSHIDA, MASAYUKI TAKAMATSU, KENTA TAKAKI, KAHORI HISADA, FUMIKI KOGA, MAAKO KIKUCHI, TAKAHIRO SHIGAKI, KENJI FUJIYOSHI, TAKAFUMI OHCHI, TAKEFUMI YOSHIDA, YUICHI GOTO, TARO ISOBE, NAOKI MORI, HISAMUNE SAKAI, TOMOYA SUDO, NOBUYA ISHIBASHI, TORU HISAKA and FUMIHIKO FUJITA

Anticancer Research August 2026, 46 (8) 4627-4637; DOI: https://doi.org/10.21873/anticanres.18320

Effect of Tolyl Modification on Celecoxib Related Structure: Molecular Features of MMP-interacting UTX-121 Derivatives 

KAZUTO OHKURA, ATSUSHI TABATA and YOSHIHIRO UTO

Anticancer Research August 2026, 46 (8) 4639-4647; DOI: https://doi.org/10.21873/anticanres.18321

Pyra–Metho–Carnil Suppresses CD73-associated Macrophage Infiltration in KRAS-mutant Colorectal Cancer 

TAKANORI KITAGUCHI, SEIMON ABE, TAICHI MATSUMOTO, KAZUMASA YOSHIDA, GEN MARUTA, HISANORI MAEOKA, SHUHEI ISHIKURA, YUSUKE ISHIDA, FUMIHITO HIRAI, MIKIKO AOKI, TOSHIHIRO HAMADA, KAZUHIKO NAKABAYASHI, KAZUHIRO KOIKAWA, MICHITAKA NAKANO, SENJI SHIRASAWA and TOSHIYUKI TSUNODA

Anticancer Research August 2026, 46 (8) 4649-4663; DOI: https://doi.org/10.21873/anticanres.18322

Extracellular Vesicles Derived from Heyndrickxia coagulans Lilac-01 Modulate Immune Responses In Vitro and Ex Vivo 

AKO KUDO, KIHIRO SHIMIZU, HIMEKA TSUDA, KENTA NIHASHI, KIMIKO MINAMIDA, AKIRA TAKAGURI, KEISUKE SATO, KEN-ICHI KOMATSU and KOJI WAKAME

Anticancer Research August 2026, 46 (8) 4665-4679; DOI: https://doi.org/10.21873/anticanres.18323

Leucine-rich KQLLL Motif Coordinates Secretion, Nuclear Localization, and Proliferation of Chitinase 3-like 1 

SIYUAN WANG, TAKANORI MINAGAWA, YUSUKE TOYODA, TAKAYUKI SADANAGA, SHIGEAKI SAITOH and EMIKO MIZOGUCHI

Anticancer Research August 2026, 46 (8) 4681-4687; DOI: https://doi.org/10.21873/anticanres.18324

Development of Novel Schiff Base–Tyrosine Kinase Inhibitor Conjugates that Enhance the Effects of ALA-PDT 

YUSEI SHINOHARA, CHIAKI ABE, YOSHIO ENDO, HISATSUGU YAMADA and YOSHIHIRO UTO

Anticancer Research August 2026, 46 (8) 4689-4698; DOI: https://doi.org/10.21873/anticanres.18325

Clinical Studies

Safety and Preliminary Efficacy of Personalized Neoantigen-pulsed Dendritic Cell Vaccination in Patients With Solid Tumors: An Interim Analysis 

RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, HIROSHI IBE, ERI OGUMA, AYA OHNO, KEIKO NAITO, YOICHIRO YOSHIDA, SEIJI NARIMIYA and SHIGENORI GOTO

Anticancer Research August 2026, 46 (8) 4699-4706; DOI: https://doi.org/10.21873/anticanres.18326

MUC5AC, CEACAM7, and DUOX2 Distinguish Colitis-associated Cancer from Sporadic Colorectal Cancer 

TETSUSHI KINUGASA, TAICHI MATSUMOTO, TOSHIYUKI OKADA, TOMOYA SUDO, MOTOI UCHINO, TATSUYA MANABE, EMIKO MIZOGUCHI, AKIHIKO KAWAHARA, JUN AKIBA, TOSHIYUKI TSUNODA and FUMIHIKO FUJITA

Anticancer Research August 2026, 46 (8) 4707-4717; DOI: https://doi.org/10.21873/anticanres.18327

Prognostic Factors in Patients Aged ≥80 Years With Stage II-III Gastric Cancer 

HIDEAKI KAKU, YUYA TANAKA, TARO ISOBE, JUNYA KIZAKI, NAOTAKA MURAKAMI, MASASHI NAKAGAWA, KOHEI SAISHO, YUICHI GOTO, TAKEFUMI YOSHIDA, NAOKI MORI, HISAMUNE SAKAI, TOMOYA SUDO, TORU HISAKA, NOBUYA ISHIBASHI, KEISHIRO AOYAGI and FUMIHIKO FUJITA

Anticancer Research August 2026, 46 (8) 4719-4726; DOI: https://doi.org/10.21873/anticanres.18328

Multidetector CT Versus ERCP for Preoperative Assessment of Longitudinal Extension of Distal Bile Duct Cancer 

YOHEI NAKAMA, RYUICHI KAWAHARA, YUSUKE ISHIDA, TATSUYUKI TONAN, MASAMICHI NAKAYAMA, YOSHIKI NAITO, FUMIHIKO FUJITA and TORU HISAKA

Anticancer Research August 2026, 46 (8) 4727-4734; DOI: https://doi.org/10.21873/anticanres.18329

Minimally Invasive Versus Open Liver Resection for HCC in the Posterosuperior Segments: A Propensity Score-matched Study 

HISAMUNE SAKAI, YUICHI GOTO, SHOGO FUKUTOMI, SHOICHIRO ARAI, RYUTA MIDORIKAWA, DAIKI MIYAZAKI, HIROTOSHI TSURU, MASANORI AKASHI, NOBUYA ISHIBASHI, FUMIHIKO FUJITA and TORU HISAKA

Anticancer Research August 2026, 46 (8) 4735-4744; DOI: https://doi.org/10.21873/anticanres.18330

Acupuncture for Taxane-induced Peripheral Neuropathy: A Randomized Controlled Trial 

SATOSHI OHNO, HARUHI INOKUCHI, DAICHI KASUYA, TAKAO TAKAHASHI and SATORU YAMAGUCHI

Anticancer Research August 2026, 46 (8) 4745-4753; DOI: https://doi.org/10.21873/anticanres.18331

　　Contents

3D-floating Culture for Cancer Research: A Mini-review
AKIKO FUKUYAMA, TAKANORI KITAGUCHI, KAZUMASA YOSHIDA, TAICHI MATSUMOTO, KAZUHIRO KOIKAWA, MICHITAKA NAKANO, GEN MARUTA, HISANORI MAEOKA, SHUHEI ISHIKURA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA
Anticancer Research August 2025, 45 (8) 3401-3408; DOI: https://doi.org/10.21873/anticanres.17702

Proteomic and Metabolomic Analyses of Adipose-derived Mesenchymal Stem Cell Exosomes and Culture Supernatants
TOYOFUMI HIRAKAWA, TAMOTSU KATO, YUMIKO NAKANISHI, DAICHI URUSHIYAMA, KOHEI MIYATA, TSUKASA BABA, HIROSHI OHNO, SHIN’ICHIRO YASUNAGA, FUSANORI YOTSUMOTO and SHINGO MIYAMOTO
Anticancer Research August 2025, 45 (8) 3409-3424; DOI: https://doi.org/10.21873/anticanres.17703

Combination of 3-(Trihydroxygermyl)propanoic Acid (THGP) and Lipopolysaccharide Promotes Macrophage Differentiation to M1, and Antitumor Activity
JUNYA AZUMI, TOMOYA TAKEDA, YASUHIRO SHIMADA, HISASHI ASO, HIROYUKI INAGAWA and TAKASHI NAKAMURA
Anticancer Research August 2025, 45 (8) 3425-3440; DOI: https://doi.org/10.21873/anticanres.17704

Molecular Characterization and Therapeutic Implications of MYD88 and CDKN2A in Primary CNS Lymphoma
RYOUTA TAOMOTO, MIKIKO AOKI, TOSHIYUKI ENOMOTO, TOORU INOUE, KAZUKI NABESHIMA, MAKOTO HAMASAKI and HIROSHI ABE
Anticancer Research August 2025, 45 (8) 3441-3450; DOI: https://doi.org/10.21873/anticanres.17705

Effect of Sulfonamide Group Modification on Celecoxib: Molecular Features of Matrix Metalloproteinase Interactive UTX-121 Derivative
KAZUTO OHKURA, ATSUSHI TABATA and YOSHIHIRO UTO
Anticancer Research August 2025, 45 (8) 3451-3457; DOI: https://doi.org/10.21873/anticanres.17706

Antioxidant Effects of Bidens Pilosa Extract Protect RAW 264.7 Cells from Cisplatin-induced Cytotoxicity
KIHIRO SHIMIZU, AKO KUDO, TOKO IIDA, KEISUKE SATO, AKIFUMI NAKATA, KENICHI KOMATU, KAZUKI TAKAI and KOJI WAKAME
Anticancer Research August 2025, 45 (8) 3459-3467; DOI: https://doi.org/10.21873/anticanres.17707

Nuclear Localization of Chitinase 3-like 1 Is a Novel Biomarker for Detecting the Early Stage of Inflammation-associated Dysplasia in the Oral Cavity
YUI TERATANI, TAKAYUKI SADANAGA, SIYUAN WANG, JINGO KUSUKAWA and EMIKO MIZOGUCHI
Anticancer Research August 2025, 45 (8) 3469-3478; DOI: https://doi.org/10.21873/anticanres.17708

Comparison of Comprehensive Genomic Profiling Testing “Ion Torrent Genexus Sequencer” With FoundationOne
KENJI FUJIYOSHI, RIE SUGIHARA, NAOKI MIYAMOTO, YORIKO WATANABE, TOMOYA SUDO, SANAE NUMATA, JUN AKIBA, HIDEYUKI ABE, YUKA ICHINOSE, KENJI INOUE, SHUICHI OZONO, TAKEHARU ONO, KENTARO ORIOKA, MASAKI KASHIHARA, RYOUSUKE KAJIWARA, HIROYUKI KAWANO, AKIHIKO KAWAHARA, RYUTA TAKASE, UHI TOH, KAZUAKI HASHIMOTO, TORU HISAKA, SHINGO HIRAI, MASAHIRO MITSUOKA, DAIKI MIYAZAKI, FUMI YOSHITOMI, KEN YAMAMOTO, HIROHITO UMENO, MASAHISA NOMURA and YOSHIKI NAITO
Anticancer Research August 2025, 45 (8) 3479-3486; DOI: https://doi.org/10.21873/anticanres.17709

Characterization of Tumor Immune Microenvironment in Meningiomas: Correlation of Tumor-infiltrating Lymphocyte Aggregates With Tumor Grade
TOSHIAKI INOMO, MASASUKE OHNO, TORU NAGASAKA, SHUNICHIRO KURAMITSU, EIJI ITO, TADASHI WATANABE and MITSUGU FUJITA
Anticancer Research August 2025, 45 (8) 3487-3496; DOI: https://doi.org/10.21873/anticanres.17710

Standardized Technique for Minimally Invasive Right Posterior Sectionectomy for Hepatocellular Carcinoma: A Propensity Score-matched Study
HISAMUNE SAKAI, YUICHI GOTO, SHOGO FUKUTOMI, SHOICHIROU ARAI, RYUTA MIDORIKAWA, KAZUAKI HASHIMOTO, DAIKI MIYAZAKI, MASANORI AKASHI, NOBUYA ISHIBASHI, KOJI OKUDA, FUMIHIKO FUJITA and TORU HISAKA
Anticancer Research August 2025, 45 (8) 3497-3510; DOI: https://doi.org/10.21873/anticanres.17711

CD155 Expression Predicts Poor Prognosis in OTSCC and Correlates With TIGIT Expression and Tumor Budding
SHOICHI KIMURA, MIKIKO AOKI, KENSUKE NISHI, TORANOSHIN TAKEUCHI, TAKAFUMI YAMANO, TOSHIFUMI SAKATA, TOSHIYUKI TSUNODA and MAKOTO HAMASAKI
Anticancer Research August 2025, 45 (8) 3511-3522; DOI: https://doi.org/10.21873/anticanres.17712

Short- and Long-term Outcomes of Laparoscopic Versus Open Repeat Hepatectomy for Hepatocellular Carcinoma
SHOGO FUKUTOMI, HISAMUNE SAKAI, YUICHI GOTO, KAZUAKI HASHIMOTO, RYUTA MIDORIKAWA, SHOICHIRO ARAI, MASANORI AKASHI, TARO ISOBE, TAKEHUMI YOSHIDA, NAOKI MORI, NOBUYA ISHIBASHI, FUMIHIKO FUJITA and TORU HISAKA
Anticancer Research August 2025, 45 (8) 3523-3530; DOI: https://doi.org/10.21873/anticanres.17713

Novel UF-5000-based Detection, Integrating Inflammatory Parameters, for Urothelial Carcinoma of the Urinary Bladder
KAZUHIRO OKADA, YOSHIKI NAITO, SAORI IRIE, CHIKA NAKAMOTO, KENJI KUBOYAMA, TOSHIKI TARUMIZU, MISAKI IKEDA, YUKO TAKUMA, RYO MAKINO, AKIHIKO KAWAHARA and HIROYUKI KAWANO
Anticancer Research August 2025, 45 (8) 3531-3541; DOI: https://doi.org/10.21873/anticanres.17714

Development and External Validation of Machine Learning-based Models for Predicting Survival Outcomes in Endometrial Cancer: A Population-based Study
MUNETOSHI AKAZAWA, KAZUNORI HASHIMOTO and HIROAKI NAGANO
Anticancer Research August 2025, 45 (8) 3543-3551; DOI: https://doi.org/10.21873/anticanres.17715

Clinical Evaluation of Immune Cell Therapy in Esophageal Cancer Resistant to Immunochemotherapy
RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, HIROSHI IBE, ERI OGUMA, AYA OHNO and SHIGENORI GOTO
Anticancer Research August 2025, 45 (8) 3553-3559; DOI: https://doi.org/10.21873/anticanres.17716

Late-onset Colonic Graft and Overlying Skin Necrosis 15 Years After Esophagectomy and Gastrectomy: A Case Report
KOKI FUJIWARA, JUNKO MUKOHYAMA, FUMIHIKO KATO, AYU KATO, SOJUN HOSHIMOTO, MASAHIRO SHINODA, YOSHIFUMI IKEDA and OSAMU ITANO
Anticancer Research August 2025, 45 (8) 3561-3566; DOI: https://doi.org/10.21873/anticanres.17717

Endometrial Cancer Metastatic to the Sigmoid Colon and Pelvic Retroperitoneal Space: A Case Report
JUNKO MUKOHYAMA, ITARU SAITO, SATOSHI MOCHIZUKI, YASUNORI OTA, GO ITO, JUN IMAIZUMI, SATOKO MONMA, NAOKI SAKUYAMA, SUSUMU AIKOU and DAI SHIDA
Anticancer Research August 2025, 45 (8) 3567-3573; DOI: https://doi.org/10.21873/anticanres.17718

PROCEEDINGS OF WORKSHOP IN THE 28TH ANNUAL MEETING OF THE JAPANESE ASSOCIATION FOR BIOTHERAPEUTICS

Preface
Toshiyuki Tsunoda and Toyofumi Hirakawa
Anticancer Research August 2025, 45 (8) 3575; DOI: https://doi.org/10.21873/anticanres.17719

Application of Nucleic Acid Medicine Using Autologous Serum-derived Small Extracellular Vesicles for Cancer Metastasis
MAI HAZEKAWA, TAKUYA NISHINAKAGAWA and DAISUKE ISHIBASHI
Anticancer Research August 2025, 45 (8) 3577-3586; DOI: https://doi.org/10.21873/anticanres.17720

microRNA in Chorioamnionitis: Emerging Biomarkers for Early Diagnosis
CHIHIRO KIYOSHIMA, DAICHI URUSHIYAMA, KENICHI YOSHIKAWA, KOKO ISHIDA and FUSANORI YOTSUMOTO
Anticancer Research August 2025, 45 (8) 3587-3594; DOI: https://doi.org/10.21873/anticanres.17721

　Contents

Knockdown of CDX2 Induces microRNA-221 Up-regulation in Human Colon Cancer Cells
JUNKO MUKOHYAMA, MINORI KOIZUMI, KIMIHIRO YAMASHITA, AKIHIDE YOSHIMI, DAI SHIDA and YOSHIHIRO KAKEJI
Anticancer Research August 2024, 44 (8) 3553-3556; DOI: https://doi.org/10.21873/anticanres.17177

Inhibitory Effect of Pyra–Metho–Carnil on the Differentiation and Maturation of Macrophages in Normal and Cancer Microenvironments
TAKANORI KITAGUCHI, TAICHI MATSUMOTO, KAZUMASA YOSHIDA, YURIKO HAMAGUCHI, GEN MARUTA, HISANORI MAEOKA, SHUHEI ISHIKURA, MICHITAKA NAKANO, YUSUKE ISHIDA, FUMIHITO HIRAI, MIKIKO AOKI, SHOHTA KODAMA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA
Anticancer Research August 2024, 44 (8) 3557-3565; DOI: https://doi.org/10.21873/anticanres.17178

Identification of DNA Repair-related Genes as Biomarkers Reflecting MSI, TMB, and TIL in Colorectal Cancer
JUNYA FUKUDA, TOMOYA SUDO, MAAKO KIKUCHI, AKIHIKO KAWAHARA, HIRONA SHIGYO, YUSUKE KAWAMOTO, SATOSHI SHIMAMURA, FUMIKI KOGA, TAKASI NOGUCHI, HIROYUKI NAKANE, TAKAHIRO SHIGAKI, KENJI FUJIYOSHI, TAKATO YOMODA, NAOHIRO YOSHIDA, KENICHI KOUSHI, TAKEFUMI YOSHIDA, JUN AKIBA and FUMIHIKO FUJITA
Anticancer Research August 2024, 44 (8) 3567-3575; DOI: https://doi.org/10.21873/anticanres.17179

Adipose-derived Mesenchymal Stem Cell Transplantation Improves Ovarian Function and Oocyte Quality in Aged Mice
TOYOFUMI HIRAKAWA, FUSANORI YOTSUMOTO, SHIORI IMI, NORIKO ITO, KEISUKE ISHIWATA, KAZUHIKO NAKABAYASHI, ASAKO WATANABE, NAOTO SHIRASU, DAICHI URUSHIYAMA, KOHEI MIYATA, SHINYA TAKAHASHI, TSUKASA BABA, KENICHIRO HATA, SHIN’ICHIRO YASUNAGA and SHINGO MIYAMOTO
Anticancer Research August 2024, 44 (8) 3577-3586; DOI: https://doi.org/10.21873/anticanres.17180

Interactive Analysis of UTX-114 Family With EGFR-tyk: Molecular Features of Acetyl Glycosylated Gefitinib
KAZUTO OHKURA, ATSUSHI TABATA and YOSHIHIRO UTO
Anticancer Research August 2024, 44 (8) 3587-3591; DOI: https://doi.org/10.21873/anticanres.17181

Tranilast Inhibits TRPV2 and Suppresses Fibrosis Progression and Weight Gain in a NASH Model Mouse
TAKAHIRO NAGATA, SATOSHI SHAKADO, ERI YAMAUCHI, HIROAKI TOKUSHIGE, TAKASHI MIYAYAMA, RYO YAMAUCHI, HIROMI FUKUDA, ATSUSHI FUKUNAGA, TAKASHI TANAKA, KAZUHIDE TAKATA, KEIJI YOKOYAMA and FUMIHITO HIRAI
Anticancer Research August 2024, 44 (8) 3593-3604; DOI: https://doi.org/10.21873/anticanres.17182

Effect of Ganoderma lucidum on Cisplatin-induced Nephrotoxicity and Gastrointestinal Toxicity
NATSUKI OTA, SHOYA ENDO, RYOSUKE TATSUNAMI, AOI YAMAGUCHI, KOJI WAKAME, AKIFUMI NAKATA and KEISUKE SATO
Anticancer Research August 2024, 44 (8) 3605-3613; DOI: https://doi.org/10.21873/anticanres.17183

Tertiary Lymphoid Structures in Brain Metastases of Lung Cancer: Prognostic Significance and Correlation With Clinical Outcomes
SHOTA NOHIRA, SHUNICHIRO KURAMITSU, MASASUKE OHNO, MITSUGU FUJITA, KIMIHIRO YAMASHITA, TORU NAGASAKA, SHOICHI HAIMOTO, NORIAKI SAKAKURA, HIROKAZU MATSUSHITA and RYUTA SAITO
Anticancer Research August 2024, 44 (8) 3615-3621; DOI: https://doi.org/10.21873/anticanres.17184

Clinicopathological Study of Resected and Recurrent Cases of Intrahepatic Intraductal Papillary Neoplasm of the Bile Duct
SHOICHIRO ARAI, HISAMUNE SAKAI, MASANORI AKASHI, YUICHI GOTO, DAIKI MIYAZAKI, KAZUAKI HASHIMOTO, RYUTA MIDORIKAWA, SHOGO FUKUTOMI, TAKEFUMI YOSHIDA, TARO ISOBE, NAOKI MORI, NOBUYA ISHIBASHI, YOSHIKI NAITO, JUN AKIBA, FUMIHIKO FUJITA and TORU HISAKA
Anticancer Research August 2024, 44 (8) 3623-3628; DOI: https://doi.org/10.21873/anticanres.17185

A Multidisciplinary Therapeutic Approach Proposal for Huge Hepatocellular Carcinomas Exceeding 10 cm in Diameter
YUICHI GOTO, TAKASHI NIIZEKI, HISAMUNE SAKAI, MASANORI AKASHI, SHOGO FUKUTOMI, KAZUAKI HASHIMOTO, HIDEKI IWAMOTO, SHIGEO SHIMOSE, TOMOTAKE SHIRONO, TAKEFUMI YOSHIDA, TARO ISOBE, NAOKI MORI, TAKUMI KAWAGUCHI, NOBUYA ISHIBASHI, FUMIHIKO FUJITA and TORU HISAKA
Anticancer Research August 2024, 44 (8) 3629-3636; DOI: https://doi.org/10.21873/anticanres.17186

Stromal CD73 Expression in Breast Cancer: Subtype-specific Expression and its Prognostic Significance
MASUMI TANAKA, MIKIKO AOKI, YOSHIKO MASUDA, YASUTERU YOSHINAGA, MAKOTO HAMASAKI, AKINORI IWASAKI and TOSHIHIKO SATO
Anticancer Research August 2024, 44 (8) 3637-3643; DOI: https://doi.org/10.21873/anticanres.17187

Safety and Feasibility of Laparoscopic Anatomical Liver Resection for Hepatocellular Carcinoma: A Propensity Score-matched Study
HISAMUNE SAKAI, YUICHI GOTO, SHOGO FUKUTOMI, SHOICHIROU ARAI, RYUTA MIDORIKAWA, KAZUAKI HASHIMOTO, DAIKI MIYAZAKI, MASANORI AKASHI, NOBUYA ISHIBASHI, KOJI OKUDA, FUMIHIKO FUJITA and TORU HISAKA
Anticancer Research August 2024, 44 (8) 3645-3653; DOI: https://doi.org/10.21873/anticanres.17188

Efficacy of Reinforced Stapler for Preventing Postoperative Pancreatic Fistula After Minimally Invasive Distal Pancreatectomy
TOMOKI RYU, YORIKO NOMURA, KAZUKI TAKEISHI, GEN YAMAMOTO, YOSHIYUKI WADA and YUKO TAKAMI
Anticancer Research August 2024, 44 (8) 3655-3661; DOI: https://doi.org/10.21873/anticanres.17189

Survival Impact of Postoperative Whole-brain Radiotherapy and Systemic Chemotherapy After Surgical Resection of Brain Metastases
HIROMASA YOSHIOKA, TAKESHI OKUDA, MITSUGU FUJITA, TAKAYUKI NAKAO and JUN C. TAKAHASHI
Anticancer Research August 2024, 44 (8) 3663-3667; DOI: https://doi.org/10.21873/anticanres.17190

Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score As a Predictor of Prognosis After Hepatectomy
KAZUAKI HASHIMOTO, HIROKI KANNO, HISAMUNE SAKAI, DAIKI MIYAZAKI, SHOGO FUKUTOMI, SHOICHIRO ARAI, YUICHI GOTO, MASANORI AKASHI, TARO ISOBE, NAOKI MORI, NOBUYA ISHIBASHI, FUMIHIKO FUJITA and TORU HISAKA
Anticancer Research August 2024, 44 (8) 3669-3678; DOI: https://doi.org/10.21873/anticanres.17191

　Contents

Inhibitory Effect of Pyra–Metho–Carnil on Cancer Spheroid Growth Through Decrease in Glycolysis-associated Molecules
KAZUMASA YOSHIDA, KENSUKE NISHI, SHUHEI ISHIKURA, TAICHI MATSUMOTO, KAZUHIKO NAKABAYASHI, RYO YAZAKI, TAKASHI OHSHIMA, MASAHIKO SUENAGA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA
Anticancer Research August 2023, 43 (8) 3717-3726; DOI: https://doi.org/10.21873/anticanres.16556

