Documents

Publications

Peer-Reviewed Journal Articles

• Large-scale Pan Genomic Analysis of Mycobacterium tuberculosis Reveals Key Insights Into Molecular Evolutionary Rate of Specific Processes and Functions. Bundhoo E, Ghoorah AW, Jaufeerally-Fakim Y. Evolutionary Bioinformatics, 20 (2024)

• Prevalence, genomic characterization, and risk assessment of human pathogenic Vibrio species in seafood.  Neetoo et al. Journal of Food Protection, doi: 10.4315/JFP-22-064 (2022),  

• African Genomic Medicine Portal: A Web Portal for Biomedical Applications. Othman, H., Zass, L., et al.  Journal of Personalized Medicine, 12, 265 (2022).

• Population Structure of the South West Indian Ocean Islands: Implications for Precision Medicine. Ghoorah, AW, Chaplain, T, Rindra, R, Goorah, S, Chinien, G, Jaufeerally-Fakim, Y.  Frontiers in Genetics, 12, 2295 (2021).

• TAGOPSIN: collating taxa-specific gene and protein functional and structural information. Bundhoo, E, Ghoorah, AW, Jaufeerally-Fakim, Y. BMC Bioinformatics, 22, 1:517 (2021).

• High Depth African Genomes Inform Human Migration and Health. Choudhury, A., Aron, S., Botigué, L.R. et al. Nature 586, 741–748 (2020).

• Discovering novel driver mutations from pan-cancer analysis of mutational and gene expression profiles. Tegally et al. PLoS One, 15, 11:e0242780 (2020)

• Modeling and Minimising CAPRI Round 30 Symmetrical Protein Complexes from CASP-11 Structural Models. El Houasli, M.†, Maigret, M., Devignes, M.-D., Ghoorah, A. W., Grudinin, S. and Ritchie, D.W. (2016) PROTEINS: Structure, Function, and Bioinformatics 2016, 85(3),463–469.

• Prediction of homo- and hetero-protein complexes by protein docking and template-based modeling: a CASP-CAPRI experiment. Lensink, M.†, ... Ghoorah, A.W. ... and many others (2016). PROTEINS: Structure, Function, and Bioinformatics 2016, 84 (S1):323–348.

• Structure-Based Classification and Analysis of Protein Domain Family Binding Sites and Their Interactions. Ghoorah, A.W.†, Devignes, M-D., Alborzi, S.Z., Smaïl-Tabbone, M., Ritchie, D.W. (2015). Biology 2015; 4: 327-343.

• Kbdock 2013: A spatial classification of 3D protein domain family interactions. Ghoorah A.W.†, Devignes M-D., Smaïl-Tabbone M., and Ritchie D.W. (2014). Nucleic Acids Research 2014; 42(D1): 389-395.

• Protein docking using case-based reasoning. Ghoorah A.W.†, Devignes M-D., Smaïl-Tabbone M., and Ritchie D.W. (2013). PROTEINS: Structure, Function, and Bioinformatics 2013; 81(12): 2150-2158.

• Fast Protein Structure Alignment using Gaussian Overlap Scoring of Backbone Peptide Fragment Similarity. Ritchie D.W.†, Ghoorah A.W., Mavridis L., Venkatraman V. (2012). Bioinformatics 2012; 28 (24): 3274-81 (Supplementary Materials).

• Representing and comparing protein folds and fold families using 3D shape-density representations. Mavridis L.†, Ghoorah A.W., Venkatraman V., and Ritchie D.W. (2012). PROTEINS: Structure, Function, and Bioinformatics 2012; 80(2): 530-545.

• Spatial clustering of protein binding sites for template-based protein docking. Ghoorah A.W.†, Devignes M-D., Smaïl-Tabbone M., and Ritchie D.W. (2011). Bioinformatics 2011; 27(20): 2820-7. [PDF] (see Supplementary Materials for detailed homology docking results).

• jMOTU and Taxonerator: Turning DNA Barcode Sequences into Annotated Operational Taxonomic Units. Jones M.†, Ghoorah A.W.†, and Blaxter M. (2011). PLoS One. 2011; 6(4): e19259.

