Ahnström G, Ljungman M: Effects of 3-aminobenzamide on the rejoining of DNA strand breaks in mammalian cells exposed to methyl methanesulphonate; Role of poly(ADP-ribose) polymerase. Mutat. Res., 194:17-22, 1988.
Ljungman M: Pretreatment with UV light renders the chromatin of human fibroblasts more susceptible to the DNA-damaging agents bleomycin, gamma radiation and 8-methoxypsoralen, Carcinogenesis, 10:447-451, 1989.
Ljungman M: The role of chromatin in the induction and repair of DNA damage. Ph.D. Thesis, Stockholm University Stockholm, Sweden, 1990.
Ljungman M: The influence of chromatin structure on the frequency of radiation-induced DNA strand breaks - A study using nuclear and nucleoid monolayers. Radiat. Res. 126:58-64, 1991.
Ljungman M, Nyberg S, Nygren J, Eriksson M, Ahnström G: DNA-bound proteins contribute much more than soluble intracellular compounds to the intrinsic protection against radiation-induced DNA strand breaks in human cells. Radiat. Res., 127:171-176, 1991.
Ljungman M, Hanawalt: Efficient protection against oxidative DNA damage in chromatin. Mol. Carcinogenesis, 5:264-269, 1992.
Ljungman M, Hanawalt PC: Localized torsional tension in DNA of human cells. Proc. Natl. Acad. Sci. USA, 89:6055-6059, 1992.
Nygren J., Ljungman M, Ahnström G: Chromatin structure and radiation-induced strand breaks in human cells: Mechanism of double strand break induction. Int. J. Radiat. Biol. 68:11-18, 1995.
Ljungman M, Hanawalt PC: Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivo. Nucleic Acids Res. 23:1781-1789, 1995.
Ljungman M, Hanawalt PC: The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription. Carcinogenesis 17:31-35, 1996
Ljungman M: Effect of differential gene expression on the chromatin structure of the DHFR gene domain in vivo. Biochem. Biophys. Acta, 1307:171-177, 1996.
Ljungman M, Zhang F: Blocked RNA polymerase as a possible trigger for UV light-induced apoptosis. Oncogene 13:823-831, 1996.
Chung D, Zhang F, Chen F, McLaughlin WP and Ljungman M: Butyrate attenuates Bcl-XL expression in human fibroblasts and acts in synergy with ionizing radiation to induced apoptosis. Radiation Research 149:187-194, 1998.
McKay BC, Ljungman M and Rainbow AJ: Persistent DNA damage induced by ultraviolet light inhibits p21WAF1 expression: implications for DNA repair, UV sensitivity and the induction of apoptosis. Oncogene 17:545-555, 1998.
Ljungman M, Zhang F, Chen F, Rainbow AJ and McKay BC,: Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene 18:583-592, 1999.
Ljungman M: Recovery of RNA synthesis from the DHFR gene following UV-irradiation precedes the removal of photolesions from the transcribed strand. Carcinogenesis 20:395-399, 1999.
Chang D, Chen F, Zhang F, McKay BC and Ljungman M: Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest. Cell Growth & Differentiation 10:155-162, 1999.
McKay BC, Ljungman M and Rainbow AR: Potential roles of p53 in nucleotide excision repair. Carcinogenesis 20:1389-1396,1999.
McKay BC and Ljungman M: Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light. Neoplasia 1:276-284,1999.
Ljungman M: Repair of radiation-induced DNA strand breaks does not occur preferentially in transcriptionally active DNA. Radiation Research , 152:444-449, 1999.
Liwu Li, Ljungman M and Dixon JE: Human CDC14 phosphatases interact with and dephosphorylates the tumor suppressor protein p53 J. Biol. Chem. 275:2410-2414, 2000.
Ljungman M: Dial 9-1-1 for p53 ? Mechanisms of p53 Activation by Cellular Stress. Neoplasia 2:208-225, 2000.
Chen F, Chang D, Goh M, Klibanov S and Ljungman M: Role of p53 in cell cycle regulation and apoptosis following exposure to proteasome inhibitors. Cell Growth & Differentiation 11:239-246, 2000.
