Jon

JON SHEZAF jonshezaf@utexas.edu

Jonathan was born in San Diego, California, but spent his formative years in Los Angeles. He graduated with his B.S in Chemistry from the University of San Francisco in 2019. While there, he studied the contributions of heavy-atom quantum mechanical tunneling to the dynamic processes of annulenes under the supervision of Dr. Claire Castro and Dr. William Karney. After graduation, he worked as a high school chemistry teacher at ICA Cristo Rey Academy in San Francisco. In the fall of 2020, he joined the Krische group and is interested in both total synthesis and methods development.

Jons's Publications

8. “Leveraging the Stereochemical Complexity of Octahedral Diastereomeric-at-Metal Catalysts to Unlock Regio- Diastereo and Enantioselectivity in Alcohol-Mediated C-C Couplings via Hydrogen Transfer,” Shezaf, J. Z.; Santana, C. G.; Ortiz, E.; Meyer, C. C.; Liu, P.; Sakata, K.; Huang. K.-W.; Krische, M. J. J. Am. Chem. Soc. 2024, 146, DOI: 10.1021/jacs.4c01857.

7. “Palladium(I)-Iodide Catalyzed Deoxygenative Heck Reaction of Vinyl Triflates: A Formate-Mediated Cross-Electrophile Reductive Coupling with cine-Substitution,” Chang, Y.-H.; Shen, W.; Shezaf, J. Z.; Ortiz, E.; Krische, M. J. J. Am. Chem. Soc. 2023, 145, DOI: 10.1021/jacs.3c09876.

6. “Chiral-at-Ruthenium-SEGPHOS Catalysts Display Diastereomer-Dependent Regioselectivity: Enantioselective Isoprene-Mediated Carbonyl tert-Prenylation via Halide Counterion Effects,” Shezaf, J. Z.; Santana, C. G.; Saludares, C.; Briceno, E. S.; Sakata, K.; Krische, M. J. J. Am. Chem. Soc. 2023, 145, 18676. (DOI: 10.1021/jacs.3c06734).

5. “Ruthenium-Catalyzed C-C Coupling of Terminal Alkynes with Primary Alcohols or Aldehydes: α,β-Acetylenic Ketones (Ynones) via Oxidative Alkynylation,” Ortiz, E.; Evarts, M. M.; Strong, Z. H.; Shezaf, J. Z. Angew. Chem. Int. Ed. 2023, 62, In Press (DOI: 10.1002/anie.202303345).

4. “Ruthenium-Catalyzed Dehydrogenation: Historical Perspective and Survey of Enantioselective for Conversion of Lower Alcohols to Higher Alcohols,” Ortiz, E.; Shen, W.; Shezaf, J. Z.; Krische, M. J. Chem. Sci. 2022, 13, DOI: 10.1039/d2sc05621f.

3. “Enantioselective Metal-Catalyzed Reductive Coupling of Alkynes with Carbonyl Compounds and Imines: Convergent Construction of Allylic Alcohols and Amines” Ortiz, E.; Shezaf, J. Z.; Chang, Y.-H.; Krische, M. J. ACS Catal. 2022, 12, 8164.

2. “Stereo- and Site-Selective Conversion of Primary Alcohols to Allylic Alcohols via Ruthenium-Catalyzed Hydrogen Auto-Transfer Mediated by 2-Butyne,” Ortiz, E.; Chang, Y.-H.; Shezaf, J. Z.; Shen, W.; Krische, M. J. J. Am. Chem. Soc. 2022, 144, 8861.

1. "Understanding Halide Counterion Effects in Enantioselective Ruthenium-Catalyzed Carbonyl (α-Aryl)allylation: Alkynes as Latent Allenes and TFE-Enhanced Turnover in The Conversion of Ethanol to Higher Alcohols via Hydrogen Auto-Transfer,” Ortiz, E.; Shezaf, J. Z.; Chang, Y.-H.; Théo P. Gonçalves, Kuo-Wei Huang, Krische, M. J. J. Am. Chem. Soc. 2021, 143, 16709.