Publications

Medline links

  1. McCartney CR, Campbell RE, Marshall JC, Moenter SM 2022 The role of gonadotropin-releasing hormone neurons in polycystic ovary syndrome. J Neuroendocrinology e13093, https://doi.org/10.1111/jne.13093 (pubmed)

  2. Han X, Burger LL, Garcia Galiano D, Moenter SM, Myers MG, Olson DP, Elias CF 2021 Protocol to extract actively translated mRNAs from mouse hypothalamus by translating ribosome affinity purification. STAR Protocols 2, 100589, June 18, 2021. PMC8196219 (pubmed)

  3. DeFazio RA, Moenter SM 2021 Lack of sex differences in gonadotropin-releasing hormone (GnRH) neuron potassium currents and excitability. 2021 Jul 7;8(4):ENEURO.0126-21.2021 BIORXIV/2021/03/24/436851, PMC8266219 (pubmed)

  4. Vanacker CMH, DeFazio RA, Sykes CM, Moenter SM 2021 A role for glial fibrillary acidic protein (GFAP)-expressing cells in the regulation of gonadotropin-releasing hormone (GnRH) but not arcuate kisspeptin neuron output. Jul 22;10:e68205. doi: 10.7554/eLife.68205. BIORXIV/2021/434805, PMC8337074 (pubmed)

  5. Starrett JR, DeFazio RA, Moenter SM 2021 Reciprocal changes in voltage-gated potassium and subthreshold inward currents help maintain firing dynamics of AVPV kisspeptin neurons during the estrous cycle. eNeuro 0324-21.2021, BIORXIV/2021/452390, PMC8422850 (pubmed)

  6. Gibson AG, Jaime J, Burger LL, Moenter SM 2021 Prenatal androgen treatment does not alter the firing activity of hypothalamic arcuate kisspeptin neurons in female mice. ENEURO.0306-21.2021.doi: 10.1523/ENEURO.0306-21.2021BIORXIV/2021/452845 PMC8482853 (pubmed)

  7. Moenter SM, Evans NP 2021 Gonadotropin-releasing hormone (GnRH) measurements in pituitary portal blood: a history. J Neuroendocrinology e13065, https://doi.org/10.1111/jne.13065 (pubmed)

  8. Phumsatitpong C, Wagenmaker ER, Moenter SM 2021 Neuroendocrine interactions of the stress and reproductive axes. Frontiers in Neuroendocrinology 63:100928 (pubmed)

  9. Constantin S, Moenter SM, Piet R 2021 The electrophysiologic properties of gonadotropin-releasing hormone neurons. J Neuroendocrinology e13073, https://doi.org/10.1111/jne.13073 (pubmed)

  10. Dulka EA, Burger LL, Moenter SM 2020 Ovarian androgens maintain high GnRH neuron firing rate in adult prenatally androgenized female mice. Endocrinology, 161: pii: bqz038. doi: 10.1210/endocr/bqz038. PMC7397485 (pubmed)

  11. Dulka EA, DeFazio RA, Moenter SM 2020 Chemogenetic suppression of GnRH neurons during pubertal development can alter adult GnRH neuron firing rate and reproductive parameters in female mice. eNeuro eNeuro.0223-20.2020, PMC7363480 (pubmed)

  12. Penix J, DeFazio RA, Dulka EA, Schnell S, Moenter SM 2020 Firing patterns of gonadotropin-releasing hormone (GnRH) neurons are sculpted by their biologic state. Royal Society Open Science, 7:201040 PMC7481724 (pubmed)

  13. Phumsatitpong C, De Guzman R, Zuloaga DG, Moenter SM 2020 A CRH receptor type 1 agonist increases GABA transmission to GnRH neurons in a circulating-estradiol-dependent manner. Endocrinology 161: :bqaa140 PMC5761586 (pubmed)

  14. Abbara A, Eng PC, Phylactou M, Clarke SA, Richardson R, Sykes CM, Phumsatitpong C, Mills E, Modi M, Izzi-Engbeaya C, Papadopoulou D, Purugganan K, Jayasena CN, Webber L, Salim R, Owen B, Bech P, Comninos AN, McArdle CA, Voliotis M, Tsaneva-Atanasova K, Moenter SM, Hanyaloglu A, Dhillo WS. 2020 Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders. J Clin Invest 130(12):6739-6753, PMC7685751 (pubmed)

  15. Burger LL, Wagenmaker ER, Phumsatitpong C, Olson DP, Moenter SM 2020 Translating ribosome affinity purification and RNA sequencing identifies GnRH neuron-specific genes regulated by development and prenatal androgen exposure in female mice. Endocrinology. 10.1210/endocr/bqaa166 PMC7583650 (pubmed)

  16. Moenter SM, Silveira MA, Wang L, Adams C 2019 Central aspects of systemic estradiol negative and positive feedback on the reproductive neuroendocrine system. J Neuroendocrinol, e12724, PMC6829026, NIHMS1026645 (pubmed)

