All Publications
A.L. Lie, X. Pan, E. Vaghefi, T.W. White and P.J. Donaldson (2023). Alterations in free water concentration are linked to deformation of the crystalline lens during accommodation. Ophthalmol. Sci. In Press
A.A. Giannone, C. Sellitto, B. Rosati, D. McKinnon and T.W. White (2023). Single cell RNA sequencing analysis of the early postnatal mouse lens epithelium. Invest. Ophthalmol. Vis. Sci. 64:37
X. Pan, E.R. Muir, P.J. Donaldson, C. Sellitto, K. Wang, C. Cheng, B. Pierscionek and T.W. White (2023). Age-dependent changes in the water content and optical power of the in vivo mouse lens revelaed by multi-parametric MRI and optical modelling. Invest. Ophthalmol. Vis. Sci. 64:24
T. Murata and T.W. White (2023). KID症候群の病態メカニズム (Pathological mechanism of keratitis-ichthyosis-deafness syndrome). Dermatology 4:132-137
C. Peres, C. Sellitto, C. Nardin, S. Putti, T. Orsini, F. Scavizzi, M. Raspa, F. Zonta, G. Yang, T.W. White and F. Mammano (2023). Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice. eBioMedicine 89:104453
O.E. Crouthamel, L. Li, M.T. Dilluvio and T.W. White (2023). Increased hemichannel activity displayed by a connexin43 mu-tation causing a familial connexinopathy exhibiting hypotri-chosis with follicular keratosis and hyperostosis. Int. J. Mol. Sci. 24:2222
Y. Zhou, T.M. Bennett, T.W. White, A. Shiels (2023). Charged multivesicular-body protein 4b forms complexes with gap-junction proteins during lens fiber cell differentiation. FASEB J. 37:e22801
C. Sellitto, L. Li and T.W. White (2022). Double deletion of PI3K and PTEN modifies lens postnatal growth and homeostasis. Cells. 11: 2708
A.A. Giannone, L. Li, C. Sellitto and T.W. White (2021). Physiological mechanisms regulating lens transport. Front. Physiol. 12:818649
C. Sellitto, L. Li and T.W. White (2021). Connexin hemichannel inhibition ameliorates epidermal pathology in a mouse model of keratitis ichthyosis deafness syndrome. Sci. Rep. 11:24118
A.L. Lie, X. Pan, T.W. White, P.J. Donaldson and E. Vaghefi (2021). Age-dependent changes in total and free water content of in vivo human lenses measured by magnetic resonance imaging. Invest. Ophthalmol. Vis. Sci. 62:33
P.R. Brink, V. Valiunas and T.W. White (2020). Lens connexin channels show differential permeability to signaling molecules. Int. J. Mol. Sci. 21:E6943
R. Bruzzone and T.W. White (2020). Connexin hemichannel inhibition improves skin pathology in Clouston syndrome mice. EBioMedicine 57:102856
A.L. Lie, X. Pan, T.W. White, P.J. Donaldson and E. Vaghefi (2020). Using the lens paradox to optimize an in vivo MRI-based optical model of the aging human crystalline lens. Transl. Vis. Sci. Technol. 9:39
N.A. Delamere, M. Shahidullah, R.T. Mathias, J. Gao, X. Sun, C. Sellitto and T.W. White (2020). Signaling between TRPV1/TRPV4 and intracellular hydrostatic pressure in the mouse lens. Invest. Ophthalmol. Vis. Sci. 61:58
V. Valiunas and T.W. White (2020). Connexin43 and connexin50 channels exhibit different permeability to the second messenger inositol triphosphate. Sci. Rep. 10:8744
E.R. Muir, X. Pan, P.J. Donaldson, E. Vaghefi, Z. Jiang, C. Sellitto and T.W. White (2020). Multi-parametric MRI of the physiology and optics of the in-vivo mouse lens. Magn. Reson. Imaging 70:145-154
M.Y. Lee, H.-Z. Wang, T.W. White, T. Brooks, A. Pittman, H. Halai, A. Petrova, D. Xu, S. Hart, V.A. Kinsler, and W.-L. Di (2020). Allele-specific small interfering RNA corrects aberrant cellular phenotype in keratitis-ichthyosis-deafness syndrome keratinocytes. J. Invest. Derm. 140:1035-1044
