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Dan Rosen
Chief Executive Officer @ gluECO Adhesives, LLC
May 17, 2025
In the world of skincare, success often hinges on one simple question: How long does the product stay where you put it? Despite advances in active ingredients and formulations, the effectiveness of many topicals—especially in cosmetics, dermatology, and therapeutics—is cut short by a basic problem: skin contact time.
The Challenge: Keeping It Where It Belongs
Products designed to deliver benefits through the skin face a frustrating array of obstacles:
Sweat and water easily wash them away.
Low loading limits mean only a small percentage of actives can be included before the product becomes unstable or unpleasant.
Sticky or greasy textures reduce user compliance and comfort.
Product transfer to clothing, bedding, or other surfaces dilutes effectiveness and creates mess.
Inconsistent skin adhesion leads to uneven dosing and unpredictable results.
These issues don’t just frustrate consumers—they also limit innovation in areas like transdermal delivery, anti-aging treatments, and therapeutic cosmetics.
Introducing DermAmaize®: A Natural Solution for Long-Lasting Adhesion
DermAmaize® is a proprietary biopolymer platform derived from zein, a renewable corn protein. Engineered for dermal adhesion, this transparent, breathable film-forming matrix holds active ingredients on the skin for extended periods—without the drawbacks of traditional binders or adhesives.
Why it stands out:
Water and sweat resistance: Forms a durable film that stays put—even under real-world conditions.
Non-greasy, non-sticky: Smooth and clean-feeling, ideal for daily wear.
Higher active loading: Compatible with a wide range of ingredients, including oils, botanicals, peptides, and more.
Transfer resistance: Won’t stain fabrics or wipe away on contact.
Fully compostable and biobased: Aligns with clean beauty and sustainability goals.
Reef safe: Free from oxybenzone, octinoxate, and microplastics that harm marine ecosystems.
DermAmaize® enables formulators to create invisible topical patches, overnight treatments, and extended-release skincare that consumers can trust—on the move, overnight, or all day long.
Whether you’re developing the next breakthrough in personal care or looking to elevate an existing product, DermAmaize® offers a reliable, natural foundation for performance, safety, and sustainability.
For decades, shellac—a resin secreted by the lac beetle—has been the industry standard for glazes and coatings in confectionery, pharmaceuticals, and even wood finishes. It provides a glossy surface, moisture resistance, and protection for delicate actives. But today, markets are shifting. Consumers are demanding clean-label, vegan, and sustainable alternatives. At the same time, formulators need greater flexibility and performance in encapsulation and controlled release.
Enter zein, a natural protein derived from corn, which is rapidly emerging as the next-generation alternative to shellac.
Shellac has been trusted for centuries, but it comes with limitations that no longer fit the needs of global markets:
Animal origin: Shellac is insect-derived, making it unsuitable for vegan, vegetarian, kosher, or certain halal certifications.
Brittle films: While providing good barriers, shellac coatings are prone to cracking unless softened with plasticizers.
Processing restrictions: Shellac requires alcohol or alkaline solutions, and its pH-dependent solubility limits release options.
Market perception: In an era of sustainability and transparency, many brands hesitate to rely on animal-derived materials.
Zein solves these challenges while opening new opportunities. As a plant protein sourced from corn gluten meal (a byproduct of the starch and ethanol industries), zein is renewable, compostable, and label-friendly. But it’s not just sustainable—it’s smarter and more versatile:
Flexible, durable films: Zein creates tough yet flexible barriers against oxygen and oils without cracking.
Encapsulation power: Unlike shellac, zein naturally forms micro- and nanoparticles, making it ideal for protecting flavors, vitamins, nutraceuticals, and pharmaceuticals.
Controlled release: Its tunable solubility enables sustained or targeted delivery, including intestine-specific release.
Green processing: Zein dissolves in aqueous ethanol and blends easily with other biopolymers and waxes, supporting environmentally friendly manufacturing.
Regulatory acceptance: Recognized as GRAS by the FDA, zein is already widely used in food, pharma, and personal care.
Applications Across Industries
Confectionery: Vegan-friendly glosses, protective nut and fruit coatings, and anti-stick finishes for gummies.
Pharma/Nutraceuticals: Advanced encapsulation for bioactives, with pH-sensitive release profiles.
Personal Care: Biobased film formers for skin patches, hair treatments, and topical delivery systems.
Packaging: Sustainable coatings for paper and fiber, offering water and oil resistance without PFAS.
Agriculture: Encapsulation of fertilizers and pesticides for controlled release, improved efficiency, and reduced environmental impact.
Zein doesn’t just match shellac—it surpasses it by enabling entirely new applications outside shellac’s reach:
Gluten replacement: Zein mimics gluten’s elasticity in baking, creating better textures in gluten-free products.
Vegan cheese: Zein forms the structure and stretch missing in dairy-free cheese formulations.
Cultured meats: As a biocompatible protein scaffold, zein supports cell growth for lab-grown meat production.
Adhesives: Zein serves as a natural, compostable binder and adhesive for packaging, composites, and wood products.
Shellac had its place in history—but zein represents the future. With superior flexibility, encapsulation capability, and consumer-friendly credentials, zein is the sustainable solution that meets both technical requirements and market expectations.
As industries move away from animal-derived and petroleum-based materials, zein is leading the way toward a smarter, greener generation of coatings and encapsulation agents.