  17. Wang L, Moenter SM 2019 Differential roles of hypothalamic AVPV and arcuate kisspeptin neurons in estradiol feedback regulation of female reproduction, Neuroendocrinology, doi: 10.1159/000503006, PMC7047625, NIHMS1049711 (pubmed)

  18. DeFazio RA, Navarro MA, Adams CE, Milescu LS, Moenter SM 2019 Estradiol enhances the depolarizing response to GABA and AMPA synaptic conductances in arcuate kisspeptin neurons by diminishing voltage-gated potassium currents. J Neurosci, 39:9532-9545, PMC6880461. (pubmed)

  19. SM, Silveira MA, Wang L, Adams C. Central aspects of systemic oestradiol negative- and positive-feedback on the reproductive neuroendocrine system. J Neuroendocrinol. 2019 May 4:e12724. (Pubmed)

  20. Wang L, Vanacker C, Burger LL, Barnes T, Shah YM, Myers MG, Moenter SM. Genetic dissection of the different roles of hypothalamic kisspeptin neurons in regulating female reproduction. Elife. 2019 Apr 4;8. pii: e43999. (Pubmed)

  21. Adams C, DeFazio RA, Christian CA, Milescu LS, Schnell S, Moenter SM. Changes in Both Neuron Intrinsic Properties and Neurotransmission Are Needed to Drive the Increase in GnRH Neuron Firing Rate during Estradiol-Positive Feedback. J Neurosci. 2019 Mar 13;39(11):2091-2101. (Pubmed)

  22. Adams C, Chen X, Moenter SM. Changes in GABAergic Transmission to and Intrinsic Excitability of Gonadotropin-Releasing Hormone (GnRH) Neurons during the Estrous Cycle in Mice. eNeuro. 2018 Nov 8;5(5). (Pubmed)

  23. Lehman MN, Coolen LM, Steiner RA, Neal-Perry G, Wang L, Moenter SM, Moore AM, Goodman RL, Hwa-Yeo S, Padilla SL, Kauffman AS, Garcia J, Kelly MJ, Clarkson J, Radovick S, Babwah AV, Leon S, Tena-Sempere M, Comninos A, Seminara S, Dhillo WS, Levine J, Terasawa E, Negron A, Herbison AE. The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond":Unresolved questions, challenges and future directions for the field. J Neuroendocrinol. 2018 Apr 14:e12600. (Pubmed)

  24. Burger LL, Vanacker C, Phumsatitpong C, Wagenmaker ER, Wang L, Olson DP, Moenter SM. Identification of Genes Enriched in GnRH Neurons by Translating Ribosome Affinity Purification and RNAseq in Mice. Endocrinology. 2018 Apr 1;159(4):1922-1940. (Pubmed)

  25. Berg T, Silveira MA, Moenter SM. Prepubertal Development of GABAergic Transmission to Gonadotropin-Releasing Hormone (GnRH) Neurons and Postsynaptic Response Are Altered by Prenatal Androgenization. J Neurosci. 2018 Feb 28;38(9):2283-2293. (Pubmed)

  26. Adams C, Stroberg W, DeFazio RA, Schnell S, Moenter SM. Gonadotropin-Releasing Hormone (GnRH) Neuron Excitability Is Regulated by Estradiol Feedback and Kisspeptin. J Neurosci. 2018 Jan 31;38(5):1249-1263. (Pubmed)

  27. Moenter SM. GnRH Neurons on LSD: A Year of Rejecting Hypotheses That May Have Made Karl Popper Proud. Endocrinology. 2018 Jan 1;159(1):199-205. (Pubmed)

  28. Wang L, Burger LL, Greenwald-Yarnell ML, Myers MG Jr, Moenter SM. Glutamatergic Transmission to Hypothalamic Kisspeptin Neurons Is Differentially Regulated by Estradiol through Estrogen Receptor α in Adult Female Mice. J Neurosci. 2018 Jan 31;38(5):1061-1072. (Pubmed)

  29. Phumsatitpong C, Moenter SM. Estradiol-Dependent Stimulation and Suppression of Gonadotropin-Releasing Hormone Neuron Firing Activity by Corticotropin-Releasing Hormone in Female Mice. Endocrinology. 2018 Jan 1;159(1):414-425. (Pubmed)

  30. Dulka EA, Moenter SM. Prepubertal Development of Gonadotropin-Releasing Hormone Neuron Activity Is Altered by Sex, Age, and Prenatal Androgen Exposure. Endocrinology. 2017 Nov 1;158(11):3943-3953. (Pubmed)

  31. Vanacker C, Moya MR, DeFazio RA, Johnson ML, Moenter SM. Long-Term Recordings of Arcuate Nucleus Kisspeptin Neurons Reveal Patterned Activity That Is Modulated by Gonadal Steroids in Male Mice. Endocrinology. 2017 Oct 1;158(10):3553-3564. (Pubmed)

  32. Wagenmaker ER, Moenter SM. Exposure to Acute Psychosocial Stress Disrupts the Luteinizing Hormone Surge Independent of Estrous Cycle Alterations in Female Mice. Endocrinology. 2017 Aug 1;158(8):2593-2602. (Pubmed)

  33. Silveira M, Burger LL, DeFazio RA, Wagenmaker ER, Moenter SM. GnRH neuron activity and pituitary response in estradiol-induced vs proestrous luteinizing hormone surges in female mice. Endocrinology. 2017 Feb 1;158(2):356-366.