Significance of Desmoplastic Histopathological Growth Pattern for Colorectal Liver Metastases Treated With Preoperative Chemotherapy
HIROAKI HIRAKAWA, HISAMUNE SAKAI, HIROKI KANNO, YUICHI GOTO, MASANORI AKASHI, SHOGO FUKUTOMI, SHOICHIRO ARAI, TOSHIHIRO SATO, TOMOYA SUDO, SACHIKO NAGASU, KEISUKE MIWA, YOSHIKI NAITO, JUN AKIBA, HIROHISA YANO, FUMIHIKO FUJITA and TORU HISAKA
Anticancer Research August 2023, 43 (8) 3727-3733; DOI: https://doi.org/10.21873/anticanres.16557

MMP-2 Regulation of Emmprin on Tumour Cells and CD73 on Fibroblasts During Tumour-Stromal Interaction
MIKIKO AOKI, TOSHIYUKI TSUNODA, KAORI KOGA, KAZUKI NABESHIMA and MAKOTO HAMASAKI
Anticancer Research August 2023, 43 (8) 3735-3745; DOI: https://doi.org/10.21873/anticanres.16558

Molecular Aspects of C-glycosides: Interactive Analysis of C-linked Compounds With the SGLT2 Molecular Model
KAZUTO OHKURA and ATSUSHI TABATA
Anticancer Research August 2023, 43 (8) 3747-3754; DOI: https://doi.org/10.21873/anticanres.16559

Deep Learning-based Image Cytometry Using a Bit-pattern Kernel-filtering Algorithm to Avoid Multi-counted Cell Determination
TOMOKI ABE, KIMIHIRO YAMASHITA, TORU NAGASAKA, MITSUGU FUJITA, KYOUSUKE AGAWA, MASAYUKI ANDO, TOMOSUKE MUKOYAMA, KOTA YAMADA, SOUICHIRO MIYAKE, MASAFUMI SAITO, RYUICHIRO SAWADA, HIROSHI HASEGAWA, TAKERU MATSUDA, TAKASHI KATO, HITOSHI HARADA, NAOKI URAKAWA, HIRONOBU GOTO, SHINGO KANAJI, HIROAKI YANAGIMOTO, TARO OSHIKIRI, TETSUO AJIKI, TAKUMI FUKUMOTO and YOSHIHIRO KAKEJI
Anticancer Research August 2023, 43 (8) 3755-3761; DOI: https://doi.org/10.21873/anticanres.16560

CDX2 Is a Prognostic Biomarker for Unresectable Metastatic Colorectal Cancer
JUNKO MUKOHYAMA, KYOSUKE AGAWA, KIMIHIRO YAMASHITA, TAKERU MATSUDA, MASAHIRO SHINODA, OSAMU ITANO and YOSHIHIRO KAKEJI
Anticancer Research August 2023, 43 (8) 3763-3767; DOI: https://doi.org/10.21873/anticanres.16561

Antitumor Effect of Galectin-9 on Cell Proliferation and Tumor Growth of Human Duodenal Adenocarcinoma Cells
TOSHIAKI KONO, SHINTARO FUJIHARA, KYOKO OURA, HISAKAZU IWAMA, KOJI FUJITA, NAOKI FUJITA, KEI TAKUMA, MASAHIRO ONO, DAISUKE NAMIMA, HIROKI YAMANA, TAIGA CHIYO, KIYOYUKI KOBAYASHI, HIDEKI KAMADA, HIDEKI KOBARA, MASAHUMI ONO, TOSHIRO NIKI, MITSUOMI HIRASHIMA and TSUTOMU MASAKI
Anticancer Research August 2023, 43 (8) 3769-3777; DOI: https://doi.org/10.21873/anticanres.16562

Impact of Skeletal Muscle Mass Reduction on Long-term Survival After Radical Resection of Gastric Cancer
YUYA TANAKA, KEISHIRO AOYAGI, YUKI UMETANI, YU TANAKA, HIDEAKI KAKU, TAIZAN MINAMI, TARO ISOBE, NAOTAKA MURAKAMI, FUMIHIKO FUJITA and YOSHITO AKAGI
Anticancer Research August 2023, 43 (8) 3779-3786; DOI: https://doi.org/10.21873/anticanres.16563

Association of UBE2L6 and ABCB6 Expression With Platinum Resistance in Serous Ovarian Carcinoma
MAMI SHIBAHARA, TOMOKO KURITA, MIDORI MURAKAMI, HIROSHI HARADA, CHIHO KOI, HIROTO IZUMI and KIYOSHI YOSHINO
Anticancer Research August 2023, 43 (8) 3787-3792; DOI: https://doi.org/10.21873/anticanres.16564

Simplified and Optimized Immune Score for Colorectal Cancer Microenvironment
HIROYUKI NAKANE, TOMOYA SUDO, AKIHIRO KAWAHARA, TAKATOU YOMODA, TAKAHIRO SHIGAKI, KENJI FUJIYOSHI, TAKAFUMI OHCHI, KENICHI KOUSHI, TAKEFUMI YOSHIDA, TOSHIRO OGATA, FUMIHIKO FUJITA and YOSHITO AKAGI
Anticancer Research August 2023, 43 (8) 3793-3798; DOI: https://doi.org/10.21873/anticanres.16565

Positive Ascites Cytology, Postoperative Chemotherapy and Prognosis of Stage I Ovarian Clear Cell Carcinoma
MICHIKO KUBO-KANEDA, EIJI KONDO, TOSHIHARU OKUGAWA, TAKAHARU YAMAWAKI, TORU HIRATA, MAKOTO TSUJI, KENJI NAGAO, MAYA KATO, KOICHI YOSHIMURA and TOMOAKI IKEDA
Anticancer Research August 2023, 43 (8) 3799-3805; DOI: https://doi.org/10.21873/anticanres.16566

Development of an Algorithm to Predict Recurrences After Resection of Liver Metastases in Patients With Metastatic Colorectal Cancer
MITSUHIRO KATAGIRI, TOMOYA SUDO, TATSUYUKI TOUNANN, TATSUYUKI KAKUMA, SUSUMU SHIMOMURA, SACHIKO NAGASU, KENSUKE TAJIRI, SHINYA FUJINO, KOUTAROU YUGE, HIDETSUGU MURAKAMI, KEISUKE MIWA, TORU HISAKA, FUMIHIKO FUJITA and YOSHITO AKAGI
Anticancer Research August 2023, 43 (8) 3807-3816; DOI: https://doi.org/10.21873/anticanres.16567

Preliminary Results of Deep Learning Approach for Preoperative Diagnosis of Ovarian Cancer Based on Pelvic MRI Scans
MUNETOSHI AKAZAWA and KAZUNORI HASHIMOTO
Anticancer Research August 2023, 43 (8) 3817-3821; DOI: https://doi.org/10.21873/anticanres.16568

　Contents

Anti-inflammatory and Insulin Signaling Phenotype Induced by Repeated Lipopolysaccharide Stimulation in 3T3-L1 Adipocytes
KAZUSHI YAMAMOTO, MASASHI YAMASHITA, HIROYUKI INAGAWA, CHIE KOHCHI and GEN-ICHIRO SOMA
Anticancer Research August 2022, 42 (8) 3983-3991; DOI: https://doi.org/10.21873/anticanres.15894

Cancer Spheroid Proliferation Is Suppressed by a Novel Low-toxicity Compound, Pyra-Metho-Carnil, in a Context-independent Manner
KAZUMASA YOSHIDA, KENSUKE NISHI, SHUHEI ISHIKURA, KAZUHIKO NAKABAYASHI, RYO YAZAKI, TAKASHI OHSHIMA, MASAHIKO SUENAGA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA
Anticancer Research August 2022, 42 (8) 3993-4001; DOI: https://doi.org/10.21873/anticanres.15895

Significance of Intraperitoneal-free KRT20 and CEACAM6 mRNA Expression for Peritoneal Recurrence of Gastric Cancer
HIDEAKI KAKU, KEISHIRO AOYAGI, TOMOYA SUDO, YUYA TANAKA, TAIZAN MINAMI, TARO ISOBE, JUNYA KIZAKI, YUKI UMETANI, NAOTAKA MURAKAMI, FUMIHIKO FUJITA and YOSHITO AKAGI
Anticancer Research August 2022, 42 (8) 4003-4010; DOI: https://doi.org/10.21873/anticanres.15896

Experimental Exploration for Genes Related to Susceptibility and Resistance to Irinotecan
SUGURU OGATA, TOMOYA SUDOU, FUMIHIKO FUJITA, TAKEFUMI YOSHIDA, KENICHI KOUSHI, TAKASHI NOGUCHI, JUNYA FUKUDA, NANAE OGATA, YOSHITAKA NOBUKUNI and YOSHITO AKAGI
Anticancer Research August 2022, 42 (8) 4011-4016; DOI: https://doi.org/10.21873/anticanres.15897

Molecular Interaction Between Boron Tracedrug UTX-51 Derivatives and Bovine Serum Albumin: Application to an Analytical Model of AGEs Destruction by Thermal Neutron Irradiation
KAZUTO OHKURA, ATSUSHI TABATA, YOSHIHIRO UTO and HITOSHI HORI
Anticancer Research August 2022, 42 (8) 4017-4023; DOI: https://doi.org/10.21873/anticanres.15898

Effect of Chloroquine on Doxorubicin-induced Apoptosis in A549 Cells
KEISUKE SATO, NATSUKI OTA, SHOYA ENDO, AKIFUMI NAKATA, HIROSHI YAMASHITA and RYOSUKE TATSUNAMI
Anticancer Research August 2022, 42 (8) 4025-4035; DOI: https://doi.org/10.21873/anticanres.15899

Effect of Aspirin on G0/G1 Cell Cycle Arrest and microRNA Signatures in Pancreatic Adenocarcinoma Cells
RYOTA NAKABAYASHI, SHINTARO FUJIHARA, HISAKAZU IWAMA, SAE HAMAYA, TAKAAKI MIZUO, MASAHIRO HIRATA, KOJI FUJITA, TOSHIAKI KONO, DAISUKE NAMIMA, NAOKI FUJITA, HIROKI YAMANA, KIYOYUKI KOBAYASHI, HIDEKI KAMADA, ASAHIRO MORISHITA, HIDEKI KOBARA, MASAFUMI ONO, KEIICHI OKANO and TSUTOMU MASAKI
Anticancer Research August 2022, 42 (8) 4037-4048; DOI: https://doi.org/10.21873/anticanres.15900

Suppression of Inflammatory Cytokine Genes Expression in Vascular Endothelial Cells by Super-low Dose Lipopolysaccharide-activated Macrophages
TERUKO HONDA and HIROYUKI INAGAWA
Anticancer Research August 2022, 42 (8) 4049-4054; DOI: https://doi.org/10.21873/anticanres.15901

Oral Administration of Mulberry (Morus alba L.) Leaf Powder Prevents the Development of Hepatocellular Carcinoma in Stelic Animal Model (STAM) Mice
KOJI WAKAME, KEISUKE SATO, MASAFUMI KASAI, EMI KIKUCHI, KIHIRO SHIMIZU, AKO KUDO, KEN-ICHI KOMATSU and AKIFUMI NAKATA
Anticancer Research August 2022, 42 (8) 4055-4062; DOI: https://doi.org/10.21873/anticanres.15902

Salvage PTBD With Chemotherapy Improves Survival in Patients With Unresectable Malignant Biliary Obstruction – A Single Center Retrospective Study
DAISUKE MUROYA, HIROTOSHI TSURU, HISAAKI SHIMOKOBE, YUICHI NAGAO, YASUNORI YOSHIMOTO, YOSHITO WADA, KOUJI HAYASHI, SATOSHI TANIWAKI, RYUTA MIDORIKAWA, SHINICHI TANIWAKI, SATOKI KOJIMA, SHOICHIRO ARAI, TAKAHISA SHIRAHAMA, YUICHI GOTO, HISAMUNE SAKAI, MUNEHIRO YOSHITOMI, TORU HISAKA, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2022, 42 (8) 4063-4070; DOI: https://doi.org/10.21873/anticanres.15903

CCND1 Copy Number Variation in Circulating Tumor DNA from Luminal B Breast Cancer Patients
AKIKO SHIMAZAKI, MAKOTO KUBO, KANAKO KURATA, YUKA TAKAO, SAORI HAYASHI, YURINA HARADA, HITOMI KAWAJI, KAZUHISA KANESHIRO, MAI YAMADA, MASAYA KAI and MASAFUMI NAKAMURA
Anticancer Research August 2022, 42 (8) 4071-4077; DOI: https://doi.org/10.21873/anticanres.15904

Tumour Budding as an Independent Prognostic Factor for Survival in Patients With Distal Bile Duct Cancer
GOICHI NAKAYAMA, TORU HISAKA, HISAMUNE SAKAI, MASANORI AKASHI, GOTO YUICHI, TOSHIHIRO SATO, YOSHIKI NAITO, JUN AKIBA, HIROHISA YANO and YOSHITO AKAGI
Anticancer Research August 2022, 42 (8) 4079-4087; DOI: https://doi.org/10.21873/anticanres.15905

Liberal Application of Portal Vein Embolization for Right Hepatectomy Against Hepatocellular Carcinoma: Strategy to Achieve Zero Mortality for a Damaged Liver
NOBUHISA SHIRAHAMA, YUICHI GOTO, HISAMUNE SAKAI, SHOGO FUKUTOMI, MASANORI AKASHI, TOSHIHIRO SATO, YOSHITO AKAGI, KOJI OKUDA and TORU HISAKA
Anticancer Research August 2022, 42 (8) 4089-4095; DOI: https://doi.org/10.21873/anticanres.15906

Significance of the Multi-gene Panel myRisk in Japan
SAORI HAYASHI, MAKOTO KUBO, SAWAKO MATSUZAKI, MASAYA KAI, TAKAFUMI MORISAKI, MAI YAMADA, KAZUHISA KANESHIRO, YUKA TAKAO, AKIKO SHIMAZAKI, KINUKO NAGAYOSHI, YUSUKE MIZUUCHI and MASAFUMI NAKAMURA
Anticancer Research August 2022, 42 (8) 4097-4102; DOI: https://doi.org/10.21873/anticanres.15907

Standardized Methods Using EUS-guided Fine-needle Biopsy and a Minimal Medium Creates Three Pancreatic Cancer Organoids
YUSUKE ISHIDA, TOSHIYUKI TSUNODA, YOSHIHIRO HAMADA, NAOAKI TSUCHIYA, TAKEHIKO KOGA, TAKANORI KITAGUCHI, KEISUKE MATSUMOTO, SHINJI MATSUMOTO, TAKAHIDE SASAKI, RYO NAKASHIMA, FUMINORI ISHII, MASATOSHI KAJIWARA, SENJI SHIRASAWA, SUGURU HASEGAWA and FUMIHITO HIRAI
Anticancer Research August 2022, 42 (8) 4103-4109; DOI: https://doi.org/10.21873/anticanres.15908

Cumulative Summation Analysis of Learning Curve for Robotic-assisted Hysterectomy in Patients With Gynecologic Tumors
FUSANORI YOTSUMOTO, AYAKO SANUI, TOMOHIRO ITO, DAISUKE MIYAHARA, KENICHI YOSHIKAWA, KOICHIRO SHIGEKAWA, YUKIKO NOGUCHI, SHIN’ICHIRO YASUNAGA and SHINGO MIYAMOTO
Anticancer Research August 2022, 42 (8) 4111-4117; DOI: https://doi.org/10.21873/anticanres.15909

Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell Adhesion Molecule 6, and Ectopic Claudin-2 in the Carcinogenic Processes of Ulcerative Colitis
TETSUSHI KINUGASA, TOSHIYUKI TSUNODA, EMIKO MIZOGUCHI, TOSHIYUKI OKADA, TOMOYA SUDO, AKIHIKO KAWAHARA, JUN AKIBA and YOSHITO AKAGI
Anticancer Research August 2022, 42 (8) 4119-4127; DOI: https://doi.org/10.21873/anticanres.15910

Hematogenous Dissemination of Tumor Cells in Hepatocellular Carcinoma: Comparing Anterior and Non-anterior Approach Hepatectomy
SHIN SASAKI, YORIKO NOMURA, TOMOYA SUDO, HISAMUNE SAKAI, TORU HISAKA, JUN AKIBA, OSAMU NAKASHIMA, HIROHISA YANO, MASAYOSHI KAGE, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2022, 42 (8) 4129-4137; DOI: https://doi.org/10.21873/anticanres.15911

Efficacy and Safety of Monthly Minodronate Therapy in Postmenopausal Breast Cancer Patients Receiving Aromatase Inhibitors
NANAE OGATA, UHI TOH, TOMOYA SUDOU, SUGURU OGATA, YUKO TAKAO, RIE SUGIHARA, HIDEAKI WATANABE, SHUNTARO MATUSHIMA and YOSHITO AKAGI
Anticancer Research August 2022, 42 (8) 4139-4143; DOI: https://doi.org/10.21873/anticanres.15912

Predictive and Prognostic Value of SUOX Expression in Pancreatic Ductal Adenocarcinoma
YOSHIKI NAITO, JUN AKIBA, YOSHINAO KINJO, EIJI SADASHIMA, TOSHIRO OGATA, YUTA YANO, MASAHIKO TANIGAWA, MASAMICHI NAKAYAMA, AKIHIKO KAWAHARA, YOSHINOBU OKABE, HISAMUNE SAKAI, TORU HISAKA, YOSHITO AKAGI and HIROHISA YANO
Anticancer Research August 2022, 42 (8) 4145-4151; DOI: https://doi.org/10.21873/anticanres.15913

Pancreaticoenterostomy With Seromuscular-parenchymal Anastomosis for Prevention of Postoperative Pancreatic Fistula in Distal Pancreatectomy
SATOSHI TANIWAKI, DAISUKE MUROYA, YOSHITO WADA, KOUJI OKUDA, HIROTOSHI TSURU, HISAAKI SHIMOKOUBE, YUICH NAGAO, KOUJI HAYASHI and YUKI YOSHIMOTO
Anticancer Research August 2022, 42 (8) 4153-4157; DOI: https://doi.org/10.21873/anticanres.15914

Fatty Liver Does Not Increase the Risk of Postoperative Liver Damage Following Hepatectomy
YORIKO NOMURA, JUN AKIBA, HIROHISA YANO, YOSHITO AKAGI and TORU HISAKA
Anticancer Research August 2022, 42 (8) 4159-4164; DOI: https://doi.org/10.21873/anticanres.15915

Adverse Events Associated With Long-term Treatment of Epithelial Ovarian Cancer With Bevacizumab and Chemotherapy
YUKA YOKOYAMA, MICHIKO KUBO-KANEDA, KIMI SUNADA, YASUHIRO TEISHIKATA, ASA KITAMURA, KOTA OKAMOTO, KUNIAKI TORIYABE, MASAFUMI NII, KENTA YOSHIDA, EIJI KONDO and TOMOAKI IKEDA
Anticancer Research August 2022, 42 (8) 4165-4171; DOI: https://doi.org/10.21873/anticanres.15916

Experience With Tirabrutinib in the Treatment of Primary Central Nervous System Lymphoma that Is Difficult to Treat With Standard Treatment
HIROMASA YOSHIOKA, TAKESHI OKUDA, TAKAYUKI NAKAO, MITSUGU FUJITA and JUN C. TAKAHASHI
Anticancer Research August 2022, 42 (8) 4173-4178; DOI: https://doi.org/10.21873/anticanres.15917

Efficacy of Adjuvant Immune-cell Therapy Combined With Systemic Therapy for Solid Tumors
RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, HIROSHI IBE, ERI OGUMA and SHIGENORI GOTO
Anticancer Research August 2022, 42 (8) 4179-4187; DOI: https://doi.org/10.21873/anticanres.15918

　Contents

TrkB/BDNF Signaling Could Be a New Therapeutic Target for Pancreatic Cancer
YASUHIRO OYAMA, SHINJIRO NAGAO, LIN NA, KOSUKE YANAI, MASAYO UMEBAYASHI, KATSUYA NAKAMURA, SHUNTARO NAGAI, AKIKO FUJIMURA, AKIO YAMASAKI, KAZUNORI NAKAYAMA, TAKASHI MORISAKI and HIDEYA ONISHI
Anticancer Research August 2021, 41 (8) 4047-4052; DOI: https://doi.org/10.21873/anticanres.15205

Oral Administration of Lipopolysaccharide Prevents Cognitive Impairment in Streptozotocin-induced Diabetic Mice in a Blood Glucose-independent Manner
HARUKA MIZOBUCHI, KAZUSHI YAMAMOTO, MASASHI YAMASHITA, HIROYUKI INAGAWA, CHIE KOHCHI and GEN-ICHIRO SOMA
Anticancer Research August 2021, 41 (8) 4053-4059; DOI: https://doi.org/10.21873/anticanres.15206

Growth Suppression of Cancer Spheroids With Mutated KRAS by Low-toxicity Compounds from Natural Products
SAYURI HASHIMOTO, MASAYOSHI NAGAI, KENSUKE NISHI, SHUHEI ISHIKURA, KAZUHIKO NAKABAYASHI, RYO YAZAKI, TAKASHI OHSHIMA, MASAHIKO SUENAGA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA
Anticancer Research August 2021, 41 (8) 4061-4070; DOI: https://doi.org/10.21873/anticanres.15207

Regulation of Plasminogen Activator Inhibitor-1 in Adipocytes by Macrophages Activated by Low-dose Lipopolysaccharide
TERUKO HONDA and HIROYUKI INAGAWA
Anticancer Research August 2021, 41 (8) 4071-4076; DOI: https://doi.org/10.21873/anticanres.15208

Knockdown of D-dopachrome Tautomerase Inhibits Cell Proliferation in Human HepG2 Cell Line
ASUKA TAKAHASHI, TAKEO IWATA and KIKUJI YAMASHITA
Anticancer Research August 2021, 41 (8) 4077-4082; DOI: https://doi.org/10.21873/anticanres.15209

Construction of a Drug Release Evaluation System: Application of Mitochondrial Respiration to Monitor Drug Release
KAZUTO OHKURA, YOHEI TATEMATSU and ATSUSHI TABATA
Anticancer Research August 2021, 41 (8) 4083-4088; DOI: https://doi.org/10.21873/anticanres.15210

Involvement of Annexin A2 in Serum-MAF Dependent Phagocytic Activation of Macrophages
KUMPEI KAWAKATSU, MISATO MAEMURA, YOSHIKA SETA and TAKAHITO NISHIKATA
Anticancer Research August 2021, 41 (8) 4089-4092; DOI: https://doi.org/10.21873/anticanres.15211

Effects of Kumaizasa (Sasa senanensis) Leaf Extract on Innate Immune Regulation in HEK293 Cells and Macrophages
KEISUKE SATO, RYOSUKE TATSUNAMI, AKIFUMI NAKATA, KEN-ICHI KOMATSU, SHINJI HARAKAWA, TAKAKI NEDACHI, KAORU HAKETA, HIROYUKI INAGAWA and KOJI WAKAME
Anticancer Research August 2021, 41 (8) 4093-4100; DOI: https://doi.org/10.21873/anticanres.15212

Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis
TAKASHI MORISAKI, TAKAFUMI MORISAKI, MAKOTO KUBO, HIDEYA ONISHI, TATSUYA HIRANO, SHINJI MORISAKI, MASATOSHI ETO, KEISUKE MONJI, ARIO TAKEUCHI, SHINICHIRO NAKAGAWA, HIROTO TANAKA, NORIHIRO KOYA, MASAYO UMEBAYASHI, KENTA TSUJIMURA, POH YIN YEW, SACHIKO YOSHIMURA, KAZUMA KIYOTANI and YUSUKE NAKAMURA
Anticancer Research August 2021, 41 (8) 4101-4115; DOI: https://doi.org/10.21873/anticanres.15213

Simple Cancer Stem Cell Markers Predict Neoadjuvant Chemotherapy Resistance of Esophageal Squamous Cell Carcinoma
KYOSUKE AGAWA, KIMIHIRO YAMASHITA, AKIO NAKAGAWA, KOUTA YAMADA, AKIHIRO WATANABE, JUNKO MUKOHYAMA, MASAFUMI SAITO, MITSUGU FUJITA, GOSUKE TAKIGUCHI, NAOKI URAKAWA, HIROSHI HASEGAWA, SHINGO KANAJI, TAKERU MATSUDA, TARO OSHIKIRI, TETSU NAKAMURA, SATOSHI SUZUKI and YOSHIHIRO KAKEJI
Anticancer Research August 2021, 41 (8) 4117-4126; DOI: https://doi.org/10.21873/anticanres.15214

Frailty Status Predicts New Long-term Care Insurance Certification in Hepatitis C Patients Receiving Antiviral Therapy
KENICHI NAKAMURA, KAZUNORI KUSUMOTO, YOSHINORI OZONO, KAZUO KUROKI, YUNOSUKE MATSUURA, TOSHIHIRO MUKUDA, TOSHIMASA OCHIAI, MAI TSUCHIMOCHI, HISAYOSHI IWAKIRI, SATORU HASUIKE, KAZUYA SHIMODA and KENJI NAGATA
Anticancer Research August 2021, 41 (8) 4127-4131; DOI: https://doi.org/10.21873/anticanres.15215