McKay BC, Chen F, Perumalswami CR, Zhang F, and Ljungman M: The tumor suppressor p53 can both stimulate and inhibit UV light-induced apoptosis. Molecular Biology of the Cell 11:2543-2551, 2000.
States JC, McGregor WG and Ljungman M: 2nd Annual Midwest DNA Repair Symposium. Mutation Research 461:163-167, 2000.
McKay BC, Chen F, Clarke ST, Wiggin HE, Harley LM and Ljungman M: UV light-induced degradation of RNA polymerase II is dependent on the Cockayne?s syndrome A and B proteins but not p53 or MLH1. Mutation Research 485:93-105, 2001.
Ljungman M: Individual variation in p53 responsiveness. J. Natl. Cancer Inst. 93:82-83, 2001.
Klibanov SA, O?Hagan HM and Ljungman M: Accumulation of soluble and nucleolar-associated p53 following cellular stress. J. Cell Sci. 114:1867-1873, 2001.
Goh M, Chen F Michelle L. TenBroeke, Dyer SE, Ann M Yeager and Ljungman M: Phenylbutyrate attenuates the expression of Bcl-XL, DNA-PK, caveolin and VEGF in prostate cancer cells. Neoplasia, 3:331-338, 2001.
Ljungman M and Paulsen MT: The Cdk inhibitor roscovitine inhibits RNA synthesis and triggers nuclear accumulation of p53 that is unmodified at ser15 and lysine382. Mol. Pharm., 60:785-789, 2001.
Ljungman M, O'Hagan HM and Paulsen MT: Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation. Oncogene, 20:5964-5971, 2001.
McKay BC, Becerril C and Ljungman M: p53 plays a protective role against UV- and cisplatin-induced apoptosis in transcription-coupled repair proficient fibroblasts. Oncogene 20:6805-6808, 2001.
Billecke CA, Ljungman M, McKay BC, Rehemtulla A, Taneja N and Ethier SP: Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells. Oncogene 21:4481-4489, 2002.
Dyer ES, Paulsen MT. Markwart SM, Goh M, Livant DL and Ljungman M: Phenylbutyrate inhibits the invasive properties of prostate and breast cancer cell lines in the Sea Urchin Embryo Basement Membrane Invasion Assay. Int. J. Cancer 101:496-499, 2002.
McKay BC, Becerril C and Ljungman M: Ultroviolet light-induced apoptosis is associated with S-phase in primary human fibroblasts. DNA Repair 1:811-820, 2002.
Yanamadala S and Ljungman M: Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates. Molecular Cancer Research, 1:747-754, 2003.
Robinson BW, Im MM, Ljungman M, Praz F, Shewach DS: Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells. Cancer Research 63:6935-6941, 2003.
O'Hagan HM and Ljungman M: Phosphorylation and nuclear accumulation are distinct events contributing to the activation of p53. Mutation Research 546:7-15, 2004.
Galigniana MD, Harrell JM, O'Hagan HM, Ljungman M and Pratt WB: Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus. J. Biol. Chem. 279:22483-22489, 2004.
O’Hagan HM and Ljungman M: Nuclear accumulation of p53 following inhibition of transcription is not due to diminished levels of MDM2. Oncogene 23:5505-5512, 2004.
O’Hagan HM and Ljungman M: Efficient Nuclear Export of NES-containing Proteins Requires Ongoing Synthesis and Export of mRNAs. Exp. Cell Res. 297:548-559, 2004.
Murphy, PJ, Galigniana, MD, Morishima, Y, Harrell, JM, Kwok, RP, Ljungman, M, Pratt, WB: Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. J. Biol. Chem. 279:30195-30201, 2004.
Ljungman M and Lane DP: Transcription - guarding the genome by sensing DNA damage Nature Reviews Cancer 4:727-737, 2004.
Paulsen MT and Ljungman M: The natural toxin juglone causes degradation of p53 and induces rapid H2AX phosphorylation and cell death in human fibroblasts. Toxicology and Applied Pharmacology, 209:1-9, 2005.
Ljungman M: Mechanisms of DNA repair: Introduction. Mutat. Res. 577:1-3, 2005.