Y. Chen, J. Gao, L. Li, C. Sellitto, R.T. Mathias, P.J. Donaldson and T.W. White (2019). The ciliary muscle and zonules of Zinn modulate lens intracellular hydrostatic pressure through Transient Receptor Potential Vanilloid channels. Invest. Ophthalmol. Vis. Sci. 60:4416-4424
V. Valiunas, P.R. Brink and T.W. White (2019). Lens connexin channels have differential permeability to the second messenger cAMP. Invest. Ophthalmol. Vis. Sci. 60:3821-3829
S. Gu, S. Biswas, L. Rodriguez, Z. Li, M.A. Riquelme, W. Shi, K. Wang, T.W. White, M. Reilly, W.-K. Lo, and J.X. Jiang (2019). Connexin 50 and AQP0 are essential in maintaining organization and integrity of lens fibers. Invest. Ophthalmol. Vis. Sci. 60:4021-4032
X. Pan, A.L. Lie, T.W. White, P.J. Donaldson and E. Vaghefi (2019). Development of an in vivo magnetic resonance imaging and computer modelling platform to investigate the physiological optics of the crystallin lens. Biomed. Opt. Express 10:4462-4478
M. Srinivas, T.F. Jannace, A.G. Cocozzelli, L. Li, N. Slavi, C. Sellitto, T.W. White (2019). Connexin43 mutations linked to skin disease have augmented hemichannel activity Sci. Rep. 9:19
A.G. Cocozzelli and T.W. White (2019). Connexin 43 Mutations Lead to Increased Hemichannel Functionality in Skin Disease. Int. J. Mol. Sci. 20:6186
L. Youssefian, H. Vahidnezhad, A.H. Saeidian, H. Mahmoudi, R. Karamzadeh, A. Kariminejad, J. Huang, L. Li, T.F. Jannace, P. Fortina, S. Zeinali, T.W. White, J. Uitto (2019). A novel autosomal recessive GJB2-associated disorder: Ichthyosis follicularis, bilateral severe sensorineural hearing loss and palmoplantar keratoderma. Hum. Mutat. 40:217-229
M. Srinivas, V.K. Verselis, and T.W. White (2018). Human diseases associated with connexin mutations. Biochim. Biophys. Acta.1860:192-201
M. Delmar, D.W. Laird, C.C. Naus, M.S. Nielsen, V.K. Verselis and T.W. White (2018). Connexins and disease. Cold Spring Harb. Perspect. Biol. 10:a029348
Z. Hu, W. Shi, M.A. Riquelme, Q. Shi, S. Biswas, W.-K. Lo, T.W. White, S. Gu and J.X. Jiang (2017). Connexin 50 functions as an adhesive molecule and promotes lens cell differentiation. Sci. Rep. 7:5298
C. Sellitto, L. Li, E. Vaghefi, P.J. Donaldson, R.Z. Lin and T.W. White (2016). The phosphoinositide 3-kinase p110α catalytic subunit is required for normal lens growth. Invest. Ophthalmol. Vis. Sci. 57:3145-3151
E. Lilly, C. Sellitto, L.M. Milstone and T.W. White (2016). Connexin channels in congenital skin disorders. Sem. Cell Dev. Biol. 50:4-12
Z. Shuja, L. Li, S. Gupta, G. Meşe, and T.W. White (2016). Connexin26 mutations causing palmoplantar keratoderma and deafness interact with connexin43, modifying gap junction and hemichannel properties. J. Invest. Derm. 136:225-235
Q. Shi, S. Gu, X.S. Yu, T.W. White, E.A. Banks and J.X. Jiang (2015). Connexin Controls Cell-Cycle Exit and Cell Differentiation by Directly Promoting Cytosolic Localization and Degradation of E3 Ligase Skp2. Dev. Cell 35:483-496
J. Gao, X. Sun, T.W. White, N.A. Delamere and R.T. Mathias (2015). Feedback regulation of intracellular hydrostatic pressure in surface cells of the lens. Biophys. J. 109:1830-1839
A. Santa Cruz, G. Meşe, L.Valiuniene, P.R. Brink, T.W. White, and V. Valiunas (2015). Altered conductance and permeability of Cx40 mutations associated with atrial fibrillation. J. Gen. Physiol. 146:387-398
