Publications
Link to all publications
PubMed link:
https://pubmed.ncbi.nlm.nih.gov/?term=Indranil%20Malik&sort=pubdate
Google Scholar:
https://scholar.google.com/citations?user=_XCPOL4AAAAJ&hl=en&oi=ao
Selected Publications
Malik I, Tseng YJ, Wieland CM, Green KM, Zheng K, Calleja K, Todd PK.
Neurobiol Dis. 2023 Jun 22;184:106212. doi: 10.1016/j.nbd.2023.106212.
SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.
Malik I, Tseng YJ, Wright SE, Zheng K, Ramaiyer P, Green KM, Todd PK.
EMBO Mol Med. 2021 Nov 8;13(11):e14163. doi: 10.15252/emmm.202114163.
Molecular mechanisms underlying nucleotide repeat expansion disorders.
Malik I*, Kelley CP*, Wang ET, Todd PK.
Nat Rev Mol Cell Biol. 2021 Sep;22(9):589-607. doi: 10.1038/s41580-021-00382-6.
Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.
Malik I, Qiu C, Snavely T, Kaplan CD.
Nucleic Acids Res. 2017 May 5;45(8):4431-4451. doi: 10.1093/nar/gkx037.
Barnes CO*, Calero M*, Malik I, Graham BW, Spahr H, Lin G, Cohen AE, Brown IS, Zhang Q, Pullara F, Trakselis MA, Kaplan CD, Calero G.
Mol Cell. 2015 Jul 16;59(2):258-69. doi: 10.1016/j.molcel.2015.06.034.
All Publications
After joining IITH
Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats (2024). Tseng YJ, Krans A, Malik I, Deng X, Yildirim E, Ovunc S, Tank EMH, Jansen-West K, Kaufhold R, Gomez NB, Sher R, Petrucelli L, Barmada SJ, Todd PK#. Nucleic Acids Res. 2024 Feb 27:gkae137. doi: 10.1093/nar/gkae137. Online ahead of print. PMID: 38412259
Thiolutin has complex effects in vivo but is a direct inhibitor of RNA polymerase II in vitro (2024). Qiu C, Arora P, Malik I, Laperuta AJ, Pavlovic EM, Ugochukwu S, Naik M, Kaplan CD#. Nucleic Acids Res. 2024 Jan 12:gkad1258. doi: 10.1093/nar/gkad1258. Online ahead of print. PMID: 38214235
"Deoxy" to be or "Desoxy" not to be-a century-old tale in the history of DNA nomenclature (2024). Sharma G#, Chodvadiya J, Malik I. J Bacteriol. 2024 Jan 31:e0040123. doi: 10.1128/jb.00401-23. Online ahead of print. PMID: 38294238 Free article.
Before joining IITH
1. Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS (2023). Indranil Malik, Yi-Ju Tseng, Clare Wieland, Katelyn M. Green, Kristina Zheng, Katyanne Calleja and Peter K. Todd#. Neurobiol Dis. 2023 Jun 22;184:106212. doi: 10.1016/j.nbd.2023.106212.
2. Identification of PSMB5 as a genetic modifier of Fragile X-Associated Tremor/Ataxia Syndrome (2022). Ha Eun Kong, Junghwa Lim, Alexander Linsalata, Yunhee Kang, Indranil Malik, Emily G Allen, Lisa Shubeck, Rich Johnston, Yanting Huang, Michael E Zwick, Zhaohui Qin, Thomas S Wingo, Michael P Epstein, David J Cutler, Peter K Todd, Stephanie Sherman, Stephen T Warren, Peng Jin# (2022). Proc Natl Acad Sci USA. 2022 May 31;119(22):e2118124119.
3. Non-canonical initiation factors modulate repeat-associated non-AUG translation (2022). Katelyn M Green, Shannon L Miller, Indranil Malik, Peter K Todd#. Hum Mol Genet. 2022 Feb 26:ddac021.
4. SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity (2021). Indranil Malik, Yi-Ju Tseng*, Shannon E. Wright*, Kristina Zheng, Prithika Ramaiyer, Katelyn M. Green, Peter K. Todd#. EMBO Mol Med. 2021 Nov 8;13(11):e14163.