  34. Wang L, DeFazio RA, Moenter SM. Excitability and Burst Generation of AVPV Kisspeptin Neurons Are Regulated by the Estrous Cycle Via Multiple Conductances Modulated by Estradiol Action. eNeuro. 2016 Jun 7;3(3). pii: ENEURO.0094-16.2016. doi: 10.1523/ENEURO.0094-16.2016. PubMed PMID: 27280155; PubMed Central PMCID: PMC4895127.

  35. Moran S, Moenter SM, Khadra A. A unified model for two modes of bursting in GnRH neurons. J Comput Neurosci. 2016 Jun;40(3):297-315. doi: 10.1007/s10827-016-0598-4. PubMed PMID: 26975615; PubMed Central PMCID: PMC4860362.

  36. Greenwald-Yarnell ML, Marsh C, Allison MB, Patterson CM, Kasper C, MacKenzie A, Cravo R, Elias CF, Moenter SM, Myers MG Jr. ERα in Tac2 Neurons Regulates Puberty Onset in Female Mice. Endocrinology. 2016 Apr;157(4):1555-65. doi: 10.1210/en.2015-1928. PubMed PMID: 26862996; PubMed Central PMCID: PMC4816740.

  37. Ruka KA, Burger LL, Moenter SM. Both Estrogen and Androgen Modify the Response to Activation of Neurokinin-3 and κ-Opioid Receptors in Arcuate Kisspeptin Neurons From Male Mice. Endocrinology. 2016 Feb;157(2):752-63. doi: 10.1210/en.2015-1688. PubMed PMID: 26562263; PubMed Central PMCID: PMC4733114.

  38. Homa LD, Burger LL, Cuttitta AJ, Michele DE, Moenter SM. Voluntary Exercise Improves Estrous Cyclicity in Prenatally Androgenized Female Mice Despite Programming Decreased Voluntary Exercise: Implications for Polycystic Ovary Syndrome (PCOS). Endocrinology. 2015 Dec;156(12):4618-28. doi: 10.1210/en.2015-1593. PubMed PMID: 26360506; PubMed Central PMCID: PMC4655213.

  39. Moenter SM. Leap of Faith: Does Serum Luteinizing Hormone Always Accurately Reflect Central Reproductive Neuroendocrine Activity? Neuroendocrinology. 2015;102(4):256-266. PubMed PMID: 26278916; PubMed Central PMCID: PMC4675678.

  40. DeFazio RA, Elias CF, Moenter SM. GABAergic transmission to kisspeptin neurons is differentially regulated by time of day and estradiol in female mice. J Neurosci. 2014 Dec 3;34(49):16296-308. doi: 10.1523/JNEUROSCI.3057-14.2014. PubMed PMID: 25471569; PubMed Central PMCID: PMC4252544.

  41. Glanowska KM, Burger LL, Moenter SM. Development of gonadotropin-releasing hormone secretion and pituitary response. J Neurosci. 2014 Nov 5;34(45):15060-9. doi: 10.1523/JNEUROSCI.2200-14.2014. PubMed PMID: 25378170; PubMed Central PMCID: PMC4220034.

  42. Glanowska KM, Moenter SM. Differential regulation of GnRH secretion in the preoptic area (POA) and the median eminence (ME) in male mice. Endocrinology. 2015 Jan;156(1):231-41. doi: 10.1210/en.2014-1458. PubMed PMID: 25314270; PubMed Central PMCID: PMC4272400.

  43. Roland AV, Moenter SM. Reproductive neuroendocrine dysfunction in polycystic ovary syndrome: insight from animal models. Front Neuroendocrinol. 2014 Oct;35(4):494-511. doi: 10.1016/j.yfrne.2014.04.002. Review. PubMed PMID: 24747343; PubMed Central PMCID: PMC4175187.

  44. Gaskins GT, Glanowska KM, Moenter SM. Activation of neurokinin 3 receptors stimulates GnRH release in a location-dependent but kisspeptin-independent manner in adult mice. Endocrinology. 2013 Nov;154(11):3984-9. doi: 10.1210/en.2013-1479. PubMed PMID: 23928373; PubMed Central PMCID: PMC3800761.

  45. Ruka KA, Burger LL, Moenter SM. Regulation of arcuate neurons coexpressing kisspeptin, neurokinin B, and dynorphin by modulators of neurokinin 3 and κ-opioid receptors in adult male mice. Endocrinology. 2013 Aug;154(8):2761-71. doi: 10.1210/en.2013-1268. PubMed PMID: 23744642; PubMed Central PMCID: PMC3713217.