N.A. Levit and T.W. White (2015). Connexin hemichannels influence genetically-determined inflammatory and hyperproliferative skin diseases. Pharmacol. Res. 99:337-343
J.M. Martinez, H.-Z. Wang, R.Z. Lin, P.R. Brink, and T.W. White (2015). Differential regulation of connexin50 and connexin46 by PI3K signaling. FEBS Letters 589:1340-1345
N.A. Levit, C. Sellitto, H.-Z. Wang, L. Li, M. Srinivas, P.R. Brink, and T.W. White (2015). Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine. J. Invest. Derm. 135:1033-1042
N. Slavi, C. Rubinos, L. Li, C. Sellitto, T.W. White, R. Mathias and M. Srinivas (2014). Cx46 gap junctions provide a pathway for the transport of GSH to the lens nucleus. J. Biol. Chem. 289:32694-3270
C. Rubinos, K. Villone, P.V. Mhaske, T.W White and M. Srinivas (2014). Functional effects of Cx50 mutations associated with congenital cataracts. Am. J. Physiol. Cell Physiol. 306:C212–C220
C. Sellitto, L. Li, J. Gao, M.L. Robinson, R.Z. Lin, R.T. Mathias and T.W. White (2013). AKT activation promotes PTEN hamartoma tumor syndrome-associated cataract development. J. Clin. Invest. 123:5401–5409
J. Gao, H. Wang, X. Sun, K. Varadaraj, L. Li, T.W White and R.T Mathias (2013).The effects of age on lens transport. Invest. Ophthalmol. Vis. Sci. 54:7174-7187
P.V. Mhaske, N.A. Levit, L. Li, H.-Z. Wang, J.R. Lee, Z. Shuja, P.R. Brink, and T.W. White (2013). The human Cx26-D50A and Cx26-A88V mutations causing Keratitis-Ichthyosis-Deafness syndrome display increased hemichannel activity. Am. J. Physiol. Cell Physiol. 304:C1150–C1158
T.W. White (2013). Is half of a lens gap junction channel better than none? Focus on “Properties of two cataract associated mutations located in the N-terminus of Connexin 46” Am. J. Physiol. Cell Physiol. 304:C821-C822
C.H. Xia, B. Chang, A.M. DeRosa, C. Cheng, T.W. White and X. Gong (2012). Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2. PLoS One. 7: e52894
J. Gao, X. Sun, L. Moore, P.R Brink, T.W White and R.T Mathias (2012). The effect of size and species on lens intracellular hydrostatic pressure. Invest. Ophthalmol. Vis. Sci. 54:183-192
N.A. Levit, G. Meşe, M.-G. R. Basaly and T.W. White (2012). Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome. Biochim. Biophys. Acta 1818:2014-2019
T.W. White (2012). Connexins, cell proliferation and second messengers in the crystallin lens. J. Ophthalmic Vis. Res. 7:107-108
G. Meşe, C. Sellitto, L. Li, H.-Z. Wang, V. Valiunas, G. Richard, P.R. Brink and T.W. White (2011). The Cx26-G45E mutation displays increased hemichannel activity in a mouse model of the lethal form of keratitis-ichthyosis-deafness syndrome. Mol. Biol. Cell 22:4776-4786
J. Gao, X. Sun, L.C. Moore, T.W. White, P.R. Brink and R.T. Mathias (2011). Lens intracellular hydrostatic pressure is generated by the circulation of sodium and modulated by gap junction coupling. J. Gen. Physiol. 137:507-520
L. Ebihara, J.J. Tong, B. Vertel, T.W. White, and T.L. Chen (2011). Properties of connexin 46 hemichannels in dissociated lens fiber cells. Invest. Ophthalmol. Vis. Sci. 52:882-889
L. Li, C. Cheng, C.H. Xia, T.W. White, D.A. Fletcher and X. Gong (2010). Connexin mediated cataract prevention in mice. PLoS One 5:e12624
L. Tao, A.M. DeRosa, T.W. White and G. Valdimarsson (2010). Zebrafish Cx30.3: Identification and characterization of a gap junction gene highly expressed in the skin. Dev. Dyn. 239:2627-2636
