Nanomedicine & Immunotherpaeutics Engineering Lab.
Nanomedicine & Immunotherpaeutics Engineering Lab.
Research Approach
The NITE Lab at Dankook University develops nanomedicine platforms for immunotherapy. We engineer various types of nanomaterials including cell-derived vesicles, polymeric nanoparticles, and lipid nanoparticles to target immune and organ-specific cells and precisely modulate immune responses for tissue regeneration and cancer therapy.
By tuning targeting ability—tropism, surface chemistry and affinity— and payloads, we leverage context-dependent immune suppression or activation to restore tissue function.
We apply these platforms to treat myocardial infarction and other degenerative conditions (skin, spinal cord, bone) and to cancer immunotherapy in animal models.
Representative Works
Cell-derived nanovesicles engineered with iron oxide nanoparticles / macrophage membrane targeting ischemic diseases (myocardial infarction and spinal cord injury)
Drug-releasing polymeric nanoparticles that can selectively eliminate senescent cells in myocardial infarction
Lipid nanoparticles for targeting and modulating T cells for cardiac immunotherapy