Wei-Le Wang, PhD

Dr. Wei-Le Wang received his BSc from the Department of Chemistry, National Taiwan University in 2007. After obtaining a Master’s degree in Immunology from the National Taiwan University in 2009, he continued his training under the guidance of Dr. Mark Boldin at City of Hope and acquired his Ph.D. in 2019. Dr. Wang then conducted his postdoctoral training in the laboratory of Dr. Marco Colonna at Washington University in St. Louis from 2019 to 2022. In October 2022, he established his lab at the Institute of Molecular Biology Academia Sinica.

Dr. Wang’s research focuses on immune regulations. In this field, his contributions encompass characterization of a hematopoietic lineage-specific microRNA miR-142 in the control of adaptive immune responses, including B cell development and function, regulatory T (Treg) cell-mediated immune tolerance. Through analysis of immune cells in the tissue barriers, Dr. Wang and colleagues identified novel niches at CNS borders for B cell lymphopoiesis and a novel eosinophil subset that is unique to the small intestine and modulates the type 2 immune responses.