Publications

PEER-REVIEWED JOURNALS 

2023

1. Yen, Yi-Kuang*, Guang-Wei Huang, and Ragurethinam Shanmugam. "Laser-scribing graphene-based electrochemical biosensing devices for simultaneous detection of multiple cancer biomarkers." Talanta (2023) Volume 266, Part 2, 125096, https://doi.org/10.1016/j.talanta.2023.125096 (Corresponding).[SCIE, IF 6.1]

2. Ya-Shin Yeh, Yi-Kuang Yen*, Ragurethinam Shanmugam ,  "Tungsten disulfide nanotubes enhanced nanocomposite paper-based aptasensor for label-free electrochemical detection of interferon-gamma, " Microchemical Journal (2023), Volume 193, 109081, https://doi.org/10.1016/j.microc.2023.109081. (Corresponding) [SCIE, IF 4.8]

2022

3. Rajesh Madhuvilakku and Yi-Kuang Yen*,  "Self-affinity of AuNPs on polyethyleneimine (PEI) functionalized polypyrrole-derived carbon nanotubes hybrid nanocomposite: A novel interference-free electrochemical sensing platform for caffeine detection, " Journal of Electroanalytical Chemistry (2022) Vol.924, 116882, https://doi.org/10.1016/j.jelechem.2022.116882. (Corresponding)[SCIE, IF 4.5]

4. Londhe A. Machhindra and Yi-Kuang Yen* "A Highly Sensitive Ele,ctrochemical Sensor for Cd2+ Detection Based on Prussian Blue-PEDOT-Loaded Laser-Scribed Graphene-Modified Glassy Carbon Electrode, " Chemosensors. (2022), 10(6):209. https://doi.org/10.3390/chemosensors10060209 .(Corresponding)

5. Rajesh Madhuvilakku, Yi-Kuang Yen*, Wei-Mon Yan, and Guang-Wei Huang, "Laser-scribed Graphene Electrodes Functionalized with Nafion/Fe3O4 Nanohybrids for the Ultrasensitive Detection of Neurotoxin Drug Clioquinol, " ACS Omega (2022), 7 (18), 15936-15950. Publication Date:April 29, 2022, https://doi.org/10.1021/acsomega.2c01069. (Corresponding) [SCIE, IF 4.1]

6. Rajesh, M., Yan, WM.* & Yen, YK.* Solvothermal synthesis of two-dimensional graphitic carbon nitride/tungsten oxide nanocomposite: a robust electrochemical scaffold for selective determination of dopamine and uric acid. J Appl Electrochem (2022), 52, 1231–1248. [SCIE, IF 2.8] (Corresponding) https://doi.org/10.1007/s10800-022-01699-6.[SCIE, IF 2.9]

2021

7. Song-Jeng Huang, Philip Nathaniel Immanuel, Yi-Kuang Yen*, Ching-Lung Yen, Chi-En Tseng, Guan-Ting Lin, Che-Kuan Lin and Zhong-Xuan Huang, "Tungsten Disulfide Nanotube-Modified Conductive Paper-Based Chemiresistive Sensor for the Application in Volatile Organic Compounds’ Detection, " (2021) sensors, 21(18), 6121. [SCIE, IF 3.576] (Corresponding)  https://doi.org/10.3390/s21186121  

2020

8. Yi-Kuang Yen * and Chao-Yu Lai, "Portable Real-Time Detection of Pb(II) Using a CMOS MEMS-Based Nanomechanical Sensing Array Modified with PEDOT:PSS". (2020) Nanomaterials, 10, 2454. [SCIE, IF 4.324] (Corresponding) https://doi.org/10.3390/nano10122454  

9. Yi-Kuang Yen*, Kuan-Yi Lee, Chun-Yi Lin, Shu-Ting Zhang, Cheng-Wei Wang, and Ta-Yu Liu, "Portable nanohybrid paper-based chemiresistive sensor for free chlorine detection," (2020) ACS Omega, 5, 39, 25209–25215. September 21, 2020.   [SCIE, IF 2.87] (Corresponding) https://pubs.acs.org/doi/full/10.1021/acsomega.0c03366 

10. Yi‐Kuang Yen*, Chen‐Hsiang Chao and Ya‐Shin Yeh, "A Graphene-PEDOT:PSS Modified Paper-Based Aptasensor for Electrochemical Impedance Spectroscopy Detection of Tumor Marker, " (2020) Sensors, 20, 1372. [SCIE, IF 3.031] (Corresponding) 