  46. Glanowska KM, Venton BJ, Moenter SM. Fast scan cyclic voltammetry as a novel method for detection of real-time gonadotropin-releasing hormone release in mouse brain slices. J Neurosci. 2012 Oct 17;32(42):14664-9. doi: 10.1523/JNEUROSCI.1303-12.2012. PubMed PMID: 23077052; PubMed Central PMCID: PMC3492948.

  47. Gaskins GT, Moenter SM. Orexin a suppresses gonadotropin-releasing hormone (GnRH) neuron activity in the mouse. Endocrinology. 2012 Aug;153(8):3850-60. doi: 10.1210/en.2012-1300. PubMed PMID: 22673226; PubMed Central PMCID: PMC3404355.

  48. Chu Z, Tomaiuolo M, Bertram R, Moenter SM. Two types of burst firing in gonadotrophin-releasing hormone neurones. J Neuroendocrinol. 2012 Jul;24(7):1065-77. doi: 10.1111/j.1365-2826.2012.02313.x. PubMed PMID: 22435872; PubMed Central PMCID: PMC3380170.

  49. Moenter SM. Scene of the crime: where is GnRH released, and what might this tell us? Endocrinology. 2011 Nov;152(11):4014-5. doi: 10.1210/en.2011-1721. PubMed PMID: 22021199; PubMed Central PMCID: PMC3858666.

  50. Glanowska KM, Moenter SM. Endocannabinoids and prostaglandins both contribute to GnRH neuron-GABAergic afferent local feedback circuits. J Neurophysiol. 2011 Dec;106(6):3073-81. doi: 10.1152/jn.00046.2011. PubMed PMID: 21917995; PubMed Central PMCID: PMC3234080.

  51. Roland AV, Moenter SM. Regulation of gonadotropin-releasing hormone neurons by glucose. Trends Endocrinol Metab. 2011 Nov;22(11):443-9. doi: 10.1016/j.tem.2011.07.001. Review. PubMed PMID: 21855365; PubMed Central PMCID: PMC3205187.

  52. Pielecka-Fortuna J, DeFazio RA, Moenter SM. Voltage-gated potassium currents are targets of diurnal changes in estradiol feedback regulation and kisspeptin action on gonadotropin-releasing hormone neurons in mice. Biol Reprod. 2011 Nov;85(5):987-95. doi: 10.1095/biolreprod.111.093492. PubMed PMID: 21778142; PubMed Central PMCID: PMC3197916.

  53. Moenter SM. No holy grail for puberty. Nat Neurosci. 2011 Jun;14(6):670-2. doi: 10.1038/nn.2851. PubMed PMID: 21613992.

  54. Herbison AE, Moenter SM. Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones: towards an emerging consensus. J Neuroendocrinol. 2011 Jul;23(7):557-69. doi: 10.1111/j.1365-2826.2011.02145.x. Review. PubMed PMID: 21518033; PubMed Central PMCID: PMC3518440.

  55. Moenter SM, Chu Z. Rapid nongenomic effects of oestradiol on gonadotrophin-releasing hormone neurones. J Neuroendocrinol. 2012 Jan;24(1):117-21. doi: 10.1111/j.1365-2826.2011.02135.x. Review. PubMed PMID: 21496126; PubMed Central PMCID: PMC3983560.

  56. Roland AV, Moenter SM. Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase. Mol Endocrinol. 2011 May;25(5):847-58. doi: 10.1210/me.2010-0508. PubMed PMID: 21393446; PubMed Central PMCID: PMC3082325.

  57. Roland AV, Moenter SM. Prenatal androgenization of female mice programs an increase in firing activity of gonadotropin-releasing hormone (GnRH) neurons that is reversed by metformin treatment in adulthood. Endocrinology. 2011 Feb;152(2):618-28. doi: 10.1210/en.2010-0823. PubMed PMID: 21159854; PubMed Central PMCID: PMC3037157.

  58. Chu Z, Takagi H, Moenter SM. Hyperpolarization-activated currents in gonadotropin-releasing hormone (GnRH) neurons contribute to intrinsic excitability and are regulated by gonadal steroid feedback. J Neurosci. 2010 Oct 6;30(40):13373-83. doi: 10.1523/JNEUROSCI.1687-10.2010. PubMed PMID: 20926664; PubMed Central PMCID: PMC2968704.

  59. Farkas I, Kalló I, Deli L, Vida B, Hrabovszky E, Fekete C, Moenter SM, Watanabe M, Liposits Z. Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons. Endocrinology. 2010 Dec;151(12):5818-29. doi: 10.1210/en.2010-0638. PubMed PMID: 20926585; PubMed Central PMCID: PMC3858799.

  60. Moenter SM. Identified GnRH neuron electrophysiology: a decade of study. Brain Res. 2010 Dec 10;1364:10-24. doi: 10.1016/j.brainres.2010.09.066. Review. PubMed PMID: 20920482; PubMed Central PMCID: PMC2992586.

