Technologies

PBR

Plug-&-Play & Reduce your Carbon Footprint

Flashlight Superhelical PhotoBioreactor (FSPBR Proprietary) & Bioreactor:

This invention is capable of enhancing the production of biomolecules by upto 500x times, with a much less requirement of space. Ideal for lab or pilot scale production of biochemical production and can also be scaled up for outdoor facility for full-blown production. This patent serves as a demonstration of what is possible, and a lot of the devil lies in the details, that are not written down in patent draft.

The present invention proposes to meet the long standing need for a Bio-reactors for the laboratory scale and mass cultivation of photosynthetic organisms such as spirulina and many other micro algae. The bioreactor comprises a system of coaxial helical transparent autoclavable tubular coils for flow of a culture medium containing microalgae to be cultivated. The annular spaces between the adjacent coils and the space enclosed by innermost coil are provided with means of providing predetermined alternate periods of light and darkness on the inner and outer surfaces of each of said coil and for temperature control of the medium to improve photosynthetic performance. The tubular coils have high surface area to volume ratio for extensive dissolution of the carbon-dioxide gas injected into the media. One of the application could be for cultivating biomass suitable for producing bio-diesel, the organism used can be say blue-green microalgae.


(1) high quality tubular photobioreactors (simple to operate, high productivity, low fouling, low OPEX, and online measurement of pH, temperature, and light)

(2) Cultivating microalgae as a sustainable biobased manufacturing process for the food, feed, biofertiliser and nutraceutical markets

(3) Consulting for algae, fermentation, bioprocess

(4) Bringing automation to the microalgal sector to make microalgae cost competitive to other platforms

(5) de-risking facility for clients to test their species before moving to industrial scale


More:

1. Novel process for flow-profile in PlugFlow for enhanced mixing and thus reduction in Retention Time

2. Amplified light reaction productivity.

3. Walls of the photostage never getting blocked by algae (no biofouling).

4. Efficient distribution of light due to high surface to volume ratio and strategic location of light distribution (Energy efficient)

5. Automated operation for consistent yield (Machine learning algorithm deployed)

6. No Contamination problem

7. Enhanced CO2 absorption (advanced technology)

8. Oxygen accumulation problem solved! (Design)

9. Highly Scalable to larger volumes (5 - 500,000 litres capacity)

10. Automated lipid extraction and conversion to oil (chemical technology)

11. Medium scale initial capital cost. Cost of land reduced when compared to raceway ponds or other photobioreactor systems. Water and solvent cost reduced.

12. Low cost of operation, and low cost of raw materials

Allosteric Deregulation for better control of Metabolic flux:

PBR Patent

This patent serves just as a demo, as the devil of details are not released in the patent draft. The reaction can be enhanced for its metabolic flux rate as much as desired at the micro cellular compartmental reaction.

A method to bypass allosteric domain activity of an enzyme so as to alter the feedback/ feed-forward inhibition/ activation, comprises of (i) a method of increasing the downstream metabolic product such as in fermentation or for genetically modified crop, where the wild type organism is feedback or feed-forward inhibited at one of its enzymatic reaction by introducing transgene to be expressed in a common cellular compartment such as cytosol and (ii) a method of dcreasing the downstream metabolic product such as for therapeutic purpose, such as controlling the uncontrolled growth of tumor, where the wild type organism is feedback or feed-forward activated at one of its enzymatic reactin, by intrducing transgene t be expressed in a common cellular compartmnet cytosol for that enzyme.

Metabolic Flux Control