11. Yi-Kuang Yen* and Chao-Yuan Chiu, "A CMOS MEMS-based Membrane-Bridge Nanomechanical Sensor for Small Molecule Detection, " (2020) Scientific Reports 10, 2931 . https://doi.org/10.1038/s41598-020-60057-8.  [SCI; IF 4.011] (Corresponding) 

2019

12. Kuan-Wei Li and Yi-Kuang Yen*, "Gentamicin Drug Monitoring for Peritonitis Patients by Using a CMOS-BioMEMS-Based Microcantilever Sensor, Biosensors and Bioelectronics," (2019), Biosensors and Bioelectronics, Vol 130, 1 April 2019, Pages 420-426.  https://doi.org/10.1016/j.bios.2018.09.014  [SCI; IF 8.173](Corresponding) 

2018

13. Ku, Y.-F.; Huang, L.-S.; Yen, Y.-K*. "A Real-Time Thermal Self-Elimination Method for Static Mode Operated Freestanding Piezoresistive Microcantilever-Based Biosensors. Biosensors (2018), Vol. 8, Issue 18, pp 1-10. [ ESCI , CiteScore 2017 (Scopus): 3.59 ](Corresponding) 

14. Jian-Wei Tseng, Chao-Yuan Liu, Yi-Kuang Yen, Johannes Belkner, Tobias Bremicker, Bernard Haochih Liu, Ta-Ju Sun, An-Bang Wang ,  "Screw extrusion-based additive manufacturing of PEEK " Materials & Design (2018) , Vol. 140, pp. 209-221.  [SCI; IF 4.36]

2017

15. Yi-Kuang Yen, Eyal Capua and Ron Naaman*, “Application of a GaAs-based sensor for detecting hemoglobin in gastrointestinal environments,” IEEE Sensors Journal, (2017), Vol. 17, Issue 3, pp. 660-666. [SCI; IF 2.52]

2016

16. Chao-Yuan Liu, De-Chao Lu, Yi-Wei Jiang, Yi-Kuang Yen, Shih-Chung Chang* and An-Bang Wang*, “Easy and Fast Western Blotting by Thin-Film Direct Coating with Suction,” Analytical chemistry (2016), Vol. 88, Issue 12, pp. 6349–6356. (Arthurs contributed equally to this work) [SCI; IF 5.886]

2015

17. Long-Sun Huang*, Christian Gunawan, Yi-Kuang Yen, and Kai-Fung Chang, “Direct Determination of a Small-Molecule Drug, Valproic Acid, by an Electrically-Detected Microcantilever Biosensor for Personalized Diagnostics,” Biosensors (2015), Vol. 5, Issue 1, pp. 37-50. [ ESCI , CiteScore 2017 (Scopus): 3.59 ]

2014

18. Yi-Kuang Yen, Yi-Wei Jiang, S. C. Chang*, and A. B. Wang*, “Western blotting by thin-film direct coating,” Analytical chemistry (2014) ,Vol. 86, Issue 10, pp. 5164-70. [SCI; IF 5.636]

19. Long-Sun Huang*, Yotsapoom Pheanpanitporn, Yi-Kuang Yen, Kai-Fung Chang, and Lung-Yi Lin, “Detection of the Antiepileptic Drug Phenytoin Using a Single Freestanding Piezoresistive Microcantilever for Therapeutic Drug Monitoring,” Biosensors and Bioelectronics (2014), Vol. 59, pp. 233-8. [SCI; IF 6.409]

2013

20. Yi-Kuang Yen, Yu-Cheng Lai, Wei-Ting Hong, Yotsapoom Pheanpanitporn, Chuin-Shan Chen and Long-Sun Huang*, “Electrical Detection of C-Reactive Protein Using a Single Free-Standing, Thermally Controlled Piezoresistive Microcantilever for Highly Reproducible and Accurate Measurements,” Sensors (2013), Vol. 13, Issue 8, pp. 9653-9668. [SCI E; IF 2.245]

