Link to publications on pubmed


                 1.             Covarrubias S, Robinson EK, Shapleigh B, Vollmers A, Katzman S, Hanley N, Fong N, McManus MT, Carpenter SCRISPR/Cas9-based screening of long                                       noncoding RNAs (lncRNAs) in macrophages with an NF-kappa B reporter. Journal of Biological Chemistry, 2017 Dec 22;292(51):20911-20920, PMID: 29051223

                        2.                Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald KA. The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression J Immunol.                         2017 Sep 20. pii: ji1700823. doi: 10.4049/jimmunol.1700823. PubMed PMID: 28931603.

                       3.              Carpenter S AND Fitzgerald KA. Cytokines and Long noncoding RNAs. Cold Spring Harb Perspect Biol. 2017 Jul 17. pii: a028589. doi: 10.1101/cshperspect.a028589. PubMed                          PMID: 28716885.


                      1.               Carpenter S. Long noncoding RNA: Novel links between gene expression and innate immunity.  Virus research. 2016; 212:137-45. PMID: 26362525

                      2.                Carpenter S. Determining the function of long noncoding RNA in Innate Immunity. Methods in molecular biology (Clifton, N.J.). 2016; 1390:183-95. PMID: 26803630


1.               Chan J, Atianand M, Jiang Z, Carpenter S, Aiello D, Elling R, Fitzgerald KA, Caffrey DR. Cutting Edge: A Natural Antisense Transcript, AS-IL1α, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1α. Journal of Immunology. 2015 Jul 15. PMID:26179904

2.               Baum R, Sharma S,Carpenter S, Li Q, Fitzgerald KA, Marshak-Rothstein A, Gravallese EM. Cutting Edge: AIM2 and Endosomal TLRs Differentially Regulate Arthritis and Autoantibody Production in DNase II-Deficient Mice. Journal of Immunology. 2015 Feb 1;194(3):873-7. PMID:25548216.

3.               Carpenter S and Fitzgerald KA. Transcription of Inflammatory genes; long noncoding RNA and beyond. Journal of Interferon & Cytokine Research. 2014 Feb;35(2):79-88. PubMed PMCID:PMC4312878



1.              Wochal PJ, Rathinam V, Dunne A, Carlson T, Lin L, Collins M, Hall JP, Carpenter S, Katherine A. Fitzgerald and Luke A.J. O’Neill. TRIL is Essential for Cytokine Production in Brain Following Escherichia coli Infection. J Immunol. 2014 Aug 15;193(4):1911-9. (Co-senior author). PubMed PMID 25015823.

2.              Thompson MR, Sharma S, Atianand M, Jensen SB, Carpenter S, Knipe DM, Fitzgerald KA, Kurt-Jones EA. Interferon Gamma Inducible protein (IFI)16 transcriptionally regulates type I interferons and other interferon stimulated genes and controls the interferon response to both DNA and RNA viruses. J Biol Chem. 2014. PubMed PMID 25002588.

3.              Carpenter S, Ricci EP, Mercier B, Moore MJ and Fitzgerald KA. Post-transcriptional regulation of gene expression in Innate Immunity. Nature Reviews in Immunology. 2014 14(6):361-76. PubMed PMID 24854588.

4.              Hangauer M.J, Carpenter S and Michael, T. McManus. ‘Discovering the complexity of the metazoan transcriptome’. Genome Biology 2014, 15:112.



1.              Carpenter S, Aiello D, Atianand M, Ricci EP, Gandhi P, Hall LL, et al. A Long     Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes. Science. 2013. Epub 2013/08/03. doi: 10.1126/science.1240925. PubMed PMID: 23907535. PMCID PMC4376668.

2.              Doyle SL, Shirey KA, McGettrick AF, Kenny EF, Carpenter S, Caffrey BE, et al. Nuclear Factor kappaB2 p52 Protein Has a Role in Antiviral Immunity through IkappaB Kinase {epsilon}-dependent Induction of Sp1 Protein and Interleukin 15. The Journal of biological chemistry. 2013;288(35):25066-75. Epub 2013/07/23. doi: 10.1074/jbc.M113.469122. PubMed PMID: 23873932; PubMed Central PMCID: PMC3757171.

3.              Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, et al. CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation. Nature immunology. 2013;14(8):812-20. Epub 2013/07/03. doi: 10.1038/ni.2639. PubMed PMID: 23812099; PubMed Central PMCID: PMC3720827.


1.              Scharfe-Nugent A, Corr SC, Carpenter SB, Keogh L, Doyle B, Martin C, et al. TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia. J Immunol. 2012;188(11):5706-12. Epub 2012/05/01. doi: 10.4049/jimmunol.1103454. PubMed PMID: 22544937.

2.              Carpenter S, Beck-Jenson S and Fitzgerald, K.A. ‘DNA sensors and Antiviral Immune responses’, July 2012. Book Chapter from Nucleic acids and Antiviral Immunity, Landes Bioscience.


1.              Carpenter S, Wochal P, Dunne A, O'Neill LA. Toll-like receptor 3 (TLR3) signaling requires TLR4 Interactor with leucine-rich REPeats (TRIL). The Journal of biological chemistry. 2011;286(44):38795-804. Epub 2011/09/14. doi: 10.1074/jbc.M111.255893. PubMed PMID: 21911501; PubMed Central PMCID: PMC3207441. (Joint First Author)


1.              Madden SF, Carpenter SB, Jeffery IB, Bjorkbacka H, Fitzgerald KA, O'Neill LA, et al. Detecting microRNA activity from gene expression data. BMC bioinformatics. 2010;11:257. Epub 2010/05/21. doi: 10.1186/1471-2105-11-257. PubMed PMID: 20482775; PubMed Central PMCID: PMC2885376.

2.              Dunne A, Carpenter S, Brikos C, Gray P, Strelow A, Wesche H, et al. IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal). The Journal of biological chemistry. 2010;285(24):18276-82. Epub 2010/04/20. doi: 10.1074/jbc.M109.098137. PubMed PMID: 20400509; PubMed Central PMCID: PMC2881752. (Joint First Author)


1.              Carpenter S, Carlson T, Dellacasagrande J, Garcia A, Gibbons S, Hertzog P, et al. TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain. J Immunol. 2009;183(6):3989-95. Epub 2009/08/28. doi: 10.4049/jimmunol.0901518. PubMed PMID: 19710467.

2.              Carpenter S, O'Neill LA. Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins. The Biochemical journal. 2009;422(1):1-10. Epub 2009/07/25. doi: 10.1042/BJ20090616. PubMed PMID: 19627256.



1.              McCoy CE, Carpenter S, Palsson-McDermott EM, Gearing LJ, O'Neill LA. Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like receptor-3 and -4 by targeting TBK1 activation. The Journal of biological chemistry. 2008;283(21):14277-85. Epub 2008/03/22. doi: 10.1074/jbc.M709731200. PubMed PMID: 18356163.



1.              Carpenter S, O'Neill LA. How important are Toll-like receptors for antimicrobial responses? Cellular microbiology. 2007;9(8):1891-901. Epub 2007/05/25. doi: 10.1111/j.1462-5822.2007.00965.x. PubMed PMID: 17521328.