Recent Alumni

Name

Predoc/Postdoc

Title of Research Project

Current Position

Elizabeth Roberts-Kirchhoff

Postdoc

Mechanism-based inactivation of cytochromes P450 2B1, 2B4, 2B11 and 2E1 by aryl- and alkylalkynes: Mechanisms of inactivation and indentification of active site peptides and modified heme

Associate Professor of Chemistry, DetroitMercy

Kan He

Postdoc

Mechanism-based inactivation of human cytochrome P450 3A4 by naturally occurring furanocoumarins: Effects of bioavailability

Co-founder and President, Unitris Biopharma Co. Ltd, Shanghai, China

J. Robert Reed

Postdoc

Effect of cytosol on the P450-mediated metabolism of nitrosamine carcinogens: Identification of a novel Phase II reaction

Assistant Professor, LSU Medical Center

Uma Sharma

Predoc

Mechanism-based inactivation of cytochrome P450 2B1 by phencyclidine and identification of an active-site peptide

Chief Scientific Officer, MMS Holdings Inc.

Imad H. Hanna

Predoc

Effects of site-specific mutagenesis of active site residues of cytochrome P450 2B1 and 2B2 on catalysis

Fellow, Novartis Pharmaceuticals Corp

Theunis Goosen

Predoc

Mechanism-based inactivation of cytochrome P450 2B1 by isothiocyanates

Sr. Scientist, Pfizer Groton, CT

Rosa Garcia

Predoc

Mechanism-based inactivation of human cytochrome P450 2B6 by acetylenicbenzotriazoles

Senior Research Fellow, University of Colorado Health Science Center, Denver, CO

John Teiber

Predoc

Metabolic activation of nitrosodialkylamines: Identification of the P450s responsible for the formation of specific DNA adducts and their role in nitrosamine carcinogenesis

Assistant Professor, Department of Internal Medicine University of Texas Southwestern Medical School at Dallas

Kelly Regal

Postdoc

Mechanism-based inactivation of cytochromes P450 by 7-ethynylcoumarin

Sr. Research Scientist, Array Biopharma     Denver, CO

Hassan R. Dhaini

Predoc

Cytochrome P450 3A4/5: A new prognostic factor for osteosarcoma

Assistant Professor,  Facultyof Health Sciences  University of Balamand  Beirut, Lebanon

Shefali (Malhotra) Kakar
Predoc
(Co-mentor)

Mechanism underlying the "Grape-fruit juice effect: the role of 6',7'-dihydroxy- bergamottin."

Research Scientist, Novartis Pharmaceuticals Corp., Florham Park, NJ

Monica I. JushchyshynMonica

Predoc

Mechanism-based inactivation of human cytochrome P450 2B6 by phencyclidine and investigations of the identity of the covalently modified peptide

On maternity leave

Anna L. Blobaum

Predoc

The Mechanism-Based Inactivation of Cytochromes P450 2E1 and 2E1 T303A by tert-Butyl Acetylenes

Postdoctoral Fellow, Department of Biochemistry,  Vanderbilt University Nashville, TN

Linda B. von Weymarn

Postdoc

The Effects of Isothiocyanates on the Human 2A Enzymes: Potential Implications for Lung Cancer

Assistant Professor Cancer Center
University of Minnesota - Twin Cities, Minneapolis, MN

Gabriel A. Knudsen

Predoc

Mechanism-based inactivation of Cytochromes P450 2B6, 2E1, & 2A by Isothiocyanates

Assistant Research Scientist, Department of Pharmacology,  The University of Arizona  Tucson, AZ

Edith Mensah-Osman 

 Postdoc  Role of PXR in Osteosarcoma

Assistant Professor of Physiology and Pharmacology

The University of Toledo, Toledo, OH

Mohamad Shebley
Predoc

Inactivation of P450 2B enzymes by piperidinyl drugs.

Group Leader, Drug Metabolism and Pharmacokinetics, Abbott Laboratories, Abbott Park, IL

 Namandje Bumpus
 Predoc  The effects of a genetic polymorphism on the catalytic properties of human cytochrome P450 2B6

  Assistant Professor, Department of Pharmacology and Molecular Sciences, John Hopkins University School of  Medicine, Baltimore, MD.

Natasha Snider Predoc Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by cytochrome p450 enzymes

Post-doctoral fellow for Dr. M. Bishr Omary, Department of Molecular and Integrative Physiology, The University of Michigan, Ann Arbor, MI



Matthew Pratt-Hyatt

Postdoc Mechanism based inactivation of CYP2E1 by diethyldithocarbamate and effects of 3A4 polymorphism on anandamide metabolism. Post-doctoral fellow for Dr. Curtis Klaassen, Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, KS