Publications

2025

59.

58. Zainab Amin and Jeetender Chugh* NMR insights into stress-induced modulation of the monomer-dimer equilibrium in a small Heat Shock Protein

Magnetic Resonance in Chemistry; 2025, In Press (manuscript accepted)

57. Shreyada N. Save,1 Soumya Swastik Sahoo,1 Kalyani Ananthamohan, Saleem Yousf, Pratishtha Singh, Osama Aazmi, Jeetender Chugh, and Shilpy Sharma* Mapping the metabolic perturbations associated with palmitate-induced oxidative stress and development of insulin resistance in skeletal muscle cells

Biophysical Chemistry; 2025, 326, 107490 1Authors contributed equally

56. Soumya Swastik Sahoo, Shreyada N. Save, Shantanu Madiwale, Shilpy Sharma*, and Jeetender Chugh* Visualization of early and late molecular events associated with the development of Type I Diabetes using NMR spectroscopy

Journal of Proteome Research; 2025, 24, 8, 4202–4214

55. Osama Aazmi, Akshit Rajendra Aswale, Leo Saju, and Jeetender Chugh* Investigating the role of conformational heterogeneity in FUS-RRM fibrillation

International Journal of Biological Macromolecules; 2025, 311, Part 3, Article 143954

2024

54. Firdousi Parvez,1 Zainab Amin,1 Devika Sangpal,1 and Jeetender Chugh* Role of pH in Modulating RNA-Protein Interactions in TRBP2-dsRBD2: An Interplay between Conformational Dynamics and Electrostatic Interactions

The Journal of Physical Chemistry B; 2024,128(51), 12698-12709  1Authors contributed equally (Front cover article)

53. Arya R. Naik,1 Shreyada N. Save,1 Soumya S Sahoo,1 Saurabh S. Yadav, Ashutosh Kumar, Jeetender Chugh, Shilpy Sharma* Metabolic Perturbations associated with hIAPP-induced insulin resistance in Skeletal Muscles: Implications to the Development of Type 2 Diabetes

International Journal of Biochemistry and Cell Biology; 2024, 176, 106665 1Authors contributed equally

52. Saleem Yousf, Hitender S. Batra, Rakesh M Jha, Devika M Sardesai, Kalyani Ananthamohan, Jeetender Chugh*, and Shilpy Sharma* Identification of potential serum biomarkers associated with HbA1c levels in Indian Type2 Diabetic subjects using NMR-based metabolomics 

Clinica Chimica Acta; 2024, 557, 117857

51.  Aseem Palande, Saniya Patil, Anjali Veeram, Soumya Swastik Sahoo, Tejan Lodhiya, Pankaj Maurya, Balaji M, Jeetender Chugh, and Raju Mukherjee* Proteomic analysis of the Mycobacterium tuberculosis outer membrane for potential implications in uptake of small molecules 

ACS Infectious Diseases; 2024, 10(3), 890-906

50. Firdousi Parvez, Devika Sangpal, Harshad Paithankar, Zainab Amin, and Jeetender Chugh* Differential conformational dynamics in two type-A RNA-binding domains drive the double-stranded RNA recognition and binding 

BioRxiv; 2023, https://doi.org/10.1101/2023.08.06.552166

eLife; 2024, 13:RP94842

2023

49. Saleem Yousf*, Javid A Malla, Devika M Sardesai, Shilpy Sharma, Pinaki Talukdar, and Jeetender Chugh* Mapping metabolic perturbations induced by glutathione activatable synthetic ion channels in human breast cancer cells 

Journal of Pharmaceutical and Biomedical Analysis; 2023, 235, 115605

2022

48. Avdhoot Datar, Harshad Paithankar, Pranab Deb, Jeetender Chugh*, Sayan Bagchi*, Arnab Mukherjee*, and Anirban Hazra* Water-controlled keto-enol tautomerization of a prebiotic nucleobase 

The Journal of Physical Chemistry B; 2022, 126(31), 5735-5743

47. Harshad Paithankar1, Guneet Singh Tarang1, Firdousi Parvez1, Aniket Marathe, Manali Joshi, and Jeetender Chugh* Inherent conformational plasticity in dsRBDs enables interaction with topologically distinct RNAs 

Biophysical Journal; 2022, 121(6), 1038-1055 1Authors contributed equally

2021

46. Abhishek Mondal, Javid Ahmad Malla, Harshad Paithankar, Shilpy Sharma, Jeetender Chugh, and Pinaki Talukdar* A Pyridyl-Linked Benzimidazolyl Tautomer Facilitates Prodigious H+/Cl– Symport through a Cooperative Protonation and Chloride Ion Recognition 