Ljungman M: Activation of DNA damage signaling. Mutat. Res., 577:203-216, 2005.
Derheimer FA, Chang CW and Ljungman M: Inhibition of transcription as a cancer-therapeutic target. European J. Cancer, 41:2569-2576, 2005.
Elshaikh M, Ljungman M, Ten Haken R and Lichter AS: Advances in Radiation Oncology, Annual Rev. Med. 57:19-31, 2006.
Paulsen MT, Starks AM, Derheimer FA, Hanasoge S, Li L, Dixon JE and Ljungman M: The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers Molecular Cancer 5:25, June 19, 2006.
Nyati MK, Feng FY, Maheshwari D, Varambally S, Zielske SP, Ashan A, Chun PY, Arora VA, Davis MA, Jung M, Ljungman M, Canman C, Chinnaiyan AM and Lawrence TS: ATM downregulates p-ERK1/2 via activation of MKP-1 in response to radiation. Cancer Research 66:11554-11559, 2006.
Burkitt K and Ljungman M: Compromised Fanconi anemia response due to BRCA1 deficiency in cisplatin-sensitive head and neck cancer cell lines. Cancer Letters 253:131-137, 2007.
Lopez CA, Feng FY, Herman JM, Nyati MK, Lawrence TS and Ljungman M: Phenylbutyrate sensitizes human glioblastoma cells lacking wild type p53 function to ionizing radiation. Int. J. Radiat. Onc. Biol. Phys. 69:214-220, 2007.
Derheimer FA, O'Hagan HM, Krueger H, Hanasoge S, Paulsen MT and Ljungman M: RPA and ATR link transcriptional stress to p53, PNAS 104:12778-12783, 2007
Ljungman M: The transcription stress response. Cell Cycle, 6:2252-2257, 2007.
Cooper S, Paulsen M, Ljungman M, Vu-Phan D, Kim D and Gonzalez-Hernandez M: Membrane-elution analysis of content of cyclins A, B1 and E during the unperturbed mammalian cell cycle. Cell Division 2:28, 2007.
Hanasoge S and Ljungman M:: H2AX phosphorylation after UV-Irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase. Carcinogenesis, 28:2298-2304, 2007.
Salmon A, Ljungman M and Miller R: Cells from long-lived mutant mice exhibit enhanced repair of UV lesions. J. Gerontol. Biol. Sci. 63A:219-231, 2008.
Burkitt K and Ljungman M: Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin. Molecular Cancer, 7:24, 2008.
Gonzalez ME, Li X, Toy K, DuPrie M, Ventura A, Banerjee M, Ljungman M, Merajver SD and Kleer CG: Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1. Oncogene, 28:843, 2009.
Wu J, Huen MS, Lu LY, Ye L, Dou Y, Ljungman M, Chen J and Yu X: Histone ubiquitination associates with BRCA1-dependent DNA damage response. Mol. Cell. Biol., 29:849, 2009.
Derheimer FA, Hicks K, Paulsen MT, Canman C and Ljungman M: Psoralen-induced interstrand DNA cross-links block transcription and induce p53 in an ATR-dependent manner. Mol. Pharm. 75:599, 2009.
Wang L, Heidt DG, Lee CJ, Logsdon CD, Zhang L, Fearon ER, Ljungman M, and Simeone DM: Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and b-catenin stabilization. Cancer Cell, 15:207, 2009.
Dai Y, DeSano JT, Meng Y, Ji Q, Ljungman M, Lawrence TS and Xu L: Celastrol potentiates radiotherapy by impairment of DNA damage processing in human prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 74:1217, 2009.
Ljungman M: Targeting the DNA damage response in cancer. Chemical Rev., 109:2929, 2009.
Ljungman M: The DNA damage response – repair or despair? Env. Mol. Mut. 51:879-889, 2010.
Hall CL, Zhang H, Baile S, Ljungman M, Kuhstoss S, and Keller ET: Induction of p21CIP-1/WAF-1 is required for inhibition of prostate cancer growth induced by decreased DKK-1 expression. Cancer Research 70:9916-9926, 2010.