Prognostic Factors for Advanced/Recurrent Breast Cancer Treated With Immune-cell Therapy
RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, HIROSHI IBE, ERI OGUMA and SHIGENORI GOTO
Anticancer Research August 2021, 41 (8) 4133-4141; DOI: https://doi.org/10.21873/anticanres.15216

Effect of the 2013 ASCO-CAP HER2 Testing Guideline on the Management of IHC/HER2 2+ Invasive Breast Cancer
MAI YAMADA, MAKOTO KUBO, HIDETAKA YAMAMOTO, NAMI YAMASHITA, MASAYA KAI, KAREN ZAGUIRRE, KAZUHISA KANESHIRO, AKIKO SHIMAZAKI, SAORI HAYASHI, HITOMI KAWAJI, MASAKI MORI, YOSHINAO ODA and MASAFUMI NAKAMURA
Anticancer Research August 2021, 41 (8) 4143-4149; DOI: https://doi.org/10.21873/anticanres.15217

Effectiveness of Laparoscopic Combined Retroperitoneal and Transperitoneal Approach in Para-aortic Lymphadenectomy for Endometrial Cancer
MICHIKO KUBO-KANEDA, EIJI KONDO, RYO NIMURA, SHINTARO MAKI, MASAFUMI NII, KENTA YOSHIDA and TOMOAKI IKEDA
Anticancer Research August 2021, 41 (8) 4151-4155; DOI: https://doi.org/10.21873/anticanres.15218

Prognostic Benefit of ≥6 Cycles of Neoadjuvant Chemotherapy for Advanced Ovarian, Tubal, and Peritoneal Cancers
EIJI KONDO, RYO NIMURA, SHINTARO MAKI, MICHIKO KANEDA, MASAFUMI NII, KENTA YOSHIDA, TSUTOMU TABATA and TOMOAKI IKEDA
Anticancer Research August 2021, 41 (8) 4157-4161; DOI: https://doi.org/10.21873/anticanres.15219

Laparoscopic Versus Robotic Hysterectomy in Obese Patients With Early-stage Endometrial Cancer: A Single-centre Analysis
KENTA YOSHIDA, EIJI KONDO, RYO NIMURA, SHINTARO MAKI, MICHIKO KANEDA, MASAFUMI NII and TOMOAKI IKEDA
Anticancer Research August 2021, 41 (8) 4163-4167; DOI: https://doi.org/10.21873/anticanres.15220

Effectiveness of Palliative Cerebrospinal Fluid Shunting for Patients With Leptomeningeal Carcinomatosis-related Hydrocephalus
HIROMASA YOSHIOKA, TAKESHI OKUDA, TAKAYUKI NAKAO, MITSUGU FUJITA and JUN C. TAKAHASHI
Anticancer Research August 2021, 41 (8) 4169-4172; DOI: https://doi.org/10.21873/anticanres.15221

Learning Curve of Robotic-assisted Hysterectomy With Pelvic Lymphadenectomy for Early Stage Endometrial Cancer: Analysis of 81 Cases
MUNETOSHI AKAZAWA, KAZUNORI HASHIMOTO, SHENG-LUN LEE and WEI-MIN LIU
Anticancer Research August 2021, 41 (8) 4173-4178; DOI: https://doi.org/10.21873/anticanres.15222

Contents

Current Status of Therapeutic Drug Monitoring of 5-Fluorouracil Prodrugs
YASUHIRO HASHIMOTO, YOICHIRO YOSHIDA, TEPPEI YAMADA, NAOYA AISU, GUMPEI YOSHIMATSU, FUMIHIRO YOSHIMURA and SUGURU HASEGAWA
Anticancer Research August 2020, 40 (8) 4655-4661; DOI: https://doi.org/10.21873/anticanres.14464

Mutant KRAS Promotes NKG2D+ T Cell Infiltration and CD155 Dependent Immune Evasion
KENSUKE NISHI, SHUHEI ISHIKURA, MASAYO UMEBAYASHI, TAKASHI MORISAKI, TAKASHI INOZUME, TETSUSHI KINUGASA, MIKIKO AOKI, SATOSHI NIMURA, ANTHONY SWAIN, YOICHIRO YOSHIDA, SUGURU HASEGAWA, KAZUKI NABESHIMA, TOSHIFUMI SAKATA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA
Anticancer Research August 2020, 40 (8) 4663-4674; DOI: https://doi.org/10.21873/anticanres.14465

Effect of Isomerization of TX-2036 Derivatives on the Interaction With Tyrosine Kinase Domain of EGF Receptor
KAZUTO OHKURA, ATSUSHI TABATA, YOSHIHIRO UTO and HITOSHI HORI
Anticancer Research August 2020, 40 (8) 4675-4680; DOI: https://doi.org/10.21873/anticanres.14466

Enhanced Effect of Hyaluronan and Elastin Synthesis in Fibroblasts Through Lipopolysaccharide-activated Macrophages
TERUKO HONDA, SHOKO TSUTSUI, CHIE KOHCHI and HIROYUKI INAGAWA
Anticancer Research August 2020, 40 (8) 4681-4685; DOI: https://doi.org/10.21873/anticanres.14467

MK615 Suppresses Hypoxia Tolerance by Up-regulation of E-cadherin in Colorectal Cancer Cells With Mutant KRAS
KENSUKE NISHI, TOSHIYUKI TSUNODA, YOSHINORI UCHIDA, TAKAYUKI SUETA, MOTOHIRO SAWATSUBASHI, TAKAFUMI YAMANO, YASUKO HASHIGUCHI, ANTHONY SWAIN, SENJI SHIRASAWA and TOSHIFUMI SAKATA
Anticancer Research August 2020, 40 (8) 4687-4694; DOI: https://doi.org/10.21873/anticanres.14468

Quercetin Suppresses Proliferation of Liver Cancer Cell Lines In Vitro
TORU HISAKA, HISAMUNE SAKAI, TOSHIHIRO SATO, YUICHI GOTO, YORIKO NOMURA, SHOGO FUKUTOMI, FUMIHIKO FUJITA, TOMOAKI MIZOBE, OSAMU NAKASHIMA, MASAHIKO TANIGAWA, YOSHIKI NAITO, JUN AKIBA, SACHIKO OGASAWARA, KOUTA NAKASHIMA, YOSHITO AKAGI, KOJI OKUDA and HIROHISA YANO
Anticancer Research August 2020, 40 (8) 4695-4700; DOI: https://doi.org/10.21873/anticanres.14469

Therapeutic Effect and Mechanism of Action of Low-molecular-weight Whey Protein Capable of Activating Macrophages in Bovine Mastitis
TORU TASAKA, KATSUHIKO MAEHASHI, HISATSUGU YAMADA, AKIHIRO SHIRAI, HIDEKI UNUMA, KEN TOKUNAGA, AKIO HAYAKAWA, AKITERU GO, KIKYO GO and YOSHIHIRO UTO
Anticancer Research August 2020, 40 (8) 4701-4706; DOI: https://doi.org/10.21873/anticanres.14470

Comparison of Macrophage Activation Using γ-Globulin and Serum-derived Macrophage Activating Factor
MINORI AKAMATSU, RIHO MASHIBA, KUMPEI KAWAKATSU, MAMI ISHIKAWA and TAKAHITO NISHIKATA
Anticancer Research August 2020, 40 (8) 4707-4710; DOI: https://doi.org/10.21873/anticanres.14471

Attempt to Construct an In Vitro Model of Enhancement of Macrophage Phagocytosis Via Continuous Administration of LPS
KAZUSHI YAMAMOTO, HARUKA MIZOBUCHI, MASASHI YAMASHITA, HIROYUKI INAGAWA, CHIE KOHCHI and GEN-ICHIRO SOMA
Anticancer Research August 2020, 40 (8) 4711-4717; DOI: https://doi.org/10.21873/anticanres.14472

Mastication Affects Transcriptomes of Mouse Microglia
MINEAKI SEKI, ARISA HAINO, TATSUYA ISHIKAWA, HIROYUKI INAGAWA, GEN-ICHIRO SOMA, HIROSHI TERADA and MASAYUKI NASHIMOTO
Anticancer Research August 2020, 40 (8) 4719-4727; DOI: https://doi.org/10.21873/anticanres.14473

Prognostic Factors for Endometrial and Cervical Cancers of Uterus Treated With Immune-cell Therapy: A Retrospective Study
RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, HIROSHI IBE, ERI OGUMA, KEIKO NAITOH, KAORI MAKITA, KOSEI YASUMOTO and SHIGENORI GOTO
Anticancer Research August 2020, 40 (8) 4729-4740; DOI: https://doi.org/10.21873/anticanres.14474

Adoptive Immune-Cell Therapy for the Treatment of Neuroendocrine Carcinoma of the Uterine Cervix
SHIGENORI GOTO, YASUHISA TERAO, TAKASHI KAMIGAKI, RISHU TAKIMOTO, KEIKO NAITOH, KAORI MAKITA, KOSEI YASUMOTO, SACHIKO OKADA, KEN TAKIZAWA, NORIYUKI YOKOMICHI, NAO SUZUKI and SATORU TAKEDA
Anticancer Research August 2020, 40 (8) 4741-4748; DOI: https://doi.org/10.21873/anticanres.14475

Prognostic Impact of Desmoplastic Reaction Evaluation for Intrahepatic Cholangiocarcinoma
SATOKI KOJIMA, TORU HISAKA, RYUTA MIDORIKAWA, YOSHIKI NAITO, JUN AKIBA, MASAHIKO TANIGAWA, HIROHISA YANO, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2020, 40 (8) 4749-4754; DOI: https://doi.org/10.21873/anticanres.14476

Useful Cases of Patients With Developmental Disorders Improved by Oral Administration of LPS Derived from Pantoea agglomerans
ATSUTOMO MORISHIMA, RAN ZHANG, TAKEMA NAGAOKA and HIROYUKI INAGAWA
Anticancer Research August 2020, 40 (8) 4755-4762; DOI: https://doi.org/10.21873/anticanres.14477

Changes in Immunological Status in Patients With Metastatic Colorectal Cancer Treated With First-line Chemoimmunotherapy
TEPPEI YAMADA, YOICHIRO YOSHIDA, TOSHIKI MAEDA, GUMPEI YOSHIMATSU, NAOYA AISU, KANEFUMI YAMASHITA, AKIRA KOMONO, RYUJI KAJITANI, YOSHIKO MATSUMOTO, HIDEKI NAGANO, KEIKO NAITO, KOSEI YASUMOTO, RISHU TAKIMOTO, TAKASHI KAMIGAKI, SHIGENORI GOTO, FUMIHIRO YOSHIMURA, NAOAKI SAKATA, SHOHTA KODAMA and SUGURU HASEGAWA
Anticancer Research August 2020, 40 (8) 4763-4771; DOI: https://doi.org/10.21873/anticanres.14478

Salvage Surgery for Initially Unresectable Locally Advanced Hepatocellular Carcinoma Downstaged by Hepatic Arterial Infusion Chemotherapy
YUICHI GOTO, TORU HISAKA, HISAMUNE SAKAI, KATSUAKI TAKAGI, SHOGO FUKUTOMI, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2020, 40 (8) 4773-4777; DOI: https://doi.org/10.21873/anticanres.14479

Pilot Study of Irinotecan and S-1 (IRIS) for Advanced and Metastatic Breast Cancer
TOSHIHIRO TANAKA, MAKI TANAKA, HIDEMI FURUSAWA, YOSHIHIKO KAMADA, YOSHIAKI SAGARA, KEISEI ANAN, KYUICHIROU MIYARA, YUICHIROU KAI, TATSUYA UGA, KAZUO TAMURA, SHOSHU MITSUYAMA and KBC-SG (Kyushu Breast Cancer-Study Group)
Anticancer Research August 2020, 40 (8) 4779-4785; DOI: https://doi.org/10.21873/anticanres.14480

The Impact of Histological Variant on Oncological Outcomes in Patients With Urothelial Carcinoma of the Bladder Treated With Radical Cystectomy
KENSHIRO TAKEMOTO, JUN TEISHIMA, YUKI KOHADA, KENICHIRO IKEDA, HIROTAKA NAGAMATSU, AKIHIRO GORIKI, SHOGO INOUE, TETSUTARO HAYASHI, MITSURU KAJIWARA and AKIO MATSUBARA
Anticancer Research August 2020, 40 (8) 4787-4793; DOI: https://doi.org/10.21873/anticanres.14481

Artificial Intelligence in Ovarian Cancer Diagnosis
MUNETOSHI AKAZAWA and KAZUNORI HASHIMOTO
Anticancer Research August 2020, 40 (8) 4795-4800; DOI: https://doi.org/10.21873/anticanres.14482

Clinical Outcomes of Surgical Resection for Brain Metastases from Non-small Cell Lung Cancer
TAKAYUKI NAKAO, TAKESHI OKUDA, HIROMASA YOSHIOKA and MITSUGU FUJITA
Anticancer Research August 2020, 40 (8) 4801-4804; DOI: https://doi.org/10.21873/anticanres.14483

　Contents

Correlation Between Radiosensitizing Activity and the Stereo-structure of the TX-2036 Series of Molecules
KAZUTO OHKURA, ATSUSHI TABATA, YOSHIHIRO UTO and HITOSHI HORI
Anticancer Research August 2019, 39 (8) 4479-4483; DOI: https://doi.org/10.21873/anticanres.13622

Expression of Matrix Metalloproteinases in Intraductal Papillary Mucinous Neoplasm of the Pancreas
MASANORI AKASHI, TORU HISAKA, HISAMUNE SAKAI, HIROTO ISHIKAWA, RYUICHI KAWAHARA, YUICHI GOTO, YORIKO NOMURA, MASAFUMI YASUNAGA, FUMIHIKO FUJITA, MASAHIKO TANIGAWA, YOSHIKI NAITO, JUN AKIBA, HIROHISA YANO, HIROYUKI TANAKA, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2019, 39 (8) 4485-4490; DOI: https://doi.org/10.21873/anticanres.13623

Significance of Elevated HMGB1 Expression in Pituitary Apoplexy
TAKESHI OKUDA, MITSUGU FUJITA and AMAMI KATO
Anticancer Research August 2019, 39 (8) 4491-4494; DOI: https://doi.org/10.21873/anticanres.13624

Zfat Is Indispensable for the Development of Erythroid Cells in the Fetal Liver
KEIKO DOI, TOSHIYUKI TSUNODA, MIDORI KOYANAGI, YOKO TANAKA, SHIORI YAMANO, AYA FUJIKANE, KENSUKE NISHI, SHUHEI ISHIKURA and SENJI SHIRASAWA
Anticancer Research August 2019, 39 (8) 4495-4502; DOI: https://doi.org/10.21873/anticanres.13625

Preventive Effect of Oral Administration of Pantoea agglomerans-derived LPS in a Hypertensive Rat Model Upon Salt Loading
RAN ZHANG, HIROYUKI INAGAWA, SACHIKO UCHIBORI, TSUTOMU MASAKI, HIDEKI KOBARA and GEN-ICHIRO SOMA
Anticancer Research August 2019, 39 (8) 4503-4509; DOI: https://doi.org/10.21873/anticanres.13626

Pollen Allergy Suppression Effect by the Oral Administration of Acetic Acid Bacteria (Gluconacetobacter hansenii)
HIROYUKI INAGAWA, TAKASHI NISHIZAWA, CHIE KOCHI, SATOKO AMANO and GEN-ICHIRO SOMA
Anticancer Research August 2019, 39 (8) 4511-4516; DOI: https://doi.org/10.21873/anticanres.13627

Usefulness of the nCounter Analysis System to Monitor Immune-related Biomarkers in PBMCs During Anti-PD-1 Therapy
TAKAFUMI MORISAKI, MAKOTO KUBO, MASAYO UMEBAYASHI, YUAN YUAN, AKIHIRO TSUYADA, HIROTO TANAKA, NORIHIRO KOYA, SHINICHIROU NAKAGAWA, TAKASHI MORISAKI and MASAFUMI NAKAMURA
Anticancer Research August 2019, 39 (8) 4517-4523; DOI: https://doi.org/10.21873/anticanres.13628

Prognostic Factors for Colorectal Cancer Patients Treated With Combination of Immune-cell Therapy and First-line Chemotherapy: A Retrospective Study
RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, ERIKO MATSUDA, HIROSHI IBE, ERI OGUMA, KEIKO NAITOH, KAORI MAKITA and SHIGENORI GOTO
Anticancer Research August 2019, 39 (8) 4525-4532; DOI: https://doi.org/10.21873/anticanres.13629

Characteristic Morphological Changes and Rapid Actin Accumulation in Serum-MAF-treated Macrophages
KUMPEI KAWAKATSU, MAMI ISHIKAWA, RIHO MASHIBA, NGOC KIET TRAN, MINORI AKAMATSU and TAKAHITO NISHIKATA
Anticancer Research August 2019, 39 (8) 4533-4537; DOI: https://doi.org/10.21873/anticanres.13630

Neoadjuvant Chemotherapy Increases PD-L1 Expression and CD8+ Tumor-infiltrating Lymphocytes in Esophageal Squamous Cell Carcinoma
EIJI FUKUOKA, KIMIHIRO YAMASHITA, TOMOKO TANAKA, RYUICHIRO SAWADA, YUTAKA SUGITA, AKIRA ARIMOTO, MITSUGU FUJITA, GOSUKE TAKIGUCHI, TAKERU MATSUDA, TARO OSHIKIRI, TETSU NAKAMURA, SATOSHI SUZUKI and YOSHIHIRO KAKEJI
Anticancer Research August 2019, 39 (8) 4539-4548; DOI: https://doi.org/10.21873/anticanres.13631

Sinusoidal Obstruction Syndrome and Postoperative Complications Resulting from Preoperative Chemotherapy for Colorectal Cancer Liver Metastasis
TORU HISAKA, HIROTO ISHIKAWA, HISAMUNE SAKAI, RYUICHI KAWAHARA, YUICHI GOTO, YORIKO NOMURA, MASAFUMI YASUNAGA, TETSUSHI KINUGASA, FUMIHIKO FUJITA, TOMOAKI MIZOBE, MASARU FUKAHORI, KEISUKE MIWA, OSAMU NAKASHIMA, MASAHIKO TANIGAWA, YOSHIKI NAITO, JUN AKIBA, HIROHISA YANO, HIROYUKI TANAKA, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2019, 39 (8) 4549-4554; DOI: https://doi.org/10.21873/anticanres.13632

Evaluating Chemotherapy-induced Nausea and Vomiting and Food Intake in Patients With Gynecologic Cancer
HIROAKI KOMATSU, TETSURO OISHI, SHINYA SATO, DAIKEN OSAKU, MAYUMI SAWADA, AKIKO KUDOH, MICHIKO NONAKA, SEIYA SATO, MUNEAKI SHIMADA, HIROAKI ITAMOCHI and TASUKU HARADA
Anticancer Research August 2019, 39 (8) 4555-4560; DOI: https://doi.org/10.21873/anticanres.13633

Clinical and Prognostic Significance of Neoplastic Spindle Cells in Gallbladder Cancer
RYUTA MIDORIKAWA, TORU HISAKA, HISAMUNE SAKAI, YORIKO NOMURA, YUICHI GOTO, TOSHIHIRO SATO, RYUICHI KAWAHARA, HIROTO ISHIKAWA, FUMIHIKO FUJITA, MASAFUMI YASUNAGA, MASAHIKO TANIGAWA, YOSHIKI NAITO, JUN AKIBA, HIROHISA YANO, HIROYUKI TANAKA, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2019, 39 (8) 4561-4568; DOI: https://doi.org/10.21873/anticanres.13634

Clinicopathological Study of Resections of Intraductal Papillary Neoplasm of the Bile Duct
TOSHIHIRO SATO, TORU HISAKA, HISAMUNE SAKAI, HIROTO ISHIKAWA, RYUICHI KAWAHARA, YUICHI GOTO, YORIKO NOMURA, MASAFUMI YASUNAGA, FUMIHIKO FUJITA, MASAHIKO TANIGAWA, YOSHIKI NAITO, JUN AKIBA, HIROHISA YANO, HIROYUKI TANAKA, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2019, 39 (8) 4569-4573; DOI: https://doi.org/10.21873/anticanres.13635

Sarcomatous Component in Pancreatic Adenosquamous Carcinoma: A Clinicopathological Series of 7 Cases
SHINICHI TANIWAKI, TORU HISAKA, HISAMUNE SAKAI, YUICHI GOTO, YORIKO NOMURA, RYUICHI KAWAHARA, HIROTO ISHIKAWA, MASAFUMI YASUNAGA, YOSHIKI NAITO, JUN AKIBA, HIROHISA YANO, HIROYUKI TANAKA, YOSHITO AKAGI and KOJI OKUDA
Anticancer Research August 2019, 39 (8) 4575-4580; DOI: https://doi.org/10.21873/anticanres.13636

Clinical Features of Recurrence in Patients Without Residual Tumour in Endometrial Cancer
DAISUKE MIYAHARA, FUSANORI YOTSUMOTO, TOYOFUMI HIRAKAWA, KENICHI YOSHIKAWA, KOICHIRO SHIGEKAWA, KOHEI MIYATA, TOMOHIRO ITO, SUNG OUK NAM, MASAMITSU KURAKAZU, YASUNOBU KANAMORI, SATOSHI AMADA and SHINGO MIYAMOTO
Anticancer Research August 2019, 39 (8) 4581-4588; DOI: https://doi.org/10.21873/anticanres.13637

　　Contents

Application of iNKT Cell-targeted Active Immunotherapy in Cancer Treatment
KIMIHIRO YAMASHITA, AKIRA ARIMOTO, MASAYASU NISHI, TOMOKO TANAKA, MITSUGU FUJITA, EIJI FUKUOKA, YUTAKA SUGITA, AKIO NAKAGAWA, HIROSHI HASEGAWA, SATOSHI SUZUKI and YOSHIHIRO KAKEJI
Anticancer Research July 2018, 38 (7) 4233-4239; DOI: https://doi.org/10.21873/anticanres.12719

Structure-associated Functional Control of TX-1877 Series by Glyco-conjugation
KAZUTO OHKURA, YUKI KAWAGUCHI, YOHEI TATEMATSU, ATSUSHI TABATA, YOSHIHIRO UTO and HITOSHI HORI
Anticancer Research July 2018, 38 (7) 4241-4245; DOI: https://doi.org/10.21873/anticanres.12720

Growth Suppression of Human Colorectal Cancer Cells with Mutated KRAS by 3-Deaza-cytarabine in 3D Floating Culture
HAO LUO, KENSUKE NISHI, SHUHEI ISHIKURA, ANTHONY SWAIN, NAOYUKI MORISHIGE, RYO YAZAKI, TAKASHI OHSHIMA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA
Anticancer Research July 2018, 38 (7) 4247-4256; DOI: https://doi.org/10.21873/anticanres.12721

Activated EphA2 Processing by MT1-MMP Is Involved in Malignant Transformation of Ovarian Tumours In Vivo
YOKO TAKAHASHI, MAKOTO HAMASAKI, MIKIKO AOKI, KAORI KOGA, NAOHIKO KOSHIKAWA, SHINGO MIYAMOTO and KAZUKI NABESHIMA
Anticancer Research July 2018, 38 (7) 4257-4266; DOI: https://doi.org/10.21873/anticanres.12722

Visualizing Energy Charge in Breast Carcinoma Tissues by MALDI Mass-spectrometry Imaging Profiles of Low-molecular-weight Metabolites
NOBUHIRO TORATA, MAKOTO KUBO, DAISUKE MIURA, KENOKI OHUCHIDA, YUSUKE MIZUUCHI, YOSHINORI FUJIMURA, EISUKE HAYAKAWA, MASAYA KAI, YOSHINAO ODA, KAZUHIRO MIZUMOTO, MAKOTO HASHIZUME and MASAFUMI NAKAMURA
Anticancer Research July 2018, 38 (7) 4267-4272; DOI: https://doi.org/10.21873/anticanres.12723

Catumaxomab with Activated T-cells Efficiently Lyses Chemoresistant EpCAM-positive Triple-negative Breast Cancer Cell Lines
MAKOTO KUBO, MASAYO UMEBAYASHI, KANAKO KURATA, HITOMI MORI, MASAYA KAI, HIDEYA ONISHI, MITSUO KATANO, MASAFUMI NAKAMURA and TAKASHI MORISAKI
Anticancer Research July 2018, 38 (7) 4273-4279; DOI: https://doi.org/10.21873/anticanres.12724

Inhibition of Survivin by Adenovirus Vector Enhanced Paclitaxel-induced Apoptosis in Breast Cancer Cells
TOSHIHIRO TANAKA and HIROAKI UCHIDA
Anticancer Research July 2018, 38 (7) 4281-4288; DOI: https://doi.org/10.21873/anticanres.12725

Evaluation of a Hypertensive Rat Model Using Peripheral Blood Neutrophil Activity, Phagocytic Activity and Oxidized LDL Evaluation
RAN ZHANG, HIROYUKI INAGAWA, KIMIKO KAZUMURA, HIROSHI TSUCHIYA, TOSHIYUKI MIWA, NAOKAZU MORISHITA, SACHIKO UCHIBORI, JUN HANASHIRO, TSUTOMU MASAKI, HIDEKI KOBARA and GEN-ICHIRO SOMA
Anticancer Research July 2018, 38 (7) 4289-4294; DOI: https://doi.org/10.21873/anticanres.12726

