West China Union University (WCUU) was founded in 1910 as a unique "union venture" between four distinct mission boards: American Baptist, American Methodist, Canadian Methodist, and British Friends (Quakers).
WCUU earned this nickname from the local people after the Episcopal Church joined the administration in 1918.
WCUU utilized a unique blend of Western interiors and Chinese exteriors to navigate anti-Christian sentiment and respect local culture.
During the Second Sino-Japanese War, WCUU hosted refugee universities like Yenching and Nanking to form the famous "Big Five" on the Huaxi Dam, becoming a critical center for education in the "Great Rear Area".
In 1952, the university was restructured; its medical schools became the foundation for today's West China Medical University (West China Medical Center), while its Arts and Science departments were merged into Sichuan University.