Organic Letters; 2021, 23(15), 6131-6136

45. Rishabh Gupta, Harshad Paithankar, Jeetender Chugh*, and R Boomishankar* Construction of Entropically Favored Supramolecular Metal-Ligand Trimeric Assemblies Supported by Flexible Pyridylamino-P(V) Scaffolds 

Inorganic Chemistry; 2021, 60(14), 10468-10477

44. Saleem Yousf and Jeetender Chugh* Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry: Complementary Approaches to Analyze the Metabolome 

Journal of Endocrinology and Reproduction; 2020, 24(1), 21-30

2020

43. Richa Dubey, Shruti Kulkarni, Sarath Dantu, Rajlaxmi Panigrahi, Devika Sardesai, Nikita Malik, Jhankar Acharya, Jeetender Chugh, Shilpy Sharma, and Ashutosh Kumar* Myricetin protects pancreatic ?-cells from human Islet Amyloid Polypeptide (hIAPP) induced cytotoxicity and restores islet function 

Biological Chemistry; 2020, 402(2), 179-194

42. Shahaji R Gaikwad, Ketan Patel, Satej S Deshmukh, Nilesh R Mote, Rajkumar S Birajdar, Satish P Pandole, Jeetender Chugh, and Samir Hujur Chikkali* Insertion of 1,1-Disubstituted Difunctional Olefins and Ethylene Polymerization 

ChemPlusChem; 2020, 85(6), 1200-1209

41. Niraja V Bapat,1, Harshad Paithankar1, Jeetender Chugh*, and Sudha Rajamani* NMR analysis of nucleotide pi-stacking in prebiotically relevant crowded environment 

BioRxiv; 2019, doi: https://doi.org/10.1101/655423; 

Nature Communications Chemistry; 2020, 3, Article Number 51 1Authors contributed equally

40. Sagar S Datir*,1, Saleem Yousf1, Shilpy Sharma, Mohit Koshle, Ameeta Ravikumar, and Jeetender Chugh* Cold storage reveals distinct metabolic perturbations in processing and non-processing cultivars of potato (Solanum tuberosum L.) 

BioRxiv; 2019, doi: https://doi.org/10.1101/661611; 

Nature Scientific Reports; 2020, 10, Article No. 6268 1Authors contributed equally

39. Madhuri Vangala*, Saleem Yousf, Jeetender Chugh, and Srinivas Hotha Solid-Phase Synthesis of Clickable Psicofuranose Glycocarbamates and Application of Their Self-Assembled Nanovesicles for Curcumin Encapsulation 

ChemistrySelect; 2020, 5(9), 2672-2677

2019

38. Harshad Paithankar and Jeetender Chugh* Role of protein dynamics in enthalpy-driven recognition of topologically distinct dsRNAs by dsRBDs 

BioRxiv; 2019, doi: https://doi.org/10.1101/862326

37. Harshad Paithankar and Jeetender Chugh* Characterization of conformational dynamics at microsecond timescale in the RNA-binding regions of dsRNA-binding domains 

BioRxiv; 2019, doi: https://doi.org/10.1101/797449

36. Arshad Rizvi1, Saleem Yousf1, Kannan Balakrishnanan, Harish K Dubey, Shekhar C Mande, Jeetender Chugh*, and Sharmistha Banerjee* Metabolomics studies to decipher stress responses in Mycobacterium smegmatis point to a putative pathway of methylated amines biosynthesis 

Journal of Bacteriology; 2019, 201(15), 477-489 1Authors contributed equally

35. Saleem Yousf1, Devika M Sardesai1, Abraham B Mathew, Rashi Khandelwal, Jhankar D Acharya, Shilpy Sharma*, and Jeetender Chugh* Metabolic signatures suggest o-phosphocholine to UDP-N-acetylglucosamine ratio as a potential biomarker for high-glucose and/or palmitate exposure in pancreatic beta-cells 

Metabolomics; 2019, 15(4), Article 55 1Authors contributed equally

2018

34. Harshad Paithankar, Pankaj V Jadhav, Amit S Naglekar, Shilpy Sharma and Jeetender Chugh* 1H, 13C and 15N Resonance Assignment of Domain 1 of Trans-Activation Response Element (TAR) RNA Binding Protein Isoform 1 (TRBP2) and its comparison with that of Isoform 2 (TRBP1) 