Phagocytic Activation of Macrophages with Serum MAF Depends on Engulfment Efficiency and Not Migratory Activity
RIHO MASHIBA, MAMI ISHIKAWA, YU SUMIYA, KUMPEI KAWAKATSU, NGOC KIET TRAN and TAKAHITO NISHIKATA
Anticancer Research July 2018, 38 (7) 4295-4298; DOI: https://doi.org/10.21873/anticanres.12727

Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein
TORU TASAKA, EMI KUWADA, YUKA IZUCHI, RYOHEI NISHIGAWA, HISATSUGU YAMADA, HIDEKI UNUMA, KEN TOKUNAGA, AKIO HAYAKAWA, AKITERU GO, KIKYO GO and YOSHIHIRO UTO
Anticancer Research July 2018, 38 (7) 4299-4304; DOI: https://doi.org/10.21873/anticanres.12728

Global Liver Gene Expression Analysis on a Murine Hepatic Steatosis Model Treated with Mulberry (Morus alba L.) Leaf Powder
HIRONOBU UCHIYAMA, KEN-ICHI KOMATSU, AKIFUMI NAKATA, KEISUKE SATO, YOSHIHIRO MIHARA, AKIRA TAKAGURI, TAKAYUKI NAGASHIMA and KOJI WAKAME
Anticancer Research July 2018, 38 (7) 4305-4311; DOI: https://doi.org/10.21873/anticanres.12729

Radiosensitizing Effect of 5-Aminolevulinic Acid and Protoporphyrin IX on Carbon-ion Beam Irradiation
TOMOKO KANEKO, MASAHIDE TOMINAGA, RISA KOUZAKI, AYAKA HANYU, KAZUKI UESHIMA, HISATSUGU YAMADA, MASAKI SUGA, TOMOHIRO YAMASHITA, TOMOAKI OKIMOTO and YOSHIHIRO UTO
Anticancer Research July 2018, 38 (7) 4313-4317; DOI: https://doi.org/10.21873/anticanres.12730

Construction of Anti-HER2 Recombinants as Targeting Modules for a Drug-delivery System Against HER2-positive Cells
QING TANG, MASAYOSHI ONITSUKA, ATSUSHI TABATA, TOSHIFUMI TOMOYASU and HIDEAKI NAGAMUNE
Anticancer Research July 2018, 38 (7) 4319-4325; DOI: https://doi.org/10.21873/anticanres.12731

Possible Application of Ascites-infiltrating Gamma-delta T Cells for Adoptive Immunotherapy
YUKI ABE, HIROHITO KOBAYASHI, YOSHIKA AKIZAWA, KEN ISHITANI, KAZUNORI HASHIMOTO and HIDEO MATSUI
Anticancer Research July 2018, 38 (7) 4327-4331; DOI: https://doi.org/10.21873/anticanres.12732

Immunosuppression Induced by Perioperative Peritonitis Promotes Lung Metastasis
AKIRA ARIMOTO, KIMIHIRO YAMASHITA, HIROSHI HASEGAWA, YUTAKA SUGITA, EIJI FUKUOKA, TOMOKO TANAKA, SATOSHI SUZUKI and YOSHIHIRO KAKEJI
Anticancer Research July 2018, 38 (7) 4333-4338; DOI: https://doi.org/10.21873/anticanres.12733

Dewaxed Brown Rice Feed Improves Fatty Liver in Obese and Diabetic Model Mice
HIROYUKI INAGAWA, TOSHIYUKI SAIKA, NAOKI NISHIYAMA, TAKASHI NISIZAWA, CHIE KOHCHI, MAYA UENOBE and GEN-ICHIRO SOMA
Anticancer Research July 2018, 38 (7) 4339-4345; DOI: https://doi.org/10.21873/anticanres.12734

Association of Serum HB-EGF Value and Response to Chemotherapy in Patients with Recurrent Ovarian Cancer
DAISUKE IZUCHI, SATOSHI FUKAGAWA, FUSANORI YOTSUMOTO, KOICHIRO SHIGEKAWA, KENICHI YOSHIKAWA, TOYOFUMI HIRAKAWA, CHIHIRO KIYOSHIMA, NAM SUNG OUK, DAICHI URUSHIYAMA, TAKAHIRO KATSUDA, KOHEI MIYATA, TOMOHIRO ITO, MASAMITSU KURAKAZU, RYOTA ARAKI, AYAKO SANUI, DAISUKE MIYAHARA, MASAHARU MURATA, HIROKO ITO, KYOKO SHIROTA, MASAHIDE KUROKI, SHIN'ICHIRO YASUNAGA and SHINGO MIYAMOTO
Anticancer Research July 2018, 38 (7) 4347-4351; DOI: https://doi.org/10.21873/anticanres.12735

Prognostic Factors for Pancreatic Cancer Patients Treated with Immune-cell Therapy
KAORI MAKITA, TAKASHI KAMIGAKI, SACHIKO OKADA, ERIKO MATSUDA, HIROSHI IBE, ERI OGUMA, KEIKO NAITOH, RISHU TAKIMOTO and SHIGENORI GOTO
Anticancer Research July 2018, 38 (7) 4353-4360; DOI: https://doi.org/10.21873/anticanres.12736

Seizures and Tumor Progression in Glioma Patients with Uncontrollable Epilepsy Treated with Perampanel
SHUICHI IZUMOTO, MASAHARU MIYAUCHI, TAKAYUKI TASAKI, TAKESHI OKUDA, NOBUHIRO NAKAGAWA, NAOKI NAKANO, AMAMI KATO and MITSUGU FUJITA
Anticancer Research July 2018, 38 (7) 4361-4366; DOI: https://doi.org/10.21873/anticanres.12737

Biweekly Administration of TAS-102 for Neutropenia Prevention in Patients with Colorectal Cancer
YOICHIRO YOSHIDA, RYOHEI SAKAMOTO, RYUJI KAJITANI, TARO MUNECHIKA, YOSHIKO MATSUMOTO, AKIRA KOMONO, NAOYA AISU, KOJIMA DAIBO, FUMIHIKO KIYOMI and SUGURU HASEGAWA
Anticancer Research July 2018, 38 (7) 4367-4373; DOI: https://doi.org/10.21873/anticanres.12738

Improvement in Protracted Wound Healing by Topical Cream Containing Lipopolysaccharide Derived from Pantoea agglomerans
ATSUTOMO MORISHIMA and HIROYUKI INAGAWA
Anticancer Research July 2018, 38 (7) 4375-4379; DOI: https://doi.org/10.21873/anticanres.12739

Efficacy and Safety of Bi-weekly Pegfilgrastim for Dose-dense Chemotherapy-induced Neutropenia in Breast Cancer Patients
HITOMI MORI, MAKOTO KUBO, MASAYA KAI, KANAKO KURATA, MAI YAMADA and MASAFUMI NAKAMURA
Anticancer Research July 2018, 38 (7) 4381-4386; DOI: https://doi.org/10.21873/anticanres.12740

Contents

KENSUKE TAJIRI, TOMOYA SUDOU, FUMIHIKO FUJITA, TORU HISAKA, TETSUSHI KINUGASA, and YOSHITO AKAGI.

Review: Clinicopathological and Corresponding Genetic Features of Colorectal Signet Ring Cell Carcinoma.

Anticancer Res July 2017 37 (7) 3817-3823.

USANORI YOTSUMOTO, SATOSHI FUKAGAWA, KOHEI MIYATA, SUNG OUK NAM, TAKAHIRO KATSUDA, DAISUKE MIYAHARA, TAKASHI ODAWARA, SADAO MANABE, TOYOKAZU ISHIKAWA, SHIN'ICHIRO YASUNAGA, and SHINGO MIYAMOTO.

HB-EGF Is a Promising Therapeutic Target for Lung Cancer with Secondary Mutation of EGFRT790M

Anticancer Res July 2017 37 (7) 3825-3831.

KENSUKE NISHI, HAO LUO, SHUHEI ISHIKURA, KEIKO DOI, YURI IWAIHARA, LAUREN WILLS, GEORGE S. BAILLIE, TOSHIFUMI SAKATA, SENJI SHIRASAWA, and TOSHIYUKI TSUNODA.

Apremilast Induces Apoptosis of Human Colorectal Cancer Cells with Mutant KRAS.

Anticancer Res July 2017 37 (7) 3833-3839.

TAKUMI YAMAJI, KOTARO SHIDE, TAKURO KAMEDA, MASAAKI SEKINE, AYAKO KAMIUNTEN, TOMONORI HIDAKA, YOKO KUBUKI, HARUKO SHIMODA, HIROO ABE, TADASHI MIIKE, HISAYOSHI IWAKIRI, YOSHIHIRO TAHARA, MITSUE SUETA, SHOJIRO YAMAMOTO, SATORU HASUIKE, KENJI NAGATA, and KAZUYA SHIMODA.

Loss of Tyrosine Kinase 2 Does Not Affect the Severity of Jak2V617F-induced Murine Myeloproliferative Neoplasm.

Anticancer Res July 2017 37 (7) 3841-3847.

KAZUTO OHKURA, YOHEI TATEMATSU, YUKI KAWAGUCHI, YOSHIHIRO UTO, and HITOSHI HORI.

Interactive Analysis of TX-1123 with Cyclo-oxygenase: Design of COX2 Selective TX Analogs.

Anticancer Res July 2017 37 (7) 3849-3854.

KENSUKE NISHI, HAO LUO, KAZUHIKO NAKABAYASHI, KEIKO DOI, SHUHEI ISHIKURA, YURI IWAIHARA, YASUHIRO YOSHIDA, KUMPEI TANISAWA, TOMIO ARAI, SEIJIRO MORI, MOTOJI SAWABE, MASAAKI MURAMATSU, MASASHI TANAKA, TOSHIFUMI SAKATA, SENJI SHIRASAWA, and TOSHIYUKI TSUNODA.

An Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids.

Anticancer Res July 2017 37 (7) 3855-3862.

TOMOKO TANAKA, MITSUGU FUJITA, HIROSHI HASEGAWA, AKIRA ARIMOTO, MASAYASU NISHI, EIJI FUKUOKA, YUTAKA SUGITA, TAKERU MATSUDA, YASUO SUMI, SATOSHI SUZUKI, YOSHIHIRO KAKEJI, and KIMIHIRO YAMASHITA.

Frequency of Myeloid-derived Suppressor Cells in the Peripheral Blood Reflects the Status of Tumor Recurrence.

Anticancer Res July 2017 37 (7) 3863-3869.

TAKESHI OKUDA, TAKAYUKI TASAKI, SUSUMU NAKATA, KIMIHIRO YAMASHITA, HIROMASA YOSHIOKA, SHUICHI IZUMOTO, AMAMI KATO, and MITSUGU FUJITA.

Efficacy of Combination Therapy with MET and VEGF Inhibitors for MET-overexpressing Glioblastoma.

Anticancer Res July 2017 37 (7) 3871-3876.

IKKYU SHIBA, RISA KOUZAKI, HISATSUGU YAMADA, YOSHIO ENDO, TAKAHISA TAKINO, HIROSHI SATO, KEIKO KITAZATO, TERUYOSHI KAGEJI, SHINJI NAGAHIRO, and YOSHIHIRO UTO.

Design and Synthesis of Novel Anti-metastatic Hypoxic Cytotoxin TX-2137 Targeting AKT Kinase.

Anticancer Res July 2017 37 (7) 3877-3883.

HIROKI KONDO, YOHEI SHIMONO, JUNKO MUKOHYAMA, YASUTERU TANAKA, NAOKI SHIBUYA, HIRONOBU MINAMI, YOSHIHIRO KAKEJI, and AKIRA SUZUKI.

Discordance of MCM7 mRNA and its Intronic MicroRNA Levels Under Hypoxia.

Anticancer Res July 2017 37 (7) 3885-3890.

SATOSHI FUKAGAWA, FUSANORI YOTSUMOTO, TAKASHI ODAWARA, SADAO MANABE, TOYOKAZU ISHIKAWA, SHIN'ICHIRO YASUNAGA, and SHINGO MIYAMOTO.

Antitumour Effects of Intravenous Administration of BK-UM, a Novel Inhibitor of HB-EGF, in Ovarian Cancer Therapy.

Anticancer Res July 2017 37 (7) 3891-3896.

RAN ZHANG, HIROYUKI INAGAWA, MASARU TAKAHASHI, HISAMI KAWANISHI, KIMIKO KAZUMURA, HIROSHI TSUCHIYA, NAOKAZU MORISHITA, YUTARO KOBAYASHI, TSUTOMU MASAKI, HIDEKI KOBARA, and GEN-ICHIRO SOMA.

Measurement of the Phagocytic Activity of Human Peripheral Blood Using a Highly Sensitive Fluorometric Detection Device Without Hemolysis.

Anticancer Res July 2017 37 (7) 3897-3903.

TOMOKO KURITA, THUY NGUYEN THI, CHIHO KOI, MIDORI MURAKAMI, SEIJI KAGAMI, HIROTO IZUMI, and TORU HACHISUGA.

Expression of N-Acetylgalactosaminyltransferase-6 Is Related to Expression of Cell Adhesion Molecules in Endometrial Cancer.

Anticancer Res July 2017 37 (7) 3905-3910.

MIDORI MURAKAMI, SEIJI KAGAMI, THUY THI NGUYEN, CHIHO KOI, TOMOKO KURITA, and TORU HACHISUGA.

Expression of Polypeptide N-Acetylgalactosaminyltransferase-6 in Epithelial Ovarian Carcinoma.

Anticancer Res July 2017 37 (7) 3911-3915.

YUTARO KOBAYASHI, HIROYUKI INAGAWA, CHIE KOHCHI, KATSUICHIRO OKAZAKI, RAN ZHANG, HIDEKI KOBARA, TSUTOMU MASAKI, and GEN-ICHIRO SOMA.

Lipopolysaccharides Derived from Pantoea agglomerans Can Promote the Phagocytic Activity of Amyloid β in Mouse Microglial Cells.

Anticancer Res July 2017 37 (7) 3917-3920.

YONEHIRO KANEMURA, MIHO SUMIDA, YOSHIKO OKITA, EMA YOSHIOKA, ATSUYO YAMAMOTO, DAISUKE KANEMATSU, YUKAKO HANDA, HAYATO FUKUSUMI, YUI INAZAWA, AI TAKADA, MASAHIRO NONAKA, SHIN NAKAJIMA, KANJI MORI, SHIGENORI GOTO, TAKASHI KAMIGAKI, TOMOKO SHOFUDA, SHUSUKE MORIUCHI, and MAMI YAMASAKI.

Systemic Intravenous Adoptive Transfer of Autologous Lymphokine-activated αβ T-Cells Improves Temozolomide-induced Lymphopenia in Patients with Glioma.

Anticancer Res July 2017 37 (7) 3921-3932.

FUMINORI ISHII, YOICHIRO YOSHIDA, YASUSHI YAMAUCHI, NAOYA AISU, DAIBO KOJIMA, TOSHIYUKI MERA, DAISUKE KATO, TOSHIHIRO TANAKA, KEIKO NAITO, KOSEI YASUMOTO, TAKASHI KAMIGAKI, SHIGENORI GOTO, YOSHIHIRO HAMADA, SATOSHI NIMURA, SHOHTA KODAMA, and SUGURU HASEGAWA.

Hepatectomy for Liver Metastases of Colorectal Cancer After Adoptive Chemoimmunotherapy Using Activated αβ T-cells.

Anticancer Res July 2017 37 (7) 3933-3939.

YOICHIRO YOSHIDA, MASAYASU NAITO, TEPPEI YAMADA, NAOYA AISU, DAIBO KOJIMA, TOSHIYUKI MERA, TOSHIHIRO TANAKA, KEIKO NAITO, KOSEI YASUMOTO, TAKASHI KAMIGAKI, SHIGENORI GOTOH, SHOHTA KODAMA, YUICHI YAMASHITA, and SUGURU HASEGAWA.

Clinical Study on the Medical Value of Combination Therapy Involving Adoptive Immunotherapy and Chemotherapy for Stage IV Colorectal Cancer (COMVI Study).

Anticancer Res July 2017 37 (7) 3941-3946.

RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, ERIKO MATSUDA, HIROSHI IBE, ERI OGUMA, KEIKO NAITOH, KAORI MAKITA, and SHIGENORI GOTO.

Efficacy of Adoptive Immune-cell Therapy in Patients with Advanced Gastric Cancer: A Retrospective Study.

Anticancer Res July 2017 37 (7) 3947-3954.

KOHEI MIYATA, FUSANORI YOTSUMOTO, SATOSHI FUKAGAWA, CHIHIRO KIYOSHIMA, NAM SUNG OUK, DAICHI URUSHIYAMA, TOMOHIRO ITO, TAKAHIRO KATSUDA, MASAMITSU KURAKAZU, RYOTA ARAKI, AYAKO SANUI, DAISUKE MIYAHARA, MASAHARU MURATA, KYOKO SHIROTA, HIROSHI YAGI, TADAO TAKONO, KIYOKO KATO, NOBUO YAEGASHI, KOHEI AKAZAWA, MASAHIDE KUROKI, SHIN'ICHIRO YASUNAGA, and SHINGO MIYAMOTO.

Serum Heparin-binding Epidermal Growth Factor-like Growth Factor (HB-EGF) as a Biomarker for Primary Ovarian Cancer.

Anticancer Res July 2017 37 (7) 3955-3960.

TETSUSHI KINUGASA, TOMOAKI MIZOBE, SACHIKO SHIRAIWA, YOSHITO AKAGI, and KAZUO SHIROUZU.

Perineural Invasion Is a Prognostic Factor and Treatment Indicator in Patients with Rectal Cancer Undergoing Curative Surgery: 2000-2011 Data from a Single-center Study.

Anticancer Res July 2017 37 (7) 3961-3968.

HIROMASA KOBAYASHI, MAKOTO HAMASAKI, TAKASHI MORISHITA, TOORU INOUE, and KAZUKI NABESHIMA.

Analysis of Evolving Clinicopathological Features of Metastatic Brain Tumors Over 30 Years of Surgical Management.

Anticancer Res July 2017 37 (7) 3969-3974.

KAZUNORI HASHIMOTO, YU HORIBE, JIRO EZAKI, TOSHIYUKI KANNO, NOBUKO TAKAHASHI, YOSHIKA AKIZAWA, HIDEO MATSUI, TOMOKO YAMAMOTO, and NORIYUKI SHIBATA.

Laparoscopically Removed Streak Gonad Revealed Gonadoblastoma in Frasier Syndrome.

Anticancer Res July 2017 37 (7) 3975-3979.

Contents

YUICHI MINE, HAFSA MUNIR, YOICHI NAKANISHI, and DAISUKE SUGIYAMA.

Review: Biomimetic Peptides for the Treatment of Cancer.

Anticancer Res. 2016 July; 36(7): 3565-3570.

TAKAYUKI TASAKI, MITSUGU FUJITA, TAKESHI OKUDA, AZUSA YONESHIGE, SUSUMU NAKATA, KIMIHIRO YAMASHITA, HIROMASA YOSHIOKA, SHUICHI IZUMOTO, and AMAMI KATO.

MET Expressed in Glioma Stem Cells Is a Potent Therapeutic Target for Glioblastoma Multiforme.

Anticancer Res. 2016 July; 36(7): 3571-3577.

KAZUNORI HASHIMOTO, KAZUHO HONDA, HIDEO MATSUI, YOJI NAGASHIMA, and HIDEAKI ODA.

Flow Cytometric Analysis of Ovarian Cancer Ascites: Response of Mesothelial Cells and Macrophages to Cancer.

Anticancer Res. 2016 July; 36(7): 3579-3584.

HAO LUO, MASAYO UMEBAYASHI, KEIKO DOI, TAKASHI MORISAKI, SENJI SHIRASAWA, and TOSHIYUKI TSUNODA.

Resveratrol Overcomes Cellular Resistance to Vemurafenib Through Dephosphorylation of AKT in BRAF-mutated Melanoma Cells.

Anticancer Res. 2016 July; 36(7): 3585-3589.

YUSUKE KAWASHIMA, TORU HISAKA, HIROYUKI HORIUCHI, HIROTO ISHIKAWA, SHINJI UCHIDA, TETSUSHI KINUGASA, DAIMEI ETOU, KOUJI OKUDA, and YOSHITO AKAGI.

The Organo- and Cytoprotective Effects of Heat-shock Protein in Response to Injury Due to Radiofrequency Ablation in Rat Liver.

Anticancer Res. 2016 July; 36(7): 3591-3597.

HIROYUKI INAGAWA, TOSHIYUKI SAIKA, TAKASHI NISIZAWA, CHIE KOHCHI, MAYA UENOBE, and GEN-ICHIRO SOMA.

Dewaxed Brown Rice Contains a Significant Amount of Lipopolysaccharide Pointing to Macrophage Activation via TLRs.

Anticancer Res. 2016 July; 36(7): 3599-3605.

YOSHIKI SHIMAMURA, DAI TAMATANI, SYOTA KUNIYASU, YUSUKE MIZUKI, TAKUMA SUZUKI, HANAYO KATSURA, HISATSUGU YAMADA, YOSHIO ENDO, TOMOHIRO OSAKI, MASAHIRO ISHIZUKA, TOHRU TANAKA, NOBUYASU YAMANAKA, TSUKASA KURAHASHI, and YOSHIHIRO UTO.

5-Aminolevulinic Acid Enhances Ultrasound-mediated Antitumor Activity via Mitochondrial Oxidative Damage in Breast Cancer.

Anticancer Res. 2016 July; 36(7): 3607-3612.

RAN ZHANG, YUTARO KOBAYASHI, KIMIKO KAZUMURA, HIROSHI TSUCHIYA, NAOKAZU MORISHITA, HIROYUKI INAGAWA, and GEN-ICHIRO SOMA.

Development of an Evaluation Device for Phagocytic Activity of New Phagocytes Using Simple and pH-sensitive Particles that Do Not Require Pre-treatment.

Anticancer Res. 2016 July; 36(7): 3613-3618.

YU SUMIYA, TAKAHIRO INOUE, MAMI ISHIKAWA, TOSHIO INUI, DAISUKE KUCHIIKE, KENTARO KUBO, YOSHIHIRO UTO, and TAKAHITO NISHIKATA.

Macrophages Exhibit a Large Repertoire of Activation States via Multiple Mechanisms of Macrophage-activating Factors.

Anticancer Res. 2016 July; 36(7): 3619-3623.

ANTHONY SWAIN, KASEM KULKEAW, YUKA TANAKA, YOICHI NAKANISHI, SENJI SHIRASAWA, and DAISUKE SUGIYAMA.

DBA Lectin Binds to Highly Proliferative Mouse Erythroleukemia Cells.

Anticancer Res. 2016 July; 36(7): 3625-3633.

RYOHEI KOIDE, KASEM KULKEAW, YUKA TANAKA, ANTHONY SWAIN, YOICHI NAKANISHI, and DAISUKE SUGIYAMA.

Aryl Hydrocarbon Receptor Antagonist StemRegenin 1 Promotes the Expansion of Human Promyelocytic Leukemia Cell Line, NB4.

Anticancer Res. 2016 July; 36(7): 3635-3643.

KAZUTO OHKURA, YUKI KAWAGUCHI, YOHEI TATEMATSU, YOSHIHIRO UTO, and HITOSHI HORI.

An Antitumor 2-Hydroxyarylidene-4-cyclopentene-1,3-Dione as a Protein Tyrosine Kinase Inhibitor: Interaction Between TX-1123 Derivatives and Src Kinase.

Anticancer Res. 2016 July; 36(7): 3645-3649.

SUNG OUK NAM, FUSANORI YOTSUMOTO, KOHEI MIYATA, SATOSHI FUKAGAWA, TAKASHI ODAWARA, SADAO MANABE, TOYOKAZU ISHIKAWA, MASAHIDE KUROKI, SHIN'ICHIRO YASUNAGA, and SHINGO MIYAMOTO.

Anti-tumor Effect of Intravenous Administration of CRM197 for Triple-negative Breast Cancer Therapy.

Anticancer Res. 2016 July; 36(7): 3651-3657.

KIMIHIRO YAMASHITA, HIROSHI HASEGAWA, MITSUGU FUJITA, MASAYASU NISHI, TOMOKO TANAKA, AKIRA ARIMOTO, SATOSHI SUZUKI, TAKASHI KAMIGAKI, and YOSHIHIRO KAKEJI.

Host CD40 Is Essential for DCG Treatment Against Metastatic Lung Cancer.

Anticancer Res. 2016 July; 36(7): 3659-3665.

HIROSHI HASEGAWA, KIMIHIRO YAMASHITA, DAI OTSUBO, and YOSHIHIRO KAKEJI.

Liver Injury After Invariant NKT Cell Activation by Free Alpha-galactosylceramide and Alpha-galactosylceramide-loaded Dendritic Cells.

Anticancer Res. 2016 July; 36(7): 3667-3672.

MIKI SAKAUE, KAZUHISA MAEDA, SATOSHI OHNO, and TOSHINORI ITO.

Screening for Identification of Personalized Food to Promote Adiponectin Secretion in Patients with Cancer.

Anticancer Res. 2016 July; 36(7): 3673-3677.