  61. Sun J, Moenter SM. Progesterone treatment inhibits and dihydrotestosterone (DHT) treatment potentiates voltage-gated calcium currents in gonadotropin-releasing hormone (GnRH) neurons. Endocrinology. 2010 Nov;151(11):5349-58. doi: 10.1210/en.2010-0385. PubMed PMID: 20739401; PubMed Central PMCID: PMC2954728.

  62. Roland AV, Nunemaker CS, Keller SR, Moenter SM. Prenatal androgen exposure programs metabolic dysfunction in female mice. J Endocrinol. 2010 Nov;207(2):213-23. doi: 10.1677/JOE-10-0217. PubMed PMID: 20713501; PubMed Central PMCID: PMC3612271.

  63. Sun J, Chu Z, Moenter SM. Diurnal in vivo and rapid in vitro effects of estradiol on voltage-gated calcium channels in gonadotropin-releasing hormone neurons. J Neurosci. 2010 Mar 17;30(11):3912-23. doi: 10.1523/JNEUROSCI.6256-09.2010. PubMed PMID: 20237262; PubMed Central PMCID: PMC2855130.

  64. Christian CA, Moenter SM. The neurobiology of preovulatory and estradiol-induced gonadotropin-releasing hormone surges. Endocr Rev. 2010 Aug;31(4):544-77. doi: 10.1210/er.2009-0023. Review. PubMed PMID: 20237240; PubMed Central PMCID: PMC3365847.

  65. Pielecka-Fortuna J, Moenter SM. Kisspeptin increases gamma-aminobutyric acidergic and glutamatergic transmission directly to gonadotropin-releasing hormone neurons in an estradiol-dependent manner. Endocrinology. 2010 Jan;151(1):291-300. doi: 10.1210/en.2009-0692. PubMed PMID: 19880809; PubMed Central PMCID: PMC2803153.

  66. Chen P, Moenter SM. GABAergic transmission to gonadotropin-releasing hormone (GnRH) neurons is regulated by GnRH in a concentration-dependent manner engaging multiple signaling pathways. J Neurosci. 2009 Aug 5;29(31):9809-18. doi: 10.1523/JNEUROSCI.2509-09.2009. PubMed PMID: 19657033; PubMed Central PMCID: PMC2747084.

  67. Brill DS, Moenter SM. Androgen receptor antagonism and an insulin sensitizer block the advancement of vaginal opening by high-fat diet in mice. Biol Reprod. 2009 Dec;81(6):1093-8. doi: 10.1095/biolreprod.109.079301. PubMed PMID: 19605781; PubMed Central PMCID: PMC2802232.

  68. Chu Z, Andrade J, Shupnik MA, Moenter SM. Differential regulation of gonadotropin-releasing hormone neuron activity and membrane properties by acutely applied estradiol: dependence on dose and estrogen receptor subtype. J Neurosci. 2009 Apr 29;29(17):5616-27. doi: 10.1523/JNEUROSCI.0352-09.2009. PubMed PMID: 19403828; PubMed Central PMCID: PMC2744362.

  69. Roseweir AK, Kauffman AS, Smith JT, Guerriero KA, Morgan K, Pielecka-Fortuna J, Pineda R, Gottsch ML, Tena-Sempere M, Moenter SM, Terasawa E, Clarke IJ, Steiner RA, Millar RP. Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation. J Neurosci. 2009 Mar 25;29(12):3920-9. doi: 10.1523/JNEUROSCI.5740-08.2009. PubMed PMID: 19321788; PubMed Central PMCID: PMC3035813.

  70. Moenter SM, Chu Z, Christian CA. Neurobiological mechanisms underlying oestradiol negative and positive feedback regulation of gonadotrophin-releasing hormone neurones. J Neuroendocrinol. 2009 Mar;21(4):327-33. doi: 10.1111/j.1365-2826.2009.01826.x. Review. PubMed PMID: 19207821; PubMed Central PMCID: PMC2738426.

  71. Christian CA, Pielecka-Fortuna J, Moenter SM. Estradiol suppresses glutamatergic transmission to gonadotropin-releasing hormone neurons in a model of negative feedback in mice. Biol Reprod. 2009 Jun;80(6):1128-35. doi: 10.1095/biolreprod.108.075077. PubMed PMID: 19176881; PubMed Central PMCID: PMC2804800.

  72. Christian CA, Glidewell-Kenney C, Jameson JL, Moenter SM. Classical estrogen receptor alpha signaling mediates negative and positive feedback on gonadotropin-releasing hormone neuron firing. Endocrinology. 2008 Nov;149(11):5328-34. doi: 10.1210/en.2008-0520. PubMed PMID: 18635656; PubMed Central PMCID: PMC2584581.

  73. Christian CA, Moenter SM. Critical roles for fast synaptic transmission in mediating estradiol negative and positive feedback in the neural control of ovulation. Endocrinology. 2008 Nov;149(11):5500-8. doi: 10.1210/en.2008-0453. PubMed PMID: 18617615; PubMed Central PMCID: PMC2584596.

