Clinical Pearls
Diabetes Mellitus is one of the most important concepts in medicine to have a good grasp on, as so many people in the US have it
Quite literally, nearly every person in the US has at least one family member with the disease
Subsequently, it is imperative that you have a good working knowledge of it, not only for your success at HEA, but also for your future in medicine
Diabetic eye changes are a large part of what we see here at HEA!
Diabetes has 2 major types
1) Diabetes Mellitus Type 1 (AKA: "DM 1" or "DM I")
Insulin Deficient/Dependant
These patients have the beta cells in their pancreas destroyed usually from autoimmune disease, and therefore, cannot produce insulin
2) Diabetes Mellitus Type 2 (AKA: DM 2 or DM II)
Insulin Resistance
This is the most common type and the most important to understand!
There is so much insulin in the blood for years on end, that eventually, insulin receptors on cells surface suffer a "burnout effect" and no longer respond to it
DM 2 can have elements of insulin deficiency involved, but is mostly insulin resistant
Diabetic Eye Exam
Any patient that has diabetes needs the following documented at the bottom of the intake for the day
1) Hemoglobin A1c ("HbA1c" or "A1c")
This is one of the most important lab values in a diabetic patient! It is the gold standard for monitoring a patient's diabetes.
It is a measure of the percentage of glucose that is bound to hemoglobin in the blood over a 2-3 month period (the lifecycle of an Erythrocyte).
This essentially gives us a look at how well a patient's blood sugar has been controlled over this period.
Every person has a normal amount (less than 6.5%) but values above this are suspicious for type 2 Diabetes
Ask the patient when their last A1C was and what the value was. If they do not know, then document this
2) Fasting Blood Sugar (FBS)
This value is indicative of a person's blood glucose after an 8- 12 hour fast. This is usually done right in the morning before consuming anything.
Values above 100 mg/DL could indicate diabetes or pre- diabetes, but HbA1c is still the best for monitoring a patient's diabetes
Many people have a continuous glucose monitor embedded into the back of their arms
Ask the patient when their last FBS was and what the value was. If they do not know, then document this
Our goal in ophthalmology & medicine is to prevent diabetic retinopathy from occurring, in addition to the other bad things, like heart disease, stroke, and death!
Once any of the above has already happened, it is already too late!
Management consists of controlling of blood sugar through diet modification, exercise, and medication if needed
Please click on Diabetic Retinopathy to learn about this more in detail
Common Diabetes Medications
Metformin
First line therapy for DM 2!
It improves sensitivity to insulin and decreases glucose production
Glimepiride / Glyburide
Sulfonylureas
Stimulate insulin release by the pancreas
Mounjaro
Monoclonal antibody
Increases insulin sensitivity and release
Describe what DM 1 is?
Describe what DM 2 is?
True or False: Type 2 Diabetes is the most common type
What is HbA1C?
What is FBS?
You ask a patient about their FBS and they said they checked last night and it was 140. What do you tell them?
A patient says their diabetes medication starts with an "M", but doesn't remember the name. What is it most likely?