H.A. Sánchez, G. Meşe, M. Srinivas, T.W. White and V.K. Verselis (2010). Differentially altered Ca2+ regulation and Ca2+permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause Keratitis-Ichthiosis-Deafness Syndrome. J. Gen. Physiol. 136:47-62
M. Tekin, X.-J. Xia, R. Erdenetungalag, F.B. Cengiz, T.W. White, J. Radnaabazar, B. Dangaasuren, H. Tastan, W.E. Nance, A. Pandya (2010). GJB2 mutations in Mongolia: Complex alleles, low frequency, and reduced fitness of the deaf. Ann. Hum. Genet. 74:155-164
R.T Mathias, T.W White and X. Gong (2010). Lens gap junctions in growth, differentiation and homeostasis. Physiol. Rev. 90:179-206
J.R. Lee and T.W. White (2009). Connexin26 mutations in deafness and skin disease. Expert Rev. Mol. Med. 11:e35
T. Shakespeare, C. Sellitto, L. Li, C. Rubinos, X. Gong, M. Srinivas, and T.W. White (2009). Interaction between connexin50 and mitogen-activated protein kinase signaling in lens homeostasis. Mol. Biol. Cell 20:2582-2592
J.R. Lee, A.M. DeRosa and T.W. White (2009). Connexin mutations causing skin disease and deafness increase hemichannel activity and cell death when expressed in Xenopus oocytes. J. Invest. Derm. 129:870-878
A.M. DeRosa, G. Meşe, L. Li, C. Sellitto, P.R. Brink, X. Gong and T.W. White (2009). The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium. Exp. Cell Res. 315:1063-1075
H. Wang, J. Gao, X. Sun, F.J. Martinez- Wittinghan, L. Li, K. Varadaraj, M. Farrel, V.N. Reddy, T.W. White, R.T. Mathias (2009). The effects of GPX-1 knockout on membrane transport and intracellular homeostasis in the lens. J. Mem. Biol. 227:25-37
G. Meşe, V. Valiunas, P.R. Brink and T.W. White (2008). Connexin26 deafness associated mutations show altered permeability to large cationic molecules. Am. J. Physiol. Cell Physiol. 295:C966–C974
C. Cheng, C.H. Xia, L. Li, T.W. White, J. Niimi and X. Gong (2008) Gap junction communication influences intercellular protein distribution in the lens. Exp. Eye Res. 86:966-974
G. Kanaporis, G. Meşe, L. Valiuniene, T.W. White, P.R. Brink and V. Valiunas (2008). Gap junction channels exhibit connexin-specific permeability to cyclic nucleotides. J. Gen. Physiol. 131:293-305
T.W. White, Y. Gao, L. Li, C. Sellitto, and M. Srinivas (2007). Optimal lens epithelial cell proliferation is dependent on the connexin isoform providing gap junctional coupling. Invest. Ophthalmol. Vis. Sci. 48:5630-5637
A.M. DeRosa, C.H. Xia, X. Gong and T.W. White (2007). The cataract inducing Cx50-S50P mutation dominantly alters wild-type lens connexin channel gating. J. Cell Sci. 120:4107-4116
G. Meşe, G. Richard and T.W. White (2007). Gap junctions: basic structure and function. J. Invest. Derm. 127:2516-2524
S.W. Yum, J. Zhang, V. Valiunas, G. Kanaporis, P.R. Brink, T.W. White, and S.S. Scherer (2007). Human connexin26 and connexin30 form functional heteromeric hemichannels and heterotypic channels. Am. J. Physiol. Cell Physiol. 293:C1032-C1048
D.A. Gerido, A.M. DeRosa, G. Richard and T.W. White (2007). Aberrant hemichannel properties of Cx26 mutations causing skin disease and deafness. Am. J. Physiol. Cell Physiol. 293:C337-C345
A.D. Hoptak, K.A. Klein, A.M. DeRosa, T.W. White, and M.K. Iovine (2007). Zebrafish short fin mutations in connexin43 lead to aberrant gap junctional intercellular communication. FEBS Letters 581:3297-3302
F.J. Martinez-Wittinghan, M. Srinivas, C. Sellitto, T.W. White and R.T. Mathias (2006). Mefloquine effects on the lens suggest cooperative gating of gap junction channels. J. Mem. Biol. 211:163–171