Biomolecular NMR Assignments; 2018, 12(1), 189-194

33. Prabhakaran Rajasekar, Swechchha Pandey, Harshad Paithankar, Jeetender Chugh*, Alexander Steiner and Ramamoorthy Boomishankar* Imido-P(V) Trianion Supported Enantiopure Neutral Tetrahedral Pd(II) Cages 

Chemical Communications; 2018, 54(15), 1873-1876

2017

32. Vikash K Ravi, Pralay Santra, Niharika Joshi, Jeetender Chugh, Sachin Singh, Håkan Rensmo, Prasenjit Ghosh* and Angshuman Nag* Origin of Substitution Mechanism for the Binding of Organic Ligands on the Surface of CsPbBr3 Perovskite Nanocubes 

Journal of Physical Chemistry Letters; 2017, 8(20), 4988-4994

31. Saleem Yousf, Nazia Hussain, Shilpy Sharma*, Jeetender Chugh* Identification & Characterization of Secondary Metabolites in the Biological Soup by NMR Spectroscopy 

Applications of NMR Spectroscopy; Bentham Science 2017, Vol 6 (1st edition), Chapter 2, 47-96, edited by Atta-ur-Rahman and M. Iqbal Chaudhary

30. Shilpy Sharma,* Abraham B Mathew and Jeetender Chugh miRNAs: nanomachines that microManage the pathophysiology of Diabetes mellitus 

Advances in Clinical Chemistry; 2017, Vol 82 (1st Edition), Chapter 5, 199-264; edited by Gregory Makowski

2016

29. Chaitanya Mungi, Sachin Kumar Singh, Jeetender Chugh* and Sudha Rajamani* Synthesis of barbituric acid containing nucleotide and its implications for the origin of primitive informational polymers 

Physical Chemistry Chemical Physics; 2016, 18, 20144-20152

2015

28. Michael D. Swanson1, Daniel M. Boudreaux1, Loïc Salmon1, Jeetender Chugh, Harry C. Winter, Jennifer L. Meagher, Sabine André, Paul V. Murphy, Stefan Oscarson, René Roy, Steven King, Mark H. Kaplan, Irwin J. Goldstein, E. Bart Tarbet, Brett L. Hurst, Donald F. Smee, Cynthia de la Fuente, Hans-Heinrich Hoffmann, Yi Xue, Charles M. Rice, Dominique Schols, J. Victor Garcia, Jeanne A. Stuckey, Hans-Joachim Gabius, Hashim M. Al-Hashimi*, and David M. Markovitz* Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity 

Cell; 2015, 163(3), 746-58 1Authors contributed equally

27. Parnika Bhatia, Shikha Raina, Jeetender Chugh and Shilpy Sharma* miRNAs: Early Prognostic Markers for Type 2 Diabetes Mellitus? 

Biomarkers in Medicine; 2015, 9(10), 1025-40

26. Arvind K Gupta, Ashok Yadav, Anant K Srivastava, Kormathmadam R Ramya, Harshad Paithankar, Shyamapada Nandi, Jeetender Chugh*, Ramamoorthy Boomishankar* A Neutral Cluster Cage with a Tetrahedral [PdII12L6] Framework: Crystal Structures and Host-Guest Studies 

Inorganic Chemistry; 2015, 54(7), 3196-3202 (One of the Top 20 most downloaded articles of the month)

25. Jeetender Chugh (Presenting Author) Visualizing Transient Structures in A-site RNA of the Ribosome: New Structures of Known Molecules for Drug Target 

Journal of Proteins and Proteomics; 2015, 6(1), JPP10

2014

24. Xiancheng Zeng, Jeetender Chugh, Anette Casiano, Hashim M Al-Hashimi*, Charlie Brooks III* Flipping of the ribosomal A-site adenines provides basis for tRNA selection 

Journal of Molecular Biology; 2014, 426(19), 3201-3213

23. Jeetender Chugh* Determining Transient Nucleic Acid Structures by NMR 

Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications; Springer 2014, 181-198, edited by Volker A. Erdmann, Wojciech T. Markiewicz and Jan Barciszewski

2013

22. Hashim M Al-Hashimi (Presenting Author), Katja Petzold, Jeetender Chugh, Anthony M Mustoe, Elizabeth A Dethoff and Charlie Brooks III Predictive Understanding of RNA Dynamic Behavior: Bringing Order to Disorder 

The FASEB Journal; 2013, 27(96.1) (Conference Abstract)

2012

21. Elizabeth A Dethoff1, Katja Petzold1, Jeetender Chugh1, Anette Casiano, and Hashim M Al-Hashimi* Visualizing Transient Low Populated Structures of RNA 

