LASM  Publications

2025

Manabe, M., Nakamura, T., Sato, K., Hayashi, N., Kouguchi, H., Nakao, R., Hidaka, M., Matsuyama, H., Nonaka, N. and Morimatsu, M. 2025. Efferocytosis-Driven M2 Macrophage Impairs Fibrotic Encapsulation and Promotes Echinococcus multilocularis Growth in Cotton Rats (Sigmodon Hispidus). Microsc. Microanal. in press.

Sato, K., Hikosaka, N., Kouguchi, H., Irie, T., Morimatsu, M. and Agui, T. Narrowing the region of candidate genes that control the development of protoscoleces of Echinococcus multilocularis in the mouse liver. Infect Genet Evol 127: 105704, 2025. 

2024

Sato, K., Nakamura, T., Morimatsu, M. and Agui, T. Functional Analysis of Oligoadenylate Synthetase in the Emu (Dromaius novaehollandiae). Animals (Basel) 14, 2024.

Kira, S., Namba, T., Hiraishi, M., Nakamura, T., Otani, Y., Kon, Y. and Ichii, O. Species-specific histological characterizations of renal tubules and collecting ducts in the kidneys of cats and dogs. PLoS One 19: e0306479,  2024. 

Nakanishi, K., Akasaka, T., Hayashi, H., Yoshihara, K., Nakamura, T., Nakamura, M., Meerbeek, B. V. and Yoshida, Y. From Tooth Adhesion to Bioadhesion: Development of Bioabsorbable Putty-like Artificial Bone with Adhesive to Bone Based on the New Material "Phosphorylated Pullulan". Materials (Basel) 17, 2024. 

Namba, T., Ichii, O., Natsuga, K., Nakamura, T., Otani, Y. and Kon, Y. Collagen 17A1 in the Urothelium Regulates Epithelial Cell Integrity and Local Immunologic Responses in Obstructive Uropathy. Am J Pathol 194: 1550-1570, 2024. 

Rubel, M. Z. U., Ichii, O., Namba, T., Masum, M. A., Chuluunbaatar, T., Hiraishi, M., Nakamura, T. and Kon, Y. Systemic autoimmune abnormalities alter the morphology of mucosa-associated lymphoid tissues in the rectum of MRL/MpJ-Fas(lpr/lpr) mice. Exp Anim 73: 270-285, 2024.

Takahashi, N., Ichii, O., Hiraishi, M., Namba, T., Otani, Y., Nakamura, T. and Kon, Y. Phenotypes of streptozotocin-induced gestational diabetes mellitus in mice. PLoS One 19: e0302041, 2024.

Takahashi, N., Ichii, O., Hiraishi, M., Namba, T., Otani, Y., Nakamura, T. and Kon, Y. Phenotypes of streptozotocin-induced gestational diabetes mellitus in mice. PLoS One 19: e0302041, 2024.

Yamanaka, R., Ichii, O., Nakamura, T., Otani, Y., Namaba, T. and Kon, Y. Effects of autoimmune abnormalities on fertility and placental morphology in mice. Autoimmunity 57: 2319209, 2024.

2023

Namba T, Ichii O, Okamura T, Nakano K, Nakamura T, Otani Y, Kon Y. Ameliorated renal pathological feature in MRL/MpJ-Faslpr/lpr background interleukin-36 receptor-deficient mice. Microsc Microanal 29, 675-685, 2023. 

Katayama Y, Ichii O, Nakamura T, Yanase K, Hiraishi M, Namba T, Otani Y, Ikeda T, Tsuji E, Tsuzuki N, Kobayashi K, Kon Y, Nishimura T. Structural features of connective tissue formed around resin implants subcutaneously embedded in dairy cows. Animals (Basel) 13, 3700, 2023. 

Sato K, Morimatsu M, Agui T.Verification of quantitative trait loci located on chromosome 4 that affect mouse behaviors by use of congenic and subcongenic strains generated from DBA/2 and C57BL/6 mice. Jpn J Vet Res 71, 48-55, 2023

Hosotani M, Ichii O, Namba T, Masum MA, Nakamura T, Hasegawa Y, Watanabe T, Kon Y. Expression of Indian hedgehog signaling in murine oviductal infundibulum and its relationship with epithelial homeostasis. Cell Tissue Res. 391, 595-609, 2023

Zhu Z, Kitano T, Morimatsu M, Ochiai K, Ishiguro-Oonuma T, Oosumi K, Lin X, Orino K, Yoshikawa Y. A highly conserved region in BRCA2 suppresses the RAD51-interaction activity of BRC repeats. Vet Sci 10, 145, 2023.