A.M. DeRosa, R. Mui, M. Srinivas and T.W. White (2006). Functional characterization of a naturally occurring Cx50 truncation. Invest. Ophthalmol. Vis. Sci. 47:4474-4481
H.-B. Zhao, T. Kikuchi, A. Ngezahayo and T.W. White (2006). Gap junctions and cochlear homeostasis. J. Mem. Biol. 209:177-186
C.H. Xia, D. Cheung, A.M. DeRosa, B. Chang, W.-K. Lo, T.W. White and X. Gong (2006). Knockin a3 (Cx46) connexin prevents severe cataracts caused by an a8 (Cx50)-G22R mutation J. Cell Sci. 119:2136-2144
J.C Hervé, P. Phelan, R. Bruzzone and T.W. White (2005). Connexins, innexins and pannexins: bridging the communication gap. Biochim. Biophys. Acta 1719:3-5
V. Valiunas, R. Mui, E. McLachlan, G. Valdimarsson P.R. Brink and T.W. White (2004). Biophysical characterization of zebrafish connexin35 hemichannels. Am. J. Physiol. Cell Physiol. 287:C1596-C1604
T.W. White, H. Wang, R. Mui, J. Litteral and P.R. Brink (2004). Cloning and functional expression of invertebrate connexins from Halocynthia pyriformis. FEBS Letters 577:42-48
C. Sellitto, L. Li, and T.W. White (2004). Connexin50 is required for normal postnatal lens cell proliferation. Invest. Ophthalmol. Vis. Sci. 45:3196-3202
G. Meşe, E. Londin, R. Mui, P.R. Brink and T.W. White (2004). Altered gating properties of functional Cx26 mutants associated with recessive non-syndromic hearing loss. Hum. Genet. 115:191-199
J. Gao, X. Sun, F.J. Martinez-Wittinghan, X. Gong, T.W. White and R.T. Mathias (2004). Connections between connexins, calcium and cataracts in the lens. J. Gen. Physiol. 124:289-300
S. Cheng, T. Shakespeare, R. Mui, T.W. White, and G. Valdimarsson (2004). Connexin48.5 is required for normal cardiovascular function and visual system development in zebrafish embryos. J. Biol. Chem. 279:36993-37003
J.R. Montgomery, T.W. White, B.L. Martin, M.L. Turner and S.M. Holland (2004). A novel connexin 26 gene mutation associated with features of the keratitis-ichthyosis-deafness syndrome and the follicular occlusion triad. J. Am. Acad. Dermatol. 51:377-382
F.J. Martinez-Wittinghan, C. Sellitto, T.W. White, R.T. Mathias, D. Paul and D.A. Goodenough (2004). Lens gap junctional coupling is modulated by connexin identity and the locus of gene expression. Invest. Ophthalmol. Vis. Sci. 45: 3629-3637
T.L. Christie, R. Mui, T.W. White and G. Valdimarsson (2004). Molecular cloning, functional analysis, and RNA expression analysis of connexin45.6: A zebrafish cardiovascular connexin. Am. J. Physiol. Heart Circ. Physiol. 286:H1623-H1632
D.A. Gerido and T.W. White (2004). Connexin disorders of the ear, skin, and lens. Biochim. Biophys. Acta 1662:159-170
E. McLachlan, T.W. White, C. Ugonabo, C. Olsen, J. Nagy and G. Valdimarsson (2003). Zebrafish Cx35: Cloning and characterization of a gap junction gene highly expressed in the retina. J. Neurosci. Res. 73:753-764
F.J. Martinez-Wittinghan, C. Sellitto, L. Li, X. Gong, P.R. Brink, R.T. Mathias and T.W. White (2003). Dominant cataracts result from incongruous mixing of wild-type lens connexins. J. Cell Biol. 161: 969-978
D.A. Gerido, C. Sellitto, L. Li and T.W. White (2003). Genetic background influences cataractogenesis, but not lens growth deficiency, in Cx50 knockout mice. Invest. Ophthalmol. Vis. Sci. 44:2669-2674
T.W. White (2003). Non-redundant gap junction functions. News Physiol Sci. 18:95-99