21. Wang, A.–B*., Hsieh, Y.-W., Yen, Y.-K., Liou, H.-R., Pan, P.-T., Lai, S.-H., Xu, Y.-C., Chen, Y.-T., Huang, J.-M., “The development of a new ultra-thin coating head and its application,” Machine Tool and Accessory Magazine (2013), Vol. 5, pp. 58–60. [In Chinese]

2009

22. Y. K. Yen, C. Y. Huang, C. H. Chen, C. M. Hung, K. C. Wu, C. K. Lee, and L. S. Huang*, “A novel , electrically protein-manipulated microcantilever biosensor for enhancement of capture antibody immobilization,” Sensors and Actuators: B. Chemical (2009), Vol. 141, Issue 2, pp. 498–505. [SCI; IF 3.083]

CONFERENCE PAPERS/ PRESENTATIONS

1. 陳俞瑄,  顏毅廣*, 以微流體裝置製備無機奈米管複合材導電生物絲, 中華民國力學學會年會暨第四十五屆全國力學會議, 線上，2021年11月18-19.

2. 李巧薇, 顏毅廣*, 雷射激發石墨烯/聚苯胺複合紙基化學電阻式鎘離子感測器之研究, 中華民國力學學會年會暨第四十五屆全國力學會議, 線上，2021年11月18-19.

3. 高振庭, 顏毅廣*, 利用聚苯乙烯磺酸鹽修飾之橋狀薄膜式奈米力學感測器應用於檢測水質與人體血清中的鉛離子之研究, 中華民國力學學會年會暨第四十五屆全國力學會議, 線上，2021年11月18-19.

4. C.H. Hsiang and Y.K. Yen*, Tunable spider silk fibers spinning by using a 3D printing biomimic microfluidic device,  2021 International Conference on Smart Sensors, Online, 14-15  October, 2021. (Corresponding , Oral)

5. A.M. Londhe and Yi-Kuang Yen*, Highly-sensitive detection of Cd2+ ions based on Prussian blue-PEDOT-loaded laser scribed graphene modified glassy carbon electrode, 2021 International Conference on Smart Sensors, Online, 14-15  October, 2021. (Corresponding , Oral)

6. Tzu-Chi Shen, Chin-Fang Tseng and Yi-Kuang Yen*, A portable paper-based ELISA sensing platform with smartphone quantitative analysis for the detection of TNF-α, 2021 International Conference on Smart Sensors, Online, 14-15  October, 2021. (Corresponding , Oral)

7. Y.S. Yeh and Y.K. Yen*, Detection of Interferon gamma using graphene/conductive polymer modified paper-based electrochemical aptasensor. 31st Anniversary World Congress on Biosensors - Online, 26-29 July, 2021. (Corresponding , oral presenter, session chair)

8. Yan-Lin Chen, Dong-Ye Wu, Chang-Dian Liu and Yi-Kuang Yen*,  A CMOS MEMS Based Membrane-bridge Nanomechanical Sensor for Caffeine Detection. 2020 Annual Meeting for the Society of Theoretical and Applied Mechanics of the Republic of China and the 44rd National Conference on Theoretical and Applied Mechanics, Yilan, Taiwan, (2020, Nov). (Corresponding) 

9. Gideon George Durai, Chih-Hsuan Hsiang, Yi-Kuang Yen*. Pumpless Microfluidic Device for Measuring Blood Coagulation Reaction Time. ICSS 2020 International Conference on Smart Sensors, Kaohsiung, Taiwan,  (2020, Oct). (Corresponding) 

10. C.H. Chao and Y.K. Yen*, "Electrochemical aptamer sensors based on a novel composite paper electrode for carcinoembryonic antigen detection," 6th International Conference on Bio-Sensing Technology  (BITE2019) , Kuala Lumpur, Malaysia, June 16-19, 2019. (Corresponding) 

11. Y.S. Chen and Y.K. Yen*,  "A vibrated self-sensing CMOS MEMS microcantilever sensor for whole blood coagulation time monitoring, " 6th International Conference on Bio-Sensing Technology  (BITE2019) , Kuala Lumpur, Malaysia, June 16-19, 2019. (Corresponding) 

12. Chao-Yuan Chiu and Yi-Kuang Yen*, "Phenytoin Drug Monitoring by using a CMOS-MEMS Based Piezoresistive Membrane-Bridge Biosensor, " Automation 2018, Taichung City, Taiwan, December 6-8, 2018. (Corresponding) (Best paper award)