Book Chapters

• Genomic Data Sharing.  Kumuthini et al. (2023). In Genomic Data Sharing - Case Studies, Challenges, and opportunities for Precision Medicine (Eds. J. B. McCormick and J. Pathak).  Academic Press. Elsevier. 

• Data Standardization in the Omics Field. Kumuthini et al. (2023). In Genomic Data Sharing - Case Studies, Challenges, and opportunities for Precision Medicine (Eds. J. B. McCormick and J. Pathak).  Academic Press. Elsevier. 

• Classification and Exploration of 3D Protein Domain Interactions Using Kbdock. Ghoorah, A.W.†, Devignes, M-D., Smail-Tabbone, M., Ritchie, D.W. (2016). In Methods in Molecular Biology 1415 - Data Mining Techniques for the Life Sciences (Eds. O. Carugo and F. Eisenhaber), 2, 91-105.

Conference Proceedings

• Maudarbux M.M., Ghoorah A.W., Fowdur T.P. (2019) Sirius: A Resource for Analyzing Drug-Disease Relationships for Drug Repositioning. In: Fleming P., Lacquet B., Sanei S., Deb K., Jakobsson A. (eds) Smart and Sustainable Engineering for Next Generation Applications. ELECOM 2018. Lecture Notes in Electrical Engineering, vol 561. Springer, Cham.  https://doi.org/10.1007/978-3-030-18240-3_22.    

Presentations

• Husnoo-Moonien A, Ghoorah AW, Jaufeerally-Fakim Y (2023). Genetic diversity in immune receptor genes in African populations. 14TTh International Congress on Human Genetics (ICHG 2023), Cape Town. 

• Kbdock - a case-based reasoning approach to model 3D protein complexes, 5th CAPRI Evaluation Meeting, Utrecht, 2013. [PDF] (This talk was given by Dave Ritchie)

• Knowledge-based approaches for modelling the 3D structural interactome, PhD Defence, Ecole Doctorale IAEM, Université de Lorraine, LORIA, INRIA, Nancy, 2012. [PDF]

• Spatial Clustering of Protein Binding Sites for Template-Based Protein Docking, BeNeLux Bioinformatics Conference (BBC 2011), Luxembourg, 2011.

• Extracting and visualising protein-protein interfaces for knowledge-based docking, Journées Scientifiques de la Fédération Charles Hermite, Nancy, 2010.

Posters (international conferences only)

• TAGOPSIN: a tool for retrieving taxa-specific protein structural and functional information. ISCB/ISMB 2020 (doi: 10.7490/f1000research.1118251.1)

• Network Analysis of Protein-Protein Interactions relevant in Atherosclerosis and Rheumatoid Arthritis. ISCB/ISMB 2020 (doi: 10.7490/f1000research.1118261.1)

• Representing and comparing protein folds and families using 3D shape-density representations. ISMB-3DSIG, Vienna, 2011. [PDF]

• Extracting and visualizing protein-protein complexes for knowledge-based docking. LIX Bioinformatics Colloquium 2010, Paris, 2010. [PDF]

• Extracting and visualizing protein-protein complexes for knowledge-based docking. 9th ECCB, Ghent, 2010. [PDF]

• Using Human Expertise in Protein-Protein Docking: From Biological Knowledge to Interactive Simulations. 4th CAPRI Evaluation Meeting, Barcelona, 2009. [PDF]

• Developing a Knowledge-Based Approach to Protein-Protein Docking. 4th CAPRI Evaluation Meeting, Barcelona, 2009. [PDF]

Other

• Knowledge-based approaches for modelling the 3D structural interactome, PhD Thesis, University of Lorraine, 2012. [PDF]

• MOTU_define: A tool for DNA barcode analyses, MSc Thesis, University of Edinburgh, 2008.

• Aligning protein 3D structures, Undergraduate Project Report, University of Aberdeen, 2007.

• ORCID https://orcid.org/0000-0001-8273-6000