Laboratory Chemical Safety

Reproductive hazard statement FOR LABORATORY SYLLABUS

NOTE: All science laboratory class syllabuses are required to include the reproductive hazard warning statement provided by the VPAA's office.

Chemical Safety Regulations

OSHA Regulation 29 CFR 1910.1450 - Occupational Exposure to Hazardous Chemicals in Laboratories

NJ Hazardous Waste Regulations

Guidance Documents

OSHA Laboratory Safety Guidance

Prudent Practices in the Laboratory, National Academies Press

Chemical Management

Laboratory Safety and Security, National Research Council

Cryogen Safety

Cryogen Safety, National Institutes of Standards and Technology (.gov)

Chemical-Specific Information

• NJ Right to Know Hazardous Substance Factsheets

• Safety Data Sheets at Vermont Safety Information Resources, Inc.

• PubChem at the NIH

• Toxic Substances Portal - CDC Agency for Toxic Substances and Disease Registry

Reproductive Hazards

• Reproductive Hazards - OSHA Topic Page

• The Effects of Workplace Hazards on Female Reproductive Health - CDC

• The Effects of Workplace Hazards on Male Reproductive Health - CDC

Carcinogens

Select Carcinogen, as defined by OSHA, means any substance which meets one of the following criteria: 

(i) It is regulated by OSHA as a carcinogen;  

• • 1910.1001, Asbestos [related topic page]

  • 1910.1003, 4-Nitrobiphenyl, Chemical Abstracts Service Register Number (CAS No.) 92933;alpha-Naphthylamine, CAS No. 134327; methyl chloromethyl ether, CAS No. 107302; 3,3'-Dichlorobenzidine (and its salts) CAS No. 91941; bis-Chloromethyl ether, CAS No. 542881; beta-Naphthylamine, CAS No. 91598; Benzidine, CAS No. 92875; 4-Aminodiphenyl, CAS No. 92671; Ethyleneimine, CAS No. 151564; beta-Propiolactone, CAS No. 57578; 2-Acetylaminofluorene, CAS No. 53963; 4-Dimethylaminoazo-benzene, CAS No. 60117; and N-Nitrosodimethylamine, CAS No. 62759.

  • 1910.1004, alpha-Naphthylamine 

  • 1910.1006, Methyl chloromethyl ether

  • 1910.1007, 3,3'-Dichlorobenzidine (and its salts)

  • 1910.1008, bis-Chloromethyl ether

  • 1910.1009, beta-Naphthylamine

  • 1910.1010, Benzidine

  • 1910.1011, 4-Aminodiphenyl

  • 1910.1012, Ethyleneimine

  • 1910.1013, beta-Propiolactone

  • 1910.1014, 2-Acetylaminofluorene

  • 1910.1015, 4-Dimethylaminoazobenzene

  • 1910.1016, N-Nitrosodimethylamine

  • 1910.1017, Vinyl chloride

  • 1910.1018, Inorganic arsenic [related topic page]

  • 1910.1026, Chromium (VI) [related topic page]

  • 1910.1027, Cadmium [related topic page]

  • 1910.1028, Benzene [related topic page]

  • 1910.1029, Coke oven emissions

  • 1910.1044, 1,2-dibromo-3-chloropropane

  • 1910.1045, Acrylonitrile

  • 1910.1047, Ethylene oxide [related topic page]

  • 1910.1048, Formaldehyde [related topic page]

  • 1910.1050, Methylenedianiline

  • 1910.1051, 1,3-Butadiene [related topic page]

  • 1910.1052, Methylene chloride [related topic page]) 

or

(ii) It is listed under the category, "known to be carcinogens," in the Annual Report on Carcinogens published by the National Toxicology Program (NTP) (latest edition); or

(iii) It is listed under Group 1 ("carcinogenic to humans") by the International Agency for Research on Cancer Monographs (IARC) (latest editions); or 

(iv) It is listed in either Group 2A or 2B by IARC or under the category, "reasonably anticipated to be carcinogens" by NTP, and causes statistically significant tumor incidence in experimental animals in accordance with any of the following criteria: 

     (A) After inhalation exposure of 6–7 hours per day, 5 days per week, for a significant portion of a lifetime to dosages of less than 10 mg/m3; 

     (B) After repeated skin application of less than 300 (mg/kg of body weight) per week; or 

     (C) After oral dosages of less than 50 mg/kg of body weight per day.

Substances Known or Reasonably Anticipated  to be Carcinogens

 Carcinogens listed in the 15th Report on Carcinogens, National Institutes of Health