The final design integrates three primary subsystems into a single platform for preclinical 3D ultrasound imaging. The mouse tank provides a waterproof enclosure that allows the mouse's body to remain submerged in heated water while keeping the head accessible for anesthetic delivery and monitoring. This water environment ensures proper acoustic coupling between the ultrasound probe and the subject, which is essential for acquiring high-quality images. Adjacent to the tank is the electronics enclosure, which houses the system's electrical components, including the motor drivers, power distribution hardware, and control electronics, while providing separation from the water-filled imaging environment for improved safety and organization. Above the tank, the motorized positioning stage supports and translates the Clarius ultrasound probe along the X-axis and Z-axis with precise, repeatable motion. By automating probe positioning and integrating all components into a single portable platform, the system improves scan repeatability, reduces setup time, and enables the collection of consistent ultrasound data for 3D volumetric reconstruction.Â
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