13. Chao-yu Lai  and Yi-Kuang Yen *,  "Hybrid Conductive Polymer Paper Based Lead Ion Sensor, " Microfluidics 2018 , Heidelberg, Germany, July  15-17, 2018.(Corresponding and presenter) 

14. Zi-Kuan Yang, Yi-Hong Shih  and Yi-Kuang Yen *, "An oscillated CMOS MEMS microcantilever sensor for monitoring blood clotting time in human plasma," Biosensors 2018, Miami , Jun   12–15, 2018 . (Corresponding)  

15. Kuan-Wei Li, Chao-Yuan Chiu, Long-Sun Huang and Yi-Kuang Yen*, "Detection of Gentamicin for Patients with Peritonitis by using a CMOS-BioMEMS Based Microcantilever Sensor, " Biosensors 2018, Miami , Jun   12–15, 2018 . (Corresponding) 

16. Y-K. Yen, E. Capua, R. Naaman, “A hybrid organic GaAs-based biosensor for detecting gastrointestinal haemorrhages,” Biosensors 2016, Gothenburg, Sweden, May 25-27, 2016. (presenter)

17. Y.K. Yen, Y.C. Chang, H.Q. Lin, C.S. Chen, L.S. Huang, “Externally Actuated, Self-sensing Microcantilever Sensor for Miniaturized Point-of-care Coagulation Monitoring,” 24th Anniversary World Congress on Biosensors, Melbourne, Australia, May 27-30,2014. (Oral presenter)

18. Fu, H.-Y., Yen, Y.-K., Hsieh, Y.-W., Liou, H.-R., Wang, A.–B., “The Development of Flatness Precision Grinding Machine and Its Investigation of Grinding Accuracy,” Proceedings of the 30th National Conference on Mechanical Engineering of CSME, ILan County, Taiwan, December 6-7, 2013. (Oral presenter)

19. Yu-Ju Liu, Tzu-Ling Chen, Shu-Hung Lai, Yu-Wen Hsieh, Yi-Kuang Yen, and An-Bang, Wang, “Design and Test of a Novel Coating Technology for Multilayer Ceramic Capacitor (MLCC)” 4th International Symposium on Advanced Ceramics and Technology for Sustainable Energy Applications toward a Low Carbon Society (ACTSEA 2013), Taipei, Taiwan, Nov. 10-13, 2013.

20. L.-S. Huang*, Y. Pheanpanitporn, L.-Y. Lin, Y.-K. Yen, D.-M. Lai, and C.-K. Wang, “Nanomechanical Drug Detection of Phenytoin Using a Single Free-standing Piezoresistive Microcantilever for Anti-epileptic Therapeutic Drug Monitoring,” The 5th International Symposium on Microchemistry and Microsystems, Xiamen, China , May 16-19, 2013.

21. Y. K. Yen, Yi-Wei Jiang, S. C. Chang, A. B. Wang, “Biomaterial Thin Film Coating Using an Ultra Thin Advanced Coater”, The 5th Asian Coating Workshop, Seoul, Korea, May 9-10, 2013. (Oral presenter)

22. Po-Ting Pan, Yi-Kuang Yen, An-Bang Wang*, Chih-Lei Chen, and Wen-Jie Cheng, “The development and application of capillary coating technology in OLED display,” The 5th Asian Coating Workshop, Seoul, Korea, May 9-10, 2013.

23. Long-Sun Huang, Christian Gunawan, Yi-Kuang Yen, Chuin-Shan Chen, Chorng-Kuang Wang, Dar-Ming Lai, “Piezoresistive Nanomechanical Biosensor for Anti-epileptic Drug Detection of Valproic Acid in Therapeutic Drug Monitoring”, Proceedings of Nanomechanical Sensing Workshop, Stanford University, CA, USA, May 1-3, 2013.

24. Y.F. Ku, Y.K. Yen, P.Y. Lin, L.S. Huang, “Self Thermal Elimination of Nanomechanics-based Biosensor Using a Single Free-standing Piezoresistive Microcantilever”, ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, Houston, USA, 2010. (Oral presenter)

25.  Y.K. Yen, Y.F. Ku, P.Y. Lin, H.C. Lee, L.S. Huang, “A Single Free-standing Microcantilever C-reactive Protein Sensor with Elimination of Thermal Effect”, The 3rd IEEE International Conference on Nano/Molecular Medicine and Engineering, Tainan, Taiwan, 2009. (Oral presenter)

26. T.-S. Chen, Y.-K. Yen, W.-P. Shih, and L.-S. Huang, “Blood separation filter integrated with micro-cantilever biosensor on a microchannel chip,” The 10th International Conference on Automation Technology, Tainan, Taiwan, June 27-29, 2009.

