Cate

CATHERINE GAZOLLA SANTANA cgsantana@utexas.edu

Cate was born in the state of São Paulo, Brazil, and received her B.S. in Chemical Engineering at the University of São Paulo in 2019. While there, she worked on a new method for selective mono-bromination of naphthalene anhydrides under the supervision of Dr. Eduardo Triboni and Dr. Joe Reczek. In the fall of 2020, she joined the Krische group and is interested in both total synthesis and method development.

Cate's Publications

6. “Formate-Mediated Reductive Cross-Coupling of Vinyl Halides with Aryl Iodides: cine-Substitution via Palladium(I)-Catalysis,” Santana, C. G.; Teoh, Y. S.; Evarts, M. M.; Shezaf, J. Z.; Krische, M. J. Org. Lett. 2024, 26, DOI: org/10.1021/acs.orglett.4c02642.

5. “Leveraging the Stereochemical Complexity of Octahedral Diastereomeric-at-Metal Catalysts to Unlock Regio- Diastereo and Enantioselectivity in Alcohol-Mediated C-C Couplings via Hydrogen Transfer,” Shezaf, J. Z.; Santana, C. G.; Ortiz, E.; Meyer, C. C.; Liu, P.; Sakata, K.; Huang. K.-W.; Krische, M. J. J. Am. Chem. Soc. 2024, 146, 7905. (DOI: 10.1021/jacs.4c01857.)

4. “Chiral-at-Ruthenium-SEGPHOS Catalysts Display Diastereomer-Dependent Regioselectivity: Enantioselective Isoprene-Mediated Carbonyl tert-Prenylation via Halide Counterion Effects,” Shezaf, J. Z.; Santana, C. G.; Saludares, C.; Briceno, E. S.; Sakata, K.; Krische, M. J. J. Am. Chem. Soc. 2023, 145, 18676. (DOI: 10.1021/jacs.3c06734.)

3. “Carbonyl Allylation and Crotylation: Historical Perspective, Relevance to Polyketide Synthesis, and Evolution of Enantioselective Ruthenium-Catalyzed Hydrogen Auto-Transfer Processes,” Ortiz, E.; Saludares, C.; Wu, J.; Cho, Y.; Santana, C. G.; Krische, M. J Synthesis. 2023, 55, 1487. (DOI: 10.1055/s-0042-1751420)

2. “Asymmetric Ruthenium-Catalyzed Carbonyl Allylations by Gaseous Allene via Hydrogen Auto-Transfer: 1º vs 2º Alcohol Dehydrogenation for Streamlined Polyketide Construction,” Saludares, C.; Ortiz, E.; Santana, C. G.; Spinello, B. J. ACS Catal. 2023, 13, 1662. (DOI: 10.1021/acscatal.2c05425.)

1. “From Hydrogenation to Transfer Hydrogenation to Hydrogen Auto-Transfer in Enantioselective Metal-Catalyzed Carbonyl Reductive Coupling: Past, Present and Future,” Santana, C. G.; Krische, M. J. ACS Catal. 2021, 11, 5572.