  74. Gill JC, Wadas B, Chen P, Portillo W, Reyna A, Jorgensen E, Mani S, Schwarting GA, Moenter SM, Tobet S, Kaiser UB. The gonadotropin-releasing hormone (GnRH) neuronal population is normal in size and distribution in GnRH-deficient and GnRH receptor-mutant hypogonadal mice. Endocrinology. 2008 Sep;149(9):4596-604. doi: 10.1210/en.2008-0403. PubMed PMID: 18499748; PubMed Central PMCID: PMC2553368.

  75. Christian CA, Moenter SM. Vasoactive intestinal polypeptide can excite gonadotropin-releasing hormone neurons in a manner dependent on estradiol and gated by time of day. Endocrinology. 2008 Jun;149(6):3130-6. doi: 10.1210/en.2007-1098. PubMed PMID: 18326000; PubMed Central PMCID: PMC2408801.

  76. Pielecka-Fortuna J, Chu Z, Moenter SM. Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Endocrinology. 2008 Apr;149(4):1979-86. PubMed PMID: 18162521; PubMed Central PMCID: PMC2276721.

  77. Christian CA, Moenter SM. Estradiol induces diurnal shifts in GABA transmission to gonadotropin-releasing hormone neurons to provide a neural signal for ovulation. J Neurosci. 2007 Feb 21;27(8):1913-21. PubMed PMID: 17314287.

  78. Chu Z, Moenter SM. Physiologic regulation of a tetrodotoxin-sensitive sodium influx that mediates a slow afterdepolarization potential in gonadotropin-releasing hormone neurons: possible implications for the central regulation of fertility. J Neurosci. 2006 Nov 15;26(46):11961-73. PubMed PMID: 17108170.

  79. Pielecka J, Moenter SM. Effect of steroid milieu on gonadotropin-releasing hormone-1 neuron firing pattern and luteinizing hormone levels in male mice. Biol Reprod. 2006 May;74(5):931-7. PubMed PMID: 16452459.

  80. Pielecka J, Quaynor SD, Moenter SM. Androgens increase gonadotropin-releasing hormone neuron firing activity in females and interfere with progesterone negative feedback. Endocrinology. 2006 Mar;147(3):1474-9. PubMed PMID: 16339200.

  81. Christian CA, Mobley JL, Moenter SM. Diurnal and estradiol-dependent changes in gonadotropin-releasing hormone neuron firing activity. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15682-7. PubMed PMID: 16230634; PubMed Central PMCID: PMC1257388.

  82. Moenter SM, DeFazio RA. Endogenous gamma-aminobutyric acid can excite gonadotropin-releasing hormone neurons. Endocrinology. 2005 Dec;146(12):5374-9. PubMed PMID: 16123153.

  83. Chu Z, Moenter SM. Endogenous activation of metabotropic glutamate receptors modulates GABAergic transmission to gonadotropin-releasing hormone neurons and alters their firing rate: a possible local feedback circuit. J Neurosci. 2005 Jun 15;25(24):5740-9. PubMed PMID: 15958740; PubMed Central PMCID: PMC1201448.

  84. Bless EP, Walker HJ, Yu KW, Knoll JG, Moenter SM, Schwarting GA, Tobet SA. Live view of gonadotropin-releasing hormone containing neuron migration. Endocrinology. 2005 Jan;146(1):463-8. PubMed PMID: 15486219.

  85. Tsai PS, Moenter SM, Postigo HR, El Majdoubi M, Pak TR, Gill JC, Paruthiyil S, Werner S, Weiner RI. Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population. Mol Endocrinol. 2005 Jan;19(1):225-36. PubMed PMID: 15459253.

  86. Sullivan SD, Moenter SM. GABAergic integration of progesterone and androgen feedback to gonadotropin-releasing hormone neurons. Biol Reprod. 2005 Jan;72(1):33-41. PubMed PMID: 15342358.

  87. Gill JC, Moenter SM, Tsai PS. Developmental regulation of gonadotropin-releasing hormone neurons by fibroblast growth factor signaling. Endocrinology. 2004 Aug;145(8):3830-9. PubMed PMID: 15117872.

  88. Sullivan SD, Moenter SM. Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder. Proc Natl Acad Sci U S A. 2004 May 4;101(18):7129-34. PubMed PMID: 15096602; PubMed Central PMCID: PMC406477.

  89. Moenter SM, Defazio RA, Straume M, Nunemaker CS. Steroid regulation of GnRH neurons. Ann N Y Acad Sci. 2003 Dec;1007:143-52. Review. PubMed PMID: 14993048.

  90. Sullivan SD, Moenter SM. Gamma-aminobutyric acid neurons integrate and rapidly transmit permissive and inhibitory metabolic cues to gonadotropin-releasing hormone neurons. Endocrinology. 2004 Mar;145(3):1194-202. PubMed PMID: 14645118.

  91. Tsai PS, Moenter SM, Cavolina JM. Development of a novel enzyme immunoassay for the measurement of in vitro GnRH release from rat and bullfrog hypothalamic explants. Comp Biochem Physiol A Mol Integr Physiol. 2003 Nov;136(3):693-700. PubMed PMID: 14613797.

