Dr Agam P. Singh
Head of the Lab
Oocyst ( in Mosquito ): In the middle a single midgut loaded with oocysts (Oocysts are false colored blue)
On right side. Oocyst (SEM)
source: science photo library
Liver stage exported proteins (ex. SLTRIP)
Image Source: Agam P. Singh, NII, INDIA
A Single Malaria sporozoite
Sporozoite proteins
Source: Prudencio M, IMM Purtgal
Malaria Sporozoite entering into a liver cell
Image courtesy of Volker Brinkmann
VACCINE TARGETS
1- Pre-erythrocytic / liver stage
2-Erythrocytic / blood stage
3-Transmission blocking / mosquito stage
image source: Lancet
Vaccines. targets and modes of action
Image Source: Eleanor M Riley & V Ann Stewart
Nature Medicine 19, 168–178 (2013)