2022

Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y. BRCA2 C-terminal RAD51-binding domain confers resistance to DNA-damaging agents. Int J Mol Sci 23, 4060, 2022

Shimakawa K, Ochiai K, Hirose S, Tanabe E, Michishita M, Sakaue M, Yoshikawa Y, Morimatsu M, Tajima T, Watanabe M, Tanaka Y. Canine mammary tumor cell lines derived from metastatic foci show increased RAD51 expression but diminished radioresistance via p21 inhibition. Vet Sci 9, 703, 2022

Maeda M, Ochiai K, Michishita M, Morimatsu M, Sakai H, Kinoshita N, Sakaue M, Onozawa E, Azakami D, Yamamoto M, Ishioka K, Sadahira T, Watanabe M, Tanaka Y. In vitro anticancer effects of alpelisib against PIK3CA‑mutated canine hemangiosarcoma cell lines. Oncol Rep 47, 84, 2022

2021以前

Uemura, M., Ochiai, K., Morimatsu, M., Michishita, M., Onozawa, E., Azakami, D., Uno, Y., Yoshikawa, Y., Sasaki, T., Watanabe, M. and Omi, T. 2020. The canine RAD51 mutation leads to the attenuation of interaction with PALB2. Vet Comp Oncol 18: 247-255.

Kawakami, S., Michishita, M., Sakaue, M., Morimatsu, M., Uemura, M., Kashiwagi, N., Maeda, M., Machida, Y., Azakami, D., Egusa, A. S., Onozawa, E., Ishioka, K., Watanabe, M., Tanaka, Y., Omi, T. and Ochiai, K. 2020. Novel canine isocitrate dehydrogenase 1 mutation Y208C attenuates dimerization ability. Oncol Lett 20: 351.

Wang, J., Dang, R., Miyasaka, Y., Hattori, K., Torigoe, D., Okamura, T., Tag-Ei-Din-Hassan, H. T., Morimatsu, M., Mashimo, T. and Agui, T. 2019. Null mutation of the endothelin receptor type B gene causes embryonic death in the GK rat. PLoS One 14: e0217132.

Boonyarattanasoonthorn, T., Elewa, Y. H. A., Tag-El-Din-Hassan, H. T., Morimatsu, M. and Agui, T. 2019. Profiling of cellular immune responses to Mycoplasma pulmonis infection in C57BL/6 and DBA/2 mice. Infect Genet Evol 73: 55-65.

Tag-El-Din-Hassan, H. T., Morimatsu, M. and Agui, T. 2018. Functional analysis of duck, goose, and ostrich 2'-5'-oligoadenylate synthetase. Infect Genet Evol 62: 220-232.

Ochiai, K., Azakami, D., Morimatsu, M., Hirama, H., Kawakami, S., Nakagawa, T., Michishita, M., Egusa, A. S., Sasaki, T., Watanabe, M. and Omi, T. 2018. Endogenous Leu332Gln mutation in p53 disrupts the tetramerization ability in a canine mammary gland tumor cell line. Oncol Rep 40: 488-494.

Kawakami, S., Ochiai, K., Azakami, D., Kato, Y., Michishita, M., Morimatsu, M., Ishiguro-Oonuma, T., Onozawa, E., Watanabe, M. and Omi, T. 2018. R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes. Veterinary Research Communications 42: 49-56.

Islam, M. A., Torigoe, D., Kameda, Y., Irie, T., Kouguchi, H., Nakao, R., Masum, M. A., Ichii, O., Kon, Y., Tag-El-Din-Hassan, H. T., Morimatsu, M., Yagi, K. and Agui, T. 2018. Analysis for genetic loci controlling protoscolex development in the Echinococcus multilocularis infection using congenic mice. Infect Genet Evol 65: 65-71.

Abbas, R. M. F., Tag-El-Din-Hassan, H. T., Boonyarattanasoonthorn, T., Aoshima, K., Morimatsu, M. and Agui, T. 2018. Immune cellular responses to Sendai virus infection in D2.B6-Sen1Sen2Sen3 congenic mice, of which three quantitative trait loci responsible for the resistance to infection were introgressed from C57BL/6 mouse into DBA/2 mouse. Japanese Journal of Veterinary Research 66: 93-103.

Tag-El-Din-Hassan, H. T., Sasaki, N., Torigoe, D., Morimatsu, M. and Agui, T. 2017. Analysis of the Relationship Between Enzymatic and Antiviral Activities of the Chicken Oligoadenylate Synthetase-Like. Journal of Interferon and Cytokine Research 37: 71-80.

Okamatsu-Ogura, Y., Fukano, K., Tsubota, A., Nio-Kobayashi, J., Nakamura, K., Morimatsu, M., Sakaue, H., Saito, M. and Kimura, K. 2017. Cell-cycle arrest in mature adipocytes impairs BAT development but not WAT browning, and reduces adaptive thermogenesis in mice. Scientific Reports 7.

Kato, Y., Ochiai, K., Kawakami, S., Nakao, N., Azakami, D., Bonkobara, M., Michishita, M., Morimatsu, M., Watanabe, M. and Omi, T. 2017. Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines. Bmc Veterinary Research 13.

