The International Schools Activities Association (ISAA) is a high school athletic conference that brings together schools from Europe, Africa, and the Middle East. Cairo American College (CAC) is proud to be a member of this dynamic conference, which emphasizes not only competitive athletics but also cultural exchange, sportsmanship, and student growth.

Each varsity sports season at CAC culminates with an end-of-season ISAA tournament, typically hosted by one of the member schools at an exciting destination. These tournaments provide student-athletes with the chance to test their skills at a high level of competition, while also experiencing new environments and connecting with peers from other international schools.

The ISAA conference covers a range of sports across three main seasons, with each season concluding in a championship tournament that highlights the best of international school athletics.