  92. Xu C, Xu XZ, Nunemaker CS, Moenter SM. Dose-dependent switch in response of gonadotropin-releasing hormone (GnRH) neurons to GnRH mediated through the type I GnRH receptor. Endocrinology. 2004 Feb;145(2):728-35. PubMed PMID: 14576189.

  93. Sullivan SD, DeFazio RA, Moenter SM. Metabolic regulation of fertility through presynaptic and postsynaptic signaling to gonadotropin-releasing hormone neurons. J Neurosci. 2003 Sep 17;23(24):8578-85. PubMed PMID: 13679427.

  94. Turi GF, Liposits Z, Moenter SM, Fekete C, Hrabovszky E. Origin of neuropeptide Y-containing afferents to gonadotropin-releasing hormone neurons in male mice. Endocrinology. 2003 Nov;144(11):4967-74. PubMed PMID: 12960087.

  95. Sullivan SD, Moenter SM. Neurosteroids alter gamma-aminobutyric acid postsynaptic currents in gonadotropin-releasing hormone neurons: a possible mechanism for direct steroidal control. Endocrinology. 2003 Oct;144(10):4366-75. PubMed PMID: 12960018.

  96. Nunemaker CS, DeFazio RA, Moenter SM. Calcium current subtypes in GnRH neurons. Biol Reprod. 2003 Dec;69(6):1914-22. PubMed PMID: 12904316.

  97. Moenter SM, DeFazio AR, Pitts GR, Nunemaker CS. Mechanisms underlying episodic gonadotropin-releasing hormone secretion. Front Neuroendocrinol. 2003 Apr;24(2):79-93. Review. PubMed PMID: 12762999.

  98. Nunemaker CS, DeFazio RA, Moenter SM. A targeted extracellular approach for recording long-term firing patterns of excitable cells: a practical guide. Biol Proced Online. 2003;5:53-62. PubMed PMID: 12734556; PubMed Central PMCID: PMC150391.

  99. Nunemaker CS, Straume M, DeFazio RA, Moenter SM. Gonadotropin-releasing hormone neurons generate interacting rhythms in multiple time domains. Endocrinology. 2003 Mar;144(3):823-31. PubMed PMID: 12586758.

  100. DeFazio RA, Heger S, Ojeda SR, Moenter SM. Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons. Mol Endocrinol. 2002 Dec;16(12):2872-91. PubMed PMID: 12456806.

  101. DeFazio RA, Moenter SM. Estradiol feedback alters potassium currents and firing properties of gonadotropin-releasing hormone neurons. Mol Endocrinol. 2002 Oct;16(10):2255-65. PubMed PMID: 12351691.

  102. Nunemaker CS, DeFazio RA, Moenter SM. Estradiol-sensitive afferents modulate long-term episodic firing patterns of GnRH neurons. Endocrinology. 2002 Jun;143(6):2284-92. PubMed PMID: 12021193.

  103. Sullivan SD, Howard LC, Clayton AH, Moenter SM. Serotonergic activation rescues reproductive function in fasted mice: does serotonin mediate the metabolic effects of leptin on reproduction? Biol Reprod. 2002 Jun;66(6):1702-6. PubMed PMID: 12021050.

  104. Nunemaker CS, DeFazio RA, Geusz ME, Herzog ED, Pitts GR, Moenter SM. Long-term recordings of networks of immortalized GnRH neurons reveal episodic patterns of electrical activity. J Neurophysiol. 2001 Jul;86(1):86-93. PubMed PMID: 11431490.

  105. Pitts GR, Nunemaker CS, Moenter SM. Cycles of transcription and translation do not comprise the gonadotropin-releasing hormone pulse generator in GT1 cells. Endocrinology. 2001 May;142(5):1858-64. PubMed PMID: 11316751.

  106. Suter KJ, Wuarin JP, Smith BN, Dudek FE, Moenter SM. Whole-cell recordings from preoptic/hypothalamic slices reveal burst firing in gonadotropin-releasing hormone neurons identified with green fluorescent protein in transgenic mice. Endocrinology. 2000 Oct;141(10):3731-6. PubMed PMID: 11014229.

  107. Suter KJ, Song WJ, Sampson TL, Wuarin JP, Saunders JT, Dudek FE, Moenter SM. Genetic targeting of green fluorescent protein to gonadotropin-releasing hormone neurons: characterization of whole-cell electrophysiological properties and morphology. Endocrinology. 2000 Jan;141(1):412-9. PubMed PMID: 10614664.

  108. Karsch FJ, Bowen JM, Caraty A, Evans NP, Moenter SM. Gonadotropin-releasing hormone requirements for ovulation. Biol Reprod. 1997 Feb;56(2):303-9. Review. PubMed PMID: 9116125.

  109. Thrun LA, Moenter SM, O'Callaghan D, Woodfill CJ, Karsch FJ. Circannual alterations in the circadian rhythm of melatonin secretion. J Biol Rhythms. 1995 Mar;10(1):42-54. PubMed PMID: 7632980.

