Grants

Grants as Principal Investigator

• Next-Generation Bioinformatics for Next-Generation Sequencing

  • 2014/09/10-2017/06/30

  • R01 HG008115-02, National Human Genome Research Institute (NHGRI)

  • Zhang, Kui (PI), Zhi, Degui (PI), Yu, Fuli (Contact PI)

  • Role: PI

  • To develop statistical and computational methods for the analysis of NGS data.

• Haplotype Analysis in Linkage Disequilibrium Mapping

  • 2006/07/01-2012/06/30

  • R01 GM074913-05, National Institute of General Medical Sciences (NIGMS)

  • Zhang, Kui (Contact PI)

  • Role: PI

  • To develop association methods based on haplotypes for mapping genes that are responsible for complex human diseases.

• Haplotype analysis of population and pedigree data in association studies

  • 2007/09/27-2008/08/31

  • R13 HG004593-01, National Human Genome Research Institute (NHGRI)

  • Zhang, Kui (Contact PI)

  • Role: PI

  • To organize a scientific meeting to discuss the haplotype analysis in association studies.

Grants as Co-Investigator (Selected)

• Positional Gene Identification of Complex Traits

  • 2003/08/01-2006/06/30

  • R01 ES09912, National Institute of Environmental Health Sciences (NIEHS)

  • PI: Christopher Amos

  • Role: Co-Investigator

  • To develop linkage/linkage disequilibrium methods for testing the effects of quantitative trait loci on complex quantitative traits

• Chromosome 6p21-24 Markers in HIV-Related Kaposi Sarcoma

  • 2004/07/01-2008/06/30

  • R01-CA-106168, National Cancer Institute (NCI)

  • PI: Richard Kaslow

  • Role: Co-Investigator

  • To search beyond the reported associations of HLA class II alleles with HIV-KS for alternative genetic determinants within and telomeric to the HLA complex

• Population Genetics Analysis Program: Immunity to Vaccines/Infections

  • 2004/09/01-2010/08/31

  • R01 AI40068, National Institute of Allergy and Infectious Diseases (NIAID)

  • PI: Richard Kaslow

  • Role: Co-Investigator

  • To identify host genetic characteristics that determine and predict the variability in antibody responses and adverse reactions to anthrax vaccine (AVA)

• CTL and HIV Polymorphisms in Heterosexual Transmission

  • 2004/12/01-2015/03/31

  • R01 AI064060, National Institute of Allergy and Infectious Diseases (NIAID)

  • PI: Richard Kaslow

  • Role: Co-Investigator

  • To study CTL and HIV polymorphisms in heterosexual transmission

• Heterogeneity in Cytokine Responses to HIV-1 Infection

  • 2007/07/01-2009/06/30

  • K02 AI76123, National Institute of Allergy and Infectious Diseases (NIAID)

  • PI: Jianmin Tang

  • Role:Co-Investigator

  • The major goal is to study the cytokine responses to HIV-1 infection

• Haplotyping and QTL Mapping in Pedigrees with Missing Data

  • 2007/07/01-2009/10/30

  • R01 GM073766, National Institute of General Medical Sciences (NIGMS)

  • PI: Guimin Gao

  • Role:Co-Investigator

  • The major goal is to develop haplotyping and IBD probability estimation methods for large pedigrees with large numbers of loci and with missing marker data

• Genome Wide Haplotype Association Analysis

  • 2008/04/01-2014/03/31

  • R01 GM081488, National Institute of General Medical Sciences (NIGMS)

  • PI: Nianjun Liu

  • Role: Co-Investigator

  • To develop novel statistical and computational methods and software tools for the analysis of haplotypes in mapping of complex human disease genes, especially in the presence of missing genotypes and genotyping errors and with large number of markers

• Genetic Determinants of Uterine Fibroids in African-American and Caucasian Women

  • 2010/04/01-2014/03/31

  • R01 HD064398, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  • PI: Brahim Aissani

  • The major goal of this project is to dissect the genetic architecture of a subregion of human chromosome 1q43 associated with rare familial syndromes of uterine leiomyomas (fibroids) to evaluate its effects on the population risk

  • Role: Co-Investigator

• Detection of multifactor interactions with application to nicotine dependence

  • 2011/01/01-2014/03/31

  • R01 DA025095, National Institute on Drug Abuse (NIDA)

  • PI: Xiangyang Lou

  • Role: Co-Investigator

  • The major goal of this project is to develop new method (GMDR) and computer software for identifying gene-gene and gene-environment interactions underlying complex diseases and to detect interactive susceptibility loci or genes for nicotine dependence in cigarette smokers

• Genomic Surveillance and Epidemiology in the Upper Peninsula

• 2021/10/01-2024/07/31

• MI-SAPPHIRE (Michigan Sequencing Academic Partnership for Public Health Innovation and Response): State of Michigan Department of Health and Human Services

• PI: Caryn Heldt

• Role: Co-Investigator

• To develop genomic surveillance tools and methods to monitor virus infection in the Upper Peninsula.