JUNKO MUKOHYAMA, YOHEI SHIMONO, KIMIHIRO YAMASHITA, YASUO SUMI, TORU MUKOHARA, HIRONOBU MINAMI, and YOSHIHIRO KAKEJI.

Effect of Xenotransplantation Site on MicroRNA Expression of Human Colon Cancer Stem Cells.

Anticancer Res. 2016 July; 36(7): 3679-3686.

KOJI WAKAME, HIROSHI OKAWA, KEN-ICH KOMATSU, AKIFUMI NAKATA, KEISUKE SATO, HIROYUKI INGAWA, CHIE KOHCHI, TAKASHI NISHIZAWA, and GEN-ICHIRO SOMA.

Immunopotentiator from Pantoea agglomerans 1 (IP-PA1) Promotes Murine Hair Growth and Human Dermal Papilla Cell Gene Expression.

Anticancer Res. 2016 July; 36(7): 3687-3692.

YUTARO KOBAYASHI, HIROYUKI INAGAWA, CHIE KOHCHI, KATSUICHIRO OKAZAKI, RAN ZHANG, and GEN-ICHIRO SOMA.

Effect of Lipopolysaccharide Derived from Pantoea agglomerans on the Phagocytic Activity of Amyloid β by Primary Murine Microglial Cells.

Anticancer Res. 2016 July; 36(7): 3693-3698.

TERUKO HONDA and HIROYUKI INAGAWA.

Gene Expression in Lipopolysaccharide-treated Human Monocytes Following Interaction with Hepatic Cancer Cells.

Anticancer Res. 2016 July; 36(7): 3699-3704.

HIRONOBU UCHIYAMA, KAORI UEHARA, TAKAYUKI NAGASHIMA, AKIFUMI NAKATA, KEISUKE SATO, YOSHIHIRO MIHARA, KEN-ICH KOMATSU, JUN TAKANARI, SHIGEOMI SHIMIZU, and KOJI WAKAME.

Global Liver Gene Expression Analysis on a Murine Metabolic Syndrome Model Treated by Low-molecular-weight Lychee Fruit Polyphenol (Oligonol®).

Anticancer Res. 2016 July; 36(7): 3705-3713.

KEIKO NAITOH, TAKASHI KAMIGAKI, ERIKO MATSUDA, HIROSHI IBE, SACHIKO OKADA, ERI OGUMA, YOSHIHIRO KINOSHITA, RISHU TAKIMOTO, KAORI MAKITA, SHUN OGASAWARA, and SHIGENORI GOTO.

Immunohistochemical Analysis of WT1 Antigen Expression in Various Solid Cancer Cells.

Anticancer Res. 2016 July; 36(7): 3715-3724.

DAISUKE MIYAHARA, TAKAHIRO KATSUTA, MIYAKO MAEHARA, YOKO TAKAHASHI, SATOSHI FUKAGAWA, KOUHEI MIYATA, CHIHIRO KIYOSHIMA, FUSANORI YOTSUMOTO, HARUCHIKA ANAN, and SHINGO MIYAMOTO.

Safety and Anti-tumor Effects of Docetaxel Plus Cisplatin in Intermediate- and High-risk Endometrial Cancer.

Anticancer Res. 2016 July; 36(7): 3725-3729.

KAZUTOMO YAMASAKI, TOSHIYUKI MATSUI, TAKASHI HISABE, YUTAKA YANO, FUMIHITO HIRAI, TSUYOSHI MOROKUMA, YASUSHI IWAO, TAKAYUKI MATSUMOTO, HIDEHISA OHI, AKIRA ANDOH, MOTOHIRO ESAKI, KUNIHIKO AOYAGI, AKIRA SUGITA, HIROSHI NAKASE, MIKIHIRO FUJIYA, DAIJIRO HIGASHI1, and KITARO FUTAMI.

Retrospective Analysis of Growth Speed of 54 Lesions of Colitis-associated Colorectal Neoplasia.

Anticancer Res. 2016 July; 36(7): 3731-3740.

YOICHIRO YOSHIDA, MASAYASU NAITO, TEPPEI YAMADA, NAOYA AISU, KOJIMA DAIBO, TOSHIYUKI MERA, TOSHIHIRO TANAKA, KEIKO NAITO, KOSEI YASUMOTO, TAKASHI KAMIGAKI, SHIGENORI GOTO, YUICHI YAMASHITA, and SUGURU HASEGAWA.

Adoptive Chemoimmunotherapy Using Activated αβ T Cells for Stage IV Colorectal Cancer.

Anticancer Res. 2016 July; 36(7): 3741-3746.

ATSUTOMO MORISHIMA and HIROYUKI INAGAWA.

Clinical Effects of Orally Administered Lipopolysaccharide Derived from Pantoea agglomerans on Malignant Tumors.

Anticancer Res. 2016 July; 36(7): 3747-3751.

ASUKA YASUEDA, SHINICHIRO SHINZAKI, HIDEKI IIJIMA, TSUNEKAZU MIZUSHIMA, JUNICHI NISHIMURA, SATOSHI HIYAMA, SATOSHI OHNO, and TOSHINORI ITO.

Safety of Emulsifying Lipid Formulation Containing Omega-3 Polyunsaturated Fatty Acids for Patients with Crohn's Disease.

Anticancer Res. 2016 July; 36(7): 3753-3759.

DAIJIRO HIGASHI, HIDETOSHI KATSUNO, HIDEAKI KIMURA, KENICHI TAKAHASHI, HIROKI IKEUCHI, TORU KONO, RIICHIRO NEZU, KATSUYOSHI HATAKEYAMA, HITOSHI KAMEYAMA, IWAO SASAKI, KOUHEI FUKUSHIMA, KAZUHIRO WATANABE, MASATO KUSUNOKI, TOSHIMITSU ARAKI, KIYOSHI MAEDA, SHINGO KAMEOKA, MICHIO ITABASHI, SAYUMI NAKAO, KOUTARO MAEDA, HIROKI OHGE, YUSUKE WATADANI, TOSHIAKI WATANABE, EIJI SUNAMI, MASAYUKI HOTOKEZAKA, AKIRA SUGITA, YUJI FUNAYAMA, and KITARO FUTAMI.

Current State of and Problems Related to Cancer of the Intestinal Tract Associated with Crohn's Disease in Japan.

Anticancer Res. 2016 July; 36(7): 3761-3766.

TOSHIO INUI, HARUKA AMITANI, KENTARO KUBO, DAISUKE KUCHIIKE, YOSHIHIRO UTO, TAKAHITO NISHIKATA, and MARTIN METTE.

Case Report: A Non-small Cell Lung Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Tumor Treating Fields.

Anticancer Res. 2016 July; 36(7): 3767-3770.

TOSHIO INUI, GORO KATSUURA, KENTARO KUBO, DAISUKE KUCHIIKE, LESLYE CHENERY, YOSHIHIRO UTO, TAKAHITO NISHIKATA, and MARTIN METTE.

Case Report: GcMAF Treatment in a Patient with Multiple Sclerosis.

Anticancer Res. 2016 July; 36(7): 3771-3774.

DAIMEI ETO, TORU HISAKA, HIROYUKI HORIUCHI, SHINJI UCHIDA, HIROTO ISHIKAWA, YUSUKE KAWASHIMA, TETSUSHI KINUGASA, OSAMU NAKASHIMA, HIROHISA YANO, KOJI OKUDA, and YOSHITO AKAGI.

Expression of HSP27 in Hepatocellular Carcinoma.

Anticancer Res. 2016 July; 36(7): 3775-3779.

SACHIKO SHIRAIWA, TETSUSHI KINUGASA, AKIHIKO KAWAHARA, TOMOAKI MIZOBE, TAKAFUMI OHCHI, KOTARO YUGE, SHINYA FUJINO, MITSUHIRO KATAGIRI, SUSUMU SHIMOMURA, KENSUKE TAJIRI, TOMOYA SUDO, MASAYOSHI KAGE, MICHIHIKO KUWANO, and YOSHITO AKAGI.

Nuclear Y-Box-binding Protein-1 Expression Predicts Poor Clinical Outcome in Stage III Colorectal Cancer.

Anticancer Res. 2016 July; 36(7): 3781-3788.

Contents

MASAMICHI TOMONAGA.

Preface.

Anticancer Res. 2015 August; 35(8): 4383.

TSUKASA SEYA, HIROAKI SHIME, MISAKO MATSUMOTO.

Functional Alteration of Tumor-infiltrating Myeloid Cells in RNA Adjuvant Therapy.

Anticancer Res. 2015 August; 35(8): 4385-4392. Review.

GEN-ICHIRO SOMA, HIROYUKI INAGAWA.

Methods to Prevent or Treat Refractory Diseases by Focusing on Intestinal Microbes Using LPS and Macrophages.

Anticancer Res. 2015 August; 35(8): 4393-4396. Review.

YOJIRO KOTAKE, MADOKA NAEMURA, CHIHIRO MURASAKI, YASUTOSHI INOUE, HARUNA OKAMOTO.

Transcriptional Regulation of the p16 Tumor Suppressor Gene.

Anticancer Res. 2015 August; 35(8): 4397-4401. Review.

NAOHIRO YOSHIDA, TETSUSHI KINUGASA, KOICHI OHSHIMA, KOTARO YUGE, TAKAFUMI OHCHI, SHINYA FUJINO, SACHIKO SHIRAIWA, MITSUHIRO KATAGIRI, YOSHITO AKAGI.

Analysis of Wnt and β-catenin Expression in Advanced Colorectal Cancer.

Anticancer Res. 2015 August; 35(8): 4403-4410.

ATSUSHI TABATA, YUKIMASA OHKUBO, NATSUKI ANYOJI, KEIKO HOJO, TOSHIFUMI TOMOYASU, YOUHEI TATEMATSU, KAZUTO OHKURA, HIDEAKI NAGAMUNE.

Development of a Sortase A-mediated Peptide-labeled Liposome Applicable to Drug-delivery Systems.

Anticancer Res. 2015 August; 35(8): 4411-4417.

YURI IWAIHARA, SHUHEI ISHIKURA, KEIKO DOI, TOSHIYUKI TSUNODA, TAKAHIRO FUJIMOTO, TADASHI OKAMURA, SENJI SHIRASAWA.

Marked Reduction in FoxO1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells.

Anticancer Res. 2015 August; 35(8): 4419-4423.

DAI OTSUBO, KIMIHIRO YAMASHITA, MITSUGU FUJITA, MASAYASU NISHI, YUTAKA KIMURA, HIROSHI HASEGAWA, SATOSHI SUZUKI, YOSHIHIRO KAKEJI.

Early-phase Treatment by Low-dose 5-Fluorouracil or Primary Tumor Resection Inhibits MDSC-mediated Lung Metastasis Formation.

Anticancer Res. 2015 August; 35(8): 4425-4431.

SUNG OUK NAM, FUSANORI YOTSUMOTO, KOHEI MIYATA, RYOTA SOUZAKI, TOMOAKI TAGUCHI, MASAHIDE KUROKI, SHINGO MIYAMOTO.

Validity of HB-EGF as Target for Human Neuroblastoma Therapy.

Anticancer Res. 2015 August; 35(8): 4433-4440.

TAKAHIRO INOUE, MAMI ISHIKAWA, YU SUMIYA, HARUKA KOHDA, TOSHIO INUI, DAISUKE KUCHIIKE, KENTARO KUBO, YOSHIHIRO UTO, TAKAHITO NISHIKATA.

Establishment of a Macrophage-activating Factor Assay System Using the Human Monocytic Cell Line THP-1.

Anticancer Res. 2015 August; 35(8): 4441-4445.

YU SUMIYA, MAMI ISHIKAWA, TAKAHIRO INOUE, TOSHIO INUI, DAISUKE KUCHIIKE, KENTARO KUBO, YOSHIHIRO UTO, TAKAHITO NISHIKATA.

Macrophage Activation Mechanisms in Human Monocytic Cell Line-derived Macrophages.

Anticancer Res. 2015 August; 35(8): 4447-4451.

TOSHIYUKI TSUNODA, SHUHEI ISHIKURA, KEIKO DOI, YURI IWAIHARA, HIROMASA HIDESIMA, HAO LUO, YUMIKO HIROSE, SENJI SHIRASAWA.

Establishment of a Three-dimensional Floating Cell Culture System for Screening Drugs Targeting KRAS-mediated Signaling Molecules.

Anticancer Res. 2015 August; 35(8): 4453-4459.

TSUTOMU KOMORI, KEIKO SAITO, NORIYUKI SAWA, YASUHIRO SHIBASAKI, CHIE KOHCHI, GEN-ICHIRO SOMA, HIROYUKI INAGAWA.

Innate Immunity Activated by Oral Administration of LPSp Is Phylogenetically Preserved and Developed in Broiler Chickens.

Anticancer Res. 2015 August; 35(8): 4461-4466.

YUKI TAMURA, HIROYUKI INAGAWA, YOKO NAKATA, CHIE KOHCHI, GEN-ICHIRO SOMA.

Effects of the Subaleurone Layer of Rice on Macrophage Activation and Protection of Pollen Allergy in a Murine Model.

Anticancer Res. 2015 August; 35(8): 4467-4472.

TERUKO HONDA, HIROYUKI INAGAWA.

Molecular Response of Human Monocytes Following Interaction with Colon Cancer Cells by Pre-treatment with Low-dose Lipopolysaccharide.

Anticancer Res. 2015 August; 35(8): 4473-4477.

AKANE YONEHARA, YUKA TANAKA, KASEM KULKEAW, TAKUMI ERA, YOICHI NAKANISHI, DAISUKE SUGIYAMA.

Aloe vera Extract Suppresses Proliferation of Neuroblastoma Cells In Vitro.

Anticancer Res. 2015 August; 35(8): 4479-4485.

YOSHIHIRO UTO, TOMOHITO KAWAI, TOSHIHIDE SASAKI, KEN HAMADA, HISATSUGU YAMADA, DAISUKE KUCHIIKE, KENTARO KUBO, TOSHIO INUI, MARTIN METTE, KEN TOKUNAGA, AKIO HAYAKAWA, AKITERU GO, TOMOHIRO OOSAKI.

Degalactosylated/Desialylated Bovine Colostrum Induces Macrophage Phagocytic Activity Independently of Inflammatory Cytokine Production.

Anticancer Res. 2015 August; 35(8): 4487-4492.

NAOKO KOJIMA, YUKA TANAKA, KASEM KULKEAW, YOICHI NAKANISHI, SENJI SHIRASAWA, DAISUKE SUGIYAMA.

Apoptosis-inducing Factor, Mitochondrion-associated 2, Regulates Klf1 in a Mouse Erythroleukemia Cell Line.

Anticancer Res. 2015 August; 35(8): 4493-4499.

KOJI WAKAME, KEN-ICHI KOMATSU, HIROYUKI INAGAWA, TAKASHI NISHIZAWA.

Immunopotentiator from Pantoea agglomerans Prevents Atopic Dermatitis Induced by Dermatophagoides farinae Extract in NC/Nga Mouse.

Anticancer Res. 2015 August; 35(8): 4501-4508.

SATOKO AMANO, HIROYUKI INAGAWA, YOKO NAKATA, MASAKI OHMORI, CHIE KOHCHI, GEN-ICHIRO SOMA.

Oral Administration of Lipopolysaccharide of Acetic Acid Bacteria Protects Pollen Allergy in a Murine Model.

Anticancer Res. 2015 August; 35(8): 4509-4514.

YUKI KAWAGUCHI, YOHEI TATEMATSU, ATSUSHI TABATA, HIDEAKI NAGAMUNE, KAZUTO OHKURA.

Cytolytic Activity and Molecular Feature of Cardiotoxin and Cardiotoxin-like Basic Protein: The Electrostatic Potential Field Is an Important Factor for Cell Lytic Activity.

Anticancer Res. 2015 August; 35(8): 4515-4519.

DAISUKE MIYAHARA, TAEKO UEDA, TAKAHIRO KATSUDA, MIYAKO MAEHARA, SATOSHI FUKAGAWA, KOHEI MIYATA, SUNG OUK NAM, HARUHIKO KONDO, SHINGO MIYAMOTO.

The Safety of Pegylated Liposomal Doxorubicin Plus Irinotecan in Recurrent Ovarian Cancer Patients: A Phase I Trial.

Anticancer Res. 2015 August; 35(8): 4521-4525.

MIYAKO MAEHARA, TAEKO UEDA, DAISUKE MIYAHARA, YOKO TAKAHASHI, KOHEI MIYATA, SUNG OUK NAM, TAKAHIRO KATSUDA, HARUHIKO KONDO, SHINGO MIYAMOTO.

Clinical Efficacy of Aprepitant in Patients with Gynecological Cancer after Chemotherapy Using Paclitaxel and Carboplatin.

Anticancer Res. 2015 August; 35(8): 4527-4534.

TAKASHI KAMIGAKI, HIROSHI IBE, SACHIKO OKADA, ERIKO MATSUDA, MASANORI TANAKA, ERI OGUMA, YOSHIHIRO KINOSHITA, SHUN OGASAWARA, ATSUKO ONO, KAORI MAKITA, KEIKO NAITOH, SHIGENORI GOTO.

Improvement of Impaired Immunological Status of Patients with Various Types of Advanced Cancers by Autologous Immune Cell Therapy.

Anticancer Res. 2015 August; 35(8): 4535-4543.

TOSHIO INUI, KENTARO KUBO, DAISUKE KUCHIIKE, YOSHIHIRO UTO, TAKAHITO NISHIKATA, NORIHIRO SAKAMOTO, MARTIN METTE.

Oral Colostrum Macrophage-activating Factor for Serious Infection and Chronic Fatigue Syndrome: Three Case Reports.

Anticancer Res. 2015 August; 35(8): 4545-4549.

TOMOKI SUMIDA, NARUTO OTAWA, YU KAMATA, TOMOHIRO YAMADA, KENICHIRO UCHIDA, HIROYUKI NAKANO, HIROYUKI HAMAKAWA, TETSUYA YAMAMOTO, YOSHIYA UEYAMA, YOSHIHIDE MORI.

A Clinical Investigation of Oral Sarcomas at Multi-institutions Over the Past 30 Years.

Anticancer Res. 2015 August; 35(8): 4551-4555.

Contents

MASAMICHI TOMONAGA.

Preface.

Anticancer Res. 2014 August; 34(8): 4479.

MASAHIDE KUROKI, NAOTO SHIRASU.

Novel Treatment Strategies for Cancer and Their Tumor-targeting Approaches Using Antibodies Against Tumor-associated Antigens.

Anticancer Res. 2014 August; 34(8): 4481-4488. Review.

KEIKO DOI, SHUHEI ISHIKURA, SENJI SHIRASAWA.

The Roles of ZFAT in Thymocyte Differentiation and Homeostasis of Peripheral Naive T-Cells.

Anticancer Res. 2014 August; 34(8): 4489-4495. Review.

HIROYUKI INAGAWA, CHIE KOHCHI, GEN-ICHIRO SOMA.

Usefulness of Oral Administration of Lipopolysaccharide for Disease Prevention Through the Induction of Priming in Macrophages.

Anticancer Res. 2014 August; 34(8): 4497-4501. Review.

RYU TADA, YOSHIHIRO UTO, SHIN-ICHIRO MASUNAGA, YUKO KINASHI, KOJI ONO, HITOSHI HORI.

An NDT Study of a Boron Tracedrug UTX-51 for Glycated BSA as an AGE Model.

Anticancer Res. 2014 August; 34(8): 4503-4507.

MASAYO UMEBAYASHI, AKIFUMI KIYOTA, NORIHIRO KOYA, HIROTO TANAKA, HIDEYA ONISHI, MITSUO KATANO, TAKASHI MORISAKI.

An Epithelial Cell Adhesion Molecule- and CD3-Bispecific Antibody Plus Activated T-Cells Can Eradicate Chemoresistant Cancer Stem-like Pancreatic Carcinoma Cells In Vitro.

Anticancer Res. 2014 August; 34(8): 4509-4519.

ATSUSHI TABATA, NATSUKI ANYOJI, YUKIMASA OHKUBO, TOSHIFUMI TOMOYASU, HIDEAKI NAGAMUNE.

Investigation on the Reaction Conditions of Staphylococcus aureus Sortase A for Creating Surface-modified Liposomes as a Drug-delivery System Tool.

Anticancer Res. 2014 August; 34(8): 4521-4527.

TAKASHI MORISAKI, TATSUYA HIRANO, NORIHIRO KOYA, AKIFUMI KIYOTA, HIROTO TANAKA, MASAYO UMEBAYASHI, HIDEYA ONISHI, MITSUO KATANO.

NKG2D-directed Cytokine-activated Killer Lymphocyte Therapy Combined with Gemcitabine for Patients with Chemoresistant Metastatic Solid Tumors.

Anticancer Res. 2014 August; 34(8): 4529-4538.

TOMOKO INOUE, ANTHONY SWAIN, YOICHI NAKANISHI, DAISUKE SUGIYAMA.

Multicolor Analysis of Cell Surface Marker of Human Leukemia Cell Lines Using Flow Cytometry.

Anticancer Res. 2014 August; 34(8): 4539-4550.

TOSHIYUKI TSUNODA, SHUHEI ISHIKURA, KEIKO DOI, HIROSHI MATSUZAKI, YURI IWAIHARA, SENJI SHIRASAWA.

Resveratrol Induces Luminal Apoptosis of Human Colorectal Cancer HCT116 Cells in Three-dimensional Culture.

Anticancer Res. 2014 August; 34(8): 4551-4555.

HITOSHI HORI, RYU TADA, YOSHIHIRO UTO, EIJI NAKATA, TAKASHI MORII, KAI MASUDA.

A Neutron Dynamic Therapy with a Boron Tracedrug UTX-51 Using a Compact Neutron Generator.

Anticancer Res. 2014 August; 34(8): 4557-4560.

YUKA TANAKA, KASEM KULKEAW, TOMOKO INOUE, KEAI SINN TAN, YOICHI NAKANISHI, SENJI SHIRASAWA, DAISUKE SUGIYAMA.

Dok2 Likely Down-regulates Klf1 in Mouse Erythroleukemia Cells.

Anticancer Res. 2014 August; 34(8): 4561-4567.

YOSHIAKI ISHIBASHI, TETSUSHI KINUGASA, YOSHITO AKAGI, TAKAFUMI OHCHI, YUKITO GOTANDA, NATSUKI TANAKA, SHINYA FUJINO, KOTARO YUGE, SHIRO KIBE, NAOHIRO YOSHIDA, TOMOAKI MIZOBE, YOSUKE OKA, TAKEFUMI YOSHIDA, KAZUO SHIROUZU.

Minichromosome Maintenance Protein 7 Is a Risk Factor for Recurrence in Patients with Dukes C Colorectal Cancer.

Anticancer Res. 2014 August; 34(8): 4569-4575.

MAMI ISHIKAWA, TAKAHIRO INOUE, TOSHIO INUI, DAISUKE KUCHIIKE, KENTARO KUBO, YOSHIHIRO UTO, TAKAHITO NISHIKATA.

A Novel Assay System for Macrophage-activating Factor Activity Using a Human U937 Cell Line.

Anticancer Res. 2014 August; 34(8): 4577-4581.

YOSHIHIRO UTO, DAI TAMATANI, YUSUKE MIZUKI, YOSHIO ENDO, IKUO NAKANISHI, KEI OHKUBO, SHUNICHI FUKUZUMI, MASAHIRO ISHIZUKA, TOHRU TANAKA, DAISUKE KUCHIIKE, KENTARO KUBO, TOSHIO INUI, HITOSHI HORI.

Evaluation of the Sonosensitizing Activities of 5-Aminolevulinic Acid and Sn(IV) Chlorin e6 in Tumor-bearing Chick Embryos.

Anticancer Res. 2014 August; 34(8): 4583-4587.

TOSHIO INUI, KAORI MAKITA, HIRONA MIURA, AKIKO MATSUDA, DAISUKE KUCHIIKE, KENTARO KUBO, MARTIN METTE, YOSHIHIRO UTO, TAKAHITO NISHIKATA, HITOSHI HORI, NORIHIRO SAKAMOTO.

A Breast Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Hormone Therapy.

Anticancer Res. 2014 August; 34(8): 4589-4593. Case Report.

DAIJIRO HIGASHI, YUJI EGAWA, YUKIKO HIRANO, KIMIKAZU HIRANO, TORU MIYAKE, HIROYUKI TAKAHASHI, SHUGO UWATOKO, SOSEI ABE, SATOSHI YAMAMOTO, KOJI MIKAMI, KITARO FUTAMI, TAKAFUMI MAEKAWA, RYUICHI INOUE, MOTOYASU MIYAZAKI.

Efficacy and Safety of Irinotecan Plus S-1 (IRIS) Therapy to Treat Advanced/Recurrent Colorectal Cancer.

Anticancer Res. 2014 August; 34(8): 4595-4599.

TAKASHI KAMIGAKI, ERIKO MATSUDA, SACHIKO OKADA, KEIKO NAITOH, TAKASHIGE KONDO, HIROSHI IBE, RYUJI MAEKAWA, SHIGENORI GOTO.

Prospective Evaluation of Safety of Immune-cell Therapy for Patients with Various Types of Advanced Cancer.

Anticancer Res. 2014 August; 34(8): 4601-4607.