Nature; 2012, 491(7426), 724-728 (Featured as News of the Week in C&EN; 2012, 90(42), 10) 1Authors contributed equally

20. Elizabeth A Dethoff1, Jeetender Chugh1, Anthony M Mustoe and Hashim M Al-Hashimi* Functional Complexity and Regulation through RNA Dynamics 

Nature; 2012, 482(7385), 322-330 (Featured as an Insight Article) 1Authors contributed equally

2011

19. Jeetender Chugh (Presenting Author), Anette Casiano-Negroni and Hashim M Al-Hashimi* NMR Dissection of the Detailed Mechanism for Antibiotic Binding to A-site RNA 

Biophysical Journal; 2011, 100(3), Supplemental 1, 603a (Conference Abstract)

18. Jameson R Bothe, Evgenia N Nikolova, Catherine D Eichhorn, Jeetender Chugh, Alexandar L. Hansen, and Hashim M. Al-Hashimi* Characterizing RNA Dynamics at Atomic Resolution using Solution-State NMR Spectroscopy 

Nature Methods; 2011, 8(11), 919-931

2010

17. Benjamin C Buer, Jeetender Chugh, Hashim M Al-Hashimi and E Neil G Marsh* Using fluorine NMR to probe the interaction of membrane-active peptides with the lipid bilayer 

Biochemistry; 2010, 49(27), 5760-5765

16. Ramakrishna V Hosur* and Jeetender Chugh NMR advances towards the structural characterization of large protein assemblies 

Journal of Indian Chemical Society; 2010, 87, 53-63

2009

15. Ramakrishna V Hosur* and Jeetender Chugh NMR of large protein assemblies 

Future Directions of NMR (INSA Platinum Jubilee Volume); Springer 2009, edited by Prof. C. L. Kheterpal, Prof. Anil Kumar and Prof. K. V. Ramanathan

14. Dinesh Kumar1, Jeetender Chugh1 and Ramakrishna V Hosur* Generation of Ser/Thr check points in HN(C)N spectra 

Journal of Chemical Sciences (Indian Academy of Sciences); 2009, 121(6), 955-964 1Authors contributed equally

13. Dinesh Kumar1, Jyoti R Misra1, Ashutosh Kumar, Jeetender Chugh, Shilpy Sharma and Ramakrishna V Hosur* NMR Derived Solution Structure of SUMO from Drosophila melanogaster (dSmt3) 

Proteins: Structure, Functions and Bioinformatics; 2009, 75(4), 1046-1050 1Authors contributed equally

12. Dinesh Kumar, Jeetender Chugh, Shilpy Sharma and Ramakrishna V Hosur* Conserved structural and dynamics features in the denatured states of drosophila SUMO, human SUMO and Ubiquitin proteins: implications to sequence-folding paradigm 

Proteins: Structure, Function and Bioinformatics; 2009, 76(2), 387-402

11. Jeetender Chugh1, Shilpy Sharma1 and Ramakrishna V Hosur* Comparison of NMR structural and dynamics featured of urea and guanidine-denatured states of GED 

Archives of Biochemistry and Biophysics; 2009, 481(2), 169-176 1Authors contributed equally

10. Jeetender Chugh1, Shilpy Sharma1, Dinesh Kumar and Ramakrishna V Hosur* 1H, 15N, 13C resonance assignment of 9.7 M urea-denatured state of the GTPase effector domain (GED) of dynamic 

Biomolecular NMR Assignments; 2009, 3(1), 13-16 1Authors contributed equally

2008

9. Jeetender Chugh1, Shilpy Sharma1 and Ramakrishna V Hosur* Equilibrium Refolding Transitions driven by TFE and by Gdn-HCl dilution are similar in GED: Implications to Sequence Self-Association Paradigm 

Biochemistry; 2008, 47(49), 12945-12953 1Authors contributed equally

8. Jeetender Chugh and Ramakrishna V Hosur* Spectroscopic labeling of A, S/T in the 1H-15N HSQC spectrum of uniformly (15N-13C) labeled proteins 

Journal of Magnetic Resonance; 2008, 194(2), 289-294

7. Jeetender Chugh1, Shilpy Sharma1, Dinesh Kumar, Jyoti R Misra and Ramakrishna V Hosur* Effect of a single point mutation on the stability, residual structure and dynamics in the denatured state of GED: relevance to self-assembly 

Biophysical Chemistry; 2008, 137(1), 13-18 1Authors contributed equally

6. Jeetender Chugh, Shilpy Sharma and Ramakrishna V Hosur* NMR Insights into a megadalton-size Protein Self-Assembly 

Protein Science (Accelerated Communication); 2008, 17(8), 1319-1325

5. Jeetender Chugh, Dinesh Kumar and Ramakrishna V Hosur* Tuning the HNN Experiment: Generation of Serine-Threonine check points 