Wu J, Chen Y, Lu L-Y, Wu Y, Paulsen MT, Ljungman M, Ferguson DO and Yu X: Chfr and RNF8 synergistically regulate ATM activation, Nature Structural & Molecular Biology 18:761-768, 2011.
Ljungman M: Etiology of cancer: Physical factors. Book Chapter in “Cancer – Principles and Practice of Oncology, 9th Edition, 2011.
Fu J, Fang H, Paulsen MT, Ljungman M, Kocarek TA, and Runge-Morris M: Regulation of SULT1E1 Expression by Confluency of MCF10A Breast Epithelial Cells: Role of the Aryl Hydrocarbon Receptor, Mol. Pharmacol. 339:597-606, 2011.
Ljungman M: Transcriptional Inhibition by DNA Damage as a Trigger for Cell Death, in: The Cellular Response to Genotoxic Insults, RSC Publishing, June, 2012.
Paulsen MT, Veloso A, Prasad J, Bedi K, Ljungman EA, Tsan Y-C, Chang C-W, Tarrier B, Washburn JG, Lyons R, Robinson DR, Kumar-Sinha C, Wilson TE and Ljungman M: Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response, Proc. Natl. Acad. Sci. USA, 110:2240-2245, 2013.
Ray D , Shukla S, Allam US, , Helman A, Ramanand SG, Tran L, Bassetti M, P Krishnamurthy PM, Rumschlag M, Paulsen M, Sun L, Shanley TP, Ljungman M, Nyati MK , Zhang M, Lawrence TS: Tristetraprolin Mediates Radiation-Induced TNFa Production in Lung Macrophages, PLoS One, 8:e57290, 2013.
Wilson TE, DeMarini DM, Dertinger SD, Engelward BP, Hanawalt PC, MacGregor JT, Smith-Roe SL, Witt KL, Yauk CL, Ljungman M, Schwartz JL and Klein CB: Building on the Past, Shaping the Future: The Environmental Mutagenesis and Genomics Society, Environmental Molecular Mutagenesis, 54:153-157, 2013.
Veloso A, Biewen B, Paulsen MT, Berg N, Lima L, Prasad J, Bedi K, Magnuson B, Wilson TE and Ljungman M: Genome-Wide Transcriptional Effects of the Anti-Cancer Agent Camptothecin, PLOS One, 8:e78190, 2013.
Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D, Leflein J, Davis M, Zhang M, Tang W, Hicks JK, Helchowski CM, Prasad J, Lawrence TS, Xu L, Yu X, Canman CE, Ljungman M and Simeone DM: Phosphorylation of ATDC via ATM/ MAPKAP Kinase 2 Signaling Mediates Radioresistance of Pancreatic Cancer Cells, Cancer Research 74:1778-1788, 2014. PMCID:3961828.
Paulsen MT, Veloso A, Prasad J, Bedi K, Ljungman EA, Magnuson B, Wilson TE, Ljungman M: Use of Bru-Seq and BruChase-Seq for genome-wide assessment of the synthesis and stability of RNA, Methods, 67:45-54, 2014, PMCID:4009065.
Veloso A, Kirkconnell K, Magnuson B, Biewen B, Paulsen MT, Wilson TE and Ljungman M: Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications. Genome Research 26:896-905, 2014, PMCID:4032854.
Prensner JR, Chen W, Han S, Iyer MK, Cao Q, Evans J, Paulsen MT, Ljungman M, Lawrence TS, Chinnaiyan AM, Feng FY: The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through post-transcriptional stabilization of the cMyc oncogene, Neoplasia, 16:900-908, 2014, PMCID:. 4240923.
Svoboda L, Harris A, Bailey N, Schwentner R, Tomazou E, von Levetzow C, Magnuson B, Ljungman M, Kovar H, Lawlor ER: Over expression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs, Epigenetics, 9:1613-1625, 2014.
Ljungman M: Etiology of cancer: Physical factors. Book Chapter in “Cancer – Principles and Practice of Oncology, 10th Edition, 2015.