R. Bruzzone, V. Veronesi, D. Gomès, M. Bicego, N. Duval, S. Marlin, C. Petit, P. D'Andrea and T.W. White (2003). Loss of function and residual channel activity of connexin26 mutations associated with nonsyndromic deafness. FEBS Letters 533:79-88
T.W. White (2002). Unique and redundant connexin contributions to lens development. Science 295:319-320
T.W. White, M. Srinivas, H. Ripps, A. Trovato-Salinaro, D.F. Condorelli and R. Bruzzone (2002). Virtual cloning, functional expression and gating analysis of human connexin31.9. Am. J. Physiol. Cell Physiol. 283:C960-C970
R. Bruzzone, D. Gomès, F. Denoyelle, N. Duval, J. Perea, V. Veronesi, D. Weil, C. Petit, M-M. Gabellec, P. D'Andrea and T.W. White (2001). Functional analysis of a dominant mutation of human connexin26 associated with nonsyndromic deafness. Cell Commun. Adhes. 8:425-431
N. Belluardo, T.W. White, M. Srinivas, A. Trovato-Salinaro, H. Ripps, G. Mudò, R. Bruzzone and D.F. Condorelli (2001). Identification and functional expression of HCx31.9, a novel gap junction gene. Cell Commun. Adhes. 8:173-178
T.W. White, C. Sellitto, D.L. Paul and D.A. Goodenough (2001). Prenatal lens development in connexin43 and connexin50 double knockout mice. Invest. Ophthalmol. Vis. Sci. 42:2916-2923
F. Rouan, T.W. White, N. Brown, A.M. Taylor, T.W. Lucke, D.L. Paul, C. Munro, J. Uitto, M. Hodgins and G. Richard (2001). Trans-dominant inhibition of connexin-43 by mutant connexin-26: implications for dominant connexin disorders affecting epidermal differentiation. J. Cell Sci. 114:2105-2113
N. Cason, T.W. White, S. Cheng, D.A. Goodenough and G. Valdimarsson (2001). Molecular cloning, expression analysis and functional characterization of connexin44.1: a zebrafish lens gap junction protein. Dev. Dyn. 221:238-247
T.W. White, and R. Bruzzone (2000). Gap Junctions: Fates worse than death? Curr. Biol. 10:R685-R688
T.W. White, H. Ripps, M. Srinivas and R. Bruzzone (2000). Voltage gating properties of channels formed by a skate retinal connexin. Biol. Bull. 199:165-168
T.W. White, and R. Bruzzone (2000). Intercellular communication in the eye: clarifying the need for connexin diversity. Brain Res. Rev. 32:130-137
T.W. White (2000). Functional analysis of human Cx26 mutations associated with deafness. Brain Res. Rev. 32:181-183
M.R. Al-Ubaidi, T.W. White, H. Ripps, I. Poras, P. Avner, D. Gomès and R. Bruzzone (2000). Functional properties, developmental regulation and chromosomal localization of murine connexin36, a gap-junctional protein expressed preferentially in retina and brain. J. Neurosci. Res. 59:813-826
T.W. White and D.L. Paul (1999). Genetic diseases and gene knockouts reveal diverse connexin functions. Annu. Rev. Physiol. 61:283-310
T.W. White, M.R. Deans, J. O’Brien, M.R. Al-Ubaidi, D.A. Goodenough, H. Ripps and R. Bruzzone (1999). Functional characteristics of skate connexin35, a member of the g subfamily of connexins expressed in retinal neurons. Eur. J. Neurosci. 11:1883-1890
Y. Landesman, T.W. White, T.A. Starich, J.E. Shaw, D.A. Goodenough and D.L. Paul (1999). The C. elegans innexin-3 forms connexin-like intercellular channels. J. Cell Sci. 112:2391-2396
T.W. White, D.A. Goodenough and D.L. Paul (1998). Targeted ablation of connexin50 in mice results in microphthalmia and zonular pulverulent cataracts. J. Cell Biol. 143:815-825
T.W. White, M.R. Deans, D.P. Kelsell and D.L. Paul (1998). Connexin mutations in deafness. Nature 394:630-631
J. O’Brien, R. Bruzzone, T.W. White, M.R. Al-Ubaidi and H. Ripps (1998). Cloning and expression of two related connexins from the perch retina defines a distinct subgroup of the connexin family. J. Neurosci. 18:7625-7637