TERUKO HONDA, HIROYUKI INAGAWA, ISAMU YAMAMOTO.

Expression of Chemotaxis- and Angiogenesis-related Factors in Human Monocytes Following Interaction with Colon Cancer Cells Is Suppressed by Low-dose Lipopolysaccharide.

Anticancer Res. 2014 August; 34(8): 4609-4613.

SUNG OUK NAM, FUSANORI YOTSUMOTO, KOHEI MIYATA, YUKI SUZAKI, HIROSHI YAGI, TAKASHI ODAWARA, SADAO MANABE, TOYOKAZU ISHIKAWA, MASAHIDE KUROKI, EISUKE MEKADA, SHINGO MIYAMOTO.

Pre-clinical Study of BK-UM, a Novel Inhibitor of HB-EGF, for Ovarian Cancer Therapy.

Anticancer Res. 2014 August; 34(8): 4615-4620.

MASATAKA OITA, YOSHIHIRO UTO, MASAHIDE TOMINAGA, MOTOHARU SASAKI, YASUO HARA, TARO KISHI, HITOSHI HORI.

Radiosensitivity Uncertainty Evaluation for the In Vitro Biophysical Modeling of EMT6 Cells.

Anticancer Res. 2014 August; 34(8): 4621-4626.

YUKI KAWAGUCHI, ATSUSHI TABATA, HIDEAKI NAGAMUNE, KAZUTO OHKURA.

Molecular Analysis of Streptococcus anginosus-derived SagA Peptides.

Anticancer Res. 2014 August; 34(8): 4627-4631.

TETSUSHI KINUGASA, YOSHITO AKAGI, KAZUO SHIROUZU.

Benefit of Lateral Lymph Node Dissection for Rectal Cancer: Long-term Analysis of 944 Cases Undergoing Surgery at a Single Center (1975-2004).

Anticancer Res. 2014 August; 34(8): 4633-4639.

Contents

MASAMICHI TOMONAGA.

Preface.

Anticancer Res. 2013 July; 33(7): 2803.

TAKURO KURITA, YUJI MAKINO.

Novel curcumin oral delivery systems.

Anticancer Res. 2013 July; 33(7): 2807-2822. Review.

NAOTO SHIRASU, SUNG OUK NAM, MASAHIDE KUROKI.

Tumor-targeted Photodynamic Therapy.

Anticancer Res. 2013 July; 33(7): 2823-2832. Review.

TOSHIYUKI TSUNODA, SENJI SHIRASAWA.

Roles of ZFAT in Haematopoiesis, Angiogenesis and Cancer Development.

Anticancer Res. 2013 July; 33(7): 2833-2838. Review.

YOSHITO AKAGI, YOSUKE ADACHI, TETSUSHI KINUGASA, YOSUKE OKA, TOMOAKI MIZOBE, KAZUO SHIROUZU.

Lymph Node Evaluation and Survival in Colorectal Cancer: Review of Population-based, Prospective Studies.

Anticancer Res. 2013 July; 33(7): 2839-2848. Review.

KAZUE NAKATA, MAI YAMAMOTO, HIROYUKI INAGAWA, GEN-ICHIRO SOMA.

Effects of Interactions between Intestinal Microbiota and Intestinal Macrophages on Health.

Anticancer Res. 2013 July; 33(7): 2849-2854. Review.

SUNG OUK NAM, FUSANORI YOTSUMOTO, KOHEI MIYATA, NAOTO SHIRASU, SHINGO MIYAMOTO, MASAHIDE KUROKI.

Possible Therapeutic Targets Among the Molecules Involved in the Warburg Effect in Tumor Cells.

Anticancer Res. 2013 July; 33(7): 2855-2860. Review.

KIWAMU TAKAHASHI, TAKEO HASEGAWA, TAKUYA ISHI, ATSUKO SUZUKI, MOTOWO NAKAJIMA, KAZUKO UNO, IUKO YASUDA, ATSUKO KISHI, KAORI SADAMOTO, FUMINORI ABE, TOHRU TANAKA.

Antitumor Effect of Combination of Hyperthermotherapy and 5-Aminolevulinic acid (ALA).

Anticancer Res. 2013 July; 33(7): 2861-2866.

TAKAHITO NISHIKATA, MAMI ISHIKAWA, TETSUHIRO MATSUYAMA, KAZUHIKO TAKAMATSU, TOSIYUKI FUKUHARA, YUTAKA KONISHI.

Primary Culture of Breast Cancer: A Model System for Epithelial-Mesenchymal Transition and Cancer Stem Cells.

Anticancer Res. 2013 July; 33(7): 2867-2874.

TAKESHI KADOWAKI, SHIHO OHNO, YOSHIE TANIGUCHI, HIROYUKI INAGAWA, CHIE KOHCHI, GEN-ICHIRO SOMA.

Induction of Nitric Oxide Production in RAW264.7 Cells under Serum-free Conditions by O-antigen Polysaccharide of Lipopolysaccharide.

Anticancer Res. 2013 July; 33(7): 2875-2880.

DAISUKE KUCHIIKE, YOSHIHIRO UTO, HIROTAKA MUKAI, NORIKO ISHIYAMA, CHIAKI ABE, DAICHI TANAKA, TOMOHITO KAWAI, KENTARO KUBO, MARTIN METTE, TOSHIO INUI, YOSHIO ENDO, HITOSHI HORI.

Degalactosylated/Desialylated Human Serum Containing GcMAF Induces Macrophage Phagocytic Activity and In Vivo Antitumor Activity.

Anticancer Res. 2013 July; 33(7): 2881-2886.

YOUSUKE OKA, YOSHITO AKAGI, TETSUSHI KINUGASA, NOBUYA ISHIBASHI, NOBUTAKA IWAKUMA, ICHITAROU SHIRATSUCHI, KAZUO SHIROUZU.

Heat-shock Pre-treatment Reduces Liver Injury and Aids Liver Recovery After Partial Hepatectomy in Mice.

Anticancer Res. 2013 July; 33(7): 2887-2894.

TERUKO HONDA, ISAMU YAMAMOTO, HIROYUKI INAGAWA.

Angiogenesis-, Metastasis- and Signaling Pathway-related Factor Dynamics in Human Colon Cancer Cells Following Interaction with Monocytes.

Anticancer Res. 2013 July; 33(7): 2895-2900.

YUKI KAWAGUCHI, ATSUSHI TABATA, HIDEAKI NAGAMUNE, KAZUTO OHKURA.

Profiles of ILY, VLY and Sm-hPAF Interaction with Human CD59.

Anticancer Res. 2013 July; 33(7): 2901-2904.

ATSUSHI TABATA, YUKIMASA OHKUBO, MASATO TAMURA, TOSHIFUMI TOMOYASU, KAZUTO OHKURA, HIDEAKI NAGAMUNE.

Construction of an Improved Drug Delivery System Tool with Enhanced Versatility in Cell-targeting.

Anticancer Res. 2013 July; 33(7): 2905-2910.

KEIJI HIROTA, YOSHINORI NAKAGAWA, RYOTA TAKEUCHI, YOSHIHIRO UTO, HITOSHI HORI, SHINYA ONIZUKA, HIROSHI TERADA.

Antitumor effect of degalactosylated gc-globulin on orthotopic grafted lung cancer in mice.

Anticancer Res. 2013 July; 33(7): 2911-2916.

TOSHIO INUI, DAISUKE KUCHIIKE, KENTARO KUBO, MARTIN METTE, YOSHIHIRO UTO, HITOSHI HORI, NORIHIRO SAKAMOTO.

Clinical Experience of Integrative Cancer Immunotherapy with GcMAF.

Anticancer Res. 2013 July; 33(7): 2917-2920.

TETSUSHI KINUGASA, YOSHITO AKAGI, TAKAFUMI OCHI, YOSHIAKI ISHIBASHI, NATSUKI TANAKA, YOUSUKE OKA, TOMOAKI MIZOBE, KOUTAROU YUGE, SHINYA FUJINO, SHIROU KIBE, KAZUO SHIROUZU.

Lateral Lymph-node Dissection for Rectal Cancer: Meta-analysis of all 944 Cases Undergoing Surgery During 1975-2004.

Anticancer Res. 2013 July; 33(7): 2921-2928.

TOMOAKI MIZOBE, YOSHITO AKAGI, HIROTO ISHIKAWA, ICHITARO SHIRATSUCHI, YOUSUKE OKA, TETSUSHI KINUGASA, KOUICHI OHSHIMA, KOZO SETOJIMA, KAZUO SHIROUZU.

Gemcitabine with Paclitaxel Therapy Against Mesocolic Leiomyosarcoma: A Case Report.

Anticancer Res. 2013 July; 33(7): 2929-2934.

TAKAFUMI OCHI, YOSHITO AKAGI, TETSUSHI KINUGASA, YOSHIAKI ISHIBASHI, NATSUKI TANAKA, SHINYA FUJINO, SHIROU KIBE, KOUTAROU YUGE, TERUO SASATOMI, TOMOAKI MIZOBE, YOUSUKE OKA, KAWANG DAE HONG, KAZUO SHIROUZU.

Virchow Lymph Node Metastatic Recurrence of Sigmoid Colon Cancer with Severe Lymph Node Metastases Successfully Treated Using Systemic Chemotherapy Combined with Radiotherapy.

Anticancer Res. 2013 July; 33(7): 2935-2940.

YUKITO GOTANDA, YOSHITO AKAGI, AKIHIKO KAWAHARA, TETSUSHI KINUGASA, TAKEFUMI YOSHIDA, YASUHIKO RYU, ICHITARO SHIRATSUCHI, MASAYOSHI KAGE, KAZUO SHIROUZU.

Expression of Monocarboxylate Transporter (MCT)-4 in Colorectal Cancer and its Role: MCT4 Contributes to the Growth of Colorectal Cancer with Vascular Endothelial Growth Factor.

Anticancer Res. 2013 July; 33(7): 2941-2948.

TAKANARU FUKUSHIMA, YOSHITO AKAGI, HIDETSUGU MURAKAMI, MASATAKA USHIJIMA, YUTAKA OGATA, KAZUO SHIROUZU, KENTA MUROTANI.

Estimation of the Number of Metastatic Lymph Nodes in Dukes' C Colorectal Cancer.

Anticancer Res. 2013 July; 33(7): 2949-2956.

MASASHI SAITO, KAZUHITO YANO, TAKASHI KAMIGAKI, SHIGENORI GOTO.

A Patient with Scirrhous Stomach Cancer Treated with Combination of Hyperthermotherapy and 5-Aminolevulinic acid (ALA).

Anticancer Res. 2013 July; 33(7): 2957-2964.

YOSHITO AKAGI, YOSUKE ADACHI, TAKAFUMI OHCHI, TETSUSHI KINUGASA, KAZUO SHIROUZU.

Prognostic Impact of Lymphatic Invasion of Colorectal Cancer: A Single-center Analysis of 1,616 Patients Over 24 Years.

Anticancer Res. 2013 July; 33(7): 2965-2970.

TAKASHI KAMIGAKI, TORU KANEKO, KEIKO NAITOH, MASASHI TAKAHARA, TAKASHIGE KONDO, HIROSHI IBE, ERIKO MATSUDA, RYUJI MAEKAWA, SHIGENORI GOTO.

Immunotherapy of Autologous Tumor Lysate-loaded Dendritic Cell Vaccines by a Closed-flow Electroporation System for Solid Tumors.

Anticancer Res. 2013 July; 33(7): 2971-2976.

DAIJIRO HIGASHI, KITARO FUTAMI, DAIBO KOJIMA, RYO FUTATSUKI, YUKIKO ISHIBASHI, TAKAFUMI MAEKAWA, YUTAKA, YANO, NORITAKA TAKATSU, FUMIHITO HIRAI, TOSHIYUKI MATSUI, AKINORI IWASHITA.

Cancer of the Small Intestine in Patients with Crohn's Disease.

Anticancer Res. 2013 July; 33(7): 2977-2980.

Contents

MASAMICHI TOMONAGA.

Preface.

Anticancer Res. 2012 June; 32(6): 2225.

MASAHIDE KUROKI, SHINGO MIYAMOTO, TAKASHI MORISAKI, FUSANORI YOTSUMOTO, NAOTO SHIRASU, YOSHIE TANIGUCHI, GEN-ICHIRO SOMA.

Biological Response Modifiers Used in Cancer Biotherapy.

Anticancer Res. 2012 June; 32(6): 2229-2233. Review.

HITOSHI HORI, YOSHIHIRO UTO, EIJI NAKATA.

Boron Tracedrugs Challenge for Neutron Dynamic Therapy.

Anticancer Res. 2012 June; 32(6): 2235-2239. Review.

TAKASHI MORISAKI, HIDEYA ONISHI, MITSUO KATANO.

Cancer Immunotherapy Using NKG2D and DNAM-1 Systems.

Anticancer Res. 2012 June; 32(6): 2241-2247. Review.

TAKASHI MORISAKI, MASAYO UMEBAYASHI, AKIFUMI KIYOTA, NORIHIRO KOYA, HIROTO TANAKA, HIDEYA ONISHI, MITSUO KATANO.

Combining Cetuximab with Killer Lymphocytes Synergistically Inhibits Human Cholangiocarcinoma Cells In Vitro.

Anticancer Res. 2012 June; 32(6): 2249-2256.

TAKESHI KADOWAKI, MISATO SHIMADA, HIROYUKI INAGAWA, CHIE KOHCHI, MITSUOMI HIRASHIMA, GEN-ICHIRO SOMA.

Reconsideration of Macrophage and Dendritic Cell Classification.

Anticancer Res. 2012 June; 32(6): 2257-2261. Short Review.

SATOSHI OHNO, RYUJI OKUYAMA, ATSUSHI ARUGA, HARUO SUGIYAMA, MASAKAZU YAMAMOTO.

Phase I Trial of Wilms' Tumor 1 (WT1) Peptide Vaccine with GM-CSF or CpG in Patients with Solid Malignancy.

Anticancer Res. 2012 June; 32(6): 2263-2269.

TAKEHARU OTA, KEIKO DOI, TAKAHIRO FUJIMOTO, YOKO TANAKA, MASAHIRO OGAWA, HIROSHI MATSUZAKI, MASAHIDE KUROKI, SHINGO MIYAMOTO, SENJI SHIRASAWA, TOSHIYUKI TSUNODA.

KRAS Up-regulates the Expression of miR-181a, miR-200c and miR-210 in a Three-dimensional-specific Manner in DLD-1 Colorectal Cancer Cells.

Anticancer Res. 2012 June; 32(6): 2271-2275.

YOSHITO AKAGI, TETSUSHI KINUGASA, TOMOAKI MIZOBE, AKIHIKO KAWAHARA, MASAYOSHI KAGE, KAZUO SHIROUZU.

Expression of Dihydropyrimidine Dehydrogenase, Orotate Phosphoribosyl Transferase and Thymidylate Synthase in Patients with Primary Colorectal Cancer, and Associations with Site of First Metastasis.

Anticancer Res. 2012 June; 32(6): 2277-2282.

KIYOKO KATO.

Endometrial Cancer Stem Cells: A New Target for Cancer Therapy.

Anticancer Res. 2012 June; 32(6): 2283-2293. Review.

YASUHIRO KURAMITSU, YUFENG WANG, KUMIKO TABA, SHIGEYUKI SUENAGA, SHOMEI RYOZAWA, SEIJI KAINO, ISAO SAKAIDA, KAZUYUKI NAKAMURA.

Heat-shock Protein 27 Plays the Key Role in Gemcitabine-resistance of Pancreatic Cancer Cells.

Anticancer Res. 2012 June; 32(6): 2295-2299. Review.

YASUHIRO YOSHIDA, TOSHIYUKI TSUNODA, KEIKO DOI, TAKAHIRO FUJIMOTO, YOKO TANAKA, TAKEHARU OTA, MASAHIRO OGAWA, HIROSHI MATSUZAKI, MASAHIDE KUROKI, AKINORI IWASAKI, SENJI SHIRASAWA.

ALPK2 is Crucial for Luminal Apoptosis and DNA Repair-related Gene Expression in a Three-dimensional Colonic-crypt Model.

Anticancer Res. 2012 June; 32(6): 2301-2308.

TETSUSHI KINUGASA, YOSHITO AKAGI, TAKAFUMI OCHI, NATSUKI TANAKA, AKIHIKO KAWAHARA, YOSHINOBU ISHIBASHI, YUKITO GOTANDA, KEIZO YAMAGUCHI, ICHITAROU SHIRATSUCHI, YOUSUKE OKA, MASAYOSHI KAGE, KAZUO SHIROUZU.

Increased Claudin-1 Protein Expression in Hepatic Metastatic Lesions of Colorectal Cancer.

Anticancer Res. 2012 June; 32(6): 2309-2314.

TAKAFUMI OCHI, YOSHITO AKAGI, TETSUSHI KINUGASA, TATSUYUKI KAKUMA, AKIHIRO KAWAHARA, TERUO SASATOMI, YUKITO GOTANDA, KEIZO YAMAGUCHI, NATSUKI TANAKA, YOSHIAKI ISHIBASHI, SHINGO MIYAMOTO, MASAYOSHI KAGE, KAZUO SHIROUZU.

Amphiregulin Is a Prognostic Factor in Colorectal Cancer.

Anticancer Res. 2012 June; 32(6): 2315-2321.

ATSUSHI TABATA, YUKIMASA OHKUBO, ERIKO SAKAKURA, TOSHIFUMI TOMOYASU, KAZUTO OHKURA, HIDEAKI NAGAMUNE.

Investigation of a Bacterial Pore-forming Chimera Toxin for Application as a Novel Drug-delivery System Tool.

Anticancer Res. 2012 June; 32(6): 2323-2329.

MAKOTO KUBO, HIDEYA ONISHI, SYOJI KUROKI, MASAYUKI OKIDO, KAZUO SHIMADA, KAZUNORI YOKOHATA, SHUYO UMEDA, TAKAHIRO OGAWA, MASAO TANAKA, MITSUO KATANO.

Short-term and Low-dose Prednisolone Administration Reduces Aromatase Inhibitor-induced Arthralgia in Patients with Breast Cancer.

Anticancer Res. 2012 June; 32(6): 2331-2336.

MISATO SHIMADA, TAKESHI KADOWAKI, YOSHIE TANIGUSHI, HIROYUKI INAGAWA, KATHUICHIRO OKAZAKI, GEN-ICHIRO SOMA.

The Involvement of O-Antigen Polysaccharide in Lipopolysaccharide in Macrophage Activation.

Anticancer Res. 2012 June; 32(6): 2237-2341. Short Review.

KAZUTO OHKURA, YUKI KAWAGUCHI, ATSUSHI TABATA, ATSUSHI YAMAMOTO, YASUO SHINOHARA, HIDEAKI NAGAMUNE, HITOSHI HORI.

Molecular Profiles of Cholesterol-dependent Cytolysin Family-derived 11mer Regions.

Anticancer Res. 2012 June; 32(6): 2343-2346.

KOHEI MIYATA, FUSANORI YOTSUMOTO, SUNG OUK NAM, MASAHIDE KUROKI, SHINGO MIYAMOTO.

Regulatory Mechanisms of the HB-EGF Autocrine Loop in Inflammation, Homeostasis, Development and Cancer.

Anticancer Res. 2012 June; 32(6): 2347-2352. Review.

TAEKO UEDA, MIYAKO MAEHARA, NAOMI NAKAYAMA, HARUHIKO KONDO, KYOKO SHIROTA, TOSHIYUKI YOSHIZATO, SHINGO MIYAMOTO.

Clinical Significance of Cell-free and Concentrated Ascites Re-infusion Therapy for Advanced and Recurrent Gynecological Cancer.

Anticancer Res. 2012 June; 32(6): 2353-2357.

YOSHIHIRO UTO, SYOTA YAMAMOTO, HIROTAKA MUKAI, NORIKO ISHIYAMA, RYOTA TAKEUCHI, YOSHINORI NAKAGAWA, KEIJI HIROTA, HIROSHI TERADA, SHINYA ONIZUKA, HITOSHI HORI.

β-Galactosidase Treatment Is a Common First-stage Modification of the Three Major Subtypes of Gc Protein to GcMAF.

Anticancer Res. 2012 June; 32(6): 2359-2364.

DAIJIRO HIGASHI, KATSUNORI SEKI, YUKIKO ISHIBASHI, YUJI EGAWA, MASAKAZU KOGA, TAKAHIDE SASAKI, KIMIKAZU HIRANO, KOJI MIKAMI, KITARO FUTAMI, TAKAFUMI MAEKAWA, MAKI SUDO.

The Effect of Lentinan Combination Therapy for Unresectable Advanced Gastric Cancer.

Anticancer Res. 2012 June; 32(6): 2365-2368.

KATSUHIKO SUZUKI, SATOSHI OHNO, YOKO SUZUKI, YUMIKO OHNO, RYUJI OKUYAMA, ATSUSHI ARUGA, MASAKAZU YAMAMOTO, KEN-O ISHIHARA, TSUTOMU NOZAKI, SHIGEKI MIURA, HIROSHI YOSHIOKA, YUICHI MORI.

Effect of Green Tea Extract on Reactive Oxygen Species Produced by Neutrophils from Cancer Patients.

Anticancer Res. 2012 June; 32(6): 2369-2375.

NAOTO SHIRASU, MASAHIDE KUROKI.

Functional Design of Chimeric T-Cell Antigen Receptors for Adoptive Immunotherapy of Cancer: Architecture and Outcomes.

Anticancer Res. 2012 June; 32(6): 2377-2383. Review.

HIDEYA ONISHI, NORIHIRO KOYA, AKIFUMI KIYOTA, HIROTO TANAKA, MASAYO UMEBAYASHI, MITSUO KATANO, TAKASHI MORISAKI.

A New Method for Rapid Cytotoxic T-lymphocyte Induction Using a Multiple Cytokine Cocktail.

Anticancer Res. 2012 June; 32(6): 2385-2390. 

Contents

MASAMICHI TOMONAGA.

Anticancer Res. 2011 July; 31(7): 2409. Preface.

TAKAHIRO FUJIMOTO, SENJI SHIRASAWA.

KRAS-Induced Actin-interacting Protein: A Potent Target for Obesity, Diabetes and Cancer.

Anticancer Res. 2011 July; 31(7): 2413-2417. Review.

AKIO YAMASAKI, HIDEYA ONISHI, TAKASHI MORISAKI, MITSUO KATANO.

Induction of Cytotoxic T Lymphocytes by CEA Peptide-pulsed γδ T-Cells Isolated from Patients with Advanced Cancer.

Anticancer Res. 2011 July; 31(7): 2419-2424.

HIROTOMO SHIBAGUCHI, HIROFUMI TSURU, MOTOMU KUROKI, MASAHIDE KUROKI.

Sonodynamic Cancer Therapy: A Non-invasive and Repeatable Approach Using Low-intensity Ultrasound with a Sonosensitizer.

Anticancer Res. 2011 July; 31(7): 2425-2429. Review.

HIROYUKI INAGAWA, CHIE KOHCHI, GEN-ICHIRO SOMA.

Oral Administration of Lipopolysaccharides for the Prevention of Various Diseases: Benefit and Usefulness.

Anticancer Res. 2011 July; 31(7): 2431-2436. Short Review.

KAZUE NAKATA, HIROYUKI INAGAWA, GEN-ICHIRO SOMA.

Lipopolysaccharide IP-PA1 from Pantoea agglomerans Prevents Suppression of Macrophage Function in Stress-induced Diseases.

Anticancer Res. 2011 July; 31(7): 2437-2440. Short Review.

SATOSHI DOHI, SATOSHI OHNO, YUMIKO OHNO, MASAHIRO TAKAKURA, SATORU KYO, GEN-ICHIRO SOMA, HARUO SUGIYAMA, MASAKI INOUE.

WT1 Peptide Vaccine Stabilized Intractable Ovarian Cancer Patient for One Year: A Case Report.

Anticancer Res. 2011 July; 31(7): 2441-2445.

SATOSHI OHNO, FUMIHIDE TAKANO, YASUYUKI OHTA, SATORU KYO, SUBARU MYOJYO, SATOSHI DOHI, HARUO SUGIYAMA, TOMIHISA OHTA, MASAKI INOUE.

Frequency of Myeloid Dendritic Cells Can Predict the Efficacy of Wilms' Tumor 1 Peptide Vaccination.

Anticancer Res. 2011 July; 31(7): 2447-2452.

TOSHIYUKI TSUNODA, YASUO TAKASHIMA, YASUHIRO YOSHIDA, KEIKO DOI, YOKO TANAKA, TAKAHIRO FUJIMOTO, TAKASHI MACHIDA, TAKEHARU OTA, MIDORI KOYANAGI, MASAHIDE KUROKI, TAKEHIKO SASAZUKI, SENJI SHIRASAWA.

Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells.

Anticancer Res. 2011 July; 31(7): 2453-2459.

HIROSHI TSUJIOKA, TATSUYA FUKAMI, FUSANORI YOTSUMOTO, TAEKO UEDA, SHOKO HIKITA, YOKO TAKAHASHI, HARUHIKO KONDO, MASAHIDE KUROKI, SHINGO MIYAMOTO.

A Possible Clinical Adaptation of CRM197 in Combination with Conventional Chemotherapeutic Agents for Ovarian Cancer.

Anticancer Res. 2011 July; 31(7): 2461-2465.

