Publications

Nyamwihura, R.J., Zhang, H., Collins, J.T., Crown, O. and Ogungbe, I.V., 2021. Nopol-Based Quinoline Derivatives as Antiplasmodial Agents. Molecules, 26(4), p.1008.

Santos CC, Zhang H, Batista MM, de Oliveira GM, Demarque KC, da Silva-Gomes NL, Moreira OC, Ogungbe IV, Soeiro MNC. In vitro and in vivo evaluation of an adamantyl-based phenyl sulfonyl acetamide against cutaneous leishmaniasis models of L. amazonensis. Antimicrob Agents Chemother. 2020. AAC.01188-20. doi: 10.1128/AAC.01188-20.

Zhang H, Harmon M, Radoshitzky S, Soloveva V, Kane C, Duplantier AJ, Ogungbe IV. Vinyl Sulfone-Based Inhibitors of Non-Structural Protein 2 Block the Replication of Venezuelan Equine Encephalitis Virus. ACS Medicinal Chemistry Letters. 2020. https://doi.org/10.1021/acsmedchemlett.0c00215

Zhang H, Collins J, Nyamwihura R, Crown O, Ajayi O, Ogungbe IV. Vinyl Sulfone-based Inhibitors of Trypanosomal Cysteine Protease Rhodesain with Improved Antitrypanosomal Activities. Bioorganic & Medicinal Chemistry Letters. 2020 Apr 28:127217.

Zhao S, Pan L, Zhang H, Zhao J, Ogungbe IV, Liu YM. A Novel One Pot Fluorescence Derivatization Strategy for Highly Sensitive MicroRNA Analysis. Chemistry–A European Journal. 2020, 26, 5639-5647.

Zhang H, Collins J, Nyamwihura R, Ware S, Kaiser M, Ogungbe IV. Discovery of a quinoline-based phenyl sulfone derivative as an antitrypanosomal agent. Bioorg. Med. Chem. Lett. (2018), 28(9):1647-1651. https://doi.org/10.1016/j.bmcl.2018.03.039

Carothers S, Nyamwihura R, Collins J, Zhang H, Park H, Setzer WN, Ogungbe IV. Bauerenol Acetate, the Pentacyclic Triterpenoid from Tabernaemontana longipes, is an Antitrypanosomal Agent. Molecules. 2018; 23(2).

Ogungbe IV, Setzer WN. The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases—Part III: In-silico molecular docking investigations. Molecules. 2016 Oct 19;21(10):1389.

McShan D, Kathman S, Lowe B, Xu Z, Zhan J, Statsyuk A, Ogungbe IV. Identification of non-peptidic cysteine reactive fragments as inhibitors of cysteine protease rhodesain. Bioorganic & Medicinal Chemistry Letters (2015), 25(20):4509-12

Jefferson T, McShan D, Warfield J, Ogungbe IV. Screening and Identification of Inhibitors of Trypanosoma brucei Cathepsin L with Antitrypanosomal Activity. Chemical Biology & Drug Design (2015), doi: 10.1111/cbdd.12628.

Warfield J, Setzer WN, Ogungbe IV. Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens. SpringerPlus 2014, 3(1), 679.

DOI: 10.1186/2193-1801-3-679

Harrison N, Lone MA, Kaul TK, Reis Rodrigues P, Ogungbe IV, Gill MS. Characterization of N-Acyl Phosphatidylethanolamine-Specific Phospholipase-D Isoforms in the Nematode Caenorhabditis elegans. PLoS One. 2014; 9(11):e113007. doi: 10.1371/journal.pone.0113007.

DOI: 10.1021/ci500537e

Kaul TK, Reis Rodrigues P, Ogungbe IV, Kapahi P, Gill MS. Bacterial fatty acids enhance recovery from the dauer larva in Caenorhabditis elegans. PLoS One. 2014; 9(1):e86979. doi: 10.1371/journal.pone.0086979.

DOI: 10.1371/journal.pone.0086979

Ogungbe IV, Erwin WR, Setzer WN. Antileishmanial phytochemical phenolics: molecular docking to potential protein targets. J Mol Graph Model. 2014; 48:105-17. doi: 10.1016/j.jmgm.2013.12.010.

Ogungbe IV, Ng JD, Setzer WN. Interactions of antiparasitic alkaloids with Leishmania protein targets: a molecular docking analysis. Future Med Chem. 2013; 5(15):1777-99. doi: 10.4155/fmc.13.114.

Ogungbe IV, Setzer WN. In-silico Leishmania target selectivity of antiparasitic terpenoids. Molecules. 2013 Jul 3;18(7):7761-847. doi: 10.3390/molecules18077761.

Setzer WN, Ogungbe IV. In-silico investigation of antitrypanosomal phytochemicals from Nigerian medicinal plants. PLoS Negl Trop Dis. 2012; 6(7):e1727. doi: 10.1371/journal.pntd.0001727.

Schmidt TJ, Khalid SA, Romanha AJ, Alves TM, Biavatti MW, Brun R, Da Costa FB, de Castro SL, Ferreira VF, de Lacerda MV, Lago JH, Leon LL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Scotti MT, Setzer WN, de N C Soeiro M, Steindel M, Tempone AG. The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part II. Curr Med Chem.

2012; 19(14):2176-228. Review.

Schmidt TJ, Khalid SA, Romanha AJ, Alves TM, Biavatti MW, Brun R, Da Costa FB, de Castro SL, Ferreira VF, de Lacerda MV, Lago JH, Leon LL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Scotti MT, Setzer WN, de N C Soeiro M, Steindel M, Tempone AG. The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I. Curr Med Chem.

2012; 19(14):2128-75. Review.

Ogungbe IV, Hill GM, Crouch RA, Vogler B, Nagarkoti M, Haber WA, Setzer WN. Prenylated isoflavonoids from Rhynchosia edulis. Nat Prod Commun. 2011; 6(11):1637-44.

Harris SM, McFeeters H, Ogungbe IV, Cruz-Vera LR, Setzer WN, Jackes BR, McFeeters RL. Peptidyl-tRNA hydrolase screening combined with molecular docking reveals the antibiotic potential of Syzygium johnsonii bark extract. Nat Prod Commun. 2011 ; 6(10):1421-4.

Helms KM, Wilson RC, Ogungbe IV, Setzer WN, Twigg PD. Vitexin inhibits polyubiquitin synthesis by the ubiquitin-conjugating enzyme E2-25K. Nat Prod Commun. 2011; 6(10):1411-6.

Ogungbe IV, Crouch RA, Haber WA, Setzer WN. Phytochemical investigation of Verbesina turbacensis Kunth: trypanosome cysteine protease inhibition by (-)-bornyl esters. Nat Prod Commun. 2010; 5(8):1161-6.

Ogungbe IV, Setzer WN. Comparative molecular docking of antitrypanosomal natural products into multiple Trypanosoma brucei drug targets. Molecules. 2009; 14(4):1513-36. doi: 10.3390/molecules14041513.