Yamamoto S, Saito Y*, Sato T, Nakano S, Kasseki D, Nagao A, Miura N, Nagaoka K, Kita A, Miyajima M, Ijima S, Taniguchi K, Niida A, Chikenji TS*. HLA class I-downregulated senescent epidermal basal cells orchestrate skin pathology in cutaneous lupus erythematosus. Arthritis Rheumatol. (2025) doi: 10.1002/art.43244. Epub ahead of print. New
Saito Y, Yamamoto S & Chikenji TS*. Role of cellular senescence in inflammation and regeneration. Inflamm Regener 44, 28 (2024). https://doi.org/10.1186/s41232-024-00342-5. New
Ijima S, Saito Y*, Yamamoto S, Nagaoka K, Iwamoto T, Kita A, Miyajima M, Sato T, Miyazaki A, Chikenji TS*. Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus. Immun Ageing. 2023 Dec 5;20(1):72. doi: 10.1186/s12979-023-00400-5. PMID: 38053160; PMCID: PMC10696703.
Ijima S, Saito Y*, Nagaoka K, Yamamoto S, Sato T, Miura N, Iwamoto T, Miyajima M, Chikenji TS*Fisetin reduces the senescent tubular epithelial cell burden and also inhibits proliferative fibroblasts in murine lupus nephritis. Front Immunol., 2022 Nov., doi.org/10.3389/fimmu.2022.960601
Saito Y, Miyajima M, Yamamoto S, Miura N, Sato T, Kita A, Ijima S, Fujimiya M, Chikenji TS*. Intrathecal Injection of Mesenchymal Stromal Cell Cultured on 3D Fiber Ameliorates Multiple Organ Damage in Murine Lupus. Stem Cells Transl Med. 2022 Jun 11(6):644-658. doi: 10.1093/stcltm/szac021. プレスリリース
Kita A, Saito Y*, Miura N, Miyajima M, Yamamoto S, Sato T, Yotsuyanagi T, Fujimiya M, Chikenji TS*. Altered regulation of mesenchymal cell senescence in adipose tissue promotes pathological changes associated with diabetic wound healing. Commun Biol., 2022 Apr 5;5(1):310. doi: 10.1038/s42003-022-03266-3. プレスリリース
Saito Y, Miyajima M, Yamamoto S, Sato T, Miura N, Fujimiya M, Chikenji TS*. Accumulation of Senescent Neural Cells in Murine Lupus With Depression-Like Behavior. Front Immunol., 2021 Nov., doi.org/10.3389/fimmu.2021.692321 プレスリリース
Saito Y, Chikenji TS*. Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regeneration, and Therapeutics. Front Pharmacol. 2021 Sep doi.org/10.3389/fphar. 2021.739510
Saito Y, Chikenji TS*, Matsumura T, Nakano M, Fujimiya M. Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors. Nat Commun. 2020 Feb 14;11(1):889. doi: 10.1038/s41467-020-14734-x. PMID: 32060352; PMCID: PMC7021787.
プレスリリース
Chikenji TS*, Saito Y, Konari N, Nakano M, Mizue Y, Otani M, Fujimiya M. p16INK4A-expressing mesenchymal stromal cells restore the senescence- clearance-regeneration sequence that is impaired in chronic muscle inflammation. EBioMedicine. 2019 Jun;44:86-97. doi: 10.1016/j.ebiom.2019.05.012. Epub 2019 May 23. PMID: 31129096; PMCID: PMC6604166.
プレスリリース
Matsumura T, Saito Y, Suzuki T, Teramoto A, Ozasa Y, Yamashita T, Fujimiya M, Saito-Chikenji T*. Phosphorylated Platelet-Derived Growth Factor Receptor- Positive Cells With Anti-apoptotic Properties Accumulate in the Synovium of Patients With Rheumatoid Arthritis. Front Immunol. 2019 Feb 15;10:241. doi: 10.3389/fimmu.2019.00241. PMID: 30828336; PMCID: PMC6384265.
Saito Y*, Chikenji TS, Takata Y, Kamiya T, Uchiyama E. Can an insole for obese individuals maintain the arch of the foot against repeated hyper loading? BMC Musculoskelet Disord. 2019 Oct 11;20(1):442. doi: 10.1186/s12891-019-2819-2. PMID: 31604431; PMCID: PMC6790017.