TAKESHI KADOWAKI, HIROYUKI INAGAWA, CHIE KOHCHI, MITSUOMI HIRASHIMA, GEN-ICHIRO SOMA.

Functional Characterization of Lipopolysaccharide derived from Symbiotic Bacteria in Rice as a Macrophage-activating Substance.

Anticancer Res. 2011 July; 31(7): 2467-2476.

EIJI NAKATA, MASATO KOIZUMI, YOHEI YAMASHITA, KENTA ONAKA, YOSHINORI SAKURAI, NATSUKO KONDO, KOJI ONO, YOSHIHIRO UTO, HITOSHI HORI.

Design, Synthesis, and Destructive Dynamic Effects of BODIPY-containing and Curcuminoid Boron Tracedrugs for Neutron Dynamic Therapy.

Anticancer Res. 2011 July; 31(7): 2477-2481.

NAOKO KUNAMI, FUSANORI YOTSUMOTO, KENJI ISHITSUKA, TATSUYA FUKAMI, TAKASHI ODAWARA, SADAO MANABE, TOYOKAZU ISHIKAWA, KAZUO TAMURA, MASAHIDE KUROKI, SHINGO MIYAMOTO.

Antitumor Effects of CRM197, A Specific Inhibitor of HB-EGF, in T-Cell Acute Lymphoblastic Leukemia.

Anticancer Res. 2011 July; 31(7):2483-2488 .

YOSHIHIRO UTO, SYOTA YAMAMOTO, RYOTA TAKEUCHI, YOSHINORI NAKAGAWA, KEIJI HIROTA, HIROSHI TERADA, SHINYA ONIZUKA, EIJI NAKATA, HITOSHI HORI.

Effect of the Gc-derived Macrophage-activating Factor Precursor (preGcMAF) on Phagocytic Activation of Mouse Peritoneal Macrophages.

Anticancer Res. 2011 July; 31(7): 2489-2492.

TERUKO HONDA, HIROYUKI INAGAWA, ISAMU YAMAMOTO.

Differential Expression of mRNA in Human Monocytes following Interaction with Human Colon Cancer Cells.

Anticancer Res. 2011 July; 31(7): 2493-2497.

DAIJIRO HIGASHI, KITARO FUTAMI, YUKIKO ISHIBASHI, YUJI EGAWA, TAKAFUMI MAEKAWA, TOSHIYUKI MATSUI, AKINORI IWASHITA, MASAHIDE KUROKI.

Clinical Course of Colorectal Cancer in Patients with Ulcerative Colitis.

Anticancer Res. 2011 July; 31(7): 2499-2504.

TAKASHI MORISAKI, HIDEYA ONISHI, NORIHIRO KOYA, AKIFUMI KIYOTA, HIROTO TANAKA, MASAYO UMEBAYASHI, TOSHITATSU OGINO, IORI NAGAMATSU, MITSUO KATANO.

Combinatorial Cytotoxicity of Gemcitabine and Cytokine-activated Killer Cells in Hepatocellular Carcinoma via the NKG2D-MICA/B System.

Anticancer Res. 2011 July; 31(7): 2505-2510.

HIDECHIKA OKADA, MASAKI IMAI, FUMIKO ONO, ALAN OKADA, TOYOHIRO TADA, YUKA MIZUE, KEIJI TERAO, NORIKO OKADA.

Novel Complementary Peptide to Target Molecules.

Anticancer Res. 2011 July; 31(7): 2511-2516.

TAKEFUMI YOSHIDA, TETSUSHI KINUGASA, YOSHITO AKAGI, AKIHIKO KAWAHARA, KANSAKAR ROMEO, ICHITAROU SHIRATSUCHI, YASUHIKO RYU, YUKITO GOTANDA, KAZUO SHIROUZU.

Decreased Expression of Claudin-1 in Rectal Cancer: A Factor for Recurrence and Poor Prognosis.

Anticancer Res. 2011 July; 31(7):2517-2525 .

TADAHIRO OHMURA, TAKEO FUKUSHIMA, HIROTOMO SHIBAGUCHI, SHIN YOSHIZAWA, TOORU INOUE, MASAHIDE KUROKI, KAZUNARI SASAKI, SHIN-ICHIRO UMEMURA.

Sonodynamic Therapy with 5-Aminolevulinic Acid and Focused Ultrasound for Deep-seated Intracranial Glioma in Rat.

Anticancer Res. 2011 July; 31(7):2527-2533 .

YASUHIRO YOSHIDA, TOSHIYUKI TSUNODA, KEIKO DOI, YOKO TANAKA, TAKAHIRO FUJIMOTO, TAKASHI MACHIDA, TAKEHARU OTA, MIDORI KOYANAGI, YASUO TAKASHIMA, TAKEHIKO SASAZUKI, MASAHIDE KUROKI, AKINORI IWASAKI, SENJI SHIRASAWA.

KRAS-mediated Up-regulation of RRM2 Expression Is Essential for the Proliferation of Colorectal Cancer Cell Lines.

Anticancer Res. 2011 July; 31(7):2535-2539 .

ICHITAROU SHIRATSUCHI, YOSHITO AKAGI, AKIHIKO KAWAHARA, TETSUSHI KINUGASA, KANSAKAR ROMEO, TAKEFUMI YOSHIDA, YASUHIKO RYU, YUKITO GOTANDA, MASAYOSHI KAGE, KAZUO SHIROUZU.

Expression of IGF-1 and IGF-1R and Their Relation to Clinicopathological Factors in Colorectal Cancer.

Anticancer Res. 2011 July; 31(7):2541-2545 .

TETSUSHI KINUGASA, YOSHITO AKAGI, KENTA MUROTANI, KANSAKAR ROMEO, TAKEFUMI YOSHIDA, YASUHIKO RYU, ICHITAROU SHIRATSUCHI, KAZUO SHIROUZU.

Relationship between Ulcerative Colitis Patients Treated with Leukocytapheresis and Ulcerative Colitis-associated Colorectal Cancer.

Anticancer Res. 2011 July; 31(7):2547-2552 .

SHOKO HIKITA, FUSANORI YOTSUMOTO, TATSUYA FUKAMI, SHINJI HORIUCHI, AYAKO SANUI, KOHEI MIYATA, SUNG OUK NAM, HIROSHI TSUJIOKA, TAEKO UEDA, KYOKO SHIROTA, TOSHIYUKI YOSHIZATO, KAZUHIRO MAEDA, TOYOKAZU ISHIKAWA, YOSHINOBU OKUNO, MASAHIDE KUROKI, EISUKE MEKADA, SHINGO MIYAMOTO.

Assessment of HB-EGF Levels in Peritoneal Fluid and Serum of Ovarian Cancer Patients using ELISA.

Anticancer Res. 2011 July; 31(7):2553-2559 .

KAZUTO OHKURA, YASUO SHINOHARA, HITOSHI HORI.

Efficiency of Antimicrobial Defense: Molecular Flexibility of Natural Defensin and Artificial Bis-quaternary Ammonium Compound.

Anticancer Res. 2011 July; 31(7):2561-2564 . 

Contents

HIROSHI TSUJIOKA, FUSANORI YOTSUMOTO, KYOKO SHIROTA, SHINJI HORIUCHI, TOSHIYUKI YOSHIZATO, MASAHIDE KUROKI, SHINGO MIYAMOTO.

Emerging Strategies for ErbB Ligand-based Targeted Therapy for Cancer .

Anticancer Res. 2010 August; 30(8): 3107-3112. Review.

TAKEHISA HEBISHIMA, YASUNOBU MATSUMOTO, GEN WATANABE, GEN-ICHIRO SOMA, CHIE KOHCHI, KAZUYOSHI TAYA, YOSHIHIRO HAYASHI, YOSHIKAZU HIROTA.

Recovery from Immunosuppression-related Disorders in Humans and Animals by IP-PA1, An Edible Lipopolysaccharide.

Anticancer Res. 2010 August; 30(8): 3113-3118. Review.

HIROSHI TSUJIOKA, TORU HACHISUGA, SHOKO HIKITA, TAEKO UEDA, FUSANORI YOTSUMOTO, KYOKO SHIROTA, TOSHIYUKI YOSHIZATO, TATSUHIKO KAWARABAYASHI, MASAHIDE KUROKI, SHINGO MIYAMOTO.

Apoptosis as a Possible Candidate Mechanism for Removal of Tamoxifen-related Endometrial Cells with KRAS Mutations.

Anticancer Res. 2010 August; 30(8): 3119-3123.

MIKIO KATO, SHIGENORI GOTO, GEN-ICHIRO SOMA.

Lymphokine-activated Killer Cell Therapy Combined with High-dose Glucocorticoid Showed Clinical Efficacy towards Advanced Lung Carcinoma.

Anticancer Res. 2010 August; 30(8): 3125-3128.

KEIJI HIROTA, YUSUKE OISHI, HIROAKI TANIGUCHI, KEIICHI SAWACHI, HIROYUKI INAGAWA, CHIE KOHCHI, GEN-ICHIRO SOMA, HIROSHI TERADA.

Antitumor Effect of Inhalatory Lipopolysaccharide and Synergetic Effect in Combination with Cyclophosphamide.

Anticancer Res. 2010 August; 30(8): 3129-3134.

KEIICHI SAWACHI, YASUTERU SHIMADA, HIROAKI TANIGUCHI, KEIJI HIROTA, HIROYUKI INAGAWA, CHIE KOHCHI, GEN-ICHIRO SOMA, KIMIKO MAKINO, HIROSHI TERADA.

Cytotoxic Effects of Activated Alveolar Macrophages on Lung Carcinoma Cells via Cell-to-Cell Contact and Nitric Oxide.

Anticancer Res. 2010 August; 30(8): 3135-3141.

AYAKO SANUI, FUSANORI YOTSUMOTO, HIROSHI TSUJIOKA, TATSUYA FUKAMI, SHINJI HORIUCHI, KYOKO SHIROTA, TOSHIYUKI YOSHIZATO, TATSUHIKO KAWARABAYASHI, MASAHIDE KUROKI, SHINGO MIYAMOTO.

HB-EGF Inhibition in Combination with Various Anticancer Agents Enhances its Antitumor Effects in Gastric Cancer?.

Anticancer Res. 2010 August; 30(8): 3143-3149.

TAKESHI KADOWAKI, HIROYUKI INAGAWA, CHIE KOHCHI, MITSUOMI HIRASHIMA, GEN-ICHIRO SOMA.

Preparation of Lipopolysaccharide Derived from Pantoea agglomerans Labeled with Fluorescence as a Tracer for Kinetics Analysis.

Anticancer Res. 2010 August; 30(8): 3151-3157.

HIROAKI TANIGUCHI, YASUTERU SHIMADA, KEIICHI SAWACHI, KEIJI HIROTA, HIROYUKI INAGAWA, CHIE KOHCHI, GEN-ICHIRO SOMA, KIMIKO MAKINO, HIROSHI TERADA.

Lipopolysaccharide-activated Alveolar Macrophages Having Cytotoxicity toward Lung Tumor Cells through Cell-to-Cell Binding-dependent Mechanism.

Anticancer Res. 2010 August; 30(8): 3159-3165.

GOSHI NAGAO, KAZUO ISHII, KEIJI HIROTA, KIMIKO MAKINO, HIROSHI TERADA.

Role of Lipid Rafts in Phagocytic Uptake of Polystyrene Latex Microspheres by Macrophages.

Anticancer Res. 2010 August; 30(8): 3167-3176.

KAZUTO OHKURA, KATSUMI FUKINO, YASUO SHINOHARA, HITOSHI HORI.

N-Acetyl Transferase 2 Polymorphisms Associated with Isoniazid Pharmacodynamics: Molecular Features for Ligand Interaction.

Anticancer Res. 2010 August; 30(8): 3177-3180.

TETSUSHI KINUGASA, YOSHITO AKAGI, TAKEFUMI YOSHIDA, YASUHIKO RYU, ICHITAROU SHIRATUCHI, NOBUYA ISHIBASHI, KAZUO SHIROUZU.

Increased Claudin-1 Protein Expression Contributes to Tumorigenesis in Ulcerative Colitis-associated Colorectal Cancer.

Anticancer Res. 2010 August; 30(8): 3181-3186.

SATOSHI DOHI, SATOSHI OHNO, YUMIKO OHNO, SATORU KYO, GEN-ICHIRO SOMA, HARUO SUGIYAMA, MASAKI INOUE.

WT1 Expression Correlates with Angiogenesis in Endometrial Cancer Tissue.

Anticancer Res. 2010 August; 30(8): 3187-3192.

DAIJIRO HIGASHI, YUKIKO ISHIBASHI, TOMOAKI TAMURA, KAORI NII, YUJI EGAWA, MASAKAZU KOGA, TAKASHIGE TOMIYASU, TAKANORI HARIMURA, RYOSUKE TANAKA, RYO FUTATSUKI, SIMPEI NODA, KITARO FUTAMI, TAKAFUMI MAEKAWA, YASUHIRO TAKAKI, FUMIHITO HIRAI, TOSHIYUKI MATSUI.

Clinical Features of and Chemotherapy for Cancer of the Small Intestine.

Anticancer Res. 2010 August; 30(8): 3193-3197.

RYOTA TAKEUCHI, YOSHIHIRO UTO, YOSHINORI NAKAGAWA, KEIJI HIROTA, HIROSHI TERADA, HITOSHI HORI.

A Retrospective Study of a Calcium Agent (E-Ca) Using Data on Bone Mineral Density Obtained by DXA Method.

Anticancer Res. 2010 August; 30(8): 3199-3205.

TERUKO HONDA, HIROYUKI INAGAWA, TAKASHI NISHIZAWA, HIROSHI YOSHIMURA, ISAMU YAMAMOTO, GEN-ICHIRO SOMA.

The Relationship between Clinicopathological Factors and the Reduction of Pyrimidine Nucleoside Phosphorylase Activity after Preoperative Administration of 5′-Deoxy-5-fluorouridine.

Anticancer Res. 2010 August; 30(8): 3207-3211.

Contents

Fukushima T, Takeshima H, Kataoka H.

Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT.

Anticancer Res. 2009 Nov; 29 (11): 4845-54. Review.

Taniguchi Y, Yoshioka N, Nakata K, Nishizawa T, Inagawa H, Kohchi C, Soma G.

Mechanism for maintaining homeostasis in the immune system of the intestine.

Anticancer Res. 2009 Nov; 29 (11): 4855-60. Review.

Yoshioka N, Taniguchi Y, Yoshida A, Nakata K, Nishizawa T, Inagawa H, Kohchi C, Soma G.

Intestinal macrophages involved in the homeostasis of the intestine have the potential for responding to LPS.

Anticancer Res. 2009 Nov; 29 (11): 4861-65. Review.

Yoshida A, Kohchi C, Inagawa H, Nishizawa T, Soma G.

Improvement of allergic dermatitis via regulation of the Th1/Th2 immune system balance by macrophages activated with lipopolysaccharide derived from Pantoea agglomerans (IP-PA1).

Anticancer Res. 2009 Nov; 29 (11): 4866-70. Review.

Kadowaki T, Yasui Y, Takahashi Y, Kohchi C, Soma G, Inagawa H.

Comparative immunological analysis of innate immunity activation after oral administration of wheat fermented extract to teleost fish.

Anticancer Res. 2009 Nov; 29 (11): 4871-77.

Yotsumoto F, Sanui A, Fukami T, Shirota K, Horiuchi S, Tsujioka H, Yoshizato T, Kuroki Ma, Miyamoto S.

Efficacy of ligand-based targeting for the EGF system in cancer.

Anticancer Res. 2009 Nov; 29 (11): 4879-85. Review.

Dohi S, Ohno S, Ohno Y, Soma G, Kyo S, Inoue M.

Correlation between WT1 expression and cell proliferation in endometrial cancer.

Anticancer Res. 2009 Nov; 29 (11): 4887-91.

Higashi D, Watanabe Y, Hirano K, Shimomura T, Egawa Y, Tomiyasu T, Ishibashi Y, Futami K, Maekawa T, Ota A, Oshige K, Iwashita A.

A study of the postoperative course in cases of GIST of the stomach. The efficacy of imatinib in cases of recurrence.

Anticancer Res. 2009 Nov; 29 (11): 4893-96.

Ohkura K, Hori H, Shinohara Y.

RRole of C-terminal region of yeast ADP/ATP carrier 2 protein: dynamics of flexible C-terminal arm.

Anticancer Res. 2009 Nov; 29 (11): 4897-4900.

Contents

Koga F, Kihara K, Neckers L.

Inhibition of cancer invasion and metastasis by targeting the molecular chaperone heat-shock protein 90.

Anticancer Res. 2009 Mar; 29 (3): 797-807. Review.

Ohno S, Ohno Y, Suzuki N, Soma G, Inoue M.

High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with advanced cancer.

Anticancer Res. 2009 Mar; 29 (3): 809-15. Review.

Kohchi C, Inagawa H, Nishizawa T, Soma G.

ROS and innate immunity.

Anticancer Res. 2009 Mar; 29 (3): 817-21. Review.

Miyamoto S, Fukami T, Yagi H, Kuroki Ma, Yotsumoto F.

Potential for Molecularly Targeted Therapy against Epidermal Growth Factor Receptor Ligands.

Anticancer Res. 2009 Mar;29 (3): 823-30. Review.

Nakamura M, Wada J, Suzuki H, Tanaka M, Katano M, Morisaki T.

Long-term Outcome of Immunotherapy for Patients with Refractory Pancreatic Cancer.

Anticancer Res. 2009 Mar; 29 (3): 831-6.

Taira Z, Monmasu H, Ueda Y.

Innate Host-defensive Function of a Hepatic Lipid Fraction Produced in Low-dose Carbon Tetrachloride-pretreated Mice.

Anticancer Res. 2009 Mar; 29 (3): 837-41.

Yamasaki A, Shoda M, Iijima H, Nagai S, Wada J, Suzuki H, Chikazawa N, Tasaka T, Kameda C, Tanaka H, Ikebe M, Jo E, Sato N, Nakamura M, Sekine F, Morisaki T, Katano M.

A Protein-bound Polysaccharide, PSK, Enhances Tumor Suppression Induced by Docetaxel in a Gastric Cancer Xenograft Model.

Anticancer Res. 2009 Mar; 29 (3): 843-50.

Huo Q, Kinugasa T, Wang L, Huang J, Zhao J, Shibaguchi H, Kuroki Mo, Tanaka T, Yamashita Y, Nabeshima K, Iwasaki H, Kuroki Ma.

Claudin-1 Protein is a Major Factor Involved in the Tumorigenesis of Colorectal Cancer

Anticancer Res. 2009 Mar; 29 (3): 851-7.

Taniguchi Y, Yoshioka N, Nishizawa T, Inagawa H, Kohchi C, Soma G.

Utility and Safety of LPS-based Fermented Flour Extract as a Macrophage Activator.

Anticancer Res. 2009 Mar; 29 (3): 859-64. Review.

Yoshioka N, Taniguchi Y, Yoshida A, Nakata K, Nishizawa T, Inagawa H, Kohchi C, Soma G.

Intracellular Localization of CD14 Protein in Intestinal Macrophages.

Anticancer Res. 2009 Mar; 29 (3): 865-9.

Kameda C, Tanaka H, Yamasaki A, Nakamura M, Koga K, Sato N, Kubo M, Kuroki S, Tanaka M, Katano M

The Hedgehog Pathway Is a Possible Therapeutic Target for Patients with Estrogen Receptor-negative Breast Cancer.

Anticancer Res. 2009 Mar; 29 (3): 871-9.

Wada J, Suzuki H, Fuchino R, Yamasaki A, Nagai S, Yanai K, Koga K, Nakamura M, Tanaka M, Morisaki T, Katano M.

The Contribution of Vascular Endothelial Growth Factor to the Induction of Regulatory T-Cells in Malignant Effusions.

Anticancer Res. 2009 Mar; 29 (3): 881-8.

Yoshino S, Fukushima T, Hayashi S, Nonaka M, Ogawa K, Sasaki K, Umemura S.

Effects of Focused Ultrasound Sonodynamic Treatment on the Rat Blood-Brain Barrier

Anticancer Res. 2009 Mar; 29 (3): 889-95.

Hayashi S, Yamamoto M, Tachibana K, Ueno Y, Bu G, Fukushima T.

Mechanism of Photofrin-enhanced Ultrasound-induced Human Glioma Cell Death.

Anticancer Res. 2009 Mar; 29 (3): 897-905.

Yoshida A, Inagawa H, Kohchi C, Nishizawa T, Soma G.

The role of toll-like receptor 2 in survival strategies of Mycobacterium tuberculosis in macrophage phagosomes.

Anticancer Res. 2009 Mar; 29 (3): 907-10. Review.

Oshiro S, Tsugu H, Komatsu F, Ohmura T, Ohta M, Sakamoto S, Fukushima T, Inoue T.

Efficacy of temozolomide treatment in patients with high-grade glioma.

Anticancer Res. 2009 Mar; 29 (3): 911-7.

Tsugu H, Oshiro S, Yanai F, Komatsu F, Abe H, Fukushima T, Nomura Y, Matsumoto S, Nabeshima K, Takano K, Utsunomiya H.

Management of pilomyxoid astrocytomas: our experience.

Anticancer Res. 2009 Mar; 29 (3): 919-26.

Higashi D, Futami K, Egawa Y, Hirano K, Tomiyasu T, Ishibashi Y, Simomura T, Nii K, Kuroki H, Maekawa T, Ono Y, Matsui T

Infliximab treatment for anal fistula in patients with Crohn's disease.

Anticancer Res. 2009 Mar; 29 (3): 927-33.

Ohkura K, Kawaguchi Y, Watanabe Y, Masubuchi Y, Shinohara Y, Hori H.

Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket.

Anticancer Res. 2009 Mar; 29 (3): 935-42.

Nonaka M, Yamamoto M, Yoshino S, Umemura S, Sasaki K, Fukushima T.

Sonodynamic therapy consisting of focused ultrasound and a photosensitizer causes a selective antitumor effect in a rat intracranial glioma model.

Anticancer Res. 2009 Mar; 29 (3): 943-50. 

Contents

Kuroki Ma, Hachimine K, Abe H, Shibaguchi H, Kuroki Mo, Maekawa S, Yanagisawa J, Kinugasa T, Tanaka T, Yamashita Y.

Sonodynamic therapy of cancer using novel sonosensitizers.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3673-7. Review.

Tanaka T, Kuroki Mo, Hamada H, Kato K, Kinugasa T, Shibaguchi H, Zhao J, Kuroki Ma.

Cancer-targeting gene therapy using tropism-modified adenovirus.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3679-84. Review.

Fukushima T, Kataoka H.

Roles of insulin-like growth factor binding protein-2 (IGFBP-2) in glioblastoma.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3685-92. Review.

Ohkura K, Uto Y, Nagasawa H, Hori H.

Effect of molecular chirality and side chain bulkiness on angiogenesis of haloacetylcarbamoyl-2-nitroimidazole compounds.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3693-700.

Taniguchi Y, Nishizawa T, Honda T, Yoshioka N, Inagawa H, Kohchi C, Soma G.

Development and potential use of a monoclonal antibody to the lipopolysaccharide of Pantoea agglomerans (IP-PA1).

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3701-6.

Yoshida A, Inagawa H, Kohchi C, Nishizawa T, Hori H, Soma G.

Development of a drug delivery system using a model that mimics chronic infection of Mycobacterium bovis Calmette-Guerin in alveolar macrophages.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3707-11. Review.

Miyamoto S, Yagi H, Yotsumoto F, Horiuchi S, Yoshizato T, Kawarabayashi T, Kuroki Ma, Mekada E

New approach to cancer therapy: heparin binding-epidermal growth factor-like growth factor as a novel targeting molecule.

Anticancer Res. 2007 Nov-Dec;27 (6A): 3713-21. Review.

Nakata K, Inagawa H, Nishizawa T, Kohchi C, Soma G.

Suppression of response to foreign substances by intestinal macrophages.

Anticancer Res. 2007 Nov-Dec;27 (6A):3723-7. Review.

Kinugasa T, Huo Q, Higashi D, Shibaguchi H, Kuroki Mo, Tanaka T, Futami K, Yamashita Y, Hachimine K, Maekawa S, Nabeshima K, Iwasaki H, Kuroki Ma.

Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3729-34.

Maekawa S, Iwasaki A, Shirakusa T, Enatsu S, Kawakami T, Kuroki Mo, Kuroki Ma.

Correlation between lymph node metastasis and the expression of VEGF-C, VEGF-D and VEGFR-3 in T1 lung adenocarcinoma.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3735-41.

Nakamura M, Kubo M, Yanai K, Mikami Y, Ikebe M, Nagai S, Yamaguchi K, Tanaka M, Katano M.

Anti-patched-1 antibodies suppress hedgehog signaling pathway and pancreatic cancer proliferation.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3743-7.

Mitsuyama K, Matsumoto S, Masuda J, Yamasakii H, Kuwaki K, Takedatsu H, Sata M.

Therapeutic strategies for targeting the IL-6/STAT3 cytokine signaling pathway in inflammatory bowel disease.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3749-56.

Oshiro S, Tsugu H, Komatsu F, Abe H, Onishi H, Ohmura T, Iwaasa M, Sakamoto S, Fukushima T.

Quantitative assessment of gliomas by proton magnetic resonance spectroscopy.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3757-63.