Wang L, Yang H, Abel EV, Ney GM, Palmbos PL, Bednar F, Zhang Y, Leflein JE, Waghray M, Palmbos P, Owens S, Wilkinson JE, Prasad J, Ljungman M, Rhim AD, Pasca di Magliano, Simeone DM: ATDC Induces an Invasive Switch in KRAS-Induced Pancreatic Tumorigenesis, Genes & Dev., 29:171-183, 2015. PMCID: 4298136
Wilson TE, Arlt MF, Park SH, Rajendran S, Paulsen MT, Ljungman M, Glover TW: Large transcription units unify copy number variants and common fragile sites occurring under replication stress, Genome Research, 25:189-200, 2015.
Buchner DA, Charrier A, Srinivasan E, Wang L, Paulsen MT, Poritsanos N, Ljungman M, Bridges D and Saltiel AR: A Targeted siRNA Screen Reveals That ZFP407 Regulates Insulin Stimulated Glucose Uptake and Glut4 mRNA J. Biol. Chem., 290:6376-6386, 2015.
Andrade-Lima LC, Veloso V, Paulsen MT, Menck CFM and Ljungman M: Delayed repair and recovery of transcription in long genes after exposure to ultraviolet light Nucleic Acids Res. 43:2744-2756, 2015.
Selvanathan SP, Graham GT, Erkizan HV, Dirksen U, Natarajan TG, Dakic A, Yu S, Liu X, Paulsen MT, Ljungman ME, Wu CH, Lawlor ER, Uren A and Toretsky JA: Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. Proc Natl Acad Sci U S A 112:E1307-16, 2015.
Chen H, Chen J, Muir L, Ronquist S, Meixner W, Ljungman M, Ried T, SmaleS and Rajapakse I: FunctionalOrganization of the Human 4D nucleome, Proc Natl Acad Sci U S A 112:8002-8007, 2015.
Andrade-Lima L, Veloso A and Ljungman M:Transcription arrest leads to new beginnings, Biomolecules, 5:1600-1617, 2015.
LefkofskyH, Veloso A and Ljungman M: Transcriptional and Post-Transcriptional Regulationof Nucleotide Excision Repair Genes in Human Cells, Mutation Research 776:9-15, 2015.
Kocab AJ, VelosoA, Paulsen MT, Ljungman M and Duckett CS: Effects of Physiological andSynthetic IAP antagonism on c-IAP-dependent signaling, Oncogene 34:5472-5481,2015.
Kuang Y, El-Khoueiry A, Taverna P, Ljungman M and Neamati N:SGI-110 priming sensitizes hepatocellular carcinoma cells to oxaliplatin, Molecular Oncology 9:1799-1814, 2015.
Muenyi CS, Ljungman M and States JC: Arsenic disruption of DNAdamage responses - potential role in carcinogenesis and chemotherapy, Biomolecules 5:2184-2193, 2015.
Yang H, Palmbos PL, Wang L, Ney G, Prasad J, Misek D, Yu X, Ljungman M, Simeone DM: ATDC (Ataxia Telangectasia GroupD Complementing) Promotes Radioresistance Through an Interaction with the RNF8ubiquitin ligase J. Biol. Chem. 290:27146-27157, 2015.
Palmbos PL, Wang L, Yang H,Leflein J, Wilkinson J, Kumar-Sinha C, Ney GM, T Detzler TA, Tomlins SA,Daignault S, Kunju LP, Wu X-R, Lotan Y, Liebert M, Ljungman M, Simeone DM: ATDC(TRIM29) Drives Invasive Bladder Cancer Formation, Cancer Research 75:5155-5166, 2015.
Magnuson B, Veloso A, Kirkconnell KS, Andrade-Lima L, Paulsen MT, Ljungman EA, Bedi K, Prasad J, Wilson TE and Ljungman M: Identifying transcription start sites and active enhancer elements using BruUV-seq, Scientific Reports 5:17978, 2015.
Kirkconnell KS, Paulsen MT, Magnusson B, Bedi K and Ljungman M: Capturing the dynamic nascent transcriptome after acute cellular responses: the serum response, Biology Open, 5:837-847, 2016
Magnuson B, Bedi K and Ljungman M: Genomic stability vs. transcript diversity, DNA Repair, 44:81-86, 2016.
