Dr. Sritama De Sarkar

Assistant Professor

Dept. of Biotechnology

Brainware University

srs.bt@brainwareuniversity.ac.in

Contact: 8240073061

Qualifications

  • BSc in Microbiology, University of Calcutta

  • MSc in Microbiology, University of Calcutta

  • PhD in Microbiology, University of Calcutta

Research interests

Cell biology, Immunology, Tissue culture, Metabolomics

Publications

1. De Sarkar S, Sarkar D, Sarkar A, Dighal A, Chakrabarti S, Staniek K, Gille L, Chatterjee M. The leishmanicidal activity of artemisinin is mediated by cleavage of the endoperoxide bridge and mitochondrial dysfunction. Parasitology 2019; 146: 511-20.

2. De Sarkar S, Sarkar D, Sarkar A, Dighal A, Staniek K, Gille L, Chatterjee M. Berberine chloride mediates its antileishmanial activity by inhibiting Leishmania mitochondria. Parasitol Res 2019; 118: 335-45.

3. Geroldinger G, Tonner M, Quirgst J, Walter M, De Sarkar S, Machín L, Monzote L, Stolze K, Catharina Duvigneau J, Staniek K, Chatterjee M, Gille L. Activation of artemisinin and heme degradation in Leishmania tarentolae promastigotes: A possible link. Biochem Pharmacol. 2019 Nov 29:113737.

4. Geroldinger G, Tonner M, Fudickar W, De Sarkar S, Dighal A, Monzote L, Staniek K, Linker T, Chatterjee M, Gille L. Activation of Anthracene Endoperoxides in Leishmania and Impairment of Mitochondrial Functions. Molecules 2018; 23. pii: E1680.

5. Monzote L, Geroldinger G, Tonner M, Scull R, De Sarkar S, Bergmann S, Bacher M, Staniek K, Chatterjee M, Rosenau T, Gille L. Interaction of ascaridole, carvacrol, and caryophyllene oxide from essential oil of Chenopodium ambrosioides L. with mitochondria in Leishmania and other eukaryotes. Phytother Res 2018; 32: 1729-40.

6. Mitra S, De Sarkar S, Pradhan A, Pati AK, Pradhan R, Mondal D, Sen S, Ghosh A, Chatterjee S, Chatterjee M. Levels of oxidative damage and proinflammatory cytokines are enhanced in patients with active vitiligo. Free Radic Res 2017; 51: 986-94.

7. De S, Manna A, Kundu S, De Sarkar S, Chatterjee U, Sen T, Chattopadhyay S, Chatterjee M. Allylpyrocatechol Attenuates CollagenInduced Arthritis via Attenuation of Oxidative Stress Seco ndary to Modulation of the MAPK, JAK/STAT, and Nrf2/HO-1 Pathways. J Pharmacol Exp Ther 2017; 360: 249-259.

8. Manna A*, De Sarkar S*, De S, Bauri AK, Chattopadhyay S, Chatterjee M. Impact of MAPK and PI3K/AKT signaling pathways on Malabaricone-A induced cytotoxicity in U937, a histiocytic lymphoma cell line. Int Immunopharmacol 2016; 39: 34-40. [*joint 1st authors]

9. Manna A, De Sarkar S, De S, Bauri AK, Chattopadhyay S, Chatterjee M. The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance. Phytomedicine 2015; 22: 713-23.

10. Mukhopadhyay D, Das NK, De Sarkar S, Manna A, Ganguly DN, Barbhuiya JN, Maitra AK, Hazra A, Chatterjee M. Evaluation of serological markers to monitor the disease status of Indian post kala-azar dermal leishmaniasis. Trans R Soc Trop Med Hyg 2012; 106: 668-76

Experience

  • Asst. Professor in Dept. of Biotechnology, Brainware University-February 2021-Present

  • Industry- NA

  • Others: Worked in an ICMR funded multi-centric project for 1 year, Worked in a project funded by Chirugupati Technologies Pvt. Ltd. India for 6 months

Awards

  • 2017: DST SERB, Govt. of India, 6th World Congress on Leishmaniasis, Toledo, Spain.

  • 2017: OeAD (Österreichische Austauschdienst)-Gesellschaft mit beschränkter Haftung, Austrian Agency for International Cooperation in Education and Research, student fellowship, Fellowship for carrying out collaborative research work under the DST-OEAD, India-Austria Academic collaboration in the laboratory of Prof. Lars Gille, Dept. of Biomedical Sciences, Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna.

  • 2017: Travel grant, Immunology Foundation, India for attending the 6th World Congress on Leishmaniasis, Toledo, Spain.

  • 2016: Travel grant, 13th FIMSA Advanced Immunology Course 2016, PGIMER, Chandigarh.

  • 2014: 2nd prize, Poster presentation, 7th Annual The Cytometry Society Meeting & 15th Indo-US Clinical Cytometry Workshop 2014, AIIMS, Delhi