Ohno S, Ohno Y, Suzuki N, Soma G, Inoue M.

Cyclooxygenase-2 expression correlates with apoptosis and angiogenesis in endometrial cancer tissue.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3765-70.

Higashi D, Futami K, Kawahara K, Kamitani T, Seki K, Naritomi K, Egawa Y, Hirano K, Tamura T, Tomiyasu T, Ishibashi Y, Simomura T, Nii K, Kinugasa T.

Study of colorectal cancer with Crohn's disease.

Anticancer Res. 2007 Nov-Dec; 27 (6A): 3771-4. 

Contents

Goto S, Noguchi A, Jinguji H, Takahara M.

The therapeutic potential of immuno-cell therapy of cancer in combination with aminobisphosphonates.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 3989-95. Review.

Taniguchi Y, Nishizawa T, Kouhchi C, Inagawa H, Yamaguchi T, Nagai S, Tamura A, Soma G.

Identification and characterization of lipopolysaccharide in acetic acid bacteria.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 3997-4002.

Yoshida A, Kohchi C, Inagawa H, Nishizawa T, Hori H, Soma G.

A soluble 17 kDa tumour necrosis factor (TNF) mutein, TNF-SAM2, with membrane-bound TNF-like biological characteristics.

Anticancer Res. Nov-Dec; 26 (6A): 4003-7.

Nakata K, Inagawa H, Nishizawa T, Kohchi C, Taniguchi Y, Yoshioka N, Soma G.

Unique molecular characteristics of the environmental responses of mucosal macrophages

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4009-14. Review.

Fujimoto K, Tomonaga M, Goto S.

A case of recurrent ovarian cancer successfully treated with adoptive immunotherapy and lentinan.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4015-8.

Kuroki Ma, Huang J, Shibaguchi H, Tanaka T, Zhao J, Luo N, Hachimine K, Kinugasa T, Maekawa S, Enatsu S, Hamanaka W, Fukami T, Kuroki Mo

Possible applications of antibodies or their genes in cancer therapy.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4019-25. Review.

Oshiro S, Tsugu H, Komatsu F, Ohnishi H, Ueno Y, Sakamoto S, Fukushima T, Soma G.

Evaluation of intratumoral administration of tumor necrosis factor-alpha in patients with malignant glioma.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4027-32.

Onishi H, Jimi S, Tsugu H, Lee S, Fukushima T.

Mechanisms of small globular protein-induced plasma membrane permeability and cytotoxicity in U87-MG human malignant glioblastoma cells.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4033-41.

Tsugu H, Onishi H, Fukushima T, Lee S

Anti-tumor activity of de novo designed small globular protein (SGP) in vivo.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4043-6.

Ohno S, Ohno Y, Nakada H, Suzuki N, Soma G, Inoue M.

Expression of Tn and sialyl-Tn antigens in endometrial cancer: its relationship with tumor-produced cyclooxygenase-2, tumor-infiltrated lymphocytes and patient prognosis.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4047-53.

Ohkura K, Hori H, Nagamune H.

Molecular dynamics of human-specific cytolysin: analysis of membrane binding motif for therapeutic application.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4055-62.

Ueda Y, Yabe K, Taira Z.

A bio-defensive function induced by low-dose lipopolysaccharide pre-treatment against CCl4-induced fulminant hepatic failure in rats.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4063-6.

Shibaguchi H, Luo NX, Kuroki Mo, Zhao J, Huang J, Hachimine K, Kinugasa T, Kuroki Ma.

A fully human chimeric immune receptor for retargeting T-cells to CEA-expressing tumor cells.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4067-72.

Ohkura K, Nagasawa H, Uto Y, Okamura N, Murakami A, Hori H.

The role of Gc protein oligosaccharide structure as a risk factor for COPD.

Anticancer Res. 2006 Nov-Dec; 26 (6A): 4073-8.

Contents

Ohno S, Ohno Y, Suzuki N, Inagawa H, Kohchi C, Soma G, Inoue M.

Multiple roles of cyclooxygenase-2 in endometrial cancer.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3679-87. Review.

Nagasawa H, Uto Y, Sasaki H, Okamura N, Murakami A, Kubo S, Kirk KL, Hori H.

Gc Protein (Vitamin D-binding Protein): Gc Genotyping and GcMAF Precursor Activity.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3689-95.

Tasaki A, Akiyoshi T, Koga K, Nakashima H, Yamanaka N, Kubo M, Matsumoto K, Kojima M, Tanaka M, Nakamura M, Katano M.

Immunohistochemical Staining of Hedgehog Pathway-related Proteins in Human Thymomas.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3697-701.

Koga K, Matsumoto K, Akiyoshi T, Kubo M, Yamanaka N, Tasaki A, Nakashima H, Nakamura M, Kuroki S, Tanaka M, Katano M.

Purification, Characterization and Biological Significance of Tumor-derived Exosomes.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3703-7.

Kaneko T, Goto S, Kato A, Akeyama A, Tomonaga M, Fujimoto K, Miyamoto Y, Eriguchi M, Egawa K.

Efficacy of Immuno-cell Therapy in Patients with Advanced Pancreatic Cancer.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3709-14.

Yamamoto M, Iwaasa M, Nonaka M, Tsugu H, Nabeshima K, Fukushima T.

Efficacy and Feasibility of Procarbazine, Ranimustine and Vincristine Chemotherapy, and the Role of Surgical Resection in Anaplastic Oligodendroglioma.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3715-23.

Kuroki Ma, Hachimine K, Huang J, Shibaguchi H, Kinugasa T, Maekawa S, Kuroki Mo.

Re-targeting of Cytotoxic T Lymphocytes and/or Natural Killer Cells to CEA-expressing Tumor Cells with Anti-CEA Antibody Activity.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3725-32. Review.

Kuroki Mo, Yamada H, Shibaguchi H, Hachimine K, Hirose Y, Kinugasa T, Ishida I, Kuroki Ma.

Preparation of Human IgG and IgM Monoclonal Antibodies for MK-1/Ep-CAM by using Human Immunoglobulin Gene-transferred Mouse and Gene Cloning of their Variable Regions.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3733-9.

Goto S, Kaneko T, Miyamoto Y, Eriguchi M, Kato A, Akeyama T, Fujimoto K, Tomonaga M, Egawa K.

Combined Immunocell Therapy Using Activated Lymphocytes and Monocyte-derived Dendritic Cells for Malignant Melanoma.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3741-6.

Hino M, Kohchi C, Nishizawa T, Yoshida A, Nakata K, Inagawa H, Hori H, Makino K, Terada H, Soma G.

Innate-immune Therapy for Lung Carcinoma Based on Tissue-macrophage Activation with Lipopolysaccharide.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3747-54.

Nakayama Y, Inoue Y, Nagashima N, Katsuki T, Matsumoto K, Kadowaki K, Shibao K, Tsurudome Y, Hirata K, Sako T, Nagata N, Itoh H.

Expression Levels of Thymidine Phosphorylase (TP) and Dihydropyrimidine Dehydrogenase (DPD) in Patients with Gastrointestinal Cancer.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3755-61.

Seo N, Ito T, Wang N, Yao X, Tokura Y, Furukawa F, Takigawa M, Kitanaka S.

Anti-allergic Psidium guajava Extracts Exert an Antitumor Effect by Inhibition of T Regulatory Cells and Resultant Augmentation of Th1 Cells.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3763-70.

Katano M, Morisaki T, Koga K, Nakamura M, Onishi H, Matsumoto K, Tasaki A, Nakashima H, Akiyoshi T, Nakamura M.

Combination Therapy with Tumor Cell-pulsed Dendritic Cells and Activated Lymphocytes for Patients with Disseminated Carcinomas.

Anticancer Res. 2005 Nov-Dec; 25 (6A): 3771-6.

Contents

Nakayama Y, Inoue Y, Nagashima N, Katsuki T, Matsumoto K, Shibao K, Tsurudome K, Hirata K, Sako T, Nagata N, Itoh H.

Relationships Between Local and Systemic Expression of Interleukin-12 and Plasma Levels of Vascular Endothelial Growth Factor in Patients with Gastric Cancer.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3289-94.

Ryoma Y, Moriya Y, Okamoto M, Kanaya I, Saito M, Sato M.

Biological Effect of OK-432 (Picibanil) and Possible Application to Dendritic Cell Therapy.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3295-301.

Kaneko T, Goto S, Kushima Y, Miyamoto Y, Eriguchi M, Nieda M, Egawa K.

A Report of Three Patients Treated with Immunocell Therapy with Imatinib Mesylate.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3303-309.

Kohchi C, Inagawa H, Hino M, Oda M, Nakata K, Yoshida A, Hori H, Terada H, Makino K, Takiguchi K, Soma G.

Utilization of Macrophages in Anticancer Therapy: The Macrophage Network Theory.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3311-20.

Egawa K.

Immuno-cell Therapy of Cancer in Japan.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3321-6.

Tomiyama M, Takahara M, Egawa K, Nieda M.

Mature dendritic cells are superior to immature dendritic cells in expanding antigen-specific naive and memory CD8+ T cells.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3327-33.

Ohno S, Ohno Y, Suzuki N, Kamei T, Koike K, Inagawa H, Kohchi C, Soma G, Inoue M.

Correlation of Histological Localization of Tumor-associated Macrophages with Clinicopathological Features in Endometrial Cancer.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3335-42.

Ohkura K, Nagamune H, Kourai H.

Structural Analysis of Human Specific Cytolysin Intermedilysin Aiming Application to Cancer Immunotherapy.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3343-53.

Shibaguchi H, Kuroki Ma, Kuroki Mo, Badran A, Hachimine K, Kinugasa T.

Cloning and Sequencing of Variable Region cDNAs of a Novel Human Monoclonal Antibody to Carcinoembryonic Antigen, and Generation of a Single Chain Variable Fragmented Antibody.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3355-60.

Nagasawa H, Sasaki H, Uto Y, Kubo S, Hori H.

Association of the Macrophage Activating Factor (MAF) Precursor Activitywith Polymorphism in Vitamin D-binding Protein.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3361-6.

Nagamune H, Ohkura K, Umezu K, Shouji H, Kourai H.

A Cell Membrane Modification Technique Using Domain 4 of Intermedilysin for Immunotherapy Against Cancer.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3367-72.

Kuroki Ma, Kuroki Mo, Shibaguchi H, Hachimine K, Kinugasa T, Badran A.

Tumor-targeting Viral Vectors for Cancer Gene Therapy by Using Antibodies or their Genes against Tumor-associated Antigens.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3373-7.

Noguchi K, Kuwada E, Goto S, Egawa K.

Tumor-Cell-specific Transcription of a Murine Histocompatibility ClassIb Q5 Gene.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3379-86.

Noguchi K, Isogai M, Kuwada E, Noguchi A, Goto S, Egawa K.

Detection of Anti-HLA-F Antibodies in Sera from Cancer Patients.

Anticancer Res. 2004 Sep-Oct; 24 (5C): 3387-92.

Contents

Seya T, Akazawa T, Uehori J, Matsumoto M, Azuma I, Toyoshima K.

Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4369-76. Review.

Kuroki Ma, Shibaguchi H, Imakiire T, Uno K, Shirota K, Higuchi T, Shitama T, Yamada H, Hirose Y, Nagata A, Kuroki Mo.

Immunotherapy and gene therapy of cancer using antibodies or their genes against tumor-associated antigens.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4377-81. Review.

Shibaguchi H, Arakawa F, Imakiire T, Kuroki Mo, Kuroki Ma.

cDNA cloning and sequencing of a novel monoclonal antibody to carcinoembryonic antigen and construction of a mouse/human chimeric antibody.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4383-8.

Nakagawa Y, Sirivichayakul S, Phanuphak P, Suda T, Mito K, Hori H.

Beneficial effect of macrophage activating agent NK-4 on Thai HIV-infected patients.

Anticancer Res. 2003 Nov-Dec; 23(6): 4389-94.

Ohno S, Suzuki N, Ohno Y, Inagawa H, Soma G, Inoue M.

Tumor-associated macrophages: foe or accomplice of tumors?

Anticancer Res. 2003 Nov-Dec; 23 (6): 4395-409. Review.

Naritomi K, Futami K, Arima S, Iwashita A.

Malignant potential regarding mucin phenotypes and endocrine cell differentiation in gastric adenocarcinoma.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4411-22.

Nakayama Y, Inoue Y, Minagawa N, Katsuki T, Nagashima N, Onitsuka K, Tsurudome Y, Sako T, Hirata K, Nagata N, Itoh H.

Relationships between S-100 protein-positive cells and clinicopathological factors in patients with colorectal cancer.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4423-6.

Nagasawa H, Mikamo N, Nakajima Y, Matsumoto H, Uto Y, Hori H.

Antiangiogenic hypoxic cytotoxin TX-402 inhibits hypoxia-inducible factor 1 signaling pathway.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4427-34.

Takayama N, Arima S, Haraoka S, Kotho T, Futami K, Iwashita A.

Relationship between the expression of adhesion molecules in primary esophageal squamous cell carcinoma and metastatic lymph nodes.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4435-42.

Kubo M, Morisaki T, Kuroki H, Tasaki A, Yamanaka N, Matsumoto K, Nakamura K, Onishi H, Baba E, Katano M.

Combination of adoptive immunotherapy with Herceptin for patients with HER2-expressing breast cancer.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4443-9.

Mohamad SB, Nagasawa H, Sasaki H, Uto Y, Nakagawa Y, Kawashima K, Hori H.

Gc protein-derived macrophage activating factor (GcMAF): isoelectric focusing pattern and tumoricidal activity.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4451-7.　

Morisaki T, Matsumoto K, Kuroki H, Kubo M, Baba E, Onishi H, Tasaki A, Nakamura M, Inaba S, Katano M.

Combined immunotherapy with intracavital injection of activated lymphocytes, monocyte-derived dendritic cells and low-dose OK-432 in patients with malignant effusion.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4459-65.

Nakagawa T, Ma BY, Uemura K, Oka S, Kawasaki N, Kawasaki T.

Role of mannan-binding protein, MBP, in innate immunity.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4467-71. Review.

Fukushima T, Yamamoto M, Oshiro S, Tsugu H, Hirakawa K, Soma G.

Recombinant mutant human tumor necrosis factor-alpha (TNF-SAM2) immunotherapy with ranimustine chemotherapy and concurrent radiation therapy for malignant astrocytomas.

Anticancer Res. 2003 Nov-Dec; 23 (6): 4473-81.

Contents

Kuroki Ma, Ueno A, Matsumoto H, Abe H, Li T, Imakiire T, Yamauchi Y, Uno K, Shirota K, Shibaguchi H, Kuroki Mo.

Significance of tumor-associated antigens in the diagnosis and therapy ofcancer: an overview.

Anticancer Res. 2002 Nov-Dec; 22 (6): 4255-64. Review.

Yamamoto M, Ueno Y, Hayashi S, Fukushima T.

The role of proteolysis in tumor invasiveness in glioblastoma and metastatic brain tumors.

Anticancer Res. 2002 Nov-Dec; 22 (6): 4265-8. Review.

Ohno S, Inagawa H, Soma G, Nagasue N.

Role of tumor-associated macrophage in malignant tumors: should the location of the infiltrated macrophages be taken into account during evaluation?

Anticancer Res. 2002 Nov-Dec; 22 (6): 4269-76. Review.

Takiguchi K, Inagawa H, Nishizawa T, Kohchi C, Soma G.

Perspectives for antitumor therapy based on the recognition mechanism by which macrophages identify undesirable foreign and native cells and molecules.

Anticancer Res. 2002 Nov-Dec; 22 (6): 4277-80. Short review.

Hamada I, Kato M, Yamasaki T, Iwabuchi K, Watanabe T, Yamada T, Itoyama S, Ito H, Okada K.

Clinical effects of tumor-associated macrophages and dendritic cells on renal cell carcinoma.

Anticancer Res. 2002 Nov-Dec; 22 (6): 4281-4.

Arakawa F, Shigbaguchi H, Xu Z, Kuroki M.

Targeting of T cells to CEA-expressing tumor cells by chimeric immune receptors with a highly specific single-chain anti-CEA activity.

Anticancer Res. 2002 Nov-Dec; 22 (6): 4285-90.

Nakayama Y, Nagashima N, Mianagawa N, Inoue Y, Katsuki T, Onitsuka K, Sako T, Hirata K, Nagata N, Itoh H.

Relationships between tumor-associated macrophages and clinicopathological factors in patients with colorectal cancer.

Anticancer Res. 2002 Nov-Dec; 22 (6): 4291-6.

Mohamad S, Nagasawa H, Uto Y, Hori H.

Preparation of Gc protein-derived macrophage activating factor (GcMAF) and its structural characterization and biological activities.

Anticancer Res. 2002 Nov-Dec; 22 (6): 4297-300. 

Contents

Hamada I, Kato M, Okada K.

Multi-cytokine therapy for advanced renal cell carcinoma: determination of the minimal effective dose.

Anticancer Res. 2002 Jul-Aug; 22 (4): 2429-36.

Nakayama Y, Sako T, Shibao K, Okazaki K, Rempo N, Onitsuka K, Minagawa N, Akahane K, Nagashima N, Nagata N, Itoh H.

Prognostic value of plasma vascular endothelial growth factor in patients with colorectal cancer.

Anticancer Res. 2002 Jul-Aug; 22 (4): 2437-42.

Khare PD, Liao S, Hirose Y, Kuroki Mo, Fujimura S, Yamauchi Y, Miyajima-Uchida H, Kuroki Ma.

Tumor growth suppression by a retroviral vector displaying scFv antibody to CEA and carrying the iNOS gene.

Anticancer Res. 2002 Jul-Aug; 22 (4): 2443-6.

Yamamoto M, Oshiro S, Tsugu H, Hirakawa K, Ikeda K, Soma G, Fukushima T.

Treatment of recurrent malignant supratentorial astrocytomas with carboplatin and etoposide combined with recombinant mutant human tumor necrosis factor-alpha.

Anticancer Res. 2002 Jul-Aug; 22 (4): 2447-53.

Nakamoto T, Inagawa H, Nishizawa T, Honda T, Kanou J, Nagasue N, Soma G.

Antitumor effects of isolated hypoxic hepatic perfuあsion (IHHP) with high-dose TNF against colonic liver metastases in a rat model.

Anticancer Res. 2002 Jul-Aug; 22 (4): 2455-9.

Goto S, Shirotani N, Hatakeyama M, Tagami C, Arakawa H, Kuwata E, Noguchi K, Egawa K.

Clinical benefit of non-toxic therapy in patients with advanced cancer (opinion).

Anticancer Res. 2002 Jul-Aug; 22 (4): 2461-4.

Contents

Fukumoto M, Takahashi JA, Murai N, Ueba T, Kono K, Nakatsu S.

Induction of apoptosis in glioma cells: an approach to control tumor growth by blocking basic fibroblast growth factor autocrine loop.

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4059-65. Review.

Kuroki Ma, Arakawa F, Khare PD, Kuroki Mo, Liao S, Matsumoto H, Abe H, Imakiire T.

Specific targeting strategies of cancer gene therapy using a single-chain variable fragment (scFv) with a high affinity for CEA.

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4067-71. Review.

Nomura T, Hasegawa H.

Chemokines and anti-cancer immunotherapy: anti-tumor effect of EBI1-ligand chemokine (ELC) and secondary lymphoid tissue chemokine (SLC).

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4073-80. Review.

Yamamoto M, Fukushima T, Ueno Y, Hayashi S, Kimura H, Soma G, Tomonaga M.

Clinical significance of the expression of endothelial-monocyte activating polypeptide II (EMAPII) in the treatment of glioblastoma with recombinant mutant human tumor necrosis factor-alpha (TNF-SAM2).

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4081-6.

Nakamoto T, Inagawa H, Takagi K, Soma G.

A new method of antitumor therapy with a high dose of TNF perfusion for unresectable liver tumors.

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4087-96. Review.

Nakayama Y, Sako T, Shibao K, Onitsuka K, Nagashima N, Hirata K, Nagata N, Itoh H.

Relationship between plasma levels of vascular endothelial growth factor and serum levels of interleukin-12 in patients with colorectal cancer.

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4097-102.

Tachikawa D, Arima S, Futami K.

Immunohistochemical expression of thymidylate synthase as a prognostic factor and as a chemotherapeutic efficacy index in patients with colorectal carcinoma.

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4103-7.

Kido T, Mori K, Daikuhara H, Tsuchiya H, Ishige A, Sasaki H.

The protective effect of hochu-ekki-to (TJ-41), a Japanese herbal medicine, against HSV-1 infection in mitomycin C-treated mice.

Anticancer Res. 2000 Nov-Dec; 20 (6A): 4109-13.

Contents

Yoshino S, Kato M, Okada K.

Clinical significance of angiogenesis, proliferation and apoptosis in renal cell carcinoma.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 591-4.

Tachikawa D, Arima S, Futami K, Iwashita A.

Do the expression of CD44, apoptosis and thymidylate synthase inhibition rate correlate with the efficacy of chemotherapy in colorectal cancer?

Anticancer Res. 2000 Jan-Feb; 20 (1C): 595-600.

Emoto M, Ishiguro M, Iwasaki H, Kikuchi M, Kawarabayashi T.

TNP-470 inhibits growth and the production of vascular endothelial growth factor of uterine carcinosarcoma cells in vitro.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 601-4.

Oshiro S, Fukushima T, Tomonaga M, Black KL.

Response of MHC class-1 antigen on rat glioma cells to cytokines.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 605-10.

Yamamoto M, Fukushima T, Hayashi S, Ikeda K, Tsugu H, Kimura H, Soma G, Tomonaga M.

Correlation of the expression of nuclear factor-kappa B, tumor necrosis factor receptor type 1 (TNFR 1) and c-Myc with the clinical course in the treatment of malignant astrocytomas with recombinant mutant human tumor necrosis factor-alpha (TNF-SAM2).

Anticancer Res. 2000 Jan-Feb; 20 (1C): 611-8.

Nakamoto T, Inagawa H, Takagi K, Tashiro K, Yoshimura H, Nishizawa T, Honda T, Kanou J, Muto Y, Amm E, Soma G.

Pharmacokinetics of isolated hepatic perfusion with high dose tumor necrosis factor in rat model.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 619-22.

Nakamoto T, Inagawa H, Takagi K, Tashiro K, Yoshimura H, Nishizawa T, Honda T, Kanou J, Muto Y, Soma G.

Reduction of hepatotoxicity of tumor necrosis factor in isolated hepatic perfusion by administration of glucocorticoid as well as lipopolysaccharide.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 623-8.

Yoshimura H, Chikamoto A, Honda T, Tashiro K, Nakamoto T, Takano M, Takagi K, Nagasue N, Soma G.

Relationship between microvessel quantification and inducibility of endogenous tumor necrosis factor in colorectal adenocarcinoma.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 629-33.

Nakayama Y, Shibao K, Sako T, Ohta R, Onitsuka K, Hirata K, Nagata N, Itoh H.

Serum levels of interleukin-12 in patients with gastrointestinal cancer.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 635-40.

Kato M, Miyakawa M, Okada K.

Neuro-psychological discorders and renal cell carcinoma: a case report and a psychological study of urological cancer patients.

Anticancer Res. 2000 Jan-Feb; 20 (1C): 641-3.

Contents

Eggermont AM.

TNF alpha in isolated perfusion systems: success in the limb, developments for the liver credits, debits and future perspectives.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3899-905. Review.

Sasaki S, Tsuji T, Asakura Y, Fukushima J, Okuda K.

The search for a potent DNA vaccine against AIDS: the enhancement of immunogenicity by chemical and genetic adjuvants.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3907-15. Review.

Katano M, Morisaki T.

The past, the present and future of the OK-432 therapy for patients with malignant effusions.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3917-25. Review.

Okada H.

The possible role of sense and antisense peptide interactions in the generation and maintenance of the tertiary structure of a protein.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3927-30.

Yamasaki K, Hasegawa S, Futami K, Arima S.

Endogenous TNF induction therapy using rTNF-SAM2 in patients with pulmonary metastases from colorectal cancer.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3931-6.

Tomita A, Fuchino Y, Otsuka K, Shinohara T, Tanaka SN, Umeno T, Ikeda S.

Clinical effects of exogenous/endogenous TNF therapy on metastatic lesions of 34 colorectal cancer patients.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3937-9.

Kato M, Shinohara H, Goto S, Takagi K, Soma G.

Clinical experience of EET therapy for 75 advanced cancer patients.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3941-9.

Sato M, Goto S, Kaneko R, Ito M, Sato S, Takeuchi S.

Impaired production of Th1 cytokines and increased frequency of Th2 subsets in PBMC from advanced cancer patients.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3951-5.

Inagawa H, Nishizawa T, Honda T, Nakamoto T, Takagi K, Soma G.

Mechanisms by which chemotherapeutic agents augment the antitumor effects of tumor necrosis factor: involvement of the pattern shift of cytokines from Th2 to Th1 in tumor lesions.

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3957-64.

Fukushima T, Yamamoto M, Ikeda K, Tsugu H, Kimura H, Soma G, Tomonaga M.

Treatment of malignant astrocytomas with recombinant mutant human tumor necrosis factor-alpha (TNF-SAM2).

Anticancer Res. 1998 Sep-Oct; 18 (5D): 3965-70.