Ramkumar K, Kyani A, Stuckey JA, Si Li, Chinnaswamy K, Otake H, Debnath B, Yarovenko V, Ljungman M and Neamati N: Mechanistic evaluation, crystal structure and gene expression signature of a Glutathione S-transferase Omega 1 inhibitor, Nature Communications 7:13084, 2016.
Nilotpal Roy, Kenneth K Takeuchi, Jeanine M Ruggeri, Peter Bailey, David Chang, Joey Li, Laura Leonhardt, Sapna Puri, Yan Song, Mats Ljungman, Shivani Malik, Christopher V E Wright, Eric A Collisson, David D Dawson, Andrew V Biankin, Matthias Hebrok, Howard C Crawford: PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance, Genes & Development, 30:2669-2683, 2016.
Zhang H, Gan H, Wang Z, LeeJ-H, Ordog T, Wold M, Ljungman M and Zhang Z: RPA Interacts with HIRA and Regulates H3.3 Depositionat Gene Regulatory Elements in Mammalian Cells Molecular Cell, 65:272-284, 2017.
Kirkconnell KS,Magnusson B, Paulsen MT,Bedi K and Ljungman M: Gene length as a biologicaltimer to establish temporal transcriptionalregulation, Cell Cycle, 16:259-270,2017.
Venkata Narayanan I, Paulsen MT, BediK, Berg N, Ljungman EA, FranciaS, Veloso A, Magnuson B, d'Addadi Fagagna F, Wilson TE and LjungmanM: Transcriptional and post-transcriptional regulation of the ionizingradiation response by ATM and p53, Scientific Reports, 7:43598, 2017.
Fabio Iannelli, Alessandro Galbiati, Ilaria Capozzo, Quan Nguyen,Alexander Kanitz, Brian Magnuson, Mihaela Zavolan, Sofia Francia, Nicola Crosetto, Mats Ljungman, Piero Carninci, Fabrizio d’Adda di Fagagna: A damaged genome's transcriptional landscape: multilayered expression profiling around in situ mapped DNA double-strand breaks Nature Communications 8:15656, 2017.
Frank SB, Berger PL,Ljungman M and Miranti CK: Human ProstateLuminal Cell Human Prostate Luminal Cell Differentiation requires NOTCH3Induction by p38-MAPK and MYC, Journal of Cell Science, 130:1952-1964, 2017.
Stefanie Galbán, April A. Apfelbaum,Carlos Espinoza, Kevin Heist, Henry Haley, Karan Bedi, Mats Ljungman, Craig J. Galbán, Gary D. Luker, Marcian vanDort, Brian D. Ross: A bifunctional MAPK/PI3K antagonist for inhibition oftumor growth and metastasis, Molecular Cancer Therapeutics, 16:2340-2350, 2017.
Mats Ljungman, Luke Parks, Radhika Hulbatte and Karan Bedi: The role of H3K79 methylation in transcription and the DNA damage response, Mutation Research Reviews (in press).
Anahita Kyani, Shuzo Tamura, Suhui Yang, AndreaShergalis, Soma Samanta, Yuting Kuang, Mats Ljungman, Nouri Neamati: Discovery and Mechanism Elucidation of aClass of PDI Inhibitors for the Treatment of Glioblastoma, Chem. Med. Chem. 13:164-177, 2018.
H.K. Schofield,J. Zeller, C. Espinoza, C.J. Halbrook, A. Del Vecchio, B. Magnuson, T. Fabo,A.E.C. Daylan, I. Kovalenko, H.J. Lee, W. Yan, Y. Feng, S.A. Karim, D.M.Kremer, C. Kumar-Sinha, C.A. Lyssiotis, M. Ljungman, J.P. Morton, S. Galban,E.R. Fearon, M. Pasca di Magliano, Mutant p53R270H drives altered metabolismand increased invasion in pancreatic ductal adenocarcinoma, JCI insight, 3:e97422, 2018.
Y. Kuang, M.Sechi, S. Nurra, M. Ljungman, N. Neamati, Design and Synthesis of NovelReactive Oxygen Species Inducers for the Treatment of Pancreatic DuctalAdenocarcinoma, J. Medic. Chem., 61:1576-1594, 2018.