G. Richard, T.W. White, L.E. Smith, R.A. Bailey, J.G. Compton, D.L. Paul and S. Bale (1998). Functional defects of Cx26 resulting from a heterozygous missense mutation in a family with dominant deaf-mutism and palmoplantar keratoderma. Hum. Genet. 103:393-399
T.W. White, and R. Bruzzone (1996). Multiple connexin proteins in single intercellular channels: Connexin compatibility and functional consequences. J. Bioenerg. Biomembr. 28:339-350
R. Bruzzone T.W. White, and D.A. Goodenough (1996). The cellular internet: online with connexins. BioEssays 18:709-718
R. Bruzzone, T.W. White and D.L. Paul (1996). Connections with connexins: The molecular basis of direct intercellular signaling. Eur. J. Biochem. 238:1-27
J. Goliger, R. Bruzzone, T.W. White and D.L. Paul. (1996). Dominant inhibition of intercellular communication by two chimeric connexins. Clin. Exp. Pharm. Physiol. 23:1062-1067.
T.W. White, D.L. Paul, D.A. Goodenough and R. Bruzzone (1995). Functional analysis of selective interactions among rodent connexins. Mol. Biol. Cell 6:459-470
T.W. White, R. Bruzzone and D.L. Paul (1995). The connexin family of intercellular channel forming proteins. Kidney Int. 48:1148-1157
J.X. Jiang, T.W. White and D.A. Goodenough (1995). Changes in connexin expression and distribution during chick lens development. Dev. Biol. 168:649-661
R. Bruzzone, T.W. White, G. Yoshizaki, R. Patiño and D.L. Paul (1995). Intercellular channels in Teleosts: Functional characterization of two connexins from Atlantic croaker. FEBS Letters 358:301-304
T.W. White, R. Bruzzone, D.A. Goodenough and D.L. Paul (1994). Voltage gating of connexins. Nature 371:208-209
T.W. White, R. Bruzzone, S. Wolfram, D.L. Paul and D.A. Goodenough (1994). Selective interactions among the multiple connexin proteins expressed in the vertebrate lens: The second extracellular domain is a determinant of compatibility between connexins. J. Cell Biol. 125:879-892
R. Bruzzone, T.W. White, S.S. Scherer, K.H. Fischbeck and D.L. Paul (1994). Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron 13:1253-1260
J.X. Jiang, T.W. White, D.A. Goodenough and D.L. Paul (1994). Molecular cloning and functional characterization of chick lens fiber connexin 45.6. Mol. Biol. Cell 5:363-373
R. Bruzzone, T.W. White and D.L. Paul (1994). Expression of chimeric connexins reveals new properties of the formation and gating behavior of gap junction channels. J. Cell Sci. 107:955-967
E.D. Eccleston, T.W. White, J.B. Howard, and D.W. Hamilton (1994). Characterization of a cell surface glycoprotein associated with maturation of rat spermatozoa. Mol. Reprod. Dev. 37:110-119
A. Moore, K.M. Ensrud, T.W. White, C.D. Fretham, and D.W. Hamilton (1994). Rat epididymis-specific sperm maturation antigens. I. Evidence that the 26 kD 4E9 antigen found on rat caudal epididymal sperm tail is derived from a protein secreted by the epididymis. Mol. Reprod. Dev. 37:181-194
T.W. White, R. Bruzzone, D.A. Goodenough and D.L. Paul (1992). Mouse Cx50, a functional member of the connexin family of gap junction proteins, is the lens fiber protein MP70. Mol. Biol. Cell 3:711-720
A. Moore, T.W. White, K.M. Ensrud, and D.W. Hamilton (1989). The major maturation glycoprotein found on rat cauda epididymal sperm is linked to the membrane via phosphatidylinositol. Biochem. Biophys. Res. Comm. 160:460-468