Publications

1. Zhang CY, Hung CH, Hsiao YL, Chang TM, Su YC, Wang LC (co-corresponding), Wang SM, Chen SH. 2024.03. Miltefosine reduces coxsackievirus B3 lethality of mice with enhanced STAT3 activation. Antivir. Res. 223:105824. https://doi.org/10.1016/j.antiviral.2024.105824 (6/36 in Virology, IF 7.6)

2. Lin YJ, Wang LC (co-first), Tsai HP, Chi CY, Chang CP, Chen SH, Wang SM. 2023.10. Antiviral and immunoregulatory effects of curcumin on coxsackievirus B3-infected hepatitis. Virus Res. 336:199203. https://doi.org/10.1016/j.virusres.2023.199203 (13/36 in Virology, IF 5.0)

3. Kao YS, Wang LC (co-first), Chang PC, Lin HM, Lin YS, Yu CY, Chen CC, Lin CF, Yeh TM, Wan SW, Wang JR, Ho TS, Chu CC, Zhang BC, Chang CP. 2023.03. Negative regulation of type I interferon signaling by integrin-linked kinase permits dengue virus replication. PLOS Pathog. 13:e1011241. https://doi.org/10.1371/journal.ppat.1011241 (8/37 in Virology, IF 7.4)

4. Wang LC, Tsai HP, Chen SH, Wang SM. 2022.10. Therapeutics for fulminant hepatitis caused by enteroviruses in neonates.  Front. Pharmacol. 13:1014823. https://doi.org/10.3389/fphar.2022.1014823 (50/279 in Pharmacology and Pharmacy, IF 5.9)

5. Wang LC, Wu SR, Yao HW, Ling P, Perng GC, Chiu YC, Hsu SM, Chen SH. 2022.08. Suppression of annexin A1 and its receptor reduces herpes simplex virus 1 lethality in mice. PLOS Pathog. 18:e1010692. https://doi.org/10.1371/journal.ppat.1010692 (8/37 in Virology, IF 7.4)

6. Tsai MS, Chen SH, Chang CP, Hsiao YL, Wang LC. 2022.03. Integrin-linked kinase reduces H3K9 trimethylation to enhance herpes simplex virus 1 replication. Front. Cell. Infect. Microbiol. 12:814307. https://doi.org/10.3389/fcimb.2022.814307 (33/136 in Microbiology, IF 6.1)

7. Tsai MS, Wang LC (co-first author), Wu HL, Tzeng SF, Conway EM, Hsu SM, Chen SH. 2022.02. Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses. J. Neuroinflammation. 19:66. https://doi.org/10.1186/s12974-022-02426-w (30/161 in Immunology, IF 9.6)

8. Tsai MS, Wang LC, Tsai HY, Lin YJ, Wu HL, Tzeng SF, Hsu SM, Chen SH. 2021.10. Microglia reduce herpes simplex virus 1 lethality of mice with decreased T cell and interferon responses in brains. Int. J. Mol. Sci. 22:12457. https://doi.org/10.3390/ijms222212457 (69/296 in Biochemistry & Molecular Biology, IF 6.2)

9. Chen SH, Lin YJ, Wang LC, Tsai HY, Yang CH, Teng YT, and Hsu SM. 2021.09. Doxycycline ameliorates the severity of experimental proliferative vitreoretinopathy in mice. Int. J. Mol. Sci. 22:11670. https://doi.org/10.3390/ijms222111670 (69/296 in Biochemistry & Molecular Biology, IF 6.2)

10. Yao HW, Wang LC (co-first author), Tsai HY, Fang YH, Zheng CF, Chen SH, and Hsu SM. 2020.01. Bortezomib induces HSV-1 lethality in mice with neutrophil deficiency. J. Leukoc. Biol. 107:105-112. https://doi.org/10.1002/JLB.4AB1019-495R (19/73 in Hematology, IF 4.0)

11. Lin YW, Wang LC (co-first author), Lee CK, Chen SH. 2018.07. Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses. Sci. Rep. 8:12184. https://www.nature.com/articles/s41598-018-30631-2 (15/69 in Multidisciplinary Sciences; IF 4.0)

12. Wang LC, Yao HW, Chang CF, Wang SW, Wang SM, Chen SH. 2017.12. Suppression of interleukin-6 increases enterovirus A71 lethality in mice. J. Biomed. Sci. 24:94. http://dx.doi.org/10.1186/s12929-017-0401-5 (20/136 in Medicine, Research & Experimental; IF 5.2)

13. Huang CY, Yao HW, Wang LC (co-first author), Shen FH, Hsu SM, Chen SH. 2017.01. Thymidine kinase-negative herpes simplex virus 1 can efficiently establish persistent infection in neural tissues of nude mice. J. Virol. 91: e01979-16. http://dx.doi.org/10.1128/JVI.01979-16 (8/36 in Virology, IF 4.3)

14. Wang LC, Chen SO, Chang SP, Lee YP, Yu CK, Chen CL, Tseng PC, Hsieh CY, Chen SH, Lin CF. 2015.06. Enterovirus 71 proteins 2A and 3D antagonize the antiviral activity of gamma interferon via signaling attenuation. J. Virol. 89:7028-7037. http://dx.doi.org/10.1128/JVI.00205-15 (8/36 in Virology; IF 4.3)

15. Shen FH, Tsai CC, Wang LC (2nd author), Chang KC, Tung YY, Su IJ, Chen SH. 2013.05. Enterovirus 71 infection increases expression of interferon-gamma-inducible protein 10 which protects mice by reducing viral burden in multiple tissues. J. Gen. Virol. 94:1019-1027. http://dx.doi.org/10.1099/vir.0.046383-0 (18/36 in Virology; IF 2.8)

16. Wang LC, Kao CM, Ling P, Su IJ, Chang TM, Chen SH. 2012.10. CD4 T-cell-independent antibody response reduces enterovirus 71 lethality in mice by decreasing tissue viral loads. Clin. Dev. Immunol. 2012:580696. http://dx.doi.org/10.1155/2012/580696 (56/151 in Immunology; IF 3.6)

• 陳舜華和王莉萩.2019.04. 腸病毒七十一型的台灣經驗: 從流行病學及臨床到基礎科學的新視野.第三章第六節.初版.臺北市: 科技部生科司台灣重要新興感染症辦公室.p.130-137.

Li-Chiu Wang and Shun-Hua Chen. 2019.04. The Experience of Handling EV71 (Enterovirus 71) Infection in Taiwan. Section 6, Chapter 3,1st edition. Taipei. The project of Taiwan Emerging and Re-emerging Infectious Disease, Ministry of Science and Technology. p.130-137.