Fujimoto, Y., Tomioka, Y., Ozaki, K., Takeda, K., Suyama, H., Yamamoto, S., Takakuwa, H., Morimatsu, M., Uede, T. and Ono, E. 2017. Comparison of the antiviral potential among soluble forms of herpes simplex virus type-2 glycoprotein D receptors, herpes virus entry mediator A, nectin-1 and nectin-2, in transgenic mice. Journal of General Virology 98: 1815-1822.

Saito, M., Yamamoto, S., Ozaki, K., Tomioka, Y., Suyama, H., Morimatsu, M., Nishijima, K.-i., Yoshida, S.-i. and Ono, E. 2016. A soluble form of Siglec-9 provides a resistance against Group B Streptococcus (GBS) infection in transgenic mice. Microbial Pathogenesis 99: 106-110.

Ochiai, K., Morimatsu, M., Kato, Y., Ishiguro-Oonuma, T., Udagawa, C., Rungsuriyawiboon, O., Azakami, D., Michishita, M., Ariyoshi, Y., Ueki, H., Nasu, Y., Kumon, H., Watanabe, M. and Omi, T. 2016. Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity. Oncotarget 7: 3273-3286.

Fujimoto, Y., Tomioka, Y., Takakuwa, H., Uechi, G.-I., Yabuta, T., Ozaki, K., Suyama, H., Yamamoto, S., Morimatsu, M., Mai, L. Q., Yamashiro, T., Ito, T., Otsuki, K. and Ono, E. 2016. Cross-protective potential of anti-nucleoprotein human monoclonal antibodies against lethal influenza A virus infection. Journal of General Virology 97: 2104-2116.

Elkhateeb, E., Tag-El-Din-Hassan, H. T., Sasaki, N., Torigoe, D., Morimatsu, M. and Agui, T. 2016. The role of mouse 2 ',5 '-oligoadenylate synthetase 1 paralogs. Infection Genetics and Evolution 45: 393-401.

Yoshikawa, Y., Morimatsu, M., Ochiai, K., Ishiguro-Oonuma, T., Wada, S., Orino, K. and Watanabe, K. 2015. Reduced canine BRCA2 expression levels in mammary gland tumors. BMC Vet Res 11: 159.

Ochiai, K., Ishiguro-Oonuma, T., Yoshikawa, Y., Udagawa, C., Kato, Y., Watanabe, M., Bonkobara, M., Morimatsu, M. and Omi, T. 2015. Polymorphisms of canine BRCA2 BRC repeats affecting interaction with RAD51. Biomedical Research-Tokyo 36: 155-158.

Kato, Y., Ochiai, K., Michishita, M., Azakami, D., Nakahira, R., Morimatsu, M., Ishiguro-Oonuma, T., Yoshikawa, Y., Kobayashi, M., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M. and Omi, T. 2015. Molecular cloning of canine co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) and investigation of its ability to suppress androgen receptor signalling in androgen-independent prostate cancer. Veterinary Journal 206: 143-148.

Ishiguro-Oonuma, T., Ochiai, K., Hashizume, K. and Morimatsu, M. 2015. The role of IFN-gamma in regulating Nfkbiz expression in epidermal keratinocytes. Biomedical Research-Tokyo 36: 103-107.

Ishiguro-Oonuma, T., Ochiai, K., Hashizume, K., Iwanaga, T. and Morimatsu, M. 2015. Nfkbiz regulates the proliferation and differentiation of keratinocytes. Jpn J Vet Res 63: 107-114.

Abou-Elnaga, A. F., Torigoe, D., Fouda, M. M., Darwish, R. A., Abou-Ismail, U. A., Morimatsu, M. and Agui, T. 2015. Identification of multiple genetic loci in the mouse controlling immobility time in the tail suspension and forced swimming tests. Japanese Journal of Veterinary Research 63: 53-62.

Yoshimura, A., Musashi, M., Kaneko, T., Ohnishi, S., Orito, C., Kawahara, Y., Hashino, S., Morimatsu, M., Konno, S., Arikawa, J., Ishii, T., Sawamura, M. and Ueda, I. 2014. [Sensitization to laboratory animal allergens among students and researchers exposed to laboratory rodents in Hokkaido university]. Arerugi 63: 1132-1139.

Tomioka, Y., Morimatsu, M., Nishijima, K.-i., Usui, T., Yamamoto, S., Suyama, H., Ozaki, K., Ito, T. and Ono, E. 2014. A soluble form of Siglec-9 provides an antitumor benefit against mammary tumor cells expressing MUC1 in transgenic mice. Biochemical and Biophysical Research Communications 450: 532-537.

Tanaka, T., Kasai, H., Yamashita, A., Okuyama-Dobashi, K., Yasumoto, J., Maekawa, S., Enomoto, N., Okamoto, T., Matsuura, Y., Morimatsu, M., Manabe, N., Ochiai, K., Yamashita, K. and Moriishi, K. 2014. Hallmarks of Hepatitis C Virus in Equine Hepacivirus. Journal of Virology 88: 13352-13366.