Research

I) Synthesis of molecular sensors and its applications in recognition of anions, cations, glucose and toxins.

Novel sesnsors (mono, bi and tri-dentate) ligand’s will be synthesized by using a greener technology to selectively sense and recognized various ions, glucose and toxins.

Publications:

Aiken, K. A.; Bunn, J.; Sutton, S.; Christianson, M.; Winder, D.; Freeman, C.; Padgett, C.; McMillen, C.; Ghosh, D.;* Landge, S.M.* "Nuclear Magnetic Resonance SpectroscopyInvestigations of Naphthalene-Based 1,2,3-Triazole Systems for Anion Sensing", Magnetochemistry, 2018, 4, 15.

Ghosh, D.; Rhodes, S.; Winder, D.; Atkinson, A.; Gibson, J.; Ming, W.; Padgett, C.; Landge, S. M.* Aiken, K.*“Spectroscopic Investigation of Bis-Appended 1,2,3-Triazole Probe for the Detection of Cu(II) Ion” J. Mol. Struct., 2017, 1134, 638-648.

Ghosh, D.; Rhodes, S.; Hawkins, K. V.; Winder, D.; Atkinson, A.; Ming, W.; Padgett, C.; Orvis, J.; Aiken, K.; Landge, S. M.* “A simple and effective 1,2,3-triazole based “turn-on” fluorescence sensor for the detection of anions” New J. Chem., 2015, 39, 295-303.

II) Development of biologically active heterocyclic compounds using greener methods such as “microwaves”.

Microwave-assisted organic synthesis (MAOS) has become extremely popular in the last two decades due to the unique applications associated with it. We are utilizing the microwave energy for the synthesis of biologically active heterocyclic compounds which has shown potential activity towards cancer and Alzheimers.

Publications:

Schäfer, C.; Ellstrom, C. J.; Sood, A.; Alonzo, J.; Landge, S. M.; Tran, D. C.; Török, B. “Environmentally Benign, Microwave-Assisted Chemoselective N-Hydroxyalkylationof Indoles with Trifluoroacetaldehyde Methyl Hemiacetal”, (Invited Article) Arkivoc, 2018, ii, 122-130. [Commemorative Issue in Honor of Kenneth K. Laali on the occasion of his 65th anniversary]

Peerannawar, S.; Sood, A.; Brown, A.; Schäfer, C.; Alonzo, J.; Sutton, S.; Christianson, M.; Stocking, R.; Naclerio, N.; Török, B.;* Landge, S. M.* 2018, “Effect of solvent polarity on the regioselective hydroxyalkylation of indole with trifluoroacetaldehyde hemiacetals” (Submitted for publication)

IV) Applying cognitive science to study how students develop an understanding of chemistry and to increase student motivation.

Our project deals with the study of thinking patterns of students when a novel scenario is placed in front of them that challenges them to make decisions based on their current knowledge of chemistry. 

Recent research indicates that students are adopting a consumerist approach to education, while data shows that the best academic outcomes are associated with intrinsic motivation. The goal of the study was to explore student academic motivation in an undergraduate Principles of Chemistry I class. Student academic motivation was measured using the adapted Academic Motivation Scale (AMS).

Publications:

Orvis, J.; Struges, D.; Tysinger, D. P. Riggins, K.; Landge, S. M. “A Culture of Extrinsically Motivated Students: Chemistry”, J. Scholarship of Teaching and Learning, 2018, 18, 1, 43-57.

V) Interdisciplinary Projects:

Various projects were carried out with different departments as a consultant and as a collaborator (within department).

Publications:

Landge, S. M.;* Ghosh, D.; Aiken, K. “Solvent Free Synthesis of Nanoparticles” 2017, Green Chemistry: An Inclusive Approach, Ed: B. Török, T. Dransfield, Elsevier, chapter 3.17 pp: 609-646. 

Williford, T.; Collins, A.; Landge, S. M. Wang, H “Labeling and comparison of isomerictree-like polyphenyl systems” J. Math. Sci.: Adv. and App. 2015, 32, 37-56.

Landge, S. M.; Török, B. “Stereoselective Synthesis ofα-Fluoro-β-Trifluromethyl-α-β-Unsaturated Esters by Horner-Wadsworth-Emmons Coupling.” (Invited article) Lett. Org. Chem. 2014 , 11, 1-6.

Patel, B.; Patel, M.; Bassett, M.; Landge, S. M.; Huang, X.; Jiang, H.; Wu, J. “Ionic Rectificationvia the Formation of Complexes orPrecipitation in Carbon Nanotube Membranes.”Chem. Lett. 2013, 42 (10), 1173-1175.                                                                                                              

 Images from cem.com, librarypress.com and microsoft.com

"The content of personal and other unofficial home pages is not sanctioned by Georgia Southern University and does not represent official information or opinions of the University. Shainaz Landge (slandge@georgiasouthern.edu) is solely responsible for the contents of this page."