PQGen teaching program Web site
The aim of this software is to be a complementary resource for an introductory course on Populations and Quantitative Genetics in diploid organisms, with special orientation to the animal breeding.
It calculates the parameters of some essential topics and visualizes some situa- tions graphically by means of deterministic (infinite size populations) or stochastic (finite populations) simulations.
This version has been developed in Liberty Basic on Windows operating system. Needs to be run as administrator. This software also runs on Mac and Linux environ ments through interfaces such as WineBottler.
This program only uses the modules placed in the installation directory, with the exception of CALC and OSK of Windows.
This software is shareware. The suggestions that allow to improve this program and to correct the mistakes will be appreciated. Moreover, efforts to expand this program to other languages will also be welcomed. At present the Help of program is in English, French, Portuguese, Spanish and Turkish.
New!: Module 21 of Population genetics.
Modules 16 and 17 of Quantitative genetics.
To contact: altarrib@unizar.es
Este programa pretende ser el complemento de un curso introductorio a la Genética de Poblaciones y a la Genética Cuantitativa en organismos diploides, con especial orientación a la mejora genética animal.
Calcula los parámetros de algunos tópicos esenciales y visualiza gráficamente algunas situaciones mediante simulación determinística (en poblaciones infinitas) o estocástica (en poblaciones concretas).
Esta versión ha sido desarrollada en Liberty Basic en un entorno Windows. Necesita ejecutarse como administrador. También funciona en entornos Mac y Linux mediante interfaces como WineBottler.
Este programa solo utiliza los módulos colocados en el directorio de instalación, salvo CALC y OSK de Windows.
En Practicando con PQGen existe una guía didáctica de cada módulo con ejemplos comentados.
Software de libre distribución. Se agradecerán las sugerencias que permitan mejorar este programa, corregir errores y realizar traducciones de la Ayuda en otros idiomas. Actualmente está en Español, Francés, Inglés, Portugués y Turco.
¡New!: Módulo 21 de Genética de poblaciones.
Módulos 16 y 17 de Genética Cuantitativa
Contactar: altarrib@unizar.es
Programmed modules
Population genetics
1. Hardy-Weinberg equilibrium
2. Gene frequencies and HW equilibrium for autosomal loci
3. Evolution of sex linked loci
4. Map distance and recombination frequencies
5. Gametic frequencies evolution and linkage disequilibrium
6. Linkage disequilibrium
7. Predictive ability of a marker
8. Haplotype prediction in a gen with dominance
9. Assortative mating
10. Migration
11. Mutation
12. Selection
13. Hitchhiking effect on linked locus from selection
14. Mutation - Selection balance
15. Selection for fitness defined by two loci
16. Gene sampling - Genetic drift
17. Joint effect of selection and genetic drift
18. Individual inbreeding
19. Relationship matrices
20. Founder effects
21. Variability of realized relationship and inbreeding coefficients
22. Effective size and population inbreeding
23. Empirical molecular relationship from coefficient of correlation
24. Molecular relationship matrices in relation to genealogical relationship
Quantitative genetics
1. Genetic structure of a quantitative trait
2. Selection for components of the genotipic values
3. The mendelian segregation in a quantitative locus
4. Sampling of a quantitative trait
5. Distribution of the additive genetic value for the descendents
6. Empiric relation of genetic components beetween relatives
7. Heritability estimation - Analysis of variance
8. Heritability estimation - Regression analysis
9. Selection effects on the genetic structure of a population
10. Inbreeding effects on the genetic structure of a population
11. Crossbreeding effects on the genetic structure of populations
12. Reciprocal Recurrent selection (RRS)
13. Selection index and breeding values distributions
14. Properties of the selection index as a selection criterion
15. Efficiency of selection indexes depending of the information source
16. BLP with multiple relationships, inbreeding and accuracy
17. BLUP animal model - Cost estimation of the mean and accuracy of â
18. Best Linear Unbiased Prediction - Sire model
19. Best Linear Unbiased Prediction - Animal model
20. Correlated response
21. Genetic correlation between traits and linkage disequilibrium
22. Categorical traits. Threshold model
23. Comparison between selection criteria
24. Marker assisted selection efficiency
25. Background of detection a Qtl from a Marker locus
26. Relation between objective and criterion of selection