Exploring the next frontiers and embracing non-traditional research directions.
Translating Our Research to Help Optimize Human Health, Fitness, and Thriving for all People
Bioengineering faculty featured prominently in the $220M Wu Tsai Human Performance Alliance
The Wu Tsai Human Performance Alliance is a collaborative effort with six public and private institutions to transform global human health.
The UC San Diego team is led by Professor and IEM Director Andrew McCulloch and includes nine dynamic and innovative faculty from Bioengineering, Mechanical and Aerospace Engineering, Orthopedic Surgery and Biological Sciences including Professors Adam Engler, Stephanie Fraley, Robert Sah and Daniela Valdez-Jasso in Bioengineering, as well as our many collaborators at the other institutions including Professor Todd Coleman at Stanford. UC San Diego is home to the Multiscale Athlete moonshot and the Triton Center for Performance and Injury Science innovation hub of the alliance.
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Creating New Raman Scattering Microscopic Views into Cellular Dynamics
A new BioEng assistant professor interviews Lingyan Shi, PhD about her award-winning research program.
With Gene Therapy, Scientists Develop Opioid-Free Solution for Chronic Pain
The researchers report their findings in a paper published Mar. 10 in Science Translational Medicine and the work was highlighted by Francis Collins in the NIH Director’s Blog.
The idea for such a treatment emerged when Moreno was a Ph.D. student in UC San Diego bioengineering Professor Prashant Mali’s lab. Mali had been investigating the possibility of applying CRISPR-based gene therapy approaches to rare as well as common human diseases.
TemPredict Study Demonstrates Distributed, Passive Fever Detection, and Generalized Sickness Detection Potential with Live Trial
“I still don’t have an office on campus” Dr. Smarr laughs. “True story: I started at UC San Diego in the first week of March, 2020. I showed up and I said ‘where do I put my stuff.’ They told me they still needed to clean out the office I would use, so come back next week. Next week, everything shut down, so I still don’t have an office.” Benjamin Smarr was coming from Berkeley, where he’d been an NIH K99 fellow studying circadian rhythms and reproductive neuroendocrinology in rodent models. Luckily, as it would turn out, he had been transitioning from wet lab work to data science, using implanted sensors to capture physiological time series from his experimental subjects, and developing methods for extracting patterns in these time series that could predict things like pregnancy outcomes or hormonal disruptions. When COVID-19 hit, and he couldn’t find space on campus, it pushed him to complete his conversion to digital science.
New Insights for Developing Therapies for Muscle Disease, Injury and Atrophy
By studying how different pluripotent stem cell lines build muscle, Professor Subramaniam of UC San Diego Bioengineering led a multi-site collaboration to discovered how epigenetic mechanisms can be triggered to accelerate muscle cell growth at different stages of stem cell differentiation.
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Ecosystem Dynamics Reveal Possible Microbial Culprits for Inflammatory Bowel Disease
Combining ecosystem dynamics, the microbiome, metabolomics, and time series analysis make a detailed case against specific strains of E. coli as having means, opportunity, and motive.