  110. Dahl GE, Evans NP, Moenter SM, Karsch FJ. The thyroid gland is required for reproductive neuroendocrine responses to photoperiod in the ewe. Endocrinology. 1994 Jul;135(1):10-5. PubMed PMID: 8013340.

  111. Woodfill CJ, Wayne NL, Moenter SM, Karsch FJ. Photoperiodic synchronization of a circannual reproductive rhythm in sheep: identification of season-specific time cues. Biol Reprod. 1994 Apr;50(4):965-76. PubMed PMID: 8199277.

  112. Karsch FJ, Dahl GE, Evans NP, Manning JM, Mayfield KP, Moenter SM, Foster DL. Seasonal changes in gonadotropin-releasing hormone secretion in the ewe: alteration in response to the negative feedback action of estradiol. Biol Reprod. 1993 Dec;49(6):1377-83. PubMed PMID: 8286620.

  113. Moenter SM, Caraty A, Lehman MN, Karsch FJ. Characterization and regulation of pre-ovulatory secretion of gonadotrophin-releasing hormone. Hum Reprod. 1993 Nov;8 Suppl 2:51-6. Review. PubMed PMID: 8276969.

  114. Moenter SM, Karsch FJ, Lehman MN. Fos expression during the estradiol-induced gonadotropin-releasing hormone (GnRH) surge of the ewe: induction in GnRH and other neurons. Endocrinology. 1993 Aug;133(2):896-903. PubMed PMID: 8344224.

  115. Lehman MN, Ebling FJ, Moenter SM, Karsch FJ. Distribution of estrogen receptor-immunoreactive cells in the sheep brain. Endocrinology. 1993 Aug;133(2):876-86. PubMed PMID: 8344223.

  116. Kasa-Vubu JZ, Dahl GE, Evans NP, Thrun LA, Moenter SM, Padmanabhan V, Karsch FJ. Progesterone blocks the estradiol-induced gonadotropin discharge in the ewe by inhibiting the surge of gonadotropin-releasing hormone. Endocrinology. 1992 Jul;131(1):208-12. PubMed PMID: 1611998.

  117. Barrell GK, Moenter SM, Caraty A, Karsch FJ. Seasonal changes of gonadotropin-releasing hormone secretion in the ewe. Biol Reprod. 1992 Jun;46(6):1130-5. PubMed PMID: 1391310.

  118. Moenter SM, Brand RC, Karsch FJ. Dynamics of gonadotropin-releasing hormone (GnRH) secretion during the GnRH surge: insights into the mechanism of GnRH surge induction. Endocrinology. 1992 May;130(5):2978-84. PubMed PMID: 1572305.

  119. Moenter SM, Brand RM, Midgley AR, Karsch FJ. Dynamics of gonadotropin-releasing hormone release during a pulse. Endocrinology. 1992 Jan;130(1):503-10. PubMed PMID: 1727719.

  120. Webster JR, Moenter SM, Barrell GK, Lehman MN, Karsch FJ. Role of the thyroid gland in seasonal reproduction. III. Thyroidectomy blocks seasonal suppression of gonadotropin-releasing hormone secretion in sheep. Endocrinology. 1991 Sep;129(3):1635-43. PubMed PMID: 1874193.

  121. Moenter SM, Caraty A, Locatelli A, Karsch FJ. Pattern of gonadotropin-releasing hormone (GnRH) secretion leading up to ovulation in the ewe: existence of a preovulatory GnRH surge. Endocrinology. 1991 Sep;129(3):1175-82. PubMed PMID: 1874164.

  122. Webster JR, Moenter SM, Woodfill CJ, Karsch FJ. Role of the thyroid gland in seasonal reproduction. II. Thyroxine allows a season-specific suppression of gonadotropin secretion in sheep. Endocrinology. 1991 Jul;129(1):176-83. PubMed PMID: 2055181.

  123. Moenter SM, Woodfill CJ, Karsch FJ. Role of the thyroid gland in seasonal reproduction: thyroidectomy blocks seasonal suppression of reproductive neuroendocrine activity in ewes. Endocrinology. 1991 Mar;128(3):1337-44. PubMed PMID: 1999155.

  124. Moenter SM, Caraty A, Karsch FJ. The estradiol-induced surge of gonadotropin-releasing hormone in the ewe. Endocrinology. 1990 Sep;127(3):1375-84. PubMed PMID: 2201536.

  125. Karsch FJ, Moenter SM. Neuroendocrine regulation of seasonal breeding cycles in the ewe. J Exp Zool Suppl. 1990;4:17-21. Review. PubMed PMID: 1974786.

  126. Malpaux B, Moenter SM, Wayne NL, Woodfill CJ, Karsch FJ. Reproductive refractoriness of the ewe to inhibitory photoperiod is not caused by alteration of the circadian secretion of melatonin. Neuroendocrinology. 1988 Sep;48(3):264-70. PubMed PMID: 3185862.