Journal of Biomolecular NMR; 2008, 40(2), 145-152

4. Dinesh Kumar, Ashutosh Kumar, Jyoti Ranjan Misra, Jeetender Chugh, Shilpy Sharma and Ramakrishna V Hosur* 1H, 15N, 13C resonance assignments of folded and 8 M urea-denatured state of SUMO from Drosophila melanogaster 

Biomolecular NMR Assignments; 2008, 2(1), 13-15

2007

3. Jeetender Chugh, Shilpy Sharma and Ramakrishna V Hosur* Pockets of Short Range Transient Order and Topological Heterogeneity in Guanidine-Denatured State Ensemble of GED of Dynamin 

Biochemistry; 2007, 46(42), 11819-11832

2006

2. Jeetender Chugh, Amarnath Chatterjee, Ashutosh Kumar, Ram K Mishra, Rohit Mittal and Ramakrishna V Hosur* Structural Characterization of the Large Soluble Oligomers of the GTPase Effector Domain of Dynamin 

FEBS Journal; 2006, 273(2), 388-97

2005

1. Amarnath Chatterjee, Ashutosh Kumar, Jeetender Chugh, Sudha Srivastava, Neel S Bhavesh and Ramakrishna V Hosur* NMR of unfolded proteins 

Chem. Sci. (Indian Academy of Sciences); 2005, 117(1), 3-21

2015

8. Michael D. Swanson1, Daniel M. Boudreaux1, Loïc Salmon1, Jeetender Chugh, Harry C. Winter, Jennifer L. Meagher, Sabine André, Paul V. Murphy, Stefan Oscarson, René Roy, Steven King, Mark H. Kaplan, Irwin J. Goldstein, E. Bart Tarbet, Brett L. Hurst, Donald F. Smee, Cynthia de la Fuente, Hans-Heinrich Hoffmann, Yi Xue, Charles M. Rice, Dominique Schols, J. Victor Garcia, Jeanne A. Stuckey, Hans-Joachim Gabius, Hashim M. Al-Hashimi*, and David M. Markovitz* Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity 

Cell; 2015, 163(3), 746-58 1Authors contributed equally

2014

7. Xiancheng Zeng, Jeetender Chugh, Anette Casiano, Hashim M Al-Hashimi*, Charlie Brooks III* Flipping of the ribosomal A-site adenines provides basis for tRNA selection 

Journal of Molecular Biology; 2014, 426(19), 3201-3213

2013

6. Hashim M Al-Hashimi (Presenting Author), Katja Petzold, Jeetender Chugh, Anthony M Mustoe, Elizabeth A Dethoff and Charlie Brooks III Predictive Understanding of RNA Dynamic Behavior: Bringing Order to Disorder 

The FASEB Journal; 2013, 27(96.1) (Conference Abstract)

2012

5. Elizabeth A Dethoff1, Katja Petzold1, Jeetender Chugh1, Anette Casiano, and Hashim M Al-Hashimi* Visualizing Transient Low Populated Structures of RNA 

Nature; 2012, 491(7426), 724-728 (Featured as News of the Week in C&EN; 2012, 90(42), 10) 1Authors contributed equally

4. Elizabeth A Dethoff1, Jeetender Chugh1, Anthony M Mustoe and Hashim M Al-Hashimi* Functional Complexity and Regulation through RNA Dynamics 

Nature; 2012, 482(7385), 322-330 (Featured as an Insight Article) 1Authors contributed equally

2011

3. Jeetender Chugh (Presenting Author), Anette Casiano-Negroni and Hashim M Al-Hashimi* NMR Dissection of the Detailed Mechanism for Antibiotic Binding to A-site RNA 

Biophysical Journal; 2011, 100(3), Supplemental 1, 603a (Conference Abstract)

2. Jameson R Bothe, Evgenia N Nikolova, Catherine D Eichhorn, Jeetender Chugh, Alexandar L. Hansen, and Hashim M. Al-Hashimi* Characterizing RNA Dynamics at Atomic Resolution using Solution-State NMR Spectroscopy 

Nature Methods; 2011, 8(11), 919-931

2010

1. Benjamin C Buer, Jeetender Chugh, Hashim M Al-Hashimi and E Neil G Marsh* Using fluorine NMR to probe the interaction of membrane-active peptides with the lipid bilayer 

Biochemistry; 2010, 49(27), 5760-5765