27. Yi-Kuang Yen, Yun-Qing Song, Hui-Jun Huang, Long-Sun Huang, Ming-Fong Chen, Fu- Shan Zhao, Cheng-Yan Gao, Wen-Bin Shih and Hong-Wei Qiu, “The Telemedicine and Tele-health Care System Disease Patterns - in Cardiovascular Disease, “ Wisdom, Quality, Good life Conference, Taipei, Taiwan, Jan 19-21, 2009, pp. 53-57. [In Chinese]

28. Y.-K. Yen, C.-M Hung, Y.-C. Lai, Y.-H. Lin, and L.-S. Huang, “Biochemical Effect of a Microcantilever Immunosensor with Integrated Electrical Detection”, Biosensors 2008: The Tenth World Congress on Biosensors, Shanghai, China, May 14-16, 2008.

29. Y.-K. Yen, C.-M Hung, Y.-C. Lai, Y.-H. Lin, and L.-S. Huang, “Fabrication and PCB-based Package of Disposable Microcantilever-based Sensor for Biosensing Applications,” The 4th APCOT Conference, Tainan, Taiwan, June 22-25, 2008

30. Y.-K. Yen, C.-H. Chen, C.-M. Huang, K.-C. Wu, C.-K. Lee, S. Lin and L.-S. Huang, “A Novel, Electrically Protein-manipulated Microcantilever Biosensor with Selective Protein Deposition,” Biosensors 2006: The Ninth World Congress on Biosensors, Toronto, Canada, May 10-12, 2006.

31. Y.K. Yen, J.Y. Lee, M.C. Kuo, L.S. Huang, “The application of an innovative MEMS protein chip in real-time total internal reflection fluorescence microscopy,” Proceedings of the 2005 IEEE, International Conference on Mechatronics, Taipei, Taiwan, 2005, p. 280.

32. C.-S. Chang, T.-S. Chu, L.-S. Huang, C.-Y. Chang, S.-Y. Zeng, M.-H. Wen, and Y.K. Yen, “A Novel Addressable Switching Micro Corner Cube Array for Free-space Optical Applications,” IEEE MEMS 2003, pp. 279-282, Kyoto, Japan, 2003.

PATENTS

1. 
   

2. 顏毅廣 ; 張育禎 ; 林豪駸, 振動式量測凝血反應時間之系統, ROC Patent No.I662282 (2019/06/11~2038/10/18)

3. Long-Sun Huang, Yi-Kuang Yen, Yu-Fu Ku, Guan Shu, Guang-Zhong Wu, Shiming Lin, Pin-Yan Lin, Apparatus with temperature self-compensation and method thereof. U. S. Patent 8,419,217 B2.

4. Long-Sun Huang, Yi-Kuang Yen, Yu-Fu Ku, Guan Shu, Guang-Zhong Wu, Shiming Lin, Pin-Yan Lin, Apparatus with temperature self-compensation and method thereof. ROC Patent No. I420537 (2013/012 / 21 ~ 2029/12/28).

5. Long-Sun Huang, Yi-Kuang Yen, Ming-Fong Chen, Yi-Lun Ho, Fu- Shan Zhao, Cheng-Yan Gao, Ming-Hui Jin, Yan-Hong Zong-Xian Lin, Xian-Guo Wu, Telemedicine and tele-health care system and its data transmission method, ROC Patent No. I343798 (2011/06 / 21 ~ 2027/12/06).

6.  Long-Sun Huang, Chih-Kung Lee, Shih-Yuan Lee, Kuang-Chong Wu, Yi-Kuang Yen, Micro-sensor for sensing chemical substance, ROC Patent No. I346777 (2011/08/11 ~ 2027/07/19).

7. Long-Sun Huang, Chih-Kung Lee, Shih-Yuan Lee, Kuang-Chong Wu, Yi-Kuang Yen, Micro-sensor for sensing chemical substance, U. S. Patent 7,730,767 B2.