Laurie K. Svoboda, Selina S. Teh, Samuel Kerk, Sudha Sud, Aaron Zebolsky, Sydney Treichel, Dafydd Thomas, Chris Halbrook, Ho-Joon Lee, Dan Kremer, Li Zhang, Brian Magnuson, Armand Bankhead, Mats Ljungman, Tomasz Cierpicki, Jolanta Grembecka, Costas Lyssiotis, Elizabeth R. Lawlor: Regulation of oncogenic serine biosynthesis by the menin-MLL complex in Ewing sarcoma, Journal of Pathology 245:324-336, 2018.
Yajia Zhang, Sethuramasundaram Pitchiaya, Marcin Cieślik, Yashar S. Niknafs, Jean C-Y. Tien, Yasuyuki Hosono, Matthew K. Iyer, Sahr Yazdani, Shruthi Subramanyiam, Sudhanshu K. Shukla, Xia Jiang, Lisha Wang, Tzu-Ying Liu, Michael Uhl, Alexander Gawronski, Yuanyuan Qiao, Lanbo Xiao, Saravana M. Dhanasekaran, Kristin M. Juckette, Lakshmi P. Kunju, Xuhong Cao, Utsav Patel, Mona Batish, Girish Shukla, Michelle T. Paulsen, Mats Ljungman, Hui Jiang5, Rohit Mehra, Rolf Backofen, Cenk S. Sahinalp, Sue Freier, Andy Watt, Shuling Guo, Felix Y. Feng, Rohit Malik, Arul M. Chinnaiyan, The Androgen Receptor-Regulated LncRNA Landscape Reveals a Role for ARlnc1 in Prostate Cancer Progression, Nature Genetics 50:814-824, 2018.
Tank EM, Figueroa-Romero C, Hinder LM1, Bedi K, Archbold HC, Li X, Weskamp K, Safren N, Paez-Colasante X, Pacut C, Thumma S, Paulsen M, Ljungman M, Feldman EL, and Barmada SJ: Abnormal RNA stability in amyotrophic lateral sclerosis, Nature Communications 9:2845, 2018.
Ethan V. Abel, Masashi Goto, Brian Magnuson, Saji Abraham, Nikita Ramanathan, Emily Hotaling, Anthony A. Alaniz, Chandan Kumar-Sinha, Michele L. Dziubinski, Sumithra Urs, Lidong Wang, Jiaqi Shi, Meghna Waghray, Mats Ljungman, Howard C. Crawford and Diane M. Simeone: HNF1A is a Novel Oncogene and Central Regulator of Pancreatic Cancer Stem Cells, eLife 7:e33947, 2018.
Phillip L. Palmbos, Yin Wang, Armand Bankhead, Alan Kelleher, Lidong Wang, Huibin Yang, McKenzie L. Ahmet, Samuel D. Welling, Brian Magnuson, Jacob Leflein, Ethan Abel, Michelle Cusato, Sumi Urs, Mark Day, Mats E. Ljungman, Diane M. Simeone: ATDC/TRIM29 Mediates TP63-induced Invasion in Basal Bladder Cancer. Oncogene (in press).
Yajing Liu, Wenbin Ji, Andrea Shergalis, Jiaqi Xu, Amy Delaney, Drew Calcaterra, Anupama Pal, Mats Ljungman, Nouri Neamati, Alnawaz Rehemtulla: Protein disulfide isomerase inhibition activates the unfolded protein response, decreases capacity for DNA repair, leading to radiosensitization in glioblastoma Cancer Res. (in press).
Jiao Sima, Abhijit Chakraborty, Vishnu Dileep, Marco Michalski, Juan Carlos Rivera-Mulia, Claudia Trevilla-Garcia, Kyle N. Klein, Daniel Bartlett, Brian K. Washburn, Michelle T. Paulsen, Daniel Vera, Elphège P. Nora, Katerina Kraft, Stefan Mundlos, Benoit G. Bruneau, Mats Ljungman, Peter Fraser, Ferhat Ay, David M. Gilbert: Identifying cis elements for spatiotemporal control of mammalian DNA replication, Cell (in press).