5. Molecular mechanisms underlying nucleotide repeat expansion disorders (2021). Indranil Malik*, Chase P. Kelley*, Eric T. Wang# and Peter K. Todd#. Nature Reviews Molecular Cell Biology. 2021 Sep;22(9):589-607. [Cover Article]
6. Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae (2020). Chenxi Qiu*, Huiyan Jin*, Irina Vvedenskaya, Jordi Abante Llenas, Tingting Zhao, Indranil Malik, Alex M Visbisky, Scott L Schwartz, Ping Cui, Pavel Čabart, Kang Hoo Han, William K M Lai, Richard P Metz, Charles D Johnson, Sing-Hoi Sze, B Franklin Pugh, Bryce E Nickels, Craig D Kaplan#. Genome Biol. 2020 Jun 2;21(1):132.
7. Organismal benefits of transcription speed control at gene boundaries (2020). Xueyuan Leng, Maxim Ivanov, Peter Kindgren, Indranil Malik, Axel Thieffry, Peter Brodersen, Albin Sandelin, Craig D Kaplan, Sebastian Marquardt#. EMBO Rep. 2020 Apr 3;21(4):e49315.
8. Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo (2017). Indranil Malik, Chenxi Qiu, Thomas Snavely, Craig D Kaplan#. Nucleic Acids Res. 2017 May 5;45(8): 4431-4451.
9. Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble (2015). Christopher O Barnes*, Monica Calero*, Indranil Malik, Brian W Graham, Henrik Spahr, Guowu Lin, Aina E Cohen, Ian S Brown, Qiangmin Zhang, Filippo Pullara, Michael A Trakselis, Craig D Kaplan, Guillermo Calero#. Mol Cell. 2015 Jul 16;59(2):258-69.
10. Green Chemistry. Reaction of Elemental Phosphorus (P4) and Elemental Sulfur with Protonodonor Reagents: New Methods for the Synthesis of Ammonium Salts of S,S′-Dialkyltetrathiophosphoric Acids and Octathiotetraphosphetane (2013). Elvira S Batyeva, Elena K Badeeva#, Elena V Platova, Aidar T Gubaidullin, Nikki Porch, Leslie Edwards, Indranil Malik, Liliya V Frolova, Igor V Magedov, Snezna Rogelj, Oleg G Sinyashin. Heteroatom. Chem., 2013, 24, 163. https://doi.org/10.1002/hc.21077
11. Systematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetine (2012). Scott A Hoose, Camille Duran, Indranil Malik, Shabnam Eslamfam, Samantha C Shasserre, S Sabina Downing, Evelyn M Hoover, Katherine E Dowd, Roger Smith 3rd, Michael Polymenis#. PLoS One. 2012;7(5):e36503.
12. Multicomponent Synthesis of 2,3-Dihydrochromeno[4,3-d]pyrazolo[3,4-b]pyridine-1,6-diones: A Novel Heterocyclic Scaffold with Antibacterial Activity (2011). Liliya V Frolova, Indranil Malik, Pavel Y Uglinskii, Snezna Rogelj, Alexander Kornienko, Igor V Magedov#. Tetrahedron Lett. 2011 Dec 7;52(49):6643-6645.
13. Unprecedented C-2 arylation of indole with diazonium salts: Syntheses of 2,3-disubstituted indoles and their antimicrobial activity (2011). Seth Daly, Kathryn Hayden, Indranil Malik, Nikki Porch, Hong Tang, Snezna Rogelj, Liliya V Frolova, Katrina Lepthien, Alexander Kornienko, Igor V Magedov#. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4720-3.
14. One-pot multicomponent synthesis of diversely substituted 2-aminopyrroles. A short general synthesis of rigidins A, B, C, and D (2011). Liliya V Frolova, Nikolai M Evdokimov, Kathryn Hayden, Indranil Malik, Snezna Rogelj, Alexander Kornienko, Igor V Magedov#. Org Lett. 2